Mark Y. Sangster, Ph.D.

Mark Y. Sangster, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 609
Rochester, NY 14642

Journal Articles

Showing all 46 journal articles available.

2014 Jan
Alam S, Knowlden ZA, Sangster MY, Sant AJ. "CD4 T cell help is limiting and selective during the primary B cell response to influenza virus infection." Journal of virology.. 2014 Jan; 88(1):314-24. Epub 2013 Oct 23.
2014
Miao H, Sangster MY, Livingstone AM, Hilchey SP, Zhang L, Topham DJ, Mosmann TR, Holden-Wiltse J, Perelson AS, Wu H, Zand MS. "Modeling the dynamics and migratory pathways of virus-specific antibody-secreting cell populations in primary influenza infection." PloS one. 2014 9(8):e104781. Epub 2014 Aug 29.
2013 Jun
Sangster MY, Baer J, Santiago FW, Fitzgerald T, Ilyushina NA, Sundararajan A, Henn AD, Krammer F, Yang H, Luke CJ, Zand MS, Wright PF, Treanor JJ, Topham DJ, Subbarao K. "B cell response and hemagglutinin stalk-reactive antibody production in different age cohorts following 2009 H1N1 influenza virus vaccination." Clinical and vaccine immunology : CVI.. 2013 Jun; 20(6):867-76. Epub 2013 Apr 10.
2013 Jan 15
He XS, Sasaki S, Baer J, Khurana S, Golding H, Treanor JJ, Topham DJ, Sangster MY, Jin H, Dekker CL, Subbarao K, Greenberg HB. "Heterovariant cross-reactive B-cell responses induced by the 2009 pandemic influenza virus A subtype H1N1 vaccine." The Journal of infectious diseases.. 2013 Jan 15; 207(2):288-96. Epub 2012 Oct 29.
2012
Sundararajan A, Huan L, Richards KA, Marcelin G, Alam S, Joo H, Yang H, Webby RJ, Topham DJ, Sant AJ, Sangster MY. "Host differences in influenza-specific CD4 T cell and B cell responses are modulated by viral strain and route of immunization." PloS one. 2012 7(3):e34377. Epub 2012 Mar 23.
2011 Nov 22
Sharma S, Sundararajan A, Suryawanshi A, Kumar N, Veiga-Parga T, Kuchroo VK, Thomas PG, Sangster MY, Rouse BT. "T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses." Proceedings of the National Academy of Sciences of the United States of America.. 2011 Nov 22; 108(47):19001-6. Epub 2011 Nov 03.
2011 Nov
Su X, Sangster MY, D'Souza DH. "Time-dependent effects of pomegranate juice and pomegranate polyphenols on foodborne viral reduction." Foodborne pathogens and disease. 2011 Nov; 8(11):1177-83. Epub 2011 Jul 21.
2010 Oct
Sundararajan A, Ganapathy R, Huan L, Dunlap JR, Webby RJ, Kotwal GJ, Sangster MY. "Influenza virus variation in susceptibility to inactivation by pomegranate polyphenols is determined by envelope glycoproteins." Antiviral research.. 2010 Oct; 88(1):1-9. Epub 2010 Jul 14.
2010 Mar 2
Joo HM, He Y, Sundararajan A, Huan L, Sangster MY. "Quantitative analysis of influenza virus-specific B cell memory generated by different routes of inactivated virus vaccination." Vaccine.. 2010 Mar 2; 28(10):2186-94. Epub 2010 Jan 05.
2010
Su X, Sangster MY, D'Souza DH. "In vitro effects of pomegranate juice and pomegranate polyphenols on foodborne viral surrogates." Foodborne pathogens and disease. 2010 7(12):1473-9. Epub 2010 Aug 31.
2009 Nov 5
Li Z, Wang H, Xue L, Shin DM, Roopenian D, Xu W, Qi CF, Sangster MY, Orihuela CJ, Tuomanen E, Rehg JE, Cui X, Zhang Q, Morse HC, Morris SW. "Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma." Blood.. 2009 Nov 5; 114(19):4158-68. Epub 2009 Aug 20.
2009 Apr 15
Zeng J, Joo HM, Rajini B, Wrammert JP, Sangster MY, Onami TM. "The generation of influenza-specific humoral responses is impaired in ST6Gal I-deficient mice." The Journal of immunology : official journal of the American Association of Immunologists.. 2009 Apr 15; 182(8):4721-7.
2008 Mar 4
Joo HM, He Y, Sangster MY. "Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumonia." Proceedings of the National Academy of Sciences of the United States of America.. 2008 Mar 4; 105(9):3485-90. Epub 2008 Feb 25.
2007 Mar 30
Vanitha DJ, Joo HM, Rouse BT, Sangster MY. "Quantitative analysis of herpes simplex virus type 1-specific memory B cells generated by different routes of infection." Virology.. 2007 Mar 30; 360(1):136-42. Epub 2006 Nov 17.
2006 Jun 30
Li X, Vanitha DJ, Joo HM, He Y, Rouse BT, Sangster MY. "A strategy for selective, CD4+ T cell-independent activation of virus-specific memory B cells for limiting dilution analysis." Journal of immunological methods.. 2006 Jun 30; 313(1-2):110-8. Epub 2006 May 15.
2005 Apr
Lipatov AS, Andreansky S, Webby RJ, Hulse DJ, Rehg JE, Krauss S, Perez DR, Doherty PC, Webster RG, Sangster MY. "Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses." The Journal of general virology.. 2005 Apr; 86(Pt 4):1121-30.
2003 Oct 6
Sangster MY, Riberdy JM, Gonzalez M, Topham DJ, Baumgarth N, Doherty PC. "An early CD4+ T cell-dependent immunoglobulin A response to influenza infection in the absence of key cognate T-B interactions." The Journal of experimental medicine.. 2003 Oct 6; 198(7):1011-21. Epub 2003 Sep 29.
2001 May 22
Marshall DR, Turner SJ, Belz GT, Wingo S, Andreansky S, Sangster MY, Riberdy JM, Liu T, Tan M, Doherty PC. "Measuring the diaspora for virus-specific CD8+ T cells." Proceedings of the National Academy of Sciences of the United States of America.. 2001 May 22; 98(11):6313-8. Epub 2001 May 08.
2001 Apr 29
Doherty PC, Christensen JP, Belz GT, Stevenson PG, Sangster MY. "Dissecting the host response to a gamma-herpesvirus." Philosophical transactions of the Royal Society of London. Series B, Biological sciences.. 2001 Apr 29; 356(1408):581-93.
2000 Jul
Wang D, Feng J, Wen R, Marine JC, Sangster MY, Parganas E, Hoffmeyer A, Jackson CW, Cleveland JL, Murray PJ, Ihle JN. "Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors." Immunity.. 2000 Jul; 13(1):25-35.
2000 Feb 15
Sangster MY, Topham DJ, D'Costa S, Cardin RD, Marion TN, Myers LK, Doherty PC. "Analysis of the virus-specific and nonspecific B cell response to a persistent B-lymphotropic gammaherpesvirus." The Journal of immunology : official journal of the American Association of Immunologists.. 2000 Feb 15; 164(4):1820-8.
1999 Nov 1
Marshall D, Sealy R, Sangster M, Coleclough C. "TH cells primed during influenza virus infection provide help for qualitatively distinct antibody responses to subsequent immunization." The Journal of immunology : official journal of the American Association of Immunologists.. 1999 Nov 1; 163(9):4673-82.
1999 Apr
Urosevic N, Silvia OJ, Sangster MY, Mansfield JP, Hodgetts SI, Shellam GR. "Development and characterization of new flavivirus-resistant mouse strains bearing Flv(r)-like and Flv(mr) alleles from wild or wild-derived mice." The Journal of general virology.. 1999 Apr; 80 ( Pt 4):897-906.
1999 Feb
Moriggl R, Topham DJ, Teglund S, Sexl V, McKay C, Wang D, Hoffmeyer A, van Deursen J, Sangster MY, Bunting KD, Grosveld GC, Ihle JN. "Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells." Immunity.. 1999 Feb; 10(2):249-59.
1998 Nov
Brown MP, Topham DJ, Sangster MY, Zhao J, Flynn KJ, Surman SL, Woodland DL, Doherty PC, Farr AG, Pattengale PK, Brenner MK. "Thymic lymphoproliferative disease after successful correction of CD40 ligand deficiency by gene transfer in mice." Nature medicine.. 1998 Nov; 4(11):1253-60.
1998 Apr
Shellam GR, Sangster MY, Urosevic N. "Genetic control of host resistance to flavivirus infection in animals." Revue scientifique et technique (International Office of Epizootics). 1998 Apr; 17(1):231-48.
1998 Jan
Bunting KD, Sangster MY, Ihle JN, Sorrentino BP. "Restoration of lymphocyte function in Janus kinase 3-deficient mice by retroviral-mediated gene transfer." Nature medicine.. 1998 Jan; 4(1):58-64.
1998
Sangster MY, Mackenzie JS, Shellam GR. "Genetically determined resistance to flavivirus infection in wild Mus musculus domesticus and other taxonomic groups in the genus Mus." Archives of virology.. 1998 143(4):697-715.
1997 Sep 15
Walker WS, Castrucci MR, Sangster MY, Carson RT, Kawaoka Y. "HEL-Flu: an influenza virus containing the hen egg lysozyme epitope recognized by CD4+ T cells from mice transgenic for an alphabeta TCR." The Journal of immunology : official journal of the American Association of Immunologists.. 1997 Sep 15; 159(6):2563-6.
1997 Aug 15
Sangster MY, Mo XY, Sealy R, Coleclough C. "Matching antibody class with pathogen type and portal of entry: cognate mechanisms regulate local isotype expression patterns in lymph nodes draining the respiratory tract of mice inoculated with respiratory viruses, according to virus replication competence and site of inoculation." The Journal of immunology : official journal of the American Association of Immunologists.. 1997 Aug 15; 159(4):1893-902.
1997 Apr
Hurwitz JL, Soike KF, Sangster MY, Portner A, Sealy RE, Dawson DH, Coleclough C. "Intranasal Sendai virus vaccine protects African green monkeys from infection with human parainfluenza virus-type one." Vaccine.. 1997 Apr; 15(5):533-40.
1997 Mar
Mo XY, Tripp RA, Sangster MY, Doherty PC. "The cytotoxic T-lymphocyte response to Sendai virus is unimpaired in the absence of gamma interferon." Journal of virology.. 1997 Mar; 71(3):1906-10.
1997 Mar
Mo XY, Sangster MY, Tripp RA, Doherty PC. "Modification of the Sendai virus-specific antibody and CD8+ T-cell responses in mice homozygous for disruption of the interleukin-4 gene." Journal of virology.. 1997 Mar; 71(3):2518-21.
1996 Jul 11
Thierfelder WE, van Deursen JM, Yamamoto K, Tripp RA, Sarawar SR, Carson RT, Sangster MY, Vignali DA, Doherty PC, Grosveld GC, Ihle JN. "Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells." Nature.. 1996 Jul 11; 382(6587):171-4.
1996 Jun
Hall RA, Brand TN, Lobigs M, Sangster MY, Howard MJ, Mackenzie JS. "Protective immune responses to the E and NS1 proteins of Murray Valley encephalitis virus in hybrids of flavivirus-resistant mice." The Journal of general virology.. 1996 Jun; 77 ( Pt 6):1287-94.
1996 Apr 18
Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, Chu C, Quelle FW, Nosaka T, Vignali DA, Doherty PC, Grosveld G, Paul WE, Ihle JN. "Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene." Nature.. 1996 Apr 18; 380(6575):630-3.
1996 Feb
Topham DJ, Tripp RA, Sarawar SR, Sangster MY, Doherty PC. "Immune CD4+ T cells promote the clearance of influenza virus from major histocompatibility complex class II -/- respiratory epithelium." Journal of virology.. 1996 Feb; 70(2):1288-91.
1995 Sep 10
Sangster M, Smith FS, Coleclough C, Hurwitz JL. "Human parainfluenza virus type 1 immunization of infant mice protects from subsequent Sendai virus infection." Virology.. 1995 Sep 10; 212(1):13-9.
1995 Sep
Mo XY, Sangster M, Sarawar S, Coleclough C, Doherty PC. "Differential antigen burden modulates the gamma interferon but not the immunoglobulin response in mice that vary in susceptibility to Sendai virus pneumonia." Journal of virology.. 1995 Sep; 69(9):5592-8.
1995 Feb 20
Sangster M, Hyland L, Sealy R, Coleclough C. "Distinctive kinetics of the antibody-forming cell response to Sendai virus infection of mice in different anatomical compartments." Virology.. 1995 Feb 20; 207(1):287-91.
1994 Sep
Hyland L, Sangster M, Sealy R, Coleclough C. "Respiratory virus infection of mice provokes a permanent humoral immune response." Journal of virology.. 1994 Sep; 68(9):6083-6.
1994 Aug 1
Sarawar SR, Sangster M, Coffman RL, Doherty PC. "Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype." The Journal of immunology : official journal of the American Association of Immunologists.. 1994 Aug 1; 153(3):1246-53.
1994 Jan
Sangster MY, Urosevic N, Mansfield JP, Mackenzie JS, Shellam GR. "Mapping the Flv locus controlling resistance to flaviviruses on mouse chromosome 5." Journal of virology.. 1994 Jan; 68(1):448-52.
1993 Jan
Sangster MY, Heliams DB, MacKenzie JS, Shellam GR. "Genetic studies of flavivirus resistance in inbred strains derived from wild mice: evidence for a new resistance allele at the flavivirus resistance locus (Flv)." Journal of virology.. 1993 Jan; 67(1):340-7.
1991 Aug
Weaver D, Skinner S, Walker L, Sangster M. "Phenotypic inhibition of the renin-angiotensin system, emergence of the Ren-2 gene, and adaptive radiation of mice." General and comparative endocrinology. 1991 Aug; 83(2):306-15.
1986
Sangster MY, Shellam GR. "Genetically controlled resistance to flaviviruses within the house mouse complex of species." Current topics in microbiology and immunology.. 1986 127:313-8.

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