Research Profile Journal Articles
Robert Stanley Freeman, Ph.D.

Robert Stanley Freeman, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 711
Rochester, NY 14642

Lab Description

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Bio

Dr. Freeman's biographical information is not currently available.

Awards & Honors

Alumni Award for Excellence in Graduate Education | University of Rochester 2008
Paul Stark Professor of Pharmacology | University of Rochester 1996 - 2000
National Research Service Award, Postdoctoral Fellowship | NIH/NINDS | Washington University School of Medicine 1992 - 1994
Merck Award | University of Delaware 1985
American Institute of Chemists Award | University of Delaware 1985

Recent Journal Articles

Showing the 5 most recent journal articles. 40 available »

Guo H, Barrett TM, Zhong Z, Fernandez JA, Griffin JH, Freeman RS, Zlokovic BV. "Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway." Molecular neurodegeneration. 2011; 6Epub 2011 Feb 03.
Zhong Z, Wang Y, Guo H, Sagare A, Fernández JA, Bell RD, Barrett TM, Griffin JH, Freeman RS, Zlokovic BV. "Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like region." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2010; 30(46):15521-34.
Lomb DJ, Desouza LA, Franklin JL, Freeman RS. "Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympathetic neurons." Molecular pharmacology. 2009; 75(5):1198-209. Epub 2009 Feb 09.
Guo Y, Schoell MC, Freeman RS. "The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL)." Oncogene. 2009; 28(16):1864-74. Epub 2009 Mar 23.
Xie L, Xiao K, Whalen EJ, Forrester MT, Freeman RS, Fong G, Gygi SP, Lefkowitz RJ, Stamler JS. "Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL." Science signaling. 2009; 2(78):ra33. Epub 2009 Jul 07.

Current Appointments

Professor - Department of Pharmacology and Physiology (SMD) - Primary
Professor - Cancer Center

Education

PhD | Biochemistry | Univ of Cal San Diego1991
MS | Biochemistry | Univ of Cal San Diego1987
BS | Chemistry | University of Delaware1985