URMC Labs - Clinical Laboratory Services

Liver Transplant Pathology

The Liver Transplant Pathology lab offers prompt, skillful reading of core needle biopsies. Over the past three years (2008-2011) we have diagnosed 537 liver allograft and 1677 native liver core biopsies.

Core needle biopsies are prepared in state-of-the-art facilities which include VIP and microwave processors. Four cryostats are available for frozen sections and research.

Biopsies are read by a pathologist the day after procurement with a same day interpretation available for urgent cases and for all liver transplant patients.

Our immunohistochemistry laboratory offers a wide range of stains including both mono- and polyclonal antibodies and in situ hybridization. Tissue microarrays are stained routinely.

Our facilities include an electron microscopy unit, a nucleic acid core laboratory, a molecular imaging core facility, a biospecimen repository with vapor phase freezers and a large modern vivarium.

Liver Transplant Program

The liver transplant program at URMC includes four surgeons and has been in place for 20 years. The program has performed more than 1450 cases to date. We currently average 50-75 transplants and 30 hepatobiliary procedures per year.

Three thousand pre- and post-transplant patients are seen in our clinic each year, with over 500 newly referred patients. Liver transplant is a multidisciplinary program with dedicated infectious disease specialists, hepatologists, psychiatrists, nutritionists, social workers and pharmacists.

Scope of Disorders Diagnosed

Native Livers:

  • Hepatitis: acute and chronic viral hepatitis (all types)- autoimmune, drug, toxic, parasitic, granulomatous hepatitis
  • Chronic cholestatic disorders (PBC, PSC)
  • Congenital and pediatric biliary disorders
  • Alcoholic liver disease
  • NAFLD
  • Wilson’s Disease, metabolic disorders
  • Tumors: hepatocellular carcinoma, cholangiocarcinoma, metastatic cancer
    Sarcomas, adenomas, FNH

Liver Allografts:

  • Acute and chronic rejection
  • Recurrent and de novo hepatitis
  • Plasma cell hepatitis
  • Biliary obstruction and stricture
  • Venous outlet obstruction
  • Recurrent tumor
  • Ischemic/reperfusion injury
  • Recurrent PSC, PBC

Liver Transplant Pathologists

Contact Us

For more information or to request our services, please contact (name), at (585) 275-3191.