Aquavella Lab

James V. Aquavella, MD

  • M.D. 1957 Italy - Fac Med U Naples
  • Professor: Department of Ophthalmology (SMD)
  • Board Ceritfied Specialties: Ophthalmology; American Board of Ophthalmology
  • Download full CV JVA_CV

Research Overview

Dr. James Aquavella has organized a group of basic scientists including Geunyoung Yoon, Krystel Huxlin, and Jim Zavislan to evaluate human tear film dynamics and its relationship to clinical dry eye syndrome. Utilizing three new technologies developed at the Flaum Eye Institute, including wave front analysis, OCT, and ellipsometry, the team is measuring variations in tear film thickness and composition related to the normal blink reflex during altered environmental conditions. This multidisciplinary approach -- which may lead to a better diagnosois and treatment of clinical dry eye -- is a collaborative effort between the Eye Institute and the departments of immunology, oral biology, optics, and dermatology.

Recent Publications

Showing 5 of 24 journal articles.

Herzlich AA; Aquavella JV. "Infant keratoprosthesis." International ophthalmology clinics. 2013; 53(2):71-7.

Huang J; Lee KS; Clarkson E; Kupinski M; Maki KL; Ross DS; Aquavella JV; Rolland JP. "Phantom study of tear film dynamics with optical coherence tomography and maximum-likelihood estimation." Optics letters.. 2013; 38(10):1721-3.

Kottaiyan R; Yoon G; Wang Q; Yadav R; Zavislan JM; Aquavella JV. "Integrated multimodal metrology for objective and noninvasive tear evaluation." The ocular surface. 2012; 10(1):43-50. Epub 2012 Jan 08.

Tung CI; Kottaiyan R; Koh S; Wang Q; Yoon G; Zavislan JM; Davio SR; Aquavella JV. "Noninvasive, objective, multimodal tear dynamics evaluation of 5 over-the-counter tear drops in a randomized controlled trial." Cornea.. 2012; 31(2):108-14.

Gensheimer WG; Kleinman DM; Gonzalez MO; Sobti D; Cooper ER; Smits G; Loxley A; Mitchnick M; Aquavella JV. "Novel formulation of glycerin 1% artificial tears extends tear film break-up time compared with Systane lubricant eye drops." Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.. 2012; 28(5):473-8. Epub 2012 May 03.

More articles...


James Aquavella, MD
University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave., Box 659
Rochester, NY 14642

Office: (585) 273-3937
Fax: (585) 276-0292
Office locaton: 3-3033


Geunyoung Yoon, Ph.D.

Geunyoung Yoon, Ph.D.

Krystel Huxlin, Ph.D.

Krystel Huxlin, Ph.D.

James Zavislan, Ph.D.

Jim Zavislan, Ph.D.