Principal Investigator

Dmitri N. Ermolenko, Ph.D. University of Rochester work Rochester NY Dmitri_Ermolenko@urmc.rochester.edu

Collaborators

Peter V. Cornish, Ph.D. Biochemistry University of Missouri Research Focus: Dynamics and assembly of ribonucleoprotein complexes utilizing both NMR and single molecule FRET.

Gloria Culver, Ph.D. Biology University of Rochester Research Focus: Assembly of the E. coli 30S ribosomal subunit.

Nikolaus Grigorieff, Ph.D. Biochemistry Brandeis University Research Focus: High resolution electron cryo-microscopy of membrane proteins and channels.

Andrei Korostelev, Ph.D. Biochemistry and Molecular Pharmacology University of Massachusetts Research Focus: Using X-ray crystallography to obtain snapshots of different functional states of the ribosome and biochemistry.

P. Clint Spiegel, Ph.D. Biochemistry Western Washington University Research Focus: Understanding the structural and functional properties of RNA.

Recent Publications

1. Ermolenko DN
2. Cornish PV
3. Ha T
4. Noller HF
(2013 Feb 01). Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation. RNA. 19, 158-66.
1. Rudenko MI
2. Holmes MR
3. Ermolenko DN
4. Lunt EJ
5. Gerhardt S
6. Noller HF
7. Deamer DW
8. Hawkins A
9. Schmidt H
(2011 Nov 15). Controlled gating and electrical detection of single 50S ribosomal subunits through a solid-state nanopore in a microfluidic chip. Biosens Bioelectron. 29, 34-9.
1. Ermolenko DN
2. Noller HF
(2011 Apr 01). mRNA translocation occurs during the second step of ribosomal intersubunit rotation. Nat Struct Mol Biol. 18, 457-62.

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