Welcome to the Jumping Frog Lab
The overall goal of our research is to understand the co-evolutionary relationships between the structure of selected molecules (e.g., non-classical MHC class Ib molecules) and their functions in innate and adaptive immunity against tumors and viruses using the frog Xenopus as animal model.
Current Research Projects
- Retention of duplicated ITAM-containing transmembrane signaling subunits in the tetraploid amphibian species Xenopus laevis.Dev Comp Immunol. 53, 158-68. (2015 Nov 01).
- Characterization of Frog Virus 3 knockout mutants lacking putative virulence genes.Virology. 485, 162-170. (2015 Aug 07).
- Nonclassical MHC-Restricted Invariant Vα6 T Cells Are Critical for Efficient Early Innate Antiviral Immunity in the Amphibian Xenopus laevis.J Immunol. 195, 576-86. (2015 Jul 15).