Journal Clubs

The CMSR offers several Journal Clubs that are designed to be an integral component of graduate and post-doctoral training and education in the basic biomedical sciences. The Journal Clubs aim to provide trainees with a strong foundation and a broad grasp of current research questions and methodologies throughout the musculoskeletal biology field. The most recent advances in the fundamentals of osteoblast, osteoclast, and chondrocyte biology and the molecular mechanisms of musculoskeletal development and disease are presented and discussed.

The presenter(s) at each Journal Club meeting is a student or fellow and the paper to be discussed (not more than 6 months past publication) is chosen by the trainee in consultation with their faculty mentor. The paper is made available to all members of the CMSR a week in advance. During the meeting, the presenter(s) is responsible for providing enough background to bring the group up to speed on the specific topic and then moderates the group’s discussion of each figure and how it contributes to the overall conclusion(s) of the study. At least one faculty mentor is present at the meeting to observe and contribute if any clarification is necessary. Besides familiarizing the group with current literature, participants learn how to critically evaluate a study and envision novel experiments that might better address the hypothesis in question.

Room 1-8527, 1:00 pm - 3:00 pm (Every Other Thursday)

September 10, 2015 - "CD49f Acts as an Inflammation Sensor to Regulate Differentitation, Adhesion, and Migration of Human Mesenchymal Stem Cells" View article in PubMed

August 27, 2015 - "Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is requierd for stemness" View article in PubMed

August 13, 2015 - "Establishing criteria for human mensenchymal stem cell potency" View article in PubMed

July 30, 2015 - "Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation" View article in PubMed

June 25, 2015 - "Systemic infusion of mesenchymal stem cells improves cell-based bone regeneration via upregulation of regulatory T cells" View article in PubMed

View more articles of the Mesenchymal Stem Cell Journal Club

Room 1-8527, 8:30 am - 9:30 am (Every Thursday)

October 1, 2015 - " Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation" View article in PubMed

September 24, 2015 - "Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice" View article in PubMed

September 17, 2015 - "Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis" View article in PubMed

September 10, 2015 - "Intermittent Parathryoid Hormone Enhances Cancellous Osseointegration of a Novel Murine tibial Implant" View article in PubMed

September 3, 2015 - "Intermittent PTHrP (1-34) exposure augments chondrogenesis and reduces hypertrophy of mesenchymal stromal cells" View article in PubMed

August 27, 2015 - "PTH [1-34]-induced alterations of the subchondral bone provoke early osteoarthritis" View article in PubMed

August 20, 2015 - "Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification" View article in PubMed

July 30, 2015 - "The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment" View article in PubMed

July 23, 2015 - "IKKB in postnatal perichondrium remotely controls endochondral ossification of the growth plate through downregulation of MCP-5" View article in PubMed

July 16, 2015 - "Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation" View article in PubMed

View more articles of the Osteoarthritis, Fracture Healing and the Impact of Diabetes on The Skeleton Jounral Club

Upcoming Speakers

Neuman Room
(Room 1-6823)

October 7, 2015

8:30 am - 9:30 am

Javier Rangel-Moreno - Impact of neonatal exposure to gamma radiation on induction of adaptive immunity to influenza

Wei Zhou - PTH Improved Mesenchymal Stem Cell Undergo Angiogenesis and Neurogenic Dual Differentiations During Subacute Spinal Cord Injury

See Also This Week's Journal Clubs