Dr. Anandarajah is an adult rheumatologist who directs the Early Arthritis Clinic. His area of interest is in early rheumatoid arthritis with particular emphasis on outcome measures and comorbidities. He is also interested in osteoporosis and erosive osteoarthritis of the hand.

Faculty Appointments

Professor - Department of Medicine, Allergy/Immunology and Rheumatology (SMD)

Associate Chair for Wellness - Department of Medicine (SMD)

Credentials

Residency & Fellowship

Fellowship, Rheumatology, University of Rochester Medical Center. 2001 - 2003

Residency, Internal Medicine, Kindred Hospital of Delaware County. 1999 - 2001

Internship, Internal Medicine, Kindred Hospital of Delaware County. 1998 - 1999

Education

MBBS | University of Nigeria, Enugu Campus (Nigeria). 1990

Awards

Listed in Guide to America's Top Physicians. 2004 - 2005

Rheumatology Fellowship Grant. 2002 - 2003

Best Resident of the Year. 2000 - 2000

Research

Dr. Anandarajah has several clinical research interests. He is focusing on the role of imaging studies in the evaluation of inflammatory arthritis. He is also interested in early rheumatoid arthritis with particular emphasis on outcome measures and comorbidities as well as osteoporosis and erosive o...

Publications

Journal Articles

Impact of COVID-19 pandemic on social isolation and loneliness among minority populations.

Anandarajah A, Yi L, Anandarajah A, Shelton N, Feng C, Williams EM

The American journal of the medical sciences.. 2023 September 26 Epub 09/26/2023.

2022 American College of Rheumatology Guideline for Exercise, Rehabilitation, Diet, and Additional Integrative Interventions for Rheumatoid Arthritis.

England BR, Smith BJ, Baker NA, Barton JL, Oatis CA, Guyatt G, Anandarajah A, Carandang K, Chan KK, Constien D, Davidson E, Dodge CV, Bemis-Dougherty A, Everett S, Fisher N, Fraenkel L, Goodman SM, Lewis J, Menzies V, Moreland LW, Navarro-Millan I, Patterson S, Phillips LR, Shah N, Singh N, White D, AlHeresh R, Barbour KE, Bye T, Guglielmo D, Haberman R, Johnson T, Kleiner A, Lane CY, Li LC, Master H, Pinto D, Poole JL, Steinbarger K, Sztubinski D, Thoma L, Tsaltskan V, Turgunbaev M, Wells C, Turner AS, Treadwell JR

Arthritis & rheumatology.. 2023 May 25 Epub 05/25/2023.

2022 American College of Rheumatology Guideline for Exercise, Rehabilitation, Diet, and Additional Integrative Interventions for Rheumatoid Arthritis.

Arthritis care & research.. 2023 May 25 Epub 05/25/2023.

A Provider-based Approach to Address Racial Disparities in Lupus Clinical Trial Participation.

Wanty NI, Cooper DL, Simkus A, Twombly EC, McCalla S, Holtz SKD, Langford AT, Cozart T, Gorlitsky B, Moore C, Culton D, Richardson CT, Wardrop RM, Newcomb J, Aranow C, Lim S, Anandarajah A, Sheikh SZ

Arthritis care & research.. 2022 November 7 Epub 11/07/2022.

Dendritic cell-specific transmembrane protein is required for synovitis and bone resorption in inflammatory arthritis.

Garcia-Hernandez ML, Rangel-Moreno J, Garcia-Castaneda M, Kenney HM, Paine A, Thullen M, Anandarajah AP, Schwarz EM, Dirksen RT, Ritchlin CT

Frontiers in immunology.. 2022 13 :1026574. Epub 11/07/2022.

Identification and Characterization of a High-Need, High-Cost group among Hospitalized SLE patients.

Anandarajah A, Thirukumaran C, McCarthy K, McMahon S, Feng C, Ritchlin C

Arthritis care & research.. 2020 November 17 Epub 11/17/2020.

Designing an Intervention to Improve Management of High-Risk Lupus Patients Through Care Coordination.

Anandarajah A

Rheumatic diseases clinics of North America.. 2020 November 46 (4):723-734. Epub 08/20/2020.

Adopting the Quadruple Aim: The University of Rochester Medical Center Experience: Moving from Physician Burnout to Physician Resilience.

Anandarajah AP, Quill TE, Privitera MR.

American Journal of Medicine. 2018; 131: 8.

Hospitalization of patients with systemic lupus erythematosus is a major cause of direct and indirect healthcare costs.

Anandarajah AP, Luc M, Ritchlin CT.

Lupus. 2017; 26(7): 756.

PKK deficiency in B cells prevents lupus development in Sle lupus mice.

Oleksyn D, Zhao J, Vosoughi A, Zhao JC, Misra R, Pentland AP, Ryan D, Anolik J, Ritchlin C, Looney J, Anandarajah AP, Schwartz G, Calvi LM, Georger M, Mohan C, Sanz I, Chen L.

Immunol Lett. 2017; 185: 1-11.

The Relationship Between Focal and Generalized Bone Loss in Rheumatoid Arthritis.

Anandarajah AP, El-Taha M, Peng C

Current rheumatology reviews.. 2017 13 (2):152-157. Epub 1900 01 01.

Patients with rheumatoid arthritis in clinical remission manifest persistent joint inflammation on histology and imaging studies.

Anandarajah A, Thiele R, Giampoli E, Monu J, Seo GS, Feng C, Ritchlin C

The Journal of rheumatology.. 2014 November 41 (11):2153-60. Epub 10/01/2014.

Imaging in psoriatic arthritis.

Anandarajah A

Clinical reviews in allergy & immunology.. 2013 April 44 (2):157-65. Epub 1900 01 01.

Update on research and future directions of the OMERACT MRI inflammatory arthritis group.

Conaghan PG, McQueen FM, Bird P, Peterfy CG, Haavardsholm EA, Gandjbakhch F, Bøyesen P, Coates L, Ejbjerg B, Eshed I, Foltz V, Hermann KG, Freeston J, Lillegraven S, Lassere M, Wiell C, Anandarajah A, Duer-Jensen A, O'Connor P, Genant HK, Emery P, Ostergaard M

The Journal of rheumatology.. 2011 September 38 (9):2031-3. Epub 1900 01 01.

Development and preliminary validation of a magnetic resonance imaging joint space narrowing score for use in rheumatoid arthritis: potential adjunct to the OMERACT RA MRI scoring system.

Ostergaard M, Bøyesen P, Eshed I, Gandjbakhch F, Lillegraven S, Bird P, Foltz V, Boonen A, Lassere M, Hermann KG, Anandarajah A, Døhn UM, Freeston J, Peterfy CG, Genant HK, Haavardsholm EA, McQueen FM, Conaghan PG

The Journal of rheumatology.. 2011 September 38 (9):2045-50. Epub 1900 01 01.

Decreased influenza-specific B cell responses in rheumatoid arthritis patients treated with anti-tumor necrosis factor.

Kobie JJ, Zheng B, Bryk P, Barnes M, Ritchlin CT, Tabechian DA, Anandarajah AP, Looney RJ, Thiele RG, Anolik JH, Coca A, Wei C, Rosenberg AF, Feng C, Treanor JJ, Lee FE, Sanz I

Arthritis research & therapy.. 2011 13 (6):R209. Epub 12/16/2011.

Comparative analysis of disease activity measures, use of biologic agents, body mass index, radiographic features, and bone density in psoriatic arthritis and rheumatoid arthritis patients followed in a large U.S. disease registry.

Reddy SM, Anandarajah AP, Fisher MC, Mease PJ, Greenberg JD, Kremer JM, Reed G, Chen R, Messing S, Kaukeinen K, Ritchlin CT

The Journal of rheumatology.. 2010 December 37 (12):2566-72. Epub 09/15/2010.

Erosive osteoarthritis.

Anandarajah A

Discovery medicine.. 2010 May 9 (48):468-77. Epub 1900 01 01.

The diagnosis and treatment of early psoriatic arthritis.

Anandarajah AP, Ritchlin CT,

Nature reviews. Rheumatology.. 2009 November 5 (11):634-41. Epub 10/06/2009.

The OMERACT MRI inflammatory arthritis group: advances and future research priorities.

Conaghan PG, Bird P, McQueen F, Peterfy C, Bøyesen P, Gandjbakhch F, Duer-Jensen A, Haavardsholm EA, Ejbjerg B, Wiell C, Coates L, Hermann KG, O'Connor P, Lassere M, Freeston JE, Anandarajah A, Genant H, Emery P, Ostergaard M

The Journal of rheumatology.. 2009 August 36 (8):1803-5. Epub 1900 01 01.

Role of RANKL in bone diseases.

Anandarajah AP

Trends in endocrinology and metabolism : TEM.. 2009 March 20 (2):88-94. Epub 01/29/2009.

Effect of adalimumab on Magnetic Resonance Imaging features in Patients with Psoriatic Arthritis

Anandarajah, A.P.; Ory, P.; Salonen, D.; Feng, C.; McIllraith, M,; Ritchlin, C.T.

Annals of Rheumatic Disease. 2009; .

Bone loss in the spondyloarthropathies: role of osteoclast, RANKL, RANK and OPG in the spondyloarthropathies.

Anandarajah AP, Schwarz EM

Advances in experimental medicine and biology.. 2009 649 :85-99. Epub 1900 01 01.

The effect of etanercept on osteoclast precursor frequency and enhancing bone marrow edema in patients with psoriatic arthritis.

Anandarajah, A.P.; Totterman, S.; Schwarz, E.M.; Ritchlin, C.T.

Annals of Rheumatic Disease. 2008; 67(3): 296-301.

Advances in the treatment of connective tissue diseases.

Anandarajah, A.P.

Future Rheumatology. 2007; 2: 379-384.

Advances in the treatment of rheumatoid arthritis and the spondyloarthropathies.

Anandarajah, A.P.

Future Rheumatology. 2007; 2: 133-138.

Infliximab in psoriatic arthritis.

Anandarajah, A.P.; Ritchlin, C.T.

Future Rheumatology. 2007; 2.

Anti-RANKL therapy for inflammatory bone disorders: Mechanisms and potential clinical applications.

Anandarajah AP, Schwarz EM

Journal of cellular biochemistry.. 2006 February 197 (2):226-32. Epub 1900 01 01.

Treatment update on spondyloarthropathy.

Anandarajah A, Ritchlin CT

Current opinion in rheumatology.. 2005 May 17 (3):247-56. Epub 1900 01 01.

Dynamic exercises in patients with rheumatoid arthritis.

Anandarajah AP, Schwarz EM

Annals of the rheumatic diseases.. 2004 November 63 (11):1359-61. Epub 1900 01 01.

Treatment update on spondyloarthropathy. From NSAIDs and DMARDs to anti-TNF-alpha agents.

Anandarajah AP, Ritchlin CT

Postgraduate medicine.. 2004 November 116 (5):31-6, 39-40. Epub 1900 01 01.

Pathogenesis of psoriatic arthritis.

Anandarajah AP, Ritchlin CT

Current opinion in rheumatology.. 2004 July 16 (4):338-43. Epub 1900 01 01.

Etanercept in psoriatic arthritis.

Anandarajah AP, Ritchlin CT

Expert opinion on biological therapy.. 2003 February 3 (1):169-77. Epub 1900 01 01.

Role of RANKL in bone metabolism: Clinical Implications.

Anandarajah, A.P.; Schwarz, E.M.

Trends in Endocrinology and Metabolism.

Books

Arthritis; Pathophysiology, prevention and therapeutics. (2011)

Chapter: Pathogenesis of Osteoarthritis:

Authors: Anandarajah AP

Publisher: CRC press 2011

Molecular Mechanisms of Spondyloarthropathies (2008)

Authors: Allen P Anandarajah and Edward Schwarz

Publisher: Landes Company 2008

A Guide to Healthy Pregnancy and Safe Delivery (1993)

Authors: Allen P. Anandarajah

Publisher: Almond Publications, Nigeria 1993

Ratings & Comments

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Ratings

During this visit, did this provider spend enough time with you?

4.9

During this visit, did this provider show respect for what you had to say?

4.9

During this visit, did this provider give you easy to understand information about these health questions or concerns?

4.9

During this visit, did this provider listen carefully to you?

4.9

During this visit, did this provider explain things in a way that was easy to understand?

4.9

Patient Comments

5.0

Dr. Anandarajah is simply the best doctor I could have to care for my RA. I now have lung disease and Dr. A. Is doing a comprehensive effort to develop the best care plan possible. He thoroughly researched all the options for medication. Prior to my visit he contacted other physicians with pulmonary expertise. Dr. A. To get the most Information available regarding my lung condition. He explained everything he presented clearly and answered all of our questions In terms we could understand. He Is simply the best and I am thankful that I have time as my physician.

Feb 25, 2024

5.0

Provider was very helpful with recommendations on how to treat a painful metatarsal foot issue.

Feb 23, 2024

5.0

He is a very compassionate doctor and actually knows how to listen to me. My cardiologist should take a training from Dr. A.!

Feb 15, 2024

5.0

Dr. A is the Best!

Jan 17, 2024

5.0

Dr Anandarajah listens carefully, answers all of my questions and explains things in an easy to understand manner He is very thorough

Dec 15, 2023

5.0

Always professional.

Dec 14, 2023

5.0

I just recommended a friend see Dr. Anandarajah, not only because he is clearly competent, but also because he is a good listener, treats me with respect, discusses my treatment and answers my questions. And after she met with him, she thanked me.

Oct 18, 2023

5.0

Dr. A is the best!!!!!!

Oct 18, 2023

Dr A has always honored my concerns and wishes

Oct 14, 2023

5.0

I love almost all my doctors and Dr A is one of my favorite. He listens carefully, and is the only doc who examines my entire list of medications and we talk about the results, as well as the blood tests. He is also one of the only docs that truly examines my joints, and touches me. Hardly any docs touch anymore.

Sep 28, 2023

5.0

Excellent dr. & person.

Sep 27, 2023

5.0

My care from Dr. Anandarajah has kept my life much more normal.

Sep 25, 2023

5.0

Dr. Anandarajah is very caring compassionate Dr. Who listened to my health issues.

Aug 31, 2023

5.0

Awesome doctor.

Aug 16, 2023

5.0

Dr. A. Has always provided excellent care and is very attentive to my issues and questions.

Aug 12, 2023

5.0

I am so grateful to be under Dr. Anandarajah's care!

Aug 01, 2023

5.0

Very professional, listens, easy to talk to, made me feel better after seeing doctor!!

Jul 21, 2023

5.0

Dr. Anandarajah is great!

Jul 14, 2023

5.0

Always shows concern and listens

Jun 30, 2023

5.0

Doctor Anandarajah is one of the best doctors I have ever had !

May 23, 2023

5.0

All good experience.

May 17, 2023

5.0

Dr. Anandarajah has always considered my questions and recommends best care options given my concerns.

May 16, 2023

5.0

One of the few doctors who really seem to care about my health and answers questions that I might expect other doctors to answer. He does not care that I am 80 years old as other doctors seem to ignore me because of my old age.

May 12, 2023

5.0

My Physician is patient, kind, a GREAT listener, and Clinician!!!!

Feb 23, 2023

5.0

He always listens to what I have to say and helps me understand any medical concerns.

Feb 17, 2023

5.0

HE IS A GOOD LISTENER AND IS WILLING TO DISCUSS ALTERNATIVES WITH ME.

Feb 09, 2023

5.0

I have truly enjoyed Dr. Anandarajah these past few years. He encompasses the ICARE values!!

Feb 03, 2023

5.0

Dr. Anandarajah is probably the kindest, most caring AND knowledgeable Dr. I have seen In all my many years.

Feb 02, 2023

5.0

Dr. Anandarajah is a very caring doctor and zeroes in on all the aspects of my rheumatoid arthritis.

Jan 28, 2023

5.0

Dr. A has provided me with medical and personal guidance with which to stave off pain and enables me to pursue the outdoor activities I enjoy, to include golf and hunting.

Jan 27, 2023

5.0

Showed concern. Very polite. Covered all my concerns.

Dec 14, 2022

5.0

Dr. Anandarajah is a wonderful doctor. He's smart, caring and always has good advice to make me more healthy.

Oct 19, 2022

3.0

He told me I should be happy to leave the office with no prognosis when I became tearful. Once blood work was completed and showed the opposite of what he explained in the office no explanation was given. No change in plan made. I now live in constant pain and someday I am unable to care for myself or work..... It seemed like he didn't care. He just wanted me out if his office.

Oct 11, 2022

5.0

Dr is always very patient and listens and advises

Sep 29, 2022

5.0

Awesome physician, very thoughtful, helpful, knowledgeable. Extremely polite but not at all stand offish. Great experience

Sep 23, 2022

5.0

He is the best.

Aug 01, 2022

5.0

Doctor Anandarajah is one of the nicest doctors I've ever met, he's so thorough so kind and always really wants to know how you feel. He always shows so much concern and compassion he's one of the best doctors I've ever had thank you Dr. Anandarajah being so kind and thorough and concern

Jul 20, 2022

5.0

Dr. Anandarajah is an extraordinary physician. He's what every physician should strive to be!

Jun 09, 2022

5.0

My blood pressure was high and both my doctor and nurse showed the necessary concern but calmed my concerns, waited twenty minutes then took it again.

Jun 01, 2022

5.0

He makes eye contact. He listens. He knows what he's talking about. I trust his opinions/thoughts.

May 16, 2022

5.0

I recommended Dr. A. To someone just the other day!

May 16, 2022

5.0

Wonderful physician

Apr 27, 2022

5.0

The provider was concerned not only about the quality of the care/treatment but also the cost of the options presented.

Apr 19, 2022

5.0

Excellent!

Apr 18, 2022

5.0

Dr Anandarajah treats you like you are his only patient

Apr 08, 2022

5.0

Dr. Anandarajah and Dr. House listened carefully, explained things well and gave me a thourough examination

Apr 07, 2022

1.0

The doctor walked into the room and complained that he didn't know why I had been sent there. I have an elevated marker for Lupus and several symptoms and haven't fully recovered from covid. [...] I felt very disrespected at that appointment [...]

Mar 30, 2022

5.0

Always a good experience with doctor and staff.

Mar 23, 2022

5.0

Dr. Anandarajah always makes me feel at ease and shows and explains the results of my blood tests. He asks me questions and always leaves time to answer any questions or concerns I may have.

Mar 22, 2022

5.0

Being my new rheumatologist I liked him. He caught things on prior tests and recommended treatment with follow up blood work.

Mar 09, 2022

5.0

Dr. Anandarajah is amazing. He's one of the most caring physicians I have ever been to. A real strong star!

Feb 21, 2022

Dr. Anandarajah has excellent listening skills. Very good with communication, much much better than most doctors I see.

Feb 10, 2022