Brian J. Blyth, M.D.

Brian J. Blyth, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 655
Rochester, NY 14642

Office: (585) 275-1198

Research Bio

The research efforts of the Blyth laboratory focus on traumatic brain injury. The overarching goal of our laboratory is to reduce the morbidity and mortality associated with traumatic brain injury. To accomplish this goal we rely on a translational approach: both clinical and basic studies are used to identify and solve relevant research questions that might lead to improved therapeutics for this disease. Ultimately, promising therapies are tested for efficacy through clinical trials. Laboratory resources include a repository of patient samples collected through a multicenter research network that includes six medical centers located throughout upstate New York with 300,000 patient visits per year.

Data and clinical samples collected through this network are housed at a central repository located within the laboratory. Physically, the laboratory consists of state of the art bench research facilities within the Center for Neural Development and Disease at the University of Rochester Medical Center. We utilize patient based studies as well as cell culture and animal models of disease. Several mouse and rat models of traumatic brain injury are utilized. Relevant questions are identified through studies of large numbers of human patients and examined in detail in animal models. Mechanistic insights gleaned through this approach may then allow for novel therapeutics that can then be developed for clinical trials.

Awards & Honors (Local)

Army Commendation Medal    | US Army | Bagram Air Field, Afghanistan 2008 - 2008
Army Commendation Medal    | US Army | Fort Lewis, Washington 2006
The Course in Scientific Management | The Burroughs Welcome Fund and Howard Hughes Medical Institute 2005
Emergency Medicine Faculty Teaching Award | University of Rochester Medical Center 2004
Army Commendation Medal    | US Army | Doha, Kuwait 2003
Emergency Medicine Resident Teaching Award | University of Rochester Medical Center | Rochester, NY 2002
Excellence in Emergency Medicine Award for Graduating Medical Students | Society for Academic Emergency Medicine 1999
Howard Hughes Medical Institute Fellowship Award | University of Pittsburgh Medical Center 1997 - 1998
University of Rochester Medical Center Departmental Research Fellow 2002-2003 Department of Emergency Medicine Rochester, NY

Patents

Novel Serum Markers for the Diagnosis of Concussions and Mild Traumatic Brain Injury

United States Serial NO.: 13/430,365
Filed Date: March 26, 2012
Title: Method of Diagnosing Mild Traumatic Brain Injury
Invented by: Bryan Blyth, Jeffrey Bazarian
Apo A1 Marker

United States Serial NO.: 14/365,550
Filed Date: December 11, 2012
Title: Method of Diagnosing Mild Traumatic Brain Injury
Invented by: Bryan Blyth, Jeffrey Bazarian

Recent Journal Articles

Showing the 5 most recent journal articles. 10 available »

2014
Kiechle K, Bazarian JJ, Merchant-Borna K, Stoecklein V, Rozen E, Blyth B, Huang JH, Dayawansa S, Kanz K, Biberthaler P. "Subject-specific increases in serum S-100B distinguish sports-related concussion from sports-related exertion." PloS one. 2014 9(1):e84977. Epub 2014 Jan 08.
2013 Oct 15
Bazarian JJ, Blyth B, He H, Mookerjee S, Jones C, Kiechle K, Moynihan R, Wojcik S, Grant WD, Secreti L, Triner W, Moscati R, Leinhart A, Ellis G, Khan J. "Classification accuracy of serum Apo A-I and S100B for the diagnosis of mild traumatic brain injury and prediction of abnormal initial head computed tomography scan." Journal of neurotrauma. 2013 Oct 15; 30(20):1747-54. Epub 2013 Aug 24.
2011
Blyth B, Farahvar A, He H, Nayak A, Yang C, Shaw G, Bazarian JJ. "Elevated serum ubiquitin carboxy-terminal hydrolase L1 is associated with abnormal blood-brain barrier function after traumatic brain injury." Journal of neurotrauma. 2011 28(12):2453-62. Epub 2011 Aug 08.
2010 Aug
Blyth BJ, Bazarian JJ. "Traumatic alterations in consciousness: traumatic brain injury." Emergency medicine clinics of North America. 2010 Aug; 28(3):571-94.
2010 Mar
Bazarian JJ, Blyth B, Mookerjee S, He H, McDermott M. "Sex differences in outcome after mild traumatic brain injury." Journal of neurotrauma. 2010 Mar; 27(3):527-39.

Specialties

Emergency Medicine - American Board of Emergency Medicine

Education

MD | Medicine | Univ Pittsburgh Sch Medicine1999
BA | Behavioral Science, Other | University of Rochester1989

Post-Doctoral Training & Residency

Residency in Emergency Medicine at Strong Memorial Hospital- GME Office07/01/2000 - 06/30/2002
Internship in Emergency Medicine at Strong Memorial Hospital- GME Office07/01/1999 - 06/01/2000