Deborah A. Slechta, Ph.D.

Deborah A. Slechta, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box EHSC
Rochester, NY 14642

Office: (585) 275-7060
Fax: (585) 256-2591

Research Bio

Dr. Deborah Cory-Slechta became a faculty member at the University of Rochester Medical School (URMC) in 1982. She went on to become Chair of its Department of Environmental Medicine and Director of the NIEHS Environmental Health Sciences Center in 1998. She served as Dean for Research at the University of Rochester Medical School from 2000-2002. She then moved to NJ to become Director of the Environmental and Occupational Health Sciences Institute (EOHSI) and Chair of the Department of Environmental and Community Medicine at the UMDNJ-Robert Wood Johnson Medical School from 2003-2007, before returning to URMC as Professor in Environmental Medicine and Pediatrics.

Dr. Cory-Slechta has served on numerous national review and advisory panels of the National Institutes of Health, the National Institute of Environmental Health Sciences, the Food and Drug Administration, the National Center for Toxicological Research, the Environmental Protection Agency, the National Academy of Sciences, the Institute of Medicine, and the Agency for Toxic Substances and Disease Registry, Centers for Disease Control. In addition, Dr. Cory-Slechta has served on the editorial boards of the journals Neurotoxicology, Toxicology, Toxicological Sciences, Fundamental and Applied Toxicology, Neurotoxicology and Teratology, and American Journal of Mental Retardation. She has held the elected positions of President of the Neurotoxicology Specialty Section of the Society of Toxicology, President of the Behavioral Toxicology Society, and been named a Fellow of the American Psychological Association. Her research has focused largely on the relationships between brain neurotransmitter systems and children's neurodevelopment, and how such relationships are altered by exposures to environmental toxicants, including the role played by environmental neurotoxicant exposures in developmental disabilities and neurodegenerative diseases. These research efforts have resulted in over 150 papers and book chapters to date.
Dr. Cory-Slechta is the co-director of the Behavioral Sciences Facility Core and director of the Animal Behavior Core which provides consultation and assistance to any investigators seeking to develop or implement a behavioral project aiming advance translational neurobehavioral research and enhance our understanding of human disease. The Behavioral Sciences Facility Core's mission is to advance the field of behavioral science by providing high quality services to scientists performing behavioral studies. Our ability to perform both animal and human behavioral testing allows us to work bi-directionally, applying lessons learned from animal work to human studies and vice versa. For this reason, our facility works on the cutting edge of translational behavioral research.
Dr. Cory-Slechta also directs the K12 WHEEL program at URMC. The Women's Health and the Environment Over the Entire Lifespan program provides career development for promising scientists interested in pursuing a research career in women's environmental health. Environmental exposures can affect males and females differently, often by acting on hormonal systems. These exposures appear to have greatest impact during critical periods across the lifespan (including prenatal, perinatal, childhood, mid-life and late-life).

Awards & Honors (Local)

Honoree, Fourth Annual Women in Science Symposium, Joint Programs of University of Medicine and Dentistry of New Jersey and Rutgers University, sponsored by The Environmental and Occupational Health Sciences Institute, Douglass College Project for Rutgers Women in Math, Science and Engineering, Joint Graduate Program in Toxicology, and the Joint Postdoctoral Program in Exposure Assessment, Piscataway, NJ 2001
National Institute of Environmental Health Sciences New Investigator Award 1982 - 1985
National Research Service Award Postdoctoral Fellowship 1979 - 1982
Alpha Lambda Delta, honorary sorority 1969

Recent Journal Articles

Showing the 5 most recent journal articles. 53 available »

2014 Sep
Allen JL, Liu X, Pelkowski S, Palmer B, Conrad K, Oberdörster G, Weston D, Mayer-Pröschel M, Cory-Slechta DA. "Early postnatal exposure to ultrafine particulate matter air pollution: persistent ventriculomegaly, neurochemical disruption, and glial activation preferentially in male mice." Environmental health perspectives. 2014 Sep; 122(9):939-45. Epub 2014 May 22.
2014 Sep
Weston HI, Weston DD, Allen JL, Cory-Slechta DA. "Sex-dependent impacts of low-level lead exposure and prenatal stress on impulsive choice behavior and associated biochemical and neurochemical manifestations." Neurotoxicology. 2014 Sep; 44:169-83. Epub 2014 Jul 07.
2014 Mar
Allen JL, Liu X, Weston D, Conrad K, Oberdörster G, Cory-Slechta DA. "Consequences of developmental exposure to concentrated ambient ultrafine particle air pollution combined with the adult paraquat and maneb model of the Parkinson's disease phenotype in male mice." Neurotoxicology. 2014 Mar; 41:80-8. Epub 2014 Jan 30.
2014 Mar
Weston HI, Sobolewski M, Allen JL, Weston D, Conrad K, Pelkowski S, Watson GE, Zareba G, Cory-Slechta DA. "Sex-dependent and non-monotonic enhancement and unmasking of methylmercury neurotoxicity by prenatal stress." Neurotoxicology. 2014 Mar; 41:123-40. Epub 2014 Feb 03.
2014 Jan 17
Kobrosly RW, van Wijngaarden E, Seplaki CL, Cory-Slechta DA, Moynihan J. "Depressive symptoms are associated with allostatic load among community-dwelling older adults." Physiology & behavior. 2014 Jan 17; 123:223-30.

Current Appointments

Professor - Department of Environmental Medicine (SMD) - Primary

Education

PhD | Psychology | Univ Minnesota-Minneapolis1977
MA | Psychology | Western Michigan Univ1972
BS | Psychology | Western Michigan Univ1971

Post-Doctoral Training & Residency

Postdoctoral Fellow, Behavioral Toxicology and Pharmacology, Department of Radiation Biology and Biophysics, University of Rochester. Advisors: Drs. Bernard Weiss and Victor G. Laties 1982
Junior Staff Fellow, National Center for Toxicological Research, Jefferson, AR 1979