Deborah A. Slechta, Ph.D.

Deborah A. Slechta, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box EHSC
Rochester, NY 14642

Office: (585) 275-7060
Fax: (585) 256-2591

Journal Articles

Showing all 53 journal articles available.

2014 Jul 7
Weston HI, Weston DD, Allen JL, Cory-Slechta DA. "Sex-dependent impacts of low-level lead exposure and prenatal stress on impulsive choice behavior and associated biochemical and neurochemical manifestations." Neurotoxicology.. 2014 Jul 7; 44C:169-183. Epub 2014 Jul 07.
2014 Jun 5
Allen JL, Liu X, Pelkowski S, Palmer B, Conrad K, Oberdörster G, Weston D, Mayer-Pröschel M, Cory-Slechta DA. "Early Postnatal Exposure to Ultrafine Particulate Matter Air Pollution: Persistent Ventriculomegaly, Neurochemical Disruption, and Glial Activation Preferentially in Male Mice." Environmental health perspectives.. 2014 Jun 5; Epub 2014 Jun 05.
2014 Mar
Allen JL, Liu X, Weston D, Conrad K, Oberdörster G, Cory-Slechta DA. "Consequences of developmental exposure to concentrated ambient ultrafine particle air pollution combined with the adult paraquat and maneb model of the Parkinson's disease phenotype in male mice." Neurotoxicology.. 2014 Mar; 41:80-8. Epub 2014 Jan 30.
2014 Mar
Weston HI, Sobolewski M, Allen JL, Weston D, Conrad K, Pelkowski S, Watson GE, Zareba G, Cory-Slechta DA. "Sex-dependent and non-monotonic enhancement and unmasking of methylmercury neurotoxicity by prenatal stress." Neurotoxicology.. 2014 Mar; 41:123-40. Epub 2014 Feb 03.
2014 Jan 17
Kobrosly RW, van Wijngaarden E, Seplaki CL, Cory-Slechta DA, Moynihan J. "Depressive symptoms are associated with allostatic load among community-dwelling older adults." Physiology & behavior.. 2014 Jan 17; 123:223-30.
2013 Aug
Nkhoma OW, Duffy ME, Cory-Slechta DA, Davidson PW, McSorley EM, Strain JJ, O'Brien GM. "Early-stage primary school children attending a school in the Malawian School Feeding Program (SFP) have better reversal learning and lean muscle mass growth than those attending a non-SFP school." The Journal of nutrition.. 2013 Aug; 143(8):1324-30. Epub 2013 Jun 26.
2013 Jul
Kobrosly RW, Seplaki CL, Cory-Slechta DA, Moynihan J, van Wijngaarden E. "Multisystem physiological dysfunction is associated with depressive symptoms in a population-based sample of older adults." International journal of geriatric psychiatry.. 2013 Jul; 28(7):718-27. Epub 2012 Sep 07.
2013 Jun
Lyngdoh T, Viswanathan B, Kobrosly R, van Wijngaarden E, Huber B, Davidson PW, Cory-Slechta DA, Strain S, Myers GJ, Bovet P. "Blood pressure and cognitive function: a prospective analysis among adolescents in Seychelles." Journal of hypertension.. 2013 Jun; 31(6):1175-82.
2013 Jun
Bellinger DC, Burger J, Cade TJ, Cory-Slechta DA, Finkelstein M, Hu H, Kosnett M, Landrigan PJ, Lanphear B, Pokras MA, Redig PT, Rideout BA, Silbergeld E, Wright R, Smith DR. "Health risks from lead-based ammunition in the environment." Environmental health perspectives.. 2013 Jun; 121(6):A178-9.
2013 May
Nkhoma OW, Duffy ME, Davidson PW, Cory-Slechta DA, McSorley EM, Strain JJ, O'Brien GM. "Nutritional and cognitive status of entry-level primary school children in Zomba, rural Malawi." International journal of food sciences and nutrition.. 2013 May; 64(3):282-91. Epub 2012 Nov 23.
2013 Apr
Cory-Slechta DA, Weston D, Liu S, Allen JL. "Brain hemispheric differences in the neurochemical effects of lead, prenatal stress, and the combination and their amelioration by behavioral experience." Toxicological sciences : an official journal of the Society of Toxicology.. 2013 Apr; 132(2):419-30. Epub 2013 Jan 28.
2013 Jan
Cory-Slechta DA, Merchant-Borna K, Allen JL, Liu S, Weston D, Conrad K. "Variations in the nature of behavioral experience can differentially alter the consequences of developmental exposures to lead, prenatal stress, and the combination." Toxicological sciences : an official journal of the Society of Toxicology.. 2013 Jan; 131(1):194-205. Epub 2012 Aug 28.
2013 Jan
Allen JL, Conrad K, Oberdörster G, Sleezer B, Cory-Slechta DA. "Developmental exposure to concentrated ambient particles and preference for immediate reward in mice." Environmental health perspectives.. 2013 Jan; 121(1):32-8. Epub 2012 Oct 11.
2013 Jan
Beier EE, Maher JR, Sheu TJ, Cory-Slechta DA, Berger AJ, Zuscik MJ, Puzas JE. "Heavy metal lead exposure, osteoporotic-like phenotype in an animal model, and depression of Wnt signaling." Environmental health perspectives.. 2013 Jan; 121(1):97-104. Epub 2012 Oct 19.
2012 Nov
Strain JJ, Davidson PW, Thurston SW, Harrington D, Mulhern MS, McAfee AJ, van Wijngaarden E, Shamlaye CF, Henderson J, Watson GE, Zareba G, Cory-Slechta DA, Lynch M, Wallace JM, McSorley EM, Bonham MP, Stokes-Riner A, Sloane-Reeves J, Janciuras J, Wong R, Clarkson TW, Myers GJ. "Maternal PUFA status but not prenatal methylmercury exposure is associated with children's language functions at age five years in the Seychelles." The Journal of nutrition.. 2012 Nov; 142(11):1943-9. Epub 2012 Sep 26.
2012 Oct
Block ML, Elder A, Auten RL, Bilbo SD, Chen H, Chen JC, Cory-Slechta DA, Costa D, Diaz-Sanchez D, Dorman DC, Gold DR, Gray K, Jeng HA, Kaufman JD, Kleinman MT, Kirshner A, Lawler C, Miller DS, Nadadur SS, Ritz B, Semmens EO, Tonelli LH, Veronesi B, Wright RO, Wright RJ. "The outdoor air pollution and brain health workshop." Neurotoxicology.. 2012 Oct; 33(5):972-84. Epub 2012 Sep 05.
2012 Feb
Lee DW, Notter SA, Thiruchelvam M, Dever DP, Fitzpatrick R, Kostyniak PJ, Cory-Slechta DA, Opanashuk LA. "Subchronic polychlorinated biphenyl (Aroclor 1254) exposure produces oxidative damage and neuronal death of ventral midbrain dopaminergic systems." Toxicological sciences : an official journal of the Society of Toxicology.. 2012 Feb; 125(2):496-508. Epub 2011 Nov 17.
2012 Feb
Fortin MC, Cory-Slechta DA, Ohman-Strickland P, Nwankwo C, Yanger TS, Todd AC, Moynihan J, Walton J, Brooks A, Fiedler N. "Increased lead biomarker levels are associated with changes in hormonal response to stress in occupationally exposed male participants." Environmental health perspectives.. 2012 Feb; 120(2):278-83. Epub 2011 Nov 23.
2011 Jan
van Wijngaarden E, Winters PC, Cory-Slechta DA. "Blood lead levels in relation to cognitive function in older U.S. adults." Neurotoxicology.. 2011 Jan; 32(1):110-5. Epub 2010 Nov 17.
2011
Kobrosly RW, van Wijngaarden E, Galea S, Cory-Slechta DA, Love T, Hong C, Shamlaye CF, Davidson PW. "Socioeconomic position and cognitive function in the Seychelles: a life course analysis." Neuroepidemiology. 2011 36(3):162-8. Epub 2011 Apr 20.
2011
Davidson PW, Cory-Slechta DA, Thurston SW, Huang LS, Shamlaye CF, Gunzler D, Watson G, van Wijngaarden E, Zareba G, Klein JD, Clarkson TW, Strain JJ, Myers GJ. "Fish consumption and prenatal methylmercury exposure: cognitive and behavioral outcomes in the main cohort at 17 years from the Seychelles child development study." Neurotoxicology.. 2011 32(6):711-7. Epub 2011 Aug 25.
2010 Oct
Cory-Slechta DA, Stern S, Weston D, Allen JL, Liu S. "Enhanced learning deficits in female rats following lifetime pb exposure combined with prenatal stress." Toxicological sciences : an official journal of the Society of Toxicology.. 2010 Oct; 117(2):427-38. Epub 2010 Jul 16.
2009 Jul
van Wijngaarden E, Campbell JR, Cory-Slechta DA. "Bone lead levels are associated with measures of memory impairment in older adults." Neurotoxicology.. 2009 Jul; 30(4):572-80. Epub 2009 May 27.
2008 Jun 25
Lanphear BP, Hornung RW, Khoury J, Dietrich KN, Cory-Slechta DA, Canfield RL. "The conundrum of unmeasured confounding: Comment on: "Can some of the detrimental neurodevelopmental effects attributed to lead be due to pesticides? by Brian Gulson"." The Science of the total environment.. 2008 Jun 25; 396(2-3):196-200. Epub 2008 Mar 07.
2008 May
Cory-Slechta DA, Thiruchelvam M, Di Monte DA. "Letter regarding: "Paraquat: the red herring of Parkinson's disease research"." Toxicological sciences : an official journal of the Society of Toxicology.. 2008 May; 103(1):215-6; author reply 217-8. Epub 2007 Dec 27.
2008 Feb
Cory-Slechta DA, Virgolini MB, Rossi-George A, Thiruchelvam M, Lisek R, Weston D. "Lifetime consequences of combined maternal lead and stress." Basic & clinical pharmacology & toxicology.. 2008 Feb; 102(2):218-27.
2008 Feb
Jusko TA, Henderson CR, Lanphear BP, Cory-Slechta DA, Parsons PJ, Canfield RL. "Blood lead concentrations < 10 microg/dL and child intelligence at 6 years of age." Environmental health perspectives.. 2008 Feb; 116(2):243-8.
2007 Aug 1
Froehlich TE, Lanphear BP, Dietrich KN, Cory-Slechta DA, Wang N, Kahn RS. "Interactive effects of a DRD4 polymorphism, lead, and sex on executive functions in children." Biological psychiatry.. 2007 Aug 1; 62(3):243-9. Epub 2007 Jan 17.
2007 Mar 16
Gray JP, Heck DE, Mishin V, Smith PJ, Hong JY, Thiruchelvam M, Cory-Slechta DA, Laskin DL, Laskin JD. "Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase." The Journal of biological chemistry.. 2007 Mar 16; 282(11):7939-49. Epub 2007 Jan 17.
2007
Barlow BK, Cory-Slechta DA, Richfield EK, Thiruchelvam M. "The gestational environment and Parkinson's disease: evidence for neurodevelopmental origins of a neurodegenerative disorder." Reproductive toxicology.. 2007 23(3):457-70. Epub 2007 Feb 06.
2006
Davidson PW, Weiss B, Beck C, Cory-Slechta DA, Orlando M, Loiselle D, Young EC, Sloane-Reeves J, Myers GJ. "Development and validation of a test battery to assess subtle neurodevelopmental differences in children." Neurotoxicology.. 2006 27(6):951-69. Epub 2006 Apr 28.
2005 Oct
Virgolini MB, Chen K, Weston DD, Bauter MR, Cory-Slechta DA. "Interactions of chronic lead exposure and intermittent stress: consequences for brain catecholamine systems and associated behaviors and HPA axis function." Toxicological sciences : an official journal of the Society of Toxicology.. 2005 Oct; 87(2):469-82. Epub 2005 Jul 27.
2005 Sep
Cory-Slechta DA, Thiruchelvam M, Barlow BK, Richfield EK. "Developmental pesticide models of the Parkinson disease phenotype." Environmental health perspectives.. 2005 Sep; 113(9):1263-70.
2005 Aug
Cory-Slechta DA. "Studying toxicants as single chemicals: does this strategy adequately identify neurotoxic risk?" Neurotoxicology.. 2005 Aug; 26(4):491-510.
2005 Jun 10
Thiruchelvam M, Prokopenko O, Cory-Slechta DA, Richfield EK, Buckley B, Mirochnitchenko O. "Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype." The Journal of biological chemistry.. 2005 Jun 10; 280(23):22530-9. Epub 2005 Apr 11.
2005 Jun
Rodriguez VM, Thiruchelvam M, Cory-Slechta DA. "Sustained exposure to the widely used herbicide atrazine: altered function and loss of neurons in brain monoamine systems." Environmental health perspectives.. 2005 Jun; 113(6):708-15.
2005 Jun
Carmouche JJ, Puzas JE, Zhang X, Tiyapatanaputi P, Cory-Slechta DA, Gelein R, Zuscik M, Rosier RN, Boyce BF, O'Keefe RJ, Schwarz EM. "Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency." Environmental health perspectives.. 2005 Jun; 113(6):749-55.
2005 Mar
Cory-Slechta DA, Thiruchelvam M, Richfield EK, Barlow BK, Brooks AI. "Developmental pesticide exposures and the Parkinson's disease phenotype." Birth defects research. Part A, Clinical and molecular teratology.. 2005 Mar; 73(3):136-9.
2005 Jan
Barlow BK, Lee DW, Cory-Slechta DA, Opanashuk LA. "Modulation of antioxidant defense systems by the environmental pesticide maneb in dopaminergic cells." Neurotoxicology.. 2005 Jan; 26(1):63-75.
2004 Oct 1
Reeves R, Thiruchelvam M, Richfield EK, Cory-Slechta DA. "The effect of developmental exposure to the fungicide triadimefon on behavioral sensitization to triadimefon during adulthood." Toxicology and applied pharmacology.. 2004 Oct 1; 200(1):54-63.
2004 May
Cory-Slechta DA, Virgolini MB, Thiruchelvam M, Weston DD, Bauter MR. "Maternal stress modulates the effects of developmental lead exposure." Environmental health perspectives.. 2004 May; 112(6):717-30.
2004
Canfield RL, Gendle MH, Cory-Slechta DA. "Impaired neuropsychological functioning in lead-exposed children." Developmental neuropsychology.. 2004 26(1):513-40.
2004
Barlow BK, Richfield EK, Cory-Slechta DA, Thiruchelvam M. "A fetal risk factor for Parkinson's disease." Developmental neuroscience.. 2004 26(1):11-23.
2003 Sep
Reeves R, Thiruchelvam M, Richfield EK, Cory-Slechta DA. "Behavioral sensitization and long-term neurochemical alterations associated with the fungicide triadimefon." Pharmacology, biochemistry, and behavior.. 2003 Sep; 76(2):315-26.
2003 Aug
Thiruchelvam M, McCormack A, Richfield EK, Baggs RB, Tank AW, Di Monte DA, Cory-Slechta DA. "Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype." The European journal of neuroscience.. 2003 Aug; 18(3):589-600.
2003 May
Barlow BK, Thiruchelvam MJ, Bennice L, Cory-Slechta DA, Ballatori N, Richfield EK. "Increased synaptosomal dopamine content and brain concentration of paraquat produced by selective dithiocarbamates." Journal of neurochemistry.. 2003 May; 85(4):1075-86.
2003 Apr 17
Canfield RL, Henderson CR, Cory-Slechta DA, Cox C, Jusko TA, Lanphear BP. "Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter." The New England journal of medicine.. 2003 Apr 17; 348(16):1517-26.
2003 Mar
Cory-Slechta DA. "Lead-induced impairments in complex cognitive function: offerings from experimental studies." Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence.. 2003 Mar; 9(1):54-75.
2002 Oct
Thiruchelvam M, Richfield EK, Goodman BM, Baggs RB, Cory-Slechta DA. "Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype." Neurotoxicology.. 2002 Oct; 23(4-5):621-33.
2002 Sep
Cory-Slechta DA, Brockel BJ, O'Mara DJ. "Lead exposure and dorsomedial striatum mediation of fixed interval schedule-controlled behavior." Neurotoxicology.. 2002 Sep; 23(3):313-27.
2002 Jul
McCormack AL, Thiruchelvam M, Manning-Bog AB, Thiffault C, Langston JW, Cory-Slechta DA, Di Monte DA. "Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat." Neurobiology of disease.. 2002 Jul; 10(2):119-27.
2002 May
Richfield EK, Thiruchelvam MJ, Cory-Slechta DA, Wuertzer C, Gainetdinov RR, Caron MG, Di Monte DA, Federoff HJ. "Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice." Experimental neurology.. 2002 May; 175(1):35-48.
2002 Apr 30
Brooks AI, Stein CS, Hughes SM, Heth J, McCray PM, Sauter SL, Johnston JC, Cory-Slechta DA, Federoff HJ, Davidson BL. "Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors." Proceedings of the National Academy of Sciences of the United States of America.. 2002 Apr 30; 99(9):6216-21. Epub 2002 Apr 16.

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