Charles A. Thornton, M.D.

Charles A. Thornton, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 645
Rochester, NY 14642

Office: (585) 275-2542
Fax: (585) 276-1947
Administrative: (585) 275-2542
Lab: (585) 275-7108

Journal Articles

Showing all 121 journal articles available.

2014 Aug
Thornton CA. "Myotonic Dystrophy." Neurologic clinics.. 2014 Aug; 32(3):705-719. Epub 2014 Jun 06.
2014 Jun
Heatwole C, Bode R, Johnson N, Dekdebrun J, Dilek N, Heatwole M, Hilbert JE, Luebbe E, Martens W, McDermott MP, Rothrock N, Thornton C, Vickrey BG, Victorson D, Moxley R. "Myotonic Dystrophy Health Index: initial evaluation of a disease-specific outcome measure." Muscle & nerve.. 2014 Jun; 49(6):906-14.
2014
Hoskins JW, Ofori LO, Chen CZ, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan JJ, Zheng W, Austin CP, Disney MD, Miller BL, Thornton CA. "Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects." Nucleic acids research.. 2014 42(10):6591-602. Epub 2014 May 05.
2013 Feb
Sobczak K, Wheeler TM, Wang W, Thornton CA. "RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy." Molecular therapy : the journal of the American Society of Gene Therapy.. 2013 Feb; 21(2):380-7. Epub 2012 Nov 27.
2013
Childs-Disney JL, Stepniak-Konieczna E, Tran T, Yildirim I, Park H, Chen CZ, Hoskins J, Southall N, Marugan JJ, Patnaik S, Zheng W, Austin CP, Schatz GC, Sobczak K, Thornton CA, Disney MD. "Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules." Nature communications. 2013 4:2044.
2013
Nakamori M, Sobczak K, Puwanant A, Welle S, Eichinger K, Pandya S, Dekdebrun J, Heatwole CR, McDermott MP, Chen T, Cline M, Tawil R, Osborne RJ, Wheeler TM, Swanson M, Moxley RT, Thornton CA. "Splicing biomarkers of disease severity in myotonic dystrophy." Annals of neurology.. 2013 74(6):862-72.
2013
Axford MM, Wang YH, Nakamori M, Zannis-Hadjopoulos M, Thornton CA, Pearson CE. "Detection of slipped-DNAs at the trinucleotide repeats of the myotonic dystrophy type I disease locus in patient tissues." PLoS genetics.. 2013 9(12):e1003866. Epub 2013 Dec 19.
2012 Aug 2
Wheeler TM, Leger AJ, Pandey SK, Macleod AR, Nakamori M, Cheng SH, Wentworth BM, Bennett CF, Thornton CA. "Targeting nuclear RNA for in vivo correction of myotonic dystrophy." Nature.. 2012 Aug 2; 488(7409):111-5.
2012 Jul 24
Heatwole C, Bode R, Johnson N, Quinn C, Martens W, McDermott MP, Rothrock N, Thornton C, Vickrey B, Victorson D, Moxley R. "Patient-reported impact of symptoms in myotonic dystrophy type 1 (PRISM-1)." Neurology.. 2012 Jul 24; 79(4):348-57. Epub 2012 Jul 11.
2012 Jul
Ofori LO, Hoskins J, Nakamori M, Thornton CA, Miller BL. "From dynamic combinatorial 'hit' to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy." Nucleic acids research.. 2012 Jul; 40(13):6380-90. Epub 2012 Apr 06.
2012 Mar 15
Tang ZZ, Yarotskyy V, Wei L, Sobczak K, Nakamori M, Eichinger K, Moxley RT, Dirksen RT, Thornton CA. "Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel." Human molecular genetics.. 2012 Mar 15; 21(6):1312-24. Epub 2011 Dec 02.
2012 Mar
Hilbert JE, Kissel JT, Luebbe EA, Martens WB, McDermott MP, Sanders DB, Tawil R, Thornton CA, Moxley RT, . "If you build a rare disease registry, will they enroll and will they use it? Methods and data from the National Registry of Myotonic Dystrophy (DM) and Facioscapulohumeral Muscular Dystrophy (FSHD)." Contemporary clinical trials.. 2012 Mar; 33(2):302-11. Epub 2011 Nov 26.
2012 Jan
Mankodi A, Wheeler TM, Shetty R, Salceies KM, Becher MW, Thornton CA. "Progressive myopathy in an inducible mouse model of oculopharyngeal muscular dystrophy." Neurobiology of disease.. 2012 Jan; 45(1):539-46. Epub 2011 Sep 21.
2011 Mar
Lueck JD, Rossi AE, Thornton CA, Campbell KP, Dirksen RT. "Response to the letter: "On the localization of ClC-1 in skeletal muscle fibers"." The Journal of general physiology. 2011 Mar; 137(3):331-3.
2011 Feb 1
Nakamori M, Pearson CE, Thornton CA. "Bidirectional transcription stimulates expansion and contraction of expanded (CTG)*(CAG) repeats." Human molecular genetics.. 2011 Feb 1; 20(3):580-8. Epub 2010 Nov 18.
2011 Jan
Heatwole CR, Eichinger KJ, Friedman DI, Hilbert JE, Jackson CE, Logigian EL, Martens WB, McDermott MP, Pandya SK, Quinn C, Smirnow AM, Thornton CA, Moxley RT. "Open-label trial of recombinant human insulin-like growth factor 1/recombinant human insulin-like growth factor binding protein 3 in myotonic dystrophy type 1." Archives of neurology.. 2011 Jan; 68(1):37-44. Epub 2010 Sep 13.
2011
Nakamori M, Gourdon G, Thornton CA. "Stabilization of expanded (CTG)•(CAG) repeats by antisense oligonucleotides." Molecular therapy : the journal of the American Society of Gene Therapy.. 2011 19(12):2222-7. Epub 2011 Oct 04.
2010 Jul
Nakamori M, Thornton C. "Epigenetic changes and non-coding expanded repeats." Neurobiology of disease.. 2010 Jul; 39(1):21-7. Epub 2010 Feb 18.
2010 May 4
Logigian EL, Martens WB, Moxley RT, McDermott MP, Dilek N, Wiegner AW, Pearson AT, Barbieri CA, Annis CL, Thornton CA, Moxley RT. "Mexiletine is an effective antimyotonia treatment in myotonic dystrophy type 1." Neurology.. 2010 May 4; 74(18):1441-8.
2010 Feb
Logigian EL, Twydell P, Dilek N, Martens WB, Quinn C, Wiegner AW, Heatwole CR, Thornton CA, Moxley RT. "Evoked myotonia can be "dialed-up" by increasing stimulus train length in myotonic dystrophy type 1." Muscle & nerve.. 2010 Feb; 41(2):191-6.
2010
Lueck JD, Rossi AE, Thornton CA, Campbell KP, Dirksen RT. "Sarcolemmal-restricted localization of functional ClC-1 channels in mouse skeletal muscle." The Journal of general physiology. 2010 136(6):597-613. Epub 2010 Nov 15.
2009 Nov
Nakamori M, Sobczak K, Moxley RT, Thornton CA. "Scaled-down genetic analysis of myotonic dystrophy type 1 and type 2." Neuromuscular disorders : NMD.. 2009 Nov; 19(11):759-62. Epub 2009 Aug 26.
2009 Oct
Welle S, Burgess K, Thornton CA, Tawil R. "Relation between extent of myostatin depletion and muscle growth in mature mice." American journal of physiology. Endocrinology and metabolism.. 2009 Oct; 297(4):E935-40. Epub 2009 Aug 04.
2009 Jul 22
Pushechnikov A, Lee MM, Childs-Disney JL, Sobczak K, French JM, Thornton CA, Disney MD. "Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3." Journal of the American Chemical Society.. 2009 Jul 22; 131(28):9767-79.
2009 Jul 17
Wheeler TM, Sobczak K, Lueck JD, Osborne RJ, Lin X, Dirksen RT, Thornton CA. "Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA." Science.. 2009 Jul 17; 325(5938):336-9.
2009 Apr 15
Osborne RJ, Lin X, Welle S, Sobczak K, O'Rourke JR, Swanson MS, Thornton CA. "Transcriptional and post-transcriptional impact of toxic RNA in myotonic dystrophy." Human molecular genetics.. 2009 Apr 15; 18(8):1471-81. Epub 2009 Feb 17.
2009
Lee MM, Childs-Disney JL, Pushechnikov A, French JM, Sobczak K, Thornton CA, Disney MD. "Controlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: targeting the RNAs that cause myotonic muscular dystrophy." Journal of the American Chemical Society.. 2009 131(47):17464-72.
2008 Nov 25
Sorenson EJ, Windbank AJ, Mandrekar JN, Bamlet WR, Appel SH, Armon C, Barkhaus PE, Bosch P, Boylan K, David WS, Feldman E, Glass J, Gutmann L, Katz J, King W, Luciano CA, McCluskey LF, Nash S, Newman DS, Pascuzzi RM, Pioro E, Sams LJ, Scelsa S, Simpson EP, Subramony SH, Tiryaki E, Thornton CA. "Subcutaneous IGF-1 is not beneficial in 2-year ALS trial." Neurology.. 2008 Nov 25; 71(22):1770-5.
2008 Aug 5
. "A trial of mycophenolate mofetil with prednisone as initial immunotherapy in myasthenia gravis." Neurology.. 2008 Aug 5; 71(6):394-9. Epub 2008 Apr 23.
2008 Mar
Osborne RJ, Thornton CA. "Cell-free cloning of highly expanded CTG repeats by amplification of dimerized expanded repeats." Nucleic acids research.. 2008 Mar; 36(4):e24. Epub 2008 Feb 07.
2008 Jan 15
Ciafaloni E, Mignot E, Sansone V, Hilbert JE, Lin L, Lin X, Liu LC, Pigeon WR, Perlis ML, Thornton CA. "The hypocretin neurotransmission system in myotonic dystrophy type 1." Neurology.. 2008 Jan 15; 70(3):226-30.
2008 Jan
Yadava RS, Frenzel-McCardell CD, Yu Q, Srinivasan V, Tucker AL, Puymirat J, Thornton CA, Prall OW, Harvey RP, Mahadevan MS. "RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression." Nature genetics.. 2008 Jan; 40(1):61-8. Epub 2007 Dec 16.
2008
Gareiss PC, Sobczak K, McNaughton BR, Palde PB, Thornton CA, Miller BL. "Dynamic combinatorial selection of molecules capable of inhibiting the (CUG) repeat RNA-MBNL1 interaction in vitro: discovery of lead compounds targeting myotonic dystrophy (DM1)." Journal of the American Chemical Society.. 2008 130(48):16254-61.
2008
Welle S, Tawil R, Thornton CA. "Sex-related differences in gene expression in human skeletal muscle." PloS one. 2008 3(1):e1385. Epub 2008 Jan 02.
2007 Oct
Wheeler TM, Thornton CA. "Myotonic dystrophy: RNA-mediated muscle disease." Current opinion in neurology.. 2007 Oct; 20(5):572-6.
2007 Sep
Moxley RT, Logigian EL, Martens WB, Annis CL, Pandya S, Moxley RT, Barbieri CA, Dilek N, Wiegner AW, Thornton CA. "Computerized hand grip myometry reliably measures myotonia and muscle strength in myotonic dystrophy (DM1)." Muscle & nerve.. 2007 Sep; 36(3):320-8.
2007 Apr
Lueck JD, Lungu C, Mankodi A, Osborne RJ, Welle SL, Dirksen RT, Thornton CA. "Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1." American journal of physiology. Cell physiology.. 2007 Apr; 292(4):C1291-7. Epub 2006 Nov 29.
2007 Apr
Welle S, Bhatt K, Pinkert CA, Tawil R, Thornton CA. "Muscle growth after postdevelopmental myostatin gene knockout." American journal of physiology. Endocrinology and metabolism.. 2007 Apr; 292(4):E985-91. Epub 2006 Dec 05.
2007 Apr
Logigian EL, Ciafaloni E, Quinn LC, Dilek N, Pandya S, Moxley RT, Thornton CA. "Severity, type, and distribution of myotonic discharges are different in type 1 and type 2 myotonic dystrophy." Muscle & nerve.. 2007 Apr; 35(4):479-85.
2007 Mar
Wheeler TM, Krym MC, Thornton CA. "Ribonuclear foci at the neuromuscular junction in myotonic dystrophy type 1." Neuromuscular disorders : NMD.. 2007 Mar; 17(3):242-7. Epub 2007 Feb 15.
2007 Mar
Margolis RL, Rudnicki DD, Holmes SE, Lin MW, Thornton CA, Ross CA, Margolis RL. "Huntington's disease--like 2 is associated with CUG repeat-containing RNA foci." Annals of neurology.. 2007 Mar; 61(3):272-82.
2007 Feb 20
Osborne RJ, Welle S, Venance SL, Thornton CA, Tawil R. "Expression profile of FSHD supports a link between retinal vasculopathy and muscular dystrophy." Neurology.. 2007 Feb 20; 68(8):569-77. Epub 2006 Dec 06.
2007 Jan
Lueck JD, Mankodi A, Swanson MS, Thornton CA, Dirksen RT. "Muscle chloride channel dysfunction in two mouse models of myotonic dystrophy." The Journal of general physiology. 2007 Jan; 129(1):79-94. Epub 2006 Dec 11.
2007
Yuan Y; Compton SA.; Sobczak K.; Stenberg MG; Thornton CA; Griffith JD; Swanson MS;. "Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs". Nucleic Acids Res.. 2007; .
2007
Wheeler TM, Lueck JD, Swanson MS, Dirksen RT, Thornton CA. "Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy." The Journal of clinical investigation.. 2007 117(12):3952-7.
2006 Oct 15
Osborne RJ, Thornton CA. "RNA-dominant diseases." Human molecular genetics.. 2006 Oct 15; 15 Spec No 2:R162-9.
2006 Aug 1
Kanadia RN, Shin J, Yuan Y, Beattie SG, Wheeler TM, Thornton CA, Swanson MS. "Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy." Proceedings of the National Academy of Sciences of the United States of America.. 2006 Aug 1; 103(31):11748-53. Epub 2006 Jul 24.
2006 Jul 1
Lin X, Miller JW, Mankodi A, Kanadia RN, Yuan Y, Moxley RT, Swanson MS, Thornton CA. "Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy." Human molecular genetics.. 2006 Jul 1; 15(13):2087-97. Epub 2006 May 22.
2006 Jun
Udd B, Meola G, Krahe R, Thornton C, Ranum LP, Bassez G, Kress W, Schoser B, Moxley R. "140th ENMC International Workshop: Myotonic Dystrophy DM2/PROMM and other myotonic dystrophies with guidelines on management." Neuromuscular disorders : NMD.. 2006 Jun; 16(6):403-13. Epub 2006 May 08.
2006
Osborne, RJ; Thornton, CA. "RNA Dominant Diseases". Human Molecular Genetics. 2006; 15: 162-69.
2005 Nov 25
Mankodi A, Lin X, Blaxall BC, Swanson MS, Thornton CA. "Nuclear RNA foci in the heart in myotonic dystrophy." Circulation research.. 2005 Nov 25; 97(11):1152-5. Epub 2005 Oct 27.
2005 Nov 9
Gallo JM, Jin P, Thornton CA, Lin H, Robertson J, D'Souza I, Schlaepfer WW. "The role of RNA and RNA processing in neurodegeneration." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2005 Nov 9; 25(45):10372-5.
2005 Jul
Logigian EL, Blood CL, Dilek N, Martens WB, Moxley RT, Wiegner AW, Thornton CA, Moxley RT. "Quantitative analysis of the "warm-up" phenomenon in myotonic dystrophy type 1." Muscle & nerve.. 2005 Jul; 32(1):35-42.
2004 Apr 13
Logigian EL, Moxley RT, Blood CL, Barbieri CA, Martens WB, Wiegner AW, Thornton CA, Moxley RT. "Leukocyte CTG repeat length correlates with severity of myotonia in myotonic dystrophy type 1." Neurology.. 2004 Apr 13; 62(7):1081-9.
2004 Mar
Welle S, Brooks AI, Delehanty JM, Needler N, Bhatt K, Shah B, Thornton CA. "Skeletal muscle gene expression profiles in 20-29 year old and 65-71 year old women." Experimental gerontology.. 2004 Mar; 39(3):369-77.
2004
Berg J, Jiang H, Thornton CA, Cannon SC. "Truncated ClC-1 mRNA in myotonic dystrophy exerts a dominant-negative effect on the Cl current." Neurology.. 2004 63(12):2371-5.
2004
Jiang H, Mankodi A, Swanson MS, Moxley RT, Thornton CA. "Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons." Human molecular genetics.. 2004 13(24):3079-88. Epub 2004 Oct 20.
2003 Oct
Bachinski LL, Udd B, Meola G, Sansone V, Bassez G, Eymard B, Thornton CA, Moxley RT, Harper PS, Rogers MT, Jurkat-Rott K, Lehmann-Horn F, Wieser T, Gamez J, Navarro C, Bottani A, Kohler A, Shriver MD, Sallinen R, Wessman M, Zhang S, Wright FA, Krahe R. "Confirmation of the type 2 myotonic dystrophy (CCTG)n expansion mutation in patients with proximal myotonic myopathy/proximal myotonic dystrophy of different European origins: a single shared haplotype indicates an ancestral founder effect." American journal of human genetics.. 2003 Oct; 73(4):835-48. Epub 2003 Sep 10.
2003 Sep
Udd B, Meola G, Krahe R, Thornton C, Ranum L, Day J, Bassez G, Ricker K. "Report of the 115th ENMC workshop: DM2/PROMM and other myotonic dystrophies. 3rd Workshop, 14-16 February 2003, Naarden, The Netherlands." Neuromuscular disorders : NMD.. 2003 Sep; 13(7-8):589-96.
2003 Jul 7
Welle S, Brooks AI, Delehanty JM, Needler N, Thornton CA. "Gene expression profile of aging in human muscle." Physiological genomics.. 2003 Jul 7; 14(2):149-59. Epub 2003 Jul 07.
2003 Apr
Welle S, Bhatt K, Shah B, Needler N, Delehanty JM, Thornton CA. "Reduced amount of mitochondrial DNA in aged human muscle." Journal of applied physiology.. 2003 Apr; 94(4):1479-84. Epub 2002 Dec 20.
2003
Kanadia RN, Johnstone KA, Mankodi A, Lungu C, Thornton CA, Esson D, Timmers AM, Hauswirth WW, Swanson MS. "A muscleblind knockout model for myotonic dystrophy." Science.. 2003 302(5652):1978-80.
2003
. "A comparison of muscle strength testing techniques in amyotrophic lateral sclerosis." Neurology.. 2003 61(11):1503-7.
2003
Welle,S.; Bhatt,K.; Shah,B.; Needler,N.; Delehanty,J. M.; Thornton,C. A.;. "Reduced amount of mitochondrial DNA in aged human muscle". Journal of applied physiology: respiratory, environmental and exercise physiology. 2003; 94(4): 1479-1484. Link
2003
Welle,S.; Brooks,A. I.; Delehanty,J. M.; Needler,N.; Thornton,C. A.;. "Gene expression profile of aging in human muscle". Physiological Genomics (Online). 2003; 14(2): 149-159. Link
2003
Mankodi A, Teng-Umnuay P, Krym M, Henderson D, Swanson M, Thornton CA. "Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2." Annals of neurology.. 2003 54(6):760-8.
2002 Oct 22
Thornton CA, Welle SL. "Molecular fingerprints of inflammatory myopathies." Neurology.. 2002 Oct 22; 59(8):1128-9.
2002 Oct
Mankodi A, Thornton CA. "Myotonic syndromes." Current opinion in neurology.. 2002 Oct; 15(5):545-52.
2002 Oct
Wolfe GI, Barohn RJ, Foster BM, Jackson CE, Kissel JT, Day JW, Thornton CA, Nations SP, Bryan WW, Amato AA, Freimer ML, Parry GJ, . "Randomized, controlled trial of intravenous immunoglobulin in myasthenia gravis." Muscle & nerve.. 2002 Oct; 26(4):549-52.
2002 Aug 30
Welle S, Brooks AI, Thornton CA. "Computational method for reducing variance with Affymetrix microarrays." BMC bioinformatics. 2002 Aug 30; 3:23. Epub 2002 Aug 30.
2002 Jul
Mankodi A, Takahashi MP, Jiang H, Beck CL, Bowers WJ, Moxley RT, Cannon SC, Thornton CA. "Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy." Molecular cell. 2002 Jul; 10(1):35-44.
2002 Jun
Welle S, Bhatt K, Shah B, Thornton C. "Insulin-like growth factor-1 and myostatin mRNA expression in muscle: comparison between 62-77 and 21-31 yr old men." Experimental gerontology.. 2002 Jun; 37(6):833-9.
2002 Jan 15
Meola G, Sansone V, Marinou K, Cotelli M, Moxley RT, Thornton CA, De Ambroggi L. "Proximal myotonic myopathy: a syndrome with a favourable prognosis?" Journal of the neurological sciences.. 2002 Jan 15; 193(2):89-96.
2002
Welle,S.; Brooks,A. I.; Thornton,C. A.;. "Computational method for reducing variance with Affymetrix microarrays". BMC bioinformatics [computer file]. 2002; 3: 23. Link
2002
Fougerousse F, Durand M, Lopez S, Suel L, Demignon J, Thornton C, Ozaki H, Kawakami K, Barbet P, Beckmann JS, Maire P. "Six and Eya expression during human somitogenesis and MyoD gene family activation." Journal of muscle research and cell motility. 2002 23(3):255-64.
2001 Sep 15
Mankodi A, Urbinati CR, Yuan QP, Moxley RT, Sansone V, Krym M, Henderson D, Schalling M, Swanson MS, Thornton CA. "Muscleblind localizes to nuclear foci of aberrant RNA in myotonic dystrophy types 1 and 2." Human molecular genetics.. 2001 Sep 15; 10(19):2165-70.
2001 Sep
Musser WS, Barbano RL, Thornton CA, Moxley RT, Herrmann DN, Logigian EL. "Distal myasthenia gravis with a decrement, an increment, and denervation." Journal of clinical neuromuscular disease. 2001 Sep; 3(1):16-9.
2001 Aug 14
Rose MR, McDermott MP, Thornton CA, Palenski C, Martens WB, Griggs RC. "A prospective natural history study of inclusion body myositis: implications for clinical trials." Neurology.. 2001 Aug 14; 57(3):548-50.
2001 Aug 3
Tapscott SJ, Thornton CA. "Biomedicine. Reconstructing myotonic dystrophy." Science.. 2001 Aug 3; 293(5531):816-7.
2001 Mar 8
Welle S, Brooks A, Thornton CA. "Senescence-related changes in gene expression in muscle: similarities and differences between mice and men." Physiological genomics.. 2001 Mar 8; 5(2):67-73. Epub 2001 Mar 08.
2001 Feb 27
Mendell JR, Barohn RJ, Freimer ML, Kissel JT, King W, Nagaraja HN, Rice R, Campbell WW, Donofrio PD, Jackson CE, Lewis RA, Shy M, Simpson DM, Parry GJ, Rivner MH, Thornton CA, Bromberg MB, Tandan R, Harati Y, Giuliani MJ, . "Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy." Neurology.. 2001 Feb 27; 56(4):445-9.
2001
Welle,S.; Brooks,A.; Thornton,C. A.;. "Senescence-related changes in gene expression in muscle: similarities and differences between mice and men". Physiological Genomics (Online). 2001; 5(2): 67-73. Link
2001
Musser, WS; Barbano, R; Thornton, CA; Moxley, RTIII; Herrmann, DN; Logigian, EL. "Distal Myasthenia Gravis with a Decrement, an Increment, and Denervation". J Clin Neuromuscular Disease. 2001; 3(1): 16-19. Link
2000 Sep 8
Mankodi A, Logigian E, Callahan L, McClain C, White R, Henderson D, Krym M, Thornton CA. "Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat." Science.. 2000 Sep 8; 289(5485):1769-73.
2000 Sep 1
Miller JW, Urbinati CR, Teng-Umnuay P, Stenberg MG, Byrne BJ, Thornton CA, Swanson MS. "Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy." The EMBO journal. 2000 Sep 1; 19(17):4439-48.
2000 Jul
Welle S, Bhatt K, Thornton CA. "High-abundance mRNAs in human muscle: comparison between young and old." Journal of applied physiology.. 2000 Jul; 89(1):297-304.
2000 May
Forbes GB, Griggs RC, Moxley RT, Thornton CT, Tawil R. "K-40 and dual-energy X-ray absorptiometry estimates of lean weight compared. Normals and patients with neuromuscular disease." Annals of the New York Academy of Sciences.. 2000 May; 904:111-4.
2000 Jan
Tian B, White RJ, Xia T, Welle S, Turner DH, Mathews MB, Thornton CA. "Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR." RNA.. 2000 Jan; 6(1):79-87.
2000
Welle,S.; Bhatt,K.; Thornton,C. A.;. "High-abundance mRNAs in human muscle: comparison between young and old". Journal of applied physiology: respiratory, environmental and exercise physiology. 2000; 89(1): 297-304. Link
2000
Wax PM, Thornton CA. "Recovery from severe arsenic-induced peripheral neuropathy with 2,3-dimercapto-1-propanesulphonic acid." Journal of toxicology. Clinical toxicology. 2000 38(7):777-80.
1999 Sep 22
Meola G, Sansone V, Perani D, Colleluori A, Cappa S, Cotelli M, Fazio F, Thornton CA, Moxley RT. "Reduced cerebral blood flow and impaired visual-spatial function in proximal myotonic myopathy." Neurology.. 1999 Sep 22; 53(5):1042-50.
1999 Sep 11
Schwid SR, Thornton CA, Pandya S, Manzur KL, Sanjak M, Petrie MD, McDermott MP, Goodman AD. "Quantitative assessment of motor fatigue and strength in MS." Neurology.. 1999 Sep 11; 53(4):743-50.
1999 May
Welle S, Bhatt K, Thornton CA. "Inventory of high-abundance mRNAs in skeletal muscle of normal men." Genome research. 1999 May; 9(5):506-13.
1999 Apr 22
"A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)." Neurology.. 1999 Apr 22; 52(7):1427-33.
1999 Apr
Welle S, Bhatt K, Thornton CA. "Stimulation of myofibrillar synthesis by exercise is mediated by more efficient translation of mRNA." Journal of applied physiology.. 1999 Apr; 86(4):1220-5.
1999 Feb
Mezei MM, Mankodi A, Brais B, Marineau C, Thornton CA, Rouleau GA, Karpati G. "Minimal expansion of the GCG repeat in the PABP2 gene does not predispose to sporadic inclusion body myositis." Neurology.. 1999 Feb; 52(3):669-70.
1999 Jan 1
Thornton CA, Ashizawa T. "Getting a grip on the myotonic dystrophies." Neurology.. 1999 Jan 1; 52(1):12-3.
1999
Welle,S.; Bhatt,K.; Thornton,C. A.;. "Stimulation of myofibrillar synthesis by exercise is mediated by more efficient translation of mRNA". Journal of applied physiology: respiratory, environmental and exercise physiology. 1999; 86(4): 1220-1225. Link
1999
Thornton C. "The myotonic dystrophies." Seminars in neurology. 1999 19(1):25-33.
1998 May
Simmons Z, Thornton CA, Seltzer WK, Richards CS. "Relative stability of a minimal CTG repeat expansion in a large kindred with myotonic dystrophy." Neurology.. 1998 May; 50(5):1501-4.
1998 Apr
Welle S, Thornton CA. "High-protein meals do not enhance myofibrillar synthesis after resistance exercise in 62- to 75-yr-old men and women." The American journal of physiology.. 1998 Apr; 274(4 Pt 1):E677-83.
1997 Oct
Welle S, Thornton C. "Insulin-like growth factor-I, actin, and myosin heavy chain messenger RNAs in skeletal muscle after an injection of growth hormone in subjects over 60 years old." The Journal of endocrinology.. 1997 Oct; 155(1):93-7.
1997 Sep
Welle S, Thornton C, Bhatt K, Krym M. "Expression of elongation factor-1 alpha and S1 in young and old human skeletal muscle." The journals of gerontology. Series A, Biological sciences and medical sciences. 1997 Sep; 52(5):B235-9.
1997 Aug
Thornton CA, Wymer JP, Simmons Z, McClain C, Moxley RT. "Expansion of the myotonic dystrophy CTG repeat reduces expression of the flanking DMAHP gene." Nature genetics.. 1997 Aug; 16(4):407-9.
1996 Nov
Welle S, Totterman S, Thornton C. "Effect of age on muscle hypertrophy induced by resistance training." The journals of gerontology. Series A, Biological sciences and medical sciences. 1996 Nov; 51(6):M270-5.
1996 Sep
Welle S, Thornton C, Statt M, McHenry B. "Growth hormone increases muscle mass and strength but does not rejuvenate myofibrillar protein synthesis in healthy subjects over 60 years old." The Journal of clinical endocrinology and metabolism.. 1996 Sep; 81(9):3239-43.
1996 Jul 15
Thornton CA, Welle S, Griggs RC, Abraham GN. "Human IgG production in vivo: determination of synthetic rate by nonradioactive tracer incorporation." The Journal of immunology : official journal of the American Association of Immunologists.. 1996 Jul 15; 157(2):950-5.
1996 Feb
Welle S, Thornton C, Totterman S, Forbes G. "Utility of creatinine excretion in body-composition studies of healthy men and women older than 60 y." The American journal of clinical nutrition.. 1996 Feb; 63(2):151-6.
1996 Feb
Welle S, Bhatt K, Thornton C. "Polyadenylated RNA, actin mRNA, and myosin heavy chain mRNA in young and old human skeletal muscle." The American journal of physiology.. 1996 Feb; 270(2 Pt 1):E224-9.
1995 Aug
Thornton C, Griggs RC, Moxley RT. "PROMM syndrome (Ricker's disease)" Annals of neurology.. 1995 Aug; 38(2):273.
1995 Mar
Welle S, Thornton C, Statt M. "Myofibrillar protein synthesis in young and old human subjects after three months of resistance training." The American journal of physiology.. 1995 Mar; 268(3 Pt 1):E422-7.
1995 Jan
Rifai Z, Welle S, Kamp C, Thornton CA. "Ragged red fibers in normal aging and inflammatory myopathy." Annals of neurology.. 1995 Jan; 37(1):24-9.
1994 Oct
Welle S, Thornton C, Statt M, McHenry B. "Postprandial myofibrillar and whole body protein synthesis in young and old human subjects." The American journal of physiology.. 1994 Oct; 267(4 Pt 1):E599-604.
1994 Mar
Thornton CA, Griggs RC. "Plasma exchange and intravenous immunoglobulin treatment of neuromuscular disease." Annals of neurology.. 1994 Mar; 35(3):260-8.
1994 Mar
Thornton CA, Griggs RC, Moxley RT. "Myotonic dystrophy with no trinucleotide repeat expansion." Annals of neurology.. 1994 Mar; 35(3):269-72.
1994 Jan
Thornton CA, Johnson K, Moxley RT. "Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes." Annals of neurology.. 1994 Jan; 35(1):104-7.
1994
Houston S, Thornton C, Emmanuel J, Latif A. "Human T cell lymphotropic virus type 1 in Zimbabwe." Transactions of the Royal Society of Tropical Medicine and Hygiene.. 1994 88(2):170-2.
1993 May
Welle S, Thornton C, Jozefowicz R, Statt M. "Myofibrillar protein synthesis in young and old men." The American journal of physiology.. 1993 May; 264(5 Pt 1):E693-8.
1992 Sep
Thornton CA, Houston S, Latif AS. "Neurocysticercosis and human immunodeficiency virus infection. A possible association." Archives of neurology.. 1992 Sep; 49(9):963-5.
1991 Nov
Neves O, Stein CM, Thornton C, Gangaidzo I, Thomas JE. "Rhabdomyolysis associated with human immunodeficiency virus (HIV) infection." The Central African journal of medicine. 1991 Nov; 37(11):387-8.
1991 Jun
Thornton CA, Latif AS, Emmanuel JC. "Guillain-Barré syndrome associated with human immunodeficiency virus infection in Zimbabwe." Neurology.. 1991 Jun; 41(6):812-5.

Books

2011
Thornton, CA. "Myotonic Dystrophy". Muscle: Fundamental Biology and Mechanisms and Disease. Hill JA, Stull JT, Sweeney HL, Olson, EN. : Elsevier, 2011.
2009
Day J, Thornton C. "Myotonic Dystrophy". Disorders of Voluntary Muscle. Karpati G, Hilton-Jones D, Bushbby K, Griggs RC. Cambridge UK: Cambridge University Press, 2009.
2006
Thornton CA, Swanson MS, Cooper TA. "The RNA-Mediated Disease Process in Myotonic Dystrophy". Genetic Instabilities and Neurological Diseases. Wells R, Ashizawa T. San Diego, CA: Elsevier, 2006. 37-54
2006
Lim LE, Thornton CA, Rando TA. "Muscular Dystrophies". Neurobiology of Disease. San Diego, CA: Elsevier, 2006. 925-934
2006
Lim LE, Thornton CA, Rando TA. "Muscular Dystrophies". Neurobiology of Disease. Gilman,S. San Diego: Elsevier, 2006. 925-934
2004
Thornton C; Griggs RC. "Neurogenetics". Cecil Textbook of Medicine. Goldman L; Ausiello D. Philadelphia, PA: Saunders Co., 2004. 2211-2212
2002
Thornton C. "Myopathies Based on Complex Molecular Defects: Repeat Expansion Diseases. The Myotonic Dystrophies". Structural and Molecular Basis of Skeletal Muscle Disease. Karpati G; Olsson Y. : Neuropath Press, 2002.
1999
Moxley RT III; Tawil R; Thornton C. "Channelopathies: Myotonic Disorders and Periodic Paralysis". Pediatric Neurology. Principles and Practice. Swaiman KF; Ashwal S. St Louis: Mosby, 1999. 1299-1310