Charles A. Thornton, M.D.

Charles A. Thornton, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 645
Rochester, NY 14642

Office: (585) 275-2542
Fax: (585) 276-1947
Administrative: (585) 275-2542
Lab: (585) 275-7108

Bio

The biographical information for Charles A. Thornton, M.D. is not currently available.

Awards & Honors (National)

Hans Steinert Award for Myotonic Dystrophy Research 2011
Norman Saunders Jacob's Ladder International Research Prize 2010

Awards & Honors (Local)

Carrell-Krusen Award | University of Texas Southwestern, Dallas, TX 2013
Paul B Beeson Physician Faculty Scholar Award | American Federation of Aging Research 1997 - 2000
Awardee, Clinical Investigator Development | NIH/NINDS 1992 - 1997
Awardee, Experimental Therapeutics Fellowship | NRSA 1991 - 1992
Awardee, Research Fellowship | Muscular Dystrophy Association 1989 - 1991
Fulbright Senior Lecturing Award 1987 - 1989
Merck Award for Medical Student Achievement 1981
Borts Student Research Award 1980

Patents

Muscleblind Gene Therapy for RNA-Mediated Disease

United States Serial NO.: 10/591,883
Filed Date: March 10, 2005
Title: Methods and Compositions For Treatment of Diseases Associated with Aberrant Microsatellite Expansion
Invented by: Charles Thornton, Maurice Swanson, Rahul Kanadia
Physician Checklists for FSHD (Facioscapulohumeral Muscular Dystrophy) and DM (Myotonic Dystrophy)

United States Serial NO.: 1-686888271
Filed Date: November 16, 2011
Title: Physician Checklists for FSHD (Facioscapulohumeral Muscular Dystrophy) and DM (Myotonic Dystrophy)
Invented by: Richard Moxley, III, Al-Rabi Tawil, Charles Thornton, Michael McDermott
Patient Information Forms for FSHD (Facioscapulohumeral Muscular Dystrophy), DM (Myotonic Dystrophy), and Unaffected Blood Relatives of Individuals with FSHD or DM

United States Serial NO.: 1-686948337
Filed Date: November 16, 2011
Title: Patient Information Forms for FSHD (Facioscapulohumeral Muscular Dystrophy), DM (Myotonic Dystrophy), and Unaffected Blood Relatives of Individuals with FSH
Invented by: Richard Moxley, III, Al-Rabi Tawil, Charles Thornton, Michael McDermott

Recent Journal Articles

Showing the 5 most recent journal articles. 122 available »

2014 Sep 24
Batra R, Charizanis K, Manchanda M, Mohan A, Li M, Finn DJ, Goodwin M, Zhang C, Sobczak K, Thornton CA, Swanson MS. "Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease." Molecular cell.. 2014 Sep 24; Epub 2014 Sep 24.
2014 Aug
Thornton CA. "Myotonic dystrophy." Neurologic clinics.. 2014 Aug; 32(3):705-19, viii. Epub 2014 Jun 06.
2014 Jun
Heatwole C, Bode R, Johnson N, Dekdebrun J, Dilek N, Heatwole M, Hilbert JE, Luebbe E, Martens W, McDermott MP, Rothrock N, Thornton C, Vickrey BG, Victorson D, Moxley R. "Myotonic Dystrophy Health Index: initial evaluation of a disease-specific outcome measure." Muscle & nerve.. 2014 Jun; 49(6):906-14.
2014
Hoskins JW, Ofori LO, Chen CZ, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan JJ, Zheng W, Austin CP, Disney MD, Miller BL, Thornton CA. "Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects." Nucleic acids research.. 2014 42(10):6591-602. Epub 2014 May 05.
2013 Feb
Sobczak K, Wheeler TM, Wang W, Thornton CA. "RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy." Molecular therapy : the journal of the American Society of Gene Therapy.. 2013 Feb; 21(2):380-7. Epub 2012 Nov 27.

Current Appointments

Saunders Family Distinguished Professor in Neuromuscular Research - Department of Neurology (SMD)
Professor - Department of Neurology, NMD (SMD) - Primary

Specialties

Neurology - American Board of Psychiatry and Neurology

Education

MD | Medicine | University Iowa Coll Medicine1981
BS | Arts & Sciences | University of Iowa1977

Post-Doctoral Training & Residency

Fellowship in Experimental Therapeutics at University of Rochester School of Medicine & Dentistry09/01/1990 - 06/30/1992
Fellowship in Neuromuscular Disease at University of Rochester School of Medicine & Dentistry09/01/1989 - 06/30/1990
Residency in Neurology at Oregon Health Sciences University School of Med09/01/1982 - 06/30/1985
Internship in Internal Medicine at UCLA School of Medicine09/01/1981 - 06/30/1982