Charles A. Thornton, M.D.

Charles A. Thornton, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 645
Rochester, NY 14642

Office: (585) 275-2542
Fax: (585) 276-1947
Administrative: (585) 275-2542
Lab: (585) 275-7108

Bio

The biographical information for Charles A. Thornton, M.D. is not currently available.

Patents

Muscleblind Gene Therapy for RNA-Mediated Disease

United States Serial NO.: 10/591,883
Filed Date: March 10, 2005
Title: Methods and Compositions For Treatment of Diseases Associated with Aberrant Microsatellite Expansion
Invented by: Charles Thornton, Maurice Swanson, Rahul Kanadia
Physician Checklists for FSHD (Facioscapulohumeral Muscular Dystrophy) and DM (Myotonic Dystrophy)

United States Serial NO.:
Filed Date: November 16, 2011
Title: Physician Checklists for FSHD (Facioscapulohumeral Muscular Dystrophy) and DM (Myotonic Dystrophy)
Invented by: Richard Moxley, III, Al-Rabi Tawil, Charles Thornton, Michael McDermott
Patient Information Forms for FSHD (Facioscapulohumeral Muscular Dystrophy), DM (Myotonic Dystrophy), and Unaffected Blood Relatives of Individuals with FSHD or DM

United States Serial NO.: TXu 1-790-681
Filed Date: November 16, 2011
Title: Patient Information Forms for FSHD (Facioscapulohumeral Muscular Dystrophy), DM (Myotonic Dystrophy), and Unaffected Blood Relatives of Individuals with FSH
Invented by: Richard Moxley, III, Al-Rabi Tawil, Charles Thornton, Michael McDermott

Awards & Honors (National)

Hans Steinert Award for Myotonic Dystrophy Research 2011
Norman Saunders Jacob's Ladder International Research Prize 2010

Awards & Honors (Local)

Carrell-Krusen Award | University of Texas Southwestern, Dallas, TX 2013
Paul B Beeson Physician Faculty Scholar Award | American Federation of Aging Research 1997 - 2000
Awardee, Clinical Investigator Development | NIH/NINDS 1992 - 1997
Awardee, Experimental Therapeutics Fellowship | NRSA 1991 - 1992
Awardee, Research Fellowship | Muscular Dystrophy Association 1989 - 1991
Fulbright Senior Lecturing Award 1987 - 1989
Merck Award for Medical Student Achievement 1981
Borts Student Research Award 1980

Recent Journal Articles

Showing the 5 most recent journal articles. 119 available »

2013 Oct 19
Heatwole C, Bode R, Johnson N, Dekdebrun J, Dilek N, Heatwole M, Hilbert JE, Luebbe E, Martens W, McDermott MP, Rothrock N, Thornton C, Vickrey BG, Victorson D, Moxley R. "The myotonic dystrophy health index: Initial evaluation of a new outcome measure." Muscle & nerve.. 2013 Oct 19; Epub 2013 Oct 19.
2013 Feb
Sobczak K, Wheeler TM, Wang W, Thornton CA. "RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy." Molecular therapy : the journal of the American Society of Gene Therapy.. 2013 Feb; 21(2):380-7. Epub 2012 Nov 27.
2013
Childs-Disney JL, Stepniak-Konieczna E, Tran T, Yildirim I, Park H, Chen CZ, Hoskins J, Southall N, Marugan JJ, Patnaik S, Zheng W, Austin CP, Schatz GC, Sobczak K, Thornton CA, Disney MD. "Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules." Nature communications. 2013 4:2044.
2013
Nakamori M, Sobczak K, Puwanant A, Welle S, Eichinger K, Pandya S, Dekdebrun J, Heatwole CR, McDermott MP, Chen T, Cline M, Tawil R, Osborne RJ, Wheeler TM, Swanson M, Moxley RT, Thornton CA. "Splicing biomarkers of disease severity in myotonic dystrophy." Annals of neurology.. 2013 74(6):862-72.
2013
Axford MM, Wang YH, Nakamori M, Zannis-Hadjopoulos M, Thornton CA, Pearson CE. "Detection of slipped-DNAs at the trinucleotide repeats of the myotonic dystrophy type I disease locus in patient tissues." PLoS genetics.. 2013 9(12):e1003866. Epub 2013 Dec 19.

Current Appointments

Saunders Family Distinguished Professor in Neuromuscular Research - Department of Neurology (SMD)
Professor - Department of Neurology, NMD (SMD) - Primary

Specialties

Neurology - American Board of Psychiatry and Neurology

Education

MD | Medicine | University Iowa Coll Medicine1981
BS | Arts & Sciences | University of Iowa1977

Post-Doctoral Training & Residency

Fellowship in Experimental Therapeutics at University of Rochester School of Medicine & Dentistry09/01/1990 - 06/30/1992
Fellowship in Neuromuscular Disease at University of Rochester School of Medicine & Dentistry09/01/1989 - 06/30/1990
Residency in Neurology at Oregon Health Sciences University School of Med09/01/1982 - 06/30/1985
Internship in Internal Medicine at UCLA School of Medicine09/01/1981 - 06/30/1982