Research Bio
Dr. Miyamoto's research focuses on the molecular mechanisms of androgen receptor (AR) functions in genitourinary cancers. He studied the AR as a postdoctoral research associate under the mentorship of Dr. Chawnshang Chang and then as a research assistant professor at the University of Rochester. He is currently working on projects analyzing new types of antiandrogens and novel AR co-activators in prostate cancer, which may provide molecular targets for treatment of androgen-dependent and androgen-independent tumors. He demonstrated that androgens promote bladder carcinogenesis and cancer progression (JNCI, 2007) and is also investigating underlying mechanisms of the effects through the AR.
2013 May
Hsu JW, Hsu IW, Xu D, Miyamoto H, Liang L, Wu XR, Shyr CR, Chang C. "Decreased tumorigenesis and mortality from bladder cancer in mice lacking urothelial androgen receptor." The American journal of pathology. 2013 May 0; 182(5):1811-20. Epub 2013 Mar 13. |
2013 May
Yang DR, Lin SJ, Ding XF, Miyamoto H, Messing E, Li LQ, Wang N, Chang C. "Higher Expression of Peroxisome Proliferator-activated Receptor ? or Its Activation by Agonist Thiazolidinedione-rosiglitazone Promotes Bladder Cancer Cell Migration and Invasion." Urology. 2013 May 0; 81(5):1109.e1-6. Epub 2013 Mar 19. |
2013 Apr 2
Kakiuchi Y, Choy B, Gordetsky J, Izumi K, Wu G, Rashid H, Joseph JV, Miyamoto H. "Role of frozen section analysis of surgical margins during robot-assisted laparoscopic radical prostatectomy: a 2608-case experience." Human pathology. 2013 Apr 2; Epub 2013 Apr 02. |
2013 Apr
Kawahara T, Ito H, Terao H, Miyamoto H, Uemura H, Kubota Y, Matsuzaki J. "Authors' response to chew and lange." Journal of endourology / Endourological Society. 2013 Apr 0; 27(4):507. Epub 2013 Mar 15. |
2013 Apr
Ishiguro Y, Ishiguro H, Miyamoto H. "Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Up-regulates Interleukin-6 in Cancer Cells and Induces Subsequent Development of Interstitial Pneumonia." . 2013 Apr 0; 4(4):550-9. |