Guan Wu, M.D., Ph.D.

Guan Wu, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 656
Rochester, NY 14642

Office: (585) 275-1700
Fax: (585) 273-1068

Professional Bio

We are pleased to welcome Guan Wu, MD, PhD to the Department of Urology at the University of Rochester Medical Center. Dr. Wu has joined our growing research and clinical faculty, extending our knowledge and our ability to offer our patients the best care possible. Dr. Wu has been working on identifying and characterizing biochemical defects in kidney cancer cells. His laboratory is also analyzing the genetics of human kidney cancer specimens, specifically to identify tumor markers.

Dr. Wu is performing minimally invasive and robotic surgery and also sees general urology patients in our offices in Canandaigua, Clifton Springs and Rochester. He specializes in laparoscopic surgery, general urology and kidney cancer research.

Dr. Wu is a double doctorate graduate of the Beijing Medical University School of Medicine. He also completed his post-doctoral training at the University of Iowa Hospital and Strong Memorial Hospital. His dual residencies allow him to see surgical urology patients.

Research Bio

The long-term goal of Dr. Wu's research is to refine our knowledge of the biology of kidney cancer. Currently, Dr. Wu's laboratory is studying genetic defects in kidney cancer cells and how these defects cause the disease.

Dr. Wu's laboratory has been working on the proteins produced by cancer critical genes. He and his associates are learning how the cellular and biochemical functions of these proteins cause kidney cancer to develop and progress. Dr. Wu's laboratory has identified several such complexes by purifying them from kidney cancer cell lines and by using yeast as a human protein carrier. This research is not only extending our understanding of kidney cancer, but also has broader implications for normal cell physiology.

Dr. Wu's laboratory is also analyzing the genetics of human kidney cancer specimens to look into DNA mutations. This research will be combined with the studies done with kidney cancer cell lines. Together, they will help us discover and validade new "tumor markers" (substances produced by the body that can indicate the presence of a specific cancer). This, in turn, will help us develop new ways to diagnose and treat kidney cancer.

Awards & Honors (National)

America's Top Doctor | U.S. News & World Report and Castle Connolly America 2011
Praecis Pharmaceuticals/AUA Gerald P. Murphy Scholar 2004 - 2004
The Pfizer Scholars in Urology Award 1996 - 1996
Smithkline-Beecham Travel Award | Society for Basic Urologic Research 1995 - 1995

Awards & Honors (Local)

The Robert S. Davis, M.D. Faculty Teaching Award | University of Rochester Medical Center / Department of Urology | Rochester, New York 2011
Honorary Director of the Department of Urology | Nanjing Drum Tower Hospital, Nanjing University Medical School 2011
Honored Visiting Professor of the Second Medical School and Tianjin Institute of Urology | Tianjin Medical University | Tianjin, China 2008 - 2008
The AUA Northeastern Section Young Investigator Award 2007 - 2007
Outstanding Graduate Student Award | Beijing Medical University 1985 - 1985
Outstanding Medical Student Award | Beijing University 1982 - 1982

Recent Journal Articles

Showing the 5 most recent journal articles. 55 available »

Tobis S, Venigalla S, Scosyrev E, Lloyd LG, Golijanin D, Joseph JV, Rashid H, Wu G. "Analysis of a large single-center experience with robot-assisted pyeloplasty". Int J Urol. 2013; 20(2): 230-4.
Scosyrev E, Donsky H, Tobis S, Wu G, Joseph J, Rashid H, Messing, E. "Statin use and the risk of biochemical recurrence of prostate cancer after definitive local therapy: A meta-analysis of eight cohort studies". BJU Int. 2013; 111(36): E71-E77.
Gaur K, Li J, Wang D, Dutta P, Yan SJ, Tsurumi A, Land H, Wu G, Li W. "The Birt-Hogg-Dube tumor suppressor Folliculin negatively regulates ribosomal RNA synthesis". Hum Mol Genet. 2013; 22(2): 284-99.
Kakiuchi Y, Choy B, Gordetsky J, Izumi K, Wu G, Rashid H, Joseph J, Miyamoto. "Role of frozen section analysis of surgical margins during robot-assisted laparoscopic radical prostatectomy: A 2,608-case experience". Human Pathology. 2013; 44(8): 1556-1562.
Tobis S, Houman J, Mastrodenato, K, Rashid H, Wu G. "Robotic repair of post-cystectomy ureteroileal anastomotic strictures: Techniques for success". J Laparoendosc Adv Surg Tech A. 2013; 23(6): 526-9.

Current Appointments

Associate Professor - Department of Urology (SMD) - Primary
Associate Professor - Department of Pathology and Laboratory Medicine (SMD)
Associate Professor - Cancer Center


Urology - American Board of Urology


PhD | Urology | China-Beijing Medical University1989
MD | Medicine | China-Beijing Medical University1983

Post-Doctoral Training & Residency

Residency in Urology at University of Rochester School of Medicine & Dentistry07/01/2002 - 06/30/2006
Residency in Surgery at University of Rochester School of Medicine & Dentistry06/26/2001 - 06/25/2002
Internship in Surgery at University of Rochester School of Medicine & Dentistry06/26/2000 - 06/25/2001