Edward M. Schwarz, Ph.D.

Edward M. Schwarz, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 665
Rochester, NY 14642

Research Bio

Dr. Schwarz is Professor of Orthopaedics and Associate Director of the
Center for Musculoskeletal Research at URMC. His laboratory focuses on
finding solutions to bone loss due to conditions such as rheumatoid
arthritis, infections, tumors that spread to bone, and bone destruction near
the implants used in reconstructive surgery.



Several genes are known to turn on the healing process in bone. Dr.
Schwarz's group loads these genes into harmless virus particles. The
particles are coated onto experimental bone implants to deliver therapeutic
genes to the area of reconstruction, thus improving bone healing. The
cartilage that lines joints in mice can be encouraged to heal more
completely when virus particles deliver therapeutic genes too.

An additional interest of Dr. Schwarz's lab is the use of magnetic resonance
imaging (MRI) and high resolution computed tomography (CT) scans to
visualize the formation of new blood vessels as patients heal.

Awards & Honors (Local)

J.R. Neff Award, Musculoskeletal Research Foundation 2007
Orthopaedic Research Society's Kappa Delta Young Investigator Award 2005
Orthopaedic Research Society's Harris Award 2003
New Investigator Research Award, The Association of Bone & Joint Surgeons . 1999
University of Rochester Nominee for the Sinshimmer Award. 1999
University of Rochester Nominee for the Elison Award. 1999

Recent Journal Articles

Showing the 5 most recent journal articles. 204 available »

2014 Jun
Papuga MO, Beck CA, Kates SL, Schwarz EM, Maloney MD. "Validation of GAITRite and PROMIS as high-throughput physical function outcome measures following ACL reconstruction." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2014 Jun; 32(6):793-801. Epub 2014 Feb 14.
2014 May
Yukata K, Xie C, Li TF, Takahata M, Hoak D, Kondabolu S, Zhang X, Awad HA, Schwarz EM, Beck CA, Jonason JH, O'Keefe RJ. "Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment." Bone.. 2014 May; 62:79-89. Epub 2014 Feb 12.
2014 Apr
Inzana JA, Olvera D, Fuller SM, Kelly JP, Graeve OA, Schwarz EM, Kates SL, Awad HA. "3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration." Biomaterials.. 2014 Apr; 35(13):4026-34. Epub 2014 Feb 14.
2014 Mar 15
Bouta EM, Wood RW, Brown EB, Rahimi H, Ritchlin CT, Schwarz EM. "In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice." The Journal of physiology.. 2014 Mar 15; 592(Pt 6):1213-23. Epub 2014 Jan 13.
2014 Mar
Long T, Zhu Z, Awad HA, Schwarz EM, Hilton MJ, Dong Y. "The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice." Biomaterials.. 2014 Mar; 35(9):2752-9. Epub 2014 Jan 03.

Current Appointments

Director - Center for Musculoskeletal Research - Primary Administrative
Richard and Margaret Burton Distinguished Professor in Orthopaedics - Department of Orthopaedics (SMD)
Professor - Department of Orthopaedics, Center for Musculoskeletal Research (SMD) - Primary
Professor - Department of Biomedical Engineering (SMD)
Professor - Department of Medicine, Allergy/Immunology and Rheumatology (SMD)
Professor - Department of Microbiology and Immunology (SMD)
Professor - Department of Pathology and Laboratory Medicine (SMD)
Professor - Department of Urology (SMD)

Education

PhD | Immunology, All Other | Einstein College Medicine1993
MA | Immunology, All Other | Einstein College Medicine1990
BS | Biology | Worcester Polytech Inst1988

Post-Doctoral Training & Residency

Laboratory of Inder M. Verma, Ph.D., Laboratory of Genetics The Salk Institute, La Jolla, California, Concentrations: Gene Therapy, NFkB Signal, Transduction, Transgenic Mice. 1997
Training - Pre-doctoral Fellow, Laboratory of Barry R. Bloom, Ph.D., Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York 1993
Training - Summer Student - Laboratory of Carl Shilkraut, Ph.D., Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York 0
Training - Undergraduate Research Laboratory of Donald J. Tipper, Ph.D., Department of Microbiology & Molecular Genetics, University of Massachusetts Medical School, Worcester, Massachusetts 1988
Training - Summer Student - Laboratory of Fritz Herz, Ph.D., Department of Pathology, Montefiore Medical Center, Bronx, New York 0