Professional Bio
Fellowship Director, Pediatric Nephrology
Research Bio
Hypertension is estimated to affect 50 million Americans and is a leading cause of cardiovascular disease, stroke, and kidney disease. Although such morbid events as stroke and myocardial infarction are uncommon in childhood, it is clear that the origins of cardiovascular disease and essential hypertension begin early in life and that hypertensive end-organ damage may occur at a young age. Understanding the early time course in how hypertension affects the susceptible organs is important, so that strategies to prevent the development of target-organ damage can be developed.
Dr. Lande is studying vascular changes as markers of early hypertensive target-organ damage in children. In addition, he is studying the neurocognitive effects of hypertension in children and determining any potential benefit of antihypertensive therapy on cognition. He is also focusing on the psychological correlates of hypertension in children.
2011
Lande MB, Gerson AC, Hooper SR, Cox C, Matheson M, Mendley SR, Gipson DS, Wong Cynthia, Warady BA, Furth SL, Flynn JT. "Casual Blood Pressure and Neurocognitive Function in Children with Chronic Kidney Disease: A Report of the Children with Chronic Kidney Disease Cohort Study". Clin J Am Soc Nephrol. 2011; 6: 1831-37. |
2011
Hooper SR, Gerson AC, Butler RW, Gipson DS, Mendley SR, Lande MB, Shinnar S, Wentz A, Matteson M, Cox C, Furth SL, Warady BA. "Neurocognitive functioning of children and adolescents with mild-to-moderate chronic kidney disease". Clin J Am Soc Nephrol. 2011; 6: 1824-30. |
2010
Gerson AC, Wentz A, Abraham AG, Mendley SR, Hooper SR, Butler RW, Gipson DS, Lande MB, Shinnar S, Moxey-Mims MM, Warady BA, Furth SL. "Health-related quality of life of children with mild to moderate chronic kidney disease". Pediatrics. 2010; 125(2): e349-57. |
2010
Lande MB, Adams H, Falkner B, Waldstein SR, Schwartz GJ, Szilagyi PG, Wang H, Palumbo D. "Parental assessment of executive function and internalizing and externalizing behavior in primary hypertension after anti-hypertensive therapy". J Pediatr. 2010; 157(1): 114-9. |
2010
Jo CO, Lande MB, Meagher CC, Wang H, Vermilion RP. "A simple method of measuring thoracic aortic pulse wave velocity in children: Methods and normal values." J Am Soc Echocardiogr. 2010; 23: 735-40. |
