Lawrence J. Saubermann, M.D.

Lawrence J. Saubermann, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 667
Rochester, NY 14642

Fax: (585) 276-0101

Journal Articles

Showing all 37 journal articles available.

2013
Roy A, Gaylo A, Cao W, Saubermann LJ, Lawrence BP. "Neither direct nor developmental exposure to bisphenol A alters the severity of experimental inflammatory colitis in mice." Journal of immunotoxicology. 2013 10(4):334-40. Epub 2013 Jan 03.
2012 Jun
Mohanty PH, Sood V, Saubermann LJ. "A 16-year-old girl with perianal skin tags." Pediatric annals. 2012 Jun; 41(6):10-2.
2010 May 1
Zhang L, Sun W, Wang J, Zhang M, Yang S, Tian Y, Vidyasagar S, Peña LA, Zhang K, Cao Y, Yin L, Wang W, Zhang L, Schaefer KL, Saubermann LJ, Swarts SG, Fenton BM, Keng PC, Okunieff P. "Mitigation effect of an FGF-2 peptide on acute gastrointestinal syndrome after high-dose ionizing radiation." International journal of radiation oncology, biology, physics.. 2010 May 1; 77(1):261-8.
2010 May
Zhang L; Sun W; Wang J; Zhang M; Yang S; Tian Y; Vidyasagar S; Pena LA; Zhang K; Cao Y; Yin L; Wang W; Zhang L; Schaefer KL; Saubermann LJ; Swarts SG; Fenton BM; Keng PC; Okunieff P. "Mitigation effect of an FGF-2 peptide on acute gastrointestinal syndrome after high-dose ionizing radiation". Int J Radiat Oncol Biol Phys. 2010; 77(1): 261-8.
2010
Schaefer KL; Harris G; Jasalavich CA; Morales VM; Saubermann LJ. "PPAR gamma suppresses early phase but increases late phase production of IL-8 in TNFa-stimulated intestinal epithelial cells". To be submitted. 2010; .
2008
Kobayashi N; Inamori M; Fujita K; Fujisawa T; Fujisawa N; Takahashi H; Yoneda M; Abe Y; Kawamura H; Shimamura T; Kirikoshi H; Kubota K; Sakaguchi T; Saito S; Saubermann LJ; Nakajima A. "Characterization of K-ras gene mutations in association with mucinous hypersecretion in intraductal papillary-mucinous neoplasms". J Hepatobiliary Pancreat Surg. 2008; 15(2): 169-77.
2008
Kobayashi N, Inamori M, Fujita K, Fujisawa T, Fujisawa N, Takahashi H, Yoneda M, Abe Y, Kawamura H, Shimamura T, Kirikoshi H, Kubota K, Sakaguchi T, Saito S, Saubermann LJ, Nakajima A. "Characterization of K-ras gene mutations in association with mucinous hypersecretion in intraductal papillary-mucinous neoplasms." Journal of hepato-biliary-pancreatic surgery. 2008 15(2):169-77. Epub 2008 Apr 06.
2007 Feb 1
Schaefer KL, Takahashi H, Morales VM, Harris G, Barton S, Osawa E, Nakajima A, Saubermann LJ. "PPARgamma inhibitors reduce tubulin protein levels by a PPARgamma, PPARdelta and proteasome-independent mechanism, resulting in cell cycle arrest, apoptosis and reduced metastasis of colorectal carcinoma cells." International journal of cancer. Journal international du cancer.. 2007 Feb 1; 120(3):702-13.
2007 Feb
Probert CS, Saubermann LJ, Balk S, Blumberg RS. "Repertoire of the alpha beta T-cell receptor in the intestine." Immunological reviews. 2007 Feb; 215:215-25.
2007
Probert CS, Saubermann LJ, Balk S, Blumberg RS. "Repertoire of the alpha beta T-cell receptor in the intestine". Immunol Rev. 2007; 215: 215-25.
2007
Kugathasan S Md, Saubermann LJ, Smith L, Kou D, Itoh J, Binion D, Levine A, Blumberg R, Fiocchi C Md. "Mucosal T-cell immunoregulation varies in early and late Crohn's disease". Gut. 2007; 56(12): 1696-705.
2006 Sep
Takahashi H, Fujita K, Fujisawa T, Yonemitsu K, Tomimoto A, Ikeda I, Yoneda M, Masuda T, Schaefer K, Saubermann LJ, Shimamura T, Saitoh S, Tachibana M, Wada K, Nakagama H, Nakajima A. "Inhibition of peroxisome proliferator-activated receptor gamma activity in esophageal carcinoma cells results in a drastic decrease of invasive properties." Cancer science. 2006 Sep; 97(9):854-60. Epub 2006 Jun 29.
2006
Takahash Hi, Fujita K, Fujisawa T, Yonemitsu K, Tomimoto A, Ikeda I, Yoneda M, Masuda T, Schaefer K, Saubermann LJ, Shimamura T, ,Saitoh S, Tachibana M, Wada K, Nakagama H, Nakajima A. "Inhibition of peroxisome proliferator-activated receptor gamma activity in esophageal carcinoma cells results in a drastic decrease of invasive properties". Cancer Science. 2006; 97(9): 854-860.
2006
Dendrinos K, Becker J, Stucchi A, Saubermann L, LaMorte W, Farraye F. "Anti-Saccharomyces Cerevisiae Antibodies are Associated with the Development of Postoperative Fistulas Following Ileal Pouch-Anal Anastomosis". Journal of Gastrointestinal Surgery. 2006; 10(7): 1060-1064.
2006
Dendrinos KG, Becker JM, Stucchi AF, Saubermann LJ, LaMorte W, Farraye FA. "Anti-Saccharomyces cerevisiae antibodies are associated with the development of postoperative fistulas following ileal pouch-anal anastomosis." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2006 10(7):1060-4.
2005 Mar 15
Schaefer KL, Wada K, Takahashi H, Matsuhashi N, Ohnishi S, Wolfe MM, Turner JR, Nakajima A, Borkan SC, Saubermann LJ. "Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells." Cancer research.. 2005 Mar 15; 65(6):2251-9.
2005 Mar
Schaefer KL, Denevich S, Ma C, Cooley SR, Nakajima A, Wada K, Schlezinger J, Sherr D, Saubermann LJ. "Intestinal antiinflammatory effects of thiazolidenedione peroxisome proliferator-activated receptor-gamma ligands on T helper type 1 chemokine regulation include nontranscriptional control mechanisms." Inflammatory bowel diseases.. 2005 Mar; 11(3):244-52.
2005
Schaefer KL, Ma C, Denevich S, Cooley SR, Schlezinger J, Sherr D and Saubermann LJ. "Thiazolidenedione PPAR? ligands reduce production of the Th1-attracting chemokine CXCL10 and reduce T cell Numbers in the murine colon in association with post-transcriptional regulation". Inflammatory Bowel Diseases. 2005; 11(3): 244-52.
2005
Schaefer KL, Wada K, Takahashi H, Matsuhashi N, Ohnishi S, Wolfe MM, Turner JR, Nakajima A, Borkan SC, Saubermann LJ. "Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells". Cancer Research. 2005; 15(65): 2251-9.
2004 Aug
Wada K, Nakajima A, Takahashi H, Yoneda M, Fujisawa N, Ohsawa E, Kadowaki T, Kubota N, Terauchi Y, Matsuhashi N, Saubermann LJ, Nakajima N, Blumberg RS. "Protective effect of endogenous PPARgamma against acute gastric mucosal lesions associated with ischemia-reperfusion." American journal of physiology. Gastrointestinal and liver physiology.. 2004 Aug; 287(2):G452-8.
2002 Sep
Saubermann LJ, Nakajima A, Wada K, Zhao S, Terauchi Y, Kadowaki T, Aburatani H, Matsuhashi N, Nagai R, Blumberg RS. "Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis." Inflammatory bowel diseases.. 2002 Sep; 8(5):330-9.
2002
Nakajima, A.; Wada, K.; Katayama, K.; Saubermann, LJ.; Oswa, E.; Nagase, H.; Ueno, N.; Matsuhashi, N.; Aburatani, H. "Gene Expression Profile After Peroxisome Proliferator Activator Receptor-Gamma Ligand Administration in Dextran Sodium Sulfate Mice." Journal Gastroenterology. 2002; 14: 62-66. Link
2002
Matsuhashi, N.; Nakajima, A.; Wada, K.; Miki, H.; Saubermann, LJ.; Kubota, N.; Terauchi, Y.; Kadowaki, T.; Nagai, R.; Blumberg, RS. "Protective Effects of PPARy in Gastrointestinal Mucosal Injuries." Immunology. 2002; 4: 227-233. Link
2001
Nakajima A.; Wada, K.; Miki, H.; Kubota, N.; Nakajima, N.; Terauchi, Y.; Ohnishi, S.; Saubermann, LJ.; Kadowaki, T.; Blumberg, RS.; Nagai, R.; Matsuhashi, N. "Endogenous PPARgamma Mediates Anti-inflammatory Activity in Murine Ischemia-Receperfusion Injury." Gstroenterology. 2001; 120(2): 460-469. Link
2001
Probert, CS.; Chott, A.; Saubermann, LJ.; Stevens, AC.; Balk, SP.; Blumberg, RS. "Prevalence of an Ulcerative Colitis-Associated CD8+ T Cell Receptor Beta-Chain CDR3-Region Motif and it's Association With Disease Activity." Journal Clinical Immunology. 2001; 21(2): 126-134. Link
2000 Oct
Mizoguchi A, Mizoguchi E, Saubermann LJ, Higaki K, Blumberg RS, Bhan AK. "Limited CD4 T-cell diversity associated with colitis in T-cell receptor alpha mutant mice requires a T helper 2 environment." Gastroenterology.. 2000 Oct; 119(4):983-95.
2000 Jul
Saubermann LJ, Beck P, De Jong YP, Pitman RS, Ryan MS, Kim HS, Exley M, Snapper S, Balk SP, Hagen SJ, Kanauchi O, Motoki K, Sakai T, Terhorst C, Koezuka Y, Podolsky DK, Blumberg RS. "Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice." Gastroenterology.. 2000 Jul; 119(1):119-28.
2000 Mar 15
Muehlhoefer A, Saubermann LJ, Gu X, Luedtke-Heckenkamp K, Xavier R, Blumberg RS, Podolsky DK, MacDermott RP, Reinecker HC. "Fractalkine is an epithelial and endothelial cell-derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa." The Journal of immunology : official journal of the American Association of Immunologists.. 2000 Mar 15; 164(6):3368-76.
2000
Saubermann, LJ. "pANCA--Is This Your Final Answer?". Inflammatory Bowel Diseases (selected summaries). 2000; 6(4): 332-333. Link
1999 Jun 15
Blumberg RS, Lencer WI, Zhu X, Kim HS, Claypool S, Balk SP, Saubermann LJ, Colgan SP. "Antigen presentation by intestinal epithelial cells." Immunology letters. 1999 Jun 15; 69(1):7-11.
1999
Saubermann, LJ: Probert, CSJ; Christ, AD; Chott, A; Turner, JR, Stevens, AC; BAlk, SP; Blumberg, RS. "Evidence of T cell receptor B-chain patterns in inflammatory and non-inflammatory bowel disease states." Amer Journ of Physiology. 1999; 276: G613-G621. Link
1999
Saubermann, LJ.; Wolf, J. "Mesalamine: Safe at First Look". Inflammatory Bowel Diseases (selected summaries). 1999; 5(2): 148-149. Link
1999
Blumberg RS, Saubermann LJ, Strober W. "Animal models of mucosal inflammation and their relation to human inflammatory bowel disease." Current opinion in immunology. 1999 11(6):648-56.
1998 Jun
Omata F, Itoh T, Shibayama Y, Ide H, Takahashi H, Ueno F, Saubermann LJ, Matsuzaki S. "Duodenal variceal bleeding treated with a combination of endoscopic ligation and sclerotherapy." Endoscopy. 1998 Jun; 30(5):S62-3.
1998
Probert, CSJ.; Aitken, EW.; Saubermann, LJ.; Balk, SP.; Blumberg, RS. "T-Cell Receptor Usage in the Intestine." Chem Immunology. 1998; 71: 27-39. Link
1997 Feb 15
Probert CS, Christ AD, Saubermann LJ, Turner JR, Chott A, Carr-Locke D, Balk SP, Blumberg RS. "Analysis of human common bile duct-associated T cells: evidence for oligoclonality, T cell clonal persistence, and epithelial cell recognition." The Journal of immunology : official journal of the American Association of Immunologists.. 1997 Feb 15; 158(4):1941-8.
1996 Oct 1
Probert CS, Chott A, Turner JR, Saubermann LJ, Stevens AC, Bodinaku K, Elson CO, Balk SP, Blumberg RS. "Persistent clonal expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease." The Journal of immunology : official journal of the American Association of Immunologists.. 1996 Oct 1; 157(7):3183-91.

Books

2006
Saubermann LJ; Farraye FA. "Ulcerative Colitis". Therapies of Digestive Disorders, second edition. M.W. Wolfe, et al, Eds.. : Elsevier Publishers, 2006.
2003
Saubermann, LJ and Farraye, FA.. "Inflammatory Bowel Disease". Cecil Essentials of Medicine. Andreoli TE et al.. Philadelphia: W.B. Saunders Company, 2003.
2000
Saubermann, LJ and Blumberg RS. "Immunological Aspects of Gastroenterology". Molecular Immunology of Mucosal T Cells. : Kluwer Academic Press, 2000.
2000
Saubermann, LJ and Blumberg, RS.. "Molecular Immunology of Mucosal T Cells". Immunological Aspects of Gastroenterology. : Kluwer Academic Press, 2000.
1998
Saubermann, LJ and Wolf, J.. "Reproduction and Inflammatory Bowel Disese.". Inflammatory Bowel Disease: A Guide for Patients and Their Families. Hanauer SB, Kirsner JB. : Lippincott-Raven Press, 1998. 67-77
1998
Probert CSJ, Aitken EW, Saubermann LJ, Balk SP, Blumberg RS.. "T-Cell Receptor Usage in the Intestine". Chem Immunology. : Chem Immunology, 1998. 27-39