2009 Jun 20
Zhu AX, Sahani DV, Duda DG, di Tomaso E, Ancukiewicz M, Catalano OA, Sindhwani V, Blaszkowsky LS, Yoon SS, Lahdenranta J, Bhargava P, Meyerhardt J, Clark JW, Kwak EL, Hezel AF, Miksad R, Abrams TA, Enzinger PC, Fuchs CS, Ryan DP, Jain RK. "Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study." Journal of clinical oncology : official journal of the American
Society of Clinical Oncology. 2009 Jun 20; 27(18):3027-35. Epub 2009 May 26.
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2009 May
Plentz R, Park JS, Rhim AD, Abravanel D, Hezel AF, Sharma SV, Gurumurthy S, Deshpande V, Kenific C, Settleman J, Majumder PK, Stanger BZ, Bardeesy N. "Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma." Gastroenterology. 2009 May 0; 136(5):1741-9.e6. Epub 2009 Jan 14.
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2009 Jan 10
Wolpin BM, Hezel AF, Abrams T, Blaszkowsky LS, Meyerhardt JA, Chan JA, Enzinger PC, Allen B, Clark JW, Ryan DP, Fuchs CS. "Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer." Journal of clinical oncology : official journal of the American
Society of Clinical Oncology. 2009 Jan 10; 27(2):193-8. Epub 2008 Dec 01.
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2008 Nov 24
Hezel AF, Bardeesy N. "LKB1; linking cell structure and tumor suppression." Oncogene. 2008 Nov 24; 27(55):6908-19.
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2008 Sep
Hezel AF, Bardeesy N. "Prognostic markers in pancreatic ductal adenocarcinomas." Cancer biology & therapy. 2008 Sep 0; 7(9):1360-1. Epub 2008 Sep 06.
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2008 Apr
Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA. "Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms." Molecular and cellular biology. 2008 Apr 0; 28(7):2414-25. Epub 2008 Jan 28.
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2008 Apr
Perera SA, Maser RS, Xia H, McNamara K, Protopopov A, Chen L, Hezel AF, Kim CF, Bronson RT, Castrillon DH, Chin L, Bardeesy N, Depinho RA, Wong KK. "Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer." Carcinogenesis. 2008 Apr 0; 29(4):747-53. Epub 2008 Feb 17.
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2008 Apr
Hezel AF, Zhu AX. "Systemic therapy for biliary tract cancers." The oncologist. 2008 Apr 0; 13(4):415-23.
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2008 Jan 1
Gurumurthy S, Hezel AF, Sahin E, Berger JH, Bosenberg MW, Bardeesy N. "LKB1 deficiency sensitizes mice to carcinogen-induced tumorigenesis." Cancer research. 2008 Jan 1; 68(1):55-63.
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2008
Kimmelman AC, Hezel AF, Aguirre AJ, Zheng H, Paik JH, Ying H, Chu GC, Zhang JX, Sahin E, Yeo G, Ponugoti A, Nabioullin R, Deroo S, Yang S, Wang X, McGrath JP, Protopopova M, Ivanova E, Zhang J, Feng B, Tsao MS, Redston M, Protopopov A, Xiao Y, Futreal PA, Hahn WC, Klimstra DS, Chin L, DePinho RA. "Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer." Proceedings of the National Academy of Sciences of the United States
of America. 2008 105(49):19372-7. Epub 2008 Dec 02.
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2007 Jul 1
Chu GC, Kimmelman AC, Hezel AF, DePinho RA. "Stromal biology of pancreatic cancer." Journal of cellular biochemistry. 2007 Jul 1; 101(4):887-907.
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2007 Jun
Hezel AF, Ryan DP. "Emerging therapies for colorectal cancer." Expert opinion on investigational drugs. 2007 Jun 0; 16(6):867-76.
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2007
Geyer N, Bartges JW, Kirk CA, Cox S, Hezel A, Moyers T, Hayes J. "Influence of prednisolone on urinary calcium oxalate and struvite relative supersaturation in healthy young adult female domestic shorthaired cats." Veterinary therapeutics : research in applied veterinary
medicine. 2007 8(4):239-46.
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2006 Nov 15
Bardeesy N, Cheng KH, Berger JH, Chu GC, Pahler J, Olson P, Hezel AF, Horner J, Lauwers GY, Hanahan D, DePinho RA. "Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer." Genes & development. 2006 Nov 15; 20(22):3130-46.
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2006 May 15
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA. "Genetics and biology of pancreatic ductal adenocarcinoma." Genes & development. 2006 May 15; 20(10):1218-49.
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2006 Apr 11
Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. "Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse." Proceedings of the National Academy of Sciences of the United States
of America. 2006 Apr 11; 103(15):5947-52. Epub 2006 Apr 03.
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2006 Mar 30
Ji H, Houghton AM, Mariani TJ, Perera S, Kim CB, Padera R, Tonon G, McNamara K, Marconcini LA, Hezel A, El-Bardeesy N, Bronson RT, Sugarbaker D, Maser RS, Shapiro SD, Wong KK. "K-ras activation generates an inflammatory response in lung tumors." Oncogene. 2006 Mar 30; 25(14):2105-12.
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2005 Mar
Hezel AF, Bardeesy N, Maser RS. "Telomere induced senescence: end game signaling." Current molecular medicine. 2005 Mar 0; 5(2):145-52.
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2002 Sep 12
Bardeesy N, Sinha M, Hezel AF, Signoretti S, Hathaway NA, Sharpless NE, Loda M, Carrasco DR, DePinho RA. "Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation." Nature. 2002 Sep 12; 419(6903):162-7.
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2001 Mar
Bardeesy N, Bastian BC, Hezel A, Pinkel D, DePinho RA, Chin L. "Dual inactivation of RB and p53 pathways in RAS-induced melanomas." Molecular and cellular biology. 2001 Mar 0; 21(6):2144-53.
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1999 Feb 4
Giese H, Dollé ME, Hezel A, van Steeg H, Vijg J. "Accelerated accumulation of somatic mutations in mice deficient in the nucleotide excision repair gene XPA." Oncogene. 1999 Feb 4; 18(5):1257-60.
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