Pharmacology & Physiology
A Message from the Chair:
The Department of Pharmacology and Physiology consists of faculty, fellows and students who are dedicated to cutting-edge scientific research, in order to work towards a better understanding of how the human body functions and to alleviate human diseases. The faculty is composed of distinguished scientists who are international leaders in the fields of cell signaling, G-proteins and ion channels, mitochondria and mechanisms of cell death, cardiovascular diseases and vascular biology, neurodegeneration and drugs of abuse, and integrative neurosciences. The department promotes a strong training program for both graduate students and post-doctoral fellows, and many of our graduates have gone on to become leaders in academia, industry and government. The University of Rochester is now in the process of implementing a new strategic plan, which emphasizes a number of research fields, including neuromedicine and cardiovascular biology, that fit well with the Department’s research interests. The Department is enthusiastic about being a part of this plan and the anticipated growth in the University’s research enterprise, as we aim to be one of the finest medical centers in the world.
A. William Tank, Ph.D.
Lewis Pratt Ross Professor of Pharmacology and Physiology and Chair
Paper of the Week, The Journal of Biological Chemistry
Kamil J. Alzayady, Ph.D.
A journal article by Kamil J. Alzayady, Larry E. Wagner II, Rahul Chandrasekhar, Alina Monteagudo, Ronald Godiska, Gregory G. Tall, Suresh K. Joseph, and David I. Yule was selected as a Paper of the Week by The Journal of Biological Chemistry.
Alzayady KJ, Wagner LE 2nd, Chandrasekhar R, Monteagudo AM, Godiska R, Tall GG, Joseph SK, and Yule DI. (2013) Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits. J Biol Chem. 288:29772-29784. (Paper of the Week)
2013 Convocation Award
|Dr. Robert T. Dirksen was selected as the 2013 recipient of the Excellence in Postdoctoral Mentoring Award. This award is presented to a postdoctoral mentor who shows dedication to postdoctoral trainees, as well as evidence of contributing significantly to their career development and professional advancement and was presented at the School of Medicine and Dentistry Convocation, September 12, 2013.|
Faculty Focus Article
Dr. Alan V. Smrcka's recent article, "Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy," published in Cell was the subject of a faculty focus article published in Inside URMC.
Get In Touch
Department of Pharmacology and Physiology
University of Rochester Medical Center
601 Elmwood Avenue, Box 711
Rochester, NY 14642
Phone, (585) 275-1679
Fax, (585) 273-2652
Bansaghi S, Golenar T, Madesh M, Csordas G, Ramachandrarao S, Sharma K, Yule DI, Joseph SK, Hajnoczky G. (2014) Isoform-and species-specific control of IP3 receptors by reactive oxygen species. J Biol Chem. [Epub ahead of print]
Gildner CD, Roy DC, Farrar CS, Hocking DC. (2014) Opposing effects of collagen I and vitronectin on fibronectin fibril structure and function. Matrix Biol. [Epub ahead of print]
Goonasekera SA, Davis J, Kwong JQ, Accornero F, Wei-Lapierre L, Sargent MA, Dirksen RT, Molkentin JD. (2014) Enhanced Ca2+ influx from STIM1-Orai1 induces muscle pathology in mouse models of muscular dystrophy. Hum Mol Genet. [Epub ahead of print]