Pharmacology & Physiology
A Message from the Chair:
The Department of Pharmacology and Physiology consists of faculty, fellows and students who are dedicated to cutting-edge scientific research, in order to work towards a better understanding of how the human body functions and to alleviate human diseases. The faculty is composed of distinguished scientists who are international leaders in the fields of cell signaling, G-proteins and ion channels, mitochondria and mechanisms of cell death, cardiovascular diseases and vascular biology, neurodegeneration and drugs of abuse, and integrative neurosciences. The department promotes a strong training program for both graduate students and post-doctoral fellows, and many of our graduates have gone on to become leaders in academia, industry and government. The University of Rochester is now in the process of implementing a new strategic plan, which emphasizes a number of research fields, including neuromedicine and cardiovascular biology, that fit well with the Department’s research interests. The Department is enthusiastic about being a part of this plan and the anticipated growth in the University’s research enterprise, as we aim to be one of the finest medical centers in the world.
A. William Tank, Ph.D.
Lewis Pratt Ross Professor of Pharmacology and Physiology and Chair
Faculty Focus Article
Dr. Alan V. Smrcka's recent article, "Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy," published in Cell was the subject of a faculty focus article published in Inside URMC.
Cover Art for Tissue Engineering, Part B: Reviews
Daniel C. Roy, Ph.D.
An image by Dr. Denise C. Hocking and Dr. Daniel C. Roy was selected as cover art for Tissue Engineering, Part B: Reviews, Volume 19, Number 1, February 2013. This is a human mesenchymal stem cells adherent to a recombinant fibronectin mimetic substrate polymerize an endogenous fibronectin matrix (green) using α5β1 integrins (red).
Get In Touch
Department of Pharmacology and Physiology
University of Rochester Medical Center
601 Elmwood Avenue, Box 711
Rochester, NY 14642
Phone, (585) 275-1679
Fax, (585) 273-2652
Smrcka AV. (2013) Molecular targeting of Gα and Gβγ subunits: a potential approach for cancer therapeutics. Trends Pharmacol. Sci. Epub ahead of print]
Sumagin R, and Sarelius IH (2013) Emerging Understanding of Roles for Arterioles in Inflammation. Microcirculation [Epub ahead of print]
Thompson JL, and Shuttleworth TJ. (2013) Molecular basis of activation of the arachidonate-regulated ARC channel, a store-independent Orai channel, by plasma membrane STIM1. J. Physiol. [Epub ahead of print]