Pharmacology & Physiology
A Message from the Chair:
The Department of Pharmacology and Physiology consists of faculty, fellows and students who are dedicated to cutting-edge scientific research, in order to work towards a better understanding of how the human body functions and to alleviate human diseases. The faculty is composed of distinguished scientists who are international leaders in the fields of cell signaling, G-proteins and ion channels, mitochondria and mechanisms of cell death, cardiovascular diseases and vascular biology, neurodegeneration and drugs of abuse, and integrative neurosciences. The department promotes a strong training program for both graduate students and post-doctoral fellows, and many of our graduates have gone on to become leaders in academia, industry and government. The University of Rochester is now in the process of implementing a new strategic plan, which emphasizes a number of research fields, including neuromedicine and cardiovascular biology, that fit well with the Department’s research interests. The Department is enthusiastic about being a part of this plan and the anticipated growth in the University’s research enterprise, as we aim to be one of the finest medical centers in the world.
A. William Tank, Ph.D.
Lewis Pratt Ross Professor of Pharmacology and Physiology and Chair
UR Research in the News: Research Connections, October 3, 2014
Diane Dalecki, Professor of Biomedical Engineering and Director of the Rochester Center for Biomedical Ultrasound, and Denise C. Hocking, Associate Professor of Pharmacology & Physiology, have received a $2 million grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) for their project titled "Ultrasound standing wave fields for vascular engineering." The goal of this 4-year project is to advance a novel ultrasound technology to fabricate complex, functional microvascular networks within three-dimensional engineered constructs. Collaborators on this project are Maria Helguera, Associate Professor of Imaging Sciences at RIT; Ingrid Sarelius, Professor of Pharmacology and Physiology; and Angela Glading, Assistant Professor of Pharmacology and Physiology. New, versatile vascularization strategies are needed to produce small-scale 3D tissue models and are critical for the fabrication of large-scale engineered tissues. The noninvasive capacity of ultrasound also enables innovative capabilities for fabricating microvessel networks within hydrogels injected within tissues. The successful completion of this project will provide new tools for tissue engineering and for a variety of clinical reconstructive and vascular surgery applications. Click here for a video about these researchers' use of ultrasound for tissue engineering.
Get In Touch
Department of Pharmacology and Physiology
University of Rochester Medical Center
601 Elmwood Avenue, Box 711
Rochester, NY 14642
Phone, (585) 275-1679
Fax, (585) 273-2652
Le NT, Takei Y, Izawa-Ishizawa Y, Heo KS, Lee H, Smrcka AV, Miller BL, Ko KA, Ture S, Morrell C, Fujiwara K, Akaike M, Abe JI. (2014) Identification of Activators of ERK5 Transcriptional Activity by High-Throughput Screening and the Role of Endothelial ERK5 in Vasoprotective Effects Induced by Statins and Antimalarial Agents J Immunol. 193 (7):3803-3815.