Faculty Department Lab Affiliation(s) Interests
J. Scott. Butler, Ph.D.  
Associate Professor of Microbiology & Immunology Butler Lab Roles of ribonuclease toxins in the control of persistence and latency in pathogenic bacteria.
Gloria Culver, Ph.D.  
Chair and Professor of Biology Culver Lab Assembly of the E. coli 30S ribosomal subunit, which is essential for cellular growth, so as to understand how infections might be controlled through selective inhibition of specific assembly control points.
Paul Dunman, Ph.D.  
Associate Professor of Microbiology & Immunology Dunman Lab Antimicrobial drug discovery using pathogenic Staphylococcus aureus and Acinetobacter baumannii: exploiting components of the bacterial RNA metabolism machinery; characterizing prokaryotic ribonucleases; understanding the impact of the host environment on antibiotic resistance and virulence factor expression.
Thomas Eickbush, Ph.D.  
Professor of Biology Eickbush Lab Retrotransposable elements, protein: RNA and protein: DNA interactions, sequence specific endonucleases.
Dmitri N.. Ermolenko, Ph.D.  
Assistant Professor of Biochemistry & Biophysics Ermolenko Lab Structural dynamics of the ribosome and ribosomal ligands during proteins synthesis, regulation of protein synthesis by mRNA structure in normal and diseased cells, and mechanisms of antibiotic action.
Dragony Fu, Ph.D.  
Assistant Professor of Biology Fu Lab Nucleic acid modification and repair mechanisms linked to neurodevelopmental disorders, mitochondrial diseases, and cancer.
Elizabeth Grayhack, Ph.D.  
Associate Professor of Biochemistry & Biophysics Grayhack Lab Role of the genetic code in regulating protein synthesis and mRNA metabolism in Saccharomyces cerevisiae.
Clara L.. Kielkopf, Ph.D.  
Associate Professor of Biochemistry & Biophysics Kielkopf Lab Splicing defects in hematologic malignancies; roles of human pre-mRNA splicing factors in HIV-1 infectivity; development of engineered splicing factors for correction of splicing defects; splice sites and their associated proteins as therapeutic targets.
Xin Zhiguo. Li, Ph.D.  
Assistant Professor of Biochemistry & Biophysics Xin Li Lab Small non-coding RNA regulation in germ cells; meiosis; male infertility.
Lynne Maquat, Ph.D.  

Professor of Biochemistry & Biophysics Maquat Lab RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases.
Luis Martinez-Sobrido, Ph.D.  
Associate Professor of Microbiology & Immunology Martinez-Sobrido Lab Molecular biology, immunology, and pathogenesis of negative-stranded (Influenza viruses, Respiratory Syncytial Virus, Human Metapneumovirus, arenavirus, Thogoto virus, Ebola virus, Crimean Congo Hemorrhagic Fever virus) and positive-stranded (Dengue virus, SARS coronavirus, Mouse Hepatitis virus) RNA and DNA (human cytomegalovirus and vaccinia) viruses.
David H.. Mathews, M.D., Ph.D.  
Associate Director

Associate Professor of Biochemistry & Biophysics Mathews Lab Computational biology of RNA, including structure prediction, molecular dynamics, and genomics.
Jim Miller, Ph.D.  
Professor of Microbiology & Immunology Jim Miller Lab ,
Program for Advanced Immune Bioimaging
Molecular and cellular events that regulate T cell signaling and activation
Eric Phizicky, Ph.D.  
Professor of Biochemistry & Biophysics Phizicky Lab tRNA biogenesis, function and quality control; intellectual disability due to deficiencies in tRNA modifications.
Gaurav Sharma, Ph.D.  
Professor of Electrical & Computer Engineering Sharma Lab Computational biology of RNA; RNA comparative sequence analysis; RNA structure prediction; analysis of HIV RNA genomes.
Harold C.. Smith, Ph.D.  
Professor of Biochemistry & Biophysics Smith Lab RNA regulation of innate immune modulators and small molecule inhibitors of HIV RNA-binding proteins.
Charles A.. Thornton, M.D.  
Professor of Neurology Thornton Lab Neurogenetic disorders, including myotonic dystrophy; therapeutics, including antisense approaches.
Douglas H.. Turner, Ph.D.  
Professor of Chemistry Turner Lab Biophysical chemistry of RNA folding/stacking using NMR; RNA-targeted therapeutics (e.g., pseudoknot-regulated influenza A RNA translation; 3’-splice site and other regulatory intronic structures in influenza A).
Joseph E.. Wedekind, Ph.D.  
Professor of Biochemistry & Biophysics Wedekind Lab Structure and function analysis of gene regulation by riboswitches and microRNAs as a basis for therapeutic development.
Yi-Tao Yu, Ph.D.  
Professor of Biochemistry & Biophysics Yu Lab RNA modification; pre-mRNA splicing; snRNP biogenesis; telomerase RNA modification and aging; nonsense-disease therapeutics.