Flaum Eye Institute / Research / Labs / Feldon Lab / Publications Recent Publications Dogra NRedmond BVLilley SJohnson BALam BLTamhankar MFeldon SEFahrenthold BYang JHuxlin KRCavanaugh MR Vision-related quality of life after unilateral occipital stroke.; Brain and behavior; Vol 14(7), pp. e3582. 2024 Jul. Fahrenthold BKCavanaugh MRTamhankar MLam BLFeldon SEJohnson BAHuxlin KR Training in Cortically Blinded Fields Appears to Confer Patient-Specific Benefit Against Retinal Thinning.; Investigative ophthalmology & visual science; Vol 65(4), pp. 29. 2024 Apr 01. Fahrenthold BKCavanaugh MRTamhankar MLam BLFeldon SEJohnson BAHuxlin KR Training in cortically-blind fields confers patient-specific benefit against retinal thinning after occipital stroke.; medRxiv : the preprint server for health sciences. 2023 Dec 20. Kahaly GJDolman PJWolf JGiers BCElflein HMJain APSrinivasan AHadjiiski LJordan DBradley EAStan MNEckstein APitz SVorländer CWester STNguyen JTucker NSales-Sanz MFeldon SENelson CCHardy IAbia-Serrano MTedeschi PJanes JMXu JVue PMacias WLDouglas RS Proof-of-Concept and Randomized, Placebo-Controlled Trials of an Fcrn Inhibitor, Batoclimab, for Thyroid Eye Disease.; The Journal of clinical endocrinology and metabolism. 2023 Jun 30. Valencia WEMason SSBrunstetter TJSargsyan AESchaefer CMTarver WJVan Baalen MGGibson CRLee AGDanilichev SNHinton PVMakarov IAMatveev VPStern CHTaniguchi-Shinojima AFeldon SE Evaluation of Optic Disc Edema in Long-Duration Spaceflight Crewmembers Using Retinal Photography.; Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2023 Jan 04. Wang VHeffer ARoztocil EFeldon SELibby RTWoeller CFKuriyan AE TNF-α and NF-κB signaling play a critical role in cigarette smoke-induced epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy.; PloS one; Vol 17(9), pp. e0271950. 2022 Sep 01. Hammond CLRoztocil EGupta VFeldon SEWoeller CF More than Meets the Eye: The Aryl Hydrocarbon Receptor is an Environmental Sensor, Physiological Regulator and a Therapeutic Target in Ocular Disease.; Frontiers in toxicology; Vol 4. 2022. Moss HECao JWasi MFeldon SEShahidi M Variability of Retinal Vessel Tortuosity Measurements Using a Semiautomated Method Applied to Fundus Images in Subjects With Papilledema.; Translational vision science & technology; Vol 10(14). 2021 Dec 01. Quillen DALee PPMiller JWFeldon SE Re: Fairless et al.: Ophthalmology departments remain among the least diverse clinical departments at United States medical schools (Ophthalmology. 2021;128:1129-1134).; Ophthalmology. 2021 Nov 06. Gupta VHammond CLRoztocil EGonzalez MOFeldon SEWoeller CF Thinking inside the box: Current insights into targeting orbital tissue remodeling and inflammation in thyroid eye disease.; Survey of ophthalmology. 2021 Sep 03. Hammond CLRoztocil EGonzalez MOFeldon SEWoeller CF MicroRNA-130a Is Elevated in Thyroid Eye Disease and Increases Lipid Accumulation in Fibroblasts Through the Suppression of AMPK.; Investigative ophthalmology & visual science; Vol 62(1). 2021 Jan 04. Cavanaugh MRBlanchard LMMcDermott MLam BLTamhankar MFeldon SE Efficacy of Visual Retraining in the Hemianopic Field After Stroke: Results of a Randomized Clinical Trial.; Ophthalmology. 2020 Nov 23. Saionz ELFeldon SEHuxlin KR Rehabilitation of cortically induced visual field loss.; Current opinion in neurology. 2020 Nov 20. Heffer AWang VSridhar JFeldon SELibby RTWoeller CFKuriyan AE A Mouse Model of Proliferative Vitreoretinopathy Induced by Intravitreal Injection of Gas and RPE Cells.; Translational vision science & technology; Vol 9(7). 2020 Jun. Roztocil EHammond CLGonzalez MOFeldon SEWoeller CF The aryl hydrocarbon receptor pathway controls matrix metalloproteinase-1 and collagen levels in human orbital fibroblasts.; Scientific reports; Vol 10(1). 2020 May 21. Moss HEHollar RAFischer WSFeldon SE Retinal vessel diameter changes after 6 months of treatment in the Idiopathic Intracranial Hypertension Treatment Trial.; The British journal of ophthalmology. 2020 Jan 16. Heffer AMWang VLibby RTFeldon SEWoeller CFKuriyan AE Salinomycin inhibits proliferative vitreoretinopathy formation in a mouse model.; PloS one; Vol 15(12). 2020. Woeller CFRoztocil EHammond CFeldon SE TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts.; Investigative ophthalmology & visual science; Vol 60(13). 2019 Oct 01. Heffer AMProaño JRoztocil EPhipps RPFeldon SEHuxlin KRSime PJLibby RTWoeller CFKuriyan AE The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology.; PloS one; Vol 14(9). 2019. Hammond CLRoztocil EPhipps RPFeldon SEWoeller CF Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor.; PloS one; Vol 14(9). 2019. Sheils CRFischer WSHollar RABlanchard LMFeldon SE The Relationship Between Optic Disc Volume, Area, and Frisén Score in Patients With Idiopathic Intracranial Hypertension.; American journal of ophthalmology; Vol 195. 2018 Jan. Ramchandran RSFeldon SEOwsley C Current Shortcomings of Camera Screening.; JAMA internal medicine; Vol 177(10). 2017 Oct 01. Kupersmith MJSibony PAFeldon SEWang JKGarvin MKardon R The Effect of Treatment of Idiopathic Intracranial Hypertension on Prevalence of Retinal and Choroidal Folds.; American journal of ophthalmology; Vol 176. 2017 Apr. Woeller CFRoztocil EHammond CLFeldon SEPhipps RP The Aryl Hydrocarbon Receptor and Its Ligands Inhibit Myofibroblast Formation and Activation: Implications for Thyroid Eye Disease.; The American journal of pathology; Vol 186(12). 2016 Dec. Bingham CMSivak-Callcott JAGurka MJNguyen JHogg JPFeldon SEFay ASeah LLStrianese DDurairaj VDUddin JDevoto MHHarris MSaunders JOsaki THLooi ATeo LDavies BWElefante AShen SRealini TFischer WKazim M Axial Globe Position Measurement: A Prospective Multicenter Study by the International Thyroid Eye Disease Society.; Ophthalmic plastic and reconstructive surgery; Vol 32(2). 2016 Mar. Sibony PAKupersmith MJFeldon SEKardon R Author Response: Choroidal Folds in Astronauts.; Investigative ophthalmology & visual science; Vol 57(2). 2016 Feb. Sibony PAKupersmith MJFeldon SEWang JKGarvin M Retinal and Choroidal Folds in Papilledema.; Investigative ophthalmology & visual science; Vol 56(10). 2015 Sep. Fischer WSWall MMcDermott MPKupersmith MJFeldon SE Photographic Reading Center of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT): Methods and Baseline Results.; Investigative ophthalmology & visual science; Vol 56(5). 2015 May. Woeller CFO'Loughlin CWPollock SJThatcher THFeldon SEPhipps RP Thy1 (CD90) controls adipogenesis by regulating activity of the Src family kinase, Fyn.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 29(3). 2015 Mar. Woeller CFO'Loughlin CWRoztocil EFeldon SEPhipps RP Salinomycin and other polyether ionophores are a new class of antiscarring agent.; The Journal of biological chemistry; Vol 290(6). 2015 Feb 6. Spinelli SLXi XMcMillan DHWoeller CFRichardson MECavet MEZhang JZFeldon SEPhipps RP Mapracorat, a selective glucocorticoid receptor agonist, upregulates RelB, an anti-inflammatory nuclear factor-kappaB protein, in human ocular cells.; Experimental eye research; Vol 127. 2014 Oct. Friedman DIMcDermott MPKieburtz KKupersmith MStoutenburg AKeltner JLFeldon SESchron ECorbett JJWall M The idiopathic intracranial hypertension treatment trial: design considerations and methods.; Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society; Vol 34(2). 2014 Jun. Wall MKupersmith MJKieburtz KDCorbett JJFeldon SEFriedman DIKatz DMKeltner JLSchron EBMcDermott MP The idiopathic intracranial hypertension treatment trial: clinical profile at baseline.; JAMA neurology; Vol 71(6). 2014 Jun. Wall MMcDermott MPKieburtz KDCorbett JJFeldon SEFriedman DIKatz DMKeltner JLSchron EBKupersmith MJ Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial.; JAMA; Vol 311(16). 2014 Feb. Kuriyan AEWoeller CFO'Loughlin CWPhipps RPFeldon SE Orbital fibroblasts from thyroid eye disease patients differ in proliferative and adipogenic responses depending on disease subtype.; Investigative ophthalmology & visual science; Vol 54(12). 2013 Nov. Miller BKhalifa YFeldon SEFriedman DI Lemierre syndrome causing bilateral cavernous sinus thrombosis.; Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society; Vol 32(4). 2012 Dec. Kuriyan AELehmann GMKulkarni AAWoeller CFFeldon SEHindman HBSime PJHuxlin KRPhipps RP Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring.; Experimental eye research; Vol 94(1). 2012 Jan. Abazari AChak GFeldon SE Reply re: "Sinus opacification associated with exacerbation of thyroid eye disease".; Ophthalmic plastic and reconstructive surgery; Vol 27(4). 2011 Jul. Chak GWang HZFeldon SE Coup de sabre presenting with worsening diplopia and enophthalmos.; Ophthalmic plastic and reconstructive surgery; Vol 27(4). 2011 Jul. Xi XMcMillan DHLehmann GMSime PJLibby RTHuxlin KRFeldon SEPhipps RP Ocular fibroblast diversity: implications for inflammation and ocular wound healing.; Investigative ophthalmology & visual science; Vol 52(7). 2011 Jun. Guo NWoeller CFFeldon SEPhipps RP Peroxisome proliferator-activated receptor gamma ligands inhibit transforming growth factor-beta-induced, hyaluronan-dependent, T cell adhesion to orbital fibroblasts.; The Journal of biological chemistry; Vol 286(21). 2011 May 27. Lehmann GMXi XKulkarni AAOlsen KCPollock SJBaglole CJGupta SCasey AEHuxlin KRSime PJFeldon SEPhipps RP The aryl hydrocarbon receptor ligand ITE inhibits TGFβ1-induced human myofibroblast differentiation.; The American journal of pathology; Vol 178(4). 2011 Apr. Lehmann GMWoeller CFPollock SJO'Loughlin CWGupta SFeldon SEPhipps RP Novel anti-adipogenic activity produced by human fibroblasts.; American journal of physiology. Cell physiology; Vol 299(3). 2010 Sep. Abazari AChak GFeldon SE Sinus opacification associated with exacerbation of thyroid eye disease.; Ophthalmic plastic and reconstructive surgery; Vol 26(4). 2010 Jul. Guo NBaglole CJO'Loughlin CWFeldon SEPhipps RP Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease.; The Journal of biological chemistry; Vol 285(21). 2010 May 21. Simpson-Haidaris PJPollock SJRamon SGuo NWoeller CFFeldon SEPhipps RP Anticancer Role of PPARgamma Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes.; PPAR research; Vol 2010. 2010. Perry JDFeldon SE Rationale for radiotherapy in thyroid eye disease.; American journal of ophthalmology; Vol 148(6). 2009 Dec. Williams ZRHurley PEAltiparmak UEFeldon SEArnold GLEggenberger EMejico LJ Late onset optic neuropathy in methylmalonic and propionic acidemia.; American journal of ophthalmology; Vol 147(5). 2009 May. Stasi KRamchandran RSRao NAFeldon SEDiLoreto DA Retinal arteriolar spasm during transient monocular visual loss in eosinophilic vasculitis.; Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society; Vol 29(1). 2009 Mar. Kuriyan AEPhipps RPFeldon SE The eye and thyroid disease.; Current opinion in ophthalmology; Vol 19(6). 2008 Nov. Feldon SE Optic neuritis and the risk of multiple sclerosis--what can we learn from a brain MRI scan?; Nature clinical practice. Neurology; Vol 4(10). 2008 Oct. Scherer RWFeldon SELevin LLangenberg PKatz JKeyl PMWilson PDKelman SEDickersin K Visual fields at follow-up in the Ischemic Optic Neuropathy Decompression Trial: evaluation of change in pattern defect and severity over time.; Ophthalmology; Vol 115(10). 2008 Oct. Lehmann GMFeldon SESmith TJPhipps RP Immune mechanisms in thyroid eye disease.; Thyroid : official journal of the American Thyroid Association; Vol 18(9). 2008 Sep. Kuriyan AEPhipps RPO'Loughlin CWFeldon SE Improvement of thyroid eye disease following treatment with the cyclooxygenase-2 selective inhibitor celecoxib.; Thyroid : official journal of the American Thyroid Association; Vol 18(8). 2008 Aug. Lehmann GMGarcia-Bates TMSmith TJFeldon SEPhipps RP Regulation of Lymphocyte Function by PPARgamma: Relevance to Thyroid Eye Disease-Related Inflammation.; PPAR research; Vol 2008. 2008. Cruz OARoper-Hall GFeldon SE Relaxed muscle positioning technique.; Ophthalmology; Vol 114(11). 2007 Nov. Zoumalan CICockerham KPTurbin REVolpe NJKazim MDouglas RSFeldon SE Efficacy of corticosteroids and external beam radiation in the management of moderate to severe thyroid eye disease.; Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society; Vol 27(3). 2007 Sep. Feldon SE Visual outcomes comparing surgical techniques for management of severe idiopathic intracranial hypertension.; Neurosurgical focus; Vol 23(5). 2007. Feldon SEO'loughlin CWRay DMLandskroner-Eiger SSeweryniak KEPhipps RP Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytes.; The American journal of pathology; Vol 169(4). 2006 Oct. Baglole CJRay DMBernstein SHFeldon SESmith TJSime PJPhipps RP More than structural cells, fibroblasts create and orchestrate the tumor microenvironment.; Immunological investigations; Vol 35(3-4). 2006. Feldon SELevin LScherer RWArnold AChung SMJohnson LNKosmorsky GNewman SAKatz JLangenberg PWilson PDKelman SEDickersin K Development and validation of a computerized expert system for evaluation of automated visual fields from the Ischemic Optic Neuropathy Decompression Trial.; BMC ophthalmology; Vol 6. 2006. Feldon SLevin LScherer RArnold AChung SMJohnson LKosmorsky GNewman SKatz JLangenberg PWilson PDKelman SEKickersin K Development and Validation of a Computerized Expert System for Evaluation of Automated Visual Feilds From the Ischemic Optic Neuopathy Decompression Trial.; Biomedical Central Ophthalmology. 2006 Jan 01. Feldon SEPark DJO'Loughlin CWNguyen VTLandskroner-Eiger SChang DThatcher THPhipps RP Autologous T-lymphocytes stimulate proliferation of orbital fibroblasts derived from patients with Graves' ophthalmopathy.; Investigative ophthalmology & visual science; Vol 46(11). 2005 Nov. Feldon SPark DJO'Loughlin CWNguyen VTLandskroner-Eiger SChang DThatcher THPhipps RP Autologous T-lymphocytes stimulate proliferation of orbital fibroblasts derived from patients with Graves' ophthalmopathy; IOVS; Vol 46, pp. 3913-21. 2005 Jan 01. Baglole CJReddy SYPollock SJFeldon SESime PJSmith TJPhipps RP Isolation and phenotypic characterization of lung fibroblasts.; Methods in molecular medicine; Vol 117. 2005. Turner CKBlieden TMSmith TJFeldon SEFoster DCSime PJPhipps RP A novel ELISpot method for adherent cells.; Journal of immunological methods; Vol 291(1-2). 2004 Aug. Kim JMLaBree LLevin LFeldon SE The relation of Graves' ophthalmopathy to circulating thyroid hormone status.; The British journal of ophthalmology; Vol 88(1). 2004 Jan. Feldon SE Computerized expert system for evaluation of automated visual fields from the Ischemic Optic Neuropathy Decompression Trial: methods, baseline fields, and six-month longitudinal follow-up.; Transactions of the American Ophthalmological Society; Vol 102. 2004. Koumas LSmith TJFeldon SBlumberg NPhipps RP Thy-1 expression in human fibroblast subsets defines myofibroblastic or lipofibroblastic phenotypes.; The American journal of pathology; Vol 163(4). 2003 Oct. Schmitt NJGrover DAFeldon SE The Eger Macular Stressometer: pilot study.; American journal of ophthalmology; Vol 136(2). 2003 Aug. Feldon SEScherer RWHooper FJKelman SBaker RSGranadier RJKosmorsky GSSeiff SRDickersin K Surgical quality assurance in the Ischemic Optic Neuropathy Decompression Trial (IONDT).; Controlled clinical trials; Vol 24(3). 2003 Jun. Scherer RZhu QLangenberg PFeldon SKelman SDickersin K Comparison of information obtained by operative note abstraction with that recorded on a standardized data collection form.; Surgery; Vol 133(3). 2003 Mar. Crow RWLevin LBLaBree LRubin RFeldon SE Sweep visual evoked potential evaluation of contrast sensitivity in Alzheimer's dementia.; Investigative ophthalmology & visual science; Vol 44(2). 2003 Feb. Quiros PFeldon SF Update on Nonarteritic Anterior Ischemic Optic Neuropathy.; Comprehensive Ophthalmology; Vol 4, pp. 151-158. 2003 Jan 01. Nguyen VTPark DJLevin LFeldon SE Correction of restricted extraocular muscle motility in surgical management of strabismus in graves' ophthalmopathy.; Ophthalmology; Vol 109(2). 2002 Feb. JJ NScherer RLangenberg PKelman SFeldon SKaufman DDickersin K The fellow eye in NAION: Report from the Ischemic Optic Neuropathy Decompression Trial.; Am J of Ophthalmology; Vol 134, pp. 317-28. 2002 Jan 01. Feldon SE Radiation therapy for Graves' ophthalmopathy: trick or treat?; Ophthalmology; Vol 108(9). 2001 Sep. Lee AGTang RAFeldon SEPless MSchiffman JSRubin RMRao N Orbital presentations of giant cell arteritis.; Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie; Vol 239(7). 2001 Jul. Liu NHLaBree LDFeldon SERao NA The epidemiology of giant cell arteritis : a 12-year retrospective study.; Ophthalmology; Vol 108(6). 2001 Jun. Bhagat NGreen RLFeldon SELim JI Exudative retinal detachment in relapsing polychondritis : case report and literature review.; Ophthalmology; Vol 108(6). 2001 Jun. Bhagat NGreen RLFeldon SELim JI Exudative Retinal Detachment in Relapsing Polychondritis: case report and literature review.; Ophthalmol; Vol 108, pp. 1156-9. 2001 Jan 01. Feldon SE Radiation therapy for Graves' ophthalmopathy: trick or treat?; Ophthalmol; Vol 108, pp. 1521-2. 2001 Jan 01. Ischemic Optic Neuropathy Decompression Trial: twenty-four-month update.; Archives of ophthalmology (Chicago, Ill. : 1960); Vol 118(6). 2000 Jun. Chou PIChen CHChen JTWen LYWu DAFeldon SE Alström syndrome with subclinical insulin-resistant diabetes and hepatic dysfunction: a family report.; Journal of pediatric ophthalmology and strabismus; Vol 37(3). 2000 May. Prendiville PChopra MGauderman WJFeldon SE The role of restricted motility in determining outcomes for vertical strabismus surgery in Graves' ophthalmology.; Ophthalmology; Vol 107(3). 2000 Mar. Prendiville PChopra MGauderman WJFeldon SE The Role of Restricted Motility in Determining Outcomes for Vertical Strabismus Surgery in Graves' Ophthalmopathy.; Ophthalmolol; Vol 107, pp. 545-549. 2000 Jan 01. Chou PIChang YSFeldon SEChen JT Optic canal mucocele from anterior clinoid pneumatisation.; The British journal of ophthalmology; Vol 83(11). 1999 Nov. Wang MYSadun FLevin LBLaBree LFeldon SE Occurrence of familial nonarteritic anterior ischemic optic neuropathy in a case series.; Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society; Vol 19(2). 1999 Jun. Feldon SE Anterior ischemic optic neuropathy: trouble waiting to happen.; Ophthalmology; Vol 106(4). 1999 Apr. Wang MYSadun FLevin LBLaBree LFeldon SE Occurrence and clinical profile of familial non-arteritic optic neuropathy.; J Neuro-Ophthalmol; Vol 19, pp. 144-147. 1999 Jan 01. Liu NHLaBree LDFeldon SERao NA The Epidemiology of Giant Cell Arteritis.; Opthalmol; Vol 106, pp. 651-652. 1999 Jan 01. The ischemic optic neuropathy decompression trial (IONDT): design and methods.; Controlled clinical trials; Vol 19(3). 1998 Jun. Tran DBSilverman SEZimmerman KFeldon SE Age-related deterioration of motion perception and detection.; Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie; Vol 236(4). 1998 Apr. Tran DBSilverman SEZimmerman KMFeldon SE Age-related deterioration of motion perception and detection.; Graefe's Arch Clin Exp Ophthalmol; Vol 236, pp. 269-273. 1998 Jan 01. Crawley BScherer RLangenberg PDickersin K Participation in the Ischemic Optic Neuropathy Decompression Trial: sex, race, and age.; Ophthalmic epidemiology; Vol 4(3). 1997 Sep. WuDunn DZimmerman KSadun AAFeldon SE Comparison of visual function in fellow eyes after bilateral nonarteritic anterior ischemic optic neuropathy.; Ophthalmology; Vol 104(1). 1997 Jan. WuDunn DZimmerman KMSadun AAFeldon SE Comparison of visual function in fellow eyes after bilateral non-arteritic anterior ischemic optic neuropathy.; Ophthalmol; Vol 104, pp. 104-111. 1997 Jan 01. Sadun FFeldon SEWeiss MHKrieger MD Septic cavernous sinus thrombosis following transsphenoidal craniotomy. Case report.; Journal of neurosurgery; Vol 85(5). 1996 Nov.