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Flaum Eye Institute / Research / Labs / Wozniak Lab / Projects / Tools for compound screening and prioritization

 

Tools for compound screening and prioritization

DNAIn order to further advance lead compounds we are developing genetic tool systems to interrogate the potential mechanism of action(s) of novel antimicrobial drug compounds in S. aureus.  Through leveraging CRISPR technology we are defining a novel strain set which will allow for the identification of putative cellular targets of drug hits identified in our antimicrobial drug screening campaigns.

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