Contact Us

Department of Biochemistry & Biophysics

University of Rochester Medical Center

work MC 3-8529

601 Elmwood Ave

Box 712

Rochester, NY 14642

p 585-275-1446

f 585-275-6007

Research

Cell Cycle & Cancer
Understanding the differences in cell division and its relationship to the development of cancer.
Active Research Laboratories
- Bambara Lab Human Genome Stability, DNA Damage Response, HIV Replication & Evolution
- Hilf Lab Hormone Action in Mammory Cancer
- Land Lab Cooperation of Oncogenic Mutations in the Control of Malignancy
- Maines Lab Heme Oxygenase, Biliverdin Reductase & Cell Signalling
- Munger Lab Mechanisms of Pathogenic Metabolic Manipulation
Cell Signaling & Metabolic Regulation
Understanding complex system of communication that governs basic cellular activities and coordinates cell actions in order to effectively treat diseases.
Active Research Laboratories
- Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
- Gunter Lab Membrane Transport, Bioenergetics, Calcium Regulation
- Land Lab Cooperation of Oncogenic Mutations in the Control of Malignancy
- Munger Lab Mechanisms of Pathogenic Metabolic Manipulation
Chromatin Structure, Gene Regulation & Repair
Study of defined protein-DNA interactions, protein modification and mutations that influence chromatin structure and gene regulation.
Active Research Laboratories
- Bambara Lab Human Genome Stability, DNA Damage Response, HIV Replication & Evolution
- Bernhard Lab Physics & Chemistry of DNA Damage Produced by Ionizing Radiation
- Grayhack Lab The Roles of the Genetic Code in Translation
- Hayes Lab Chromatin Structure
- Hilf Lab Hormone Action in Mammory Cancer
- Lawrence Lab DNA-Damage Induced Mutagenesis
- Sherman Lab Yeast Molecular Biology & Genetics
Genomics & Model Systems for Development
Determining DNA sequences of organisms and fine-scale genetic mapping efforts.
Active Research Laboratories
- Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
- Grayhack Lab The Roles of the Genetic Code in Translation
- Phizicky Lab tRNA Biogenesis, Function & Quality Control
- Puzas Lab Molecular and Cellular Biology of the Skeletal System
- Rosier Lab Regulation of Endochondral Ossification
Membrane Biology
The study of the biological and physiochemical characteristics of membranes.
Active Research Laboratories
- Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
- Grossfield Lab Use of Computer Modeling to Understand the Structure and Thermodynamics of Biological Molecules
- Gunter Lab Membrane Transport, Bioenergetics, Calcium Regulation
- Mathews Lab Computational Biology and Bioinformatics
- Waugh Lab Cell Deformability & Cell Adhesion
Molecular Biophysics
Combines concepts in physics, chemistry, engineering, mathematics and biology.
Active Research Laboratories
- Bernhard Lab Physics & Chemistry of DNA Damage Produced by Ionizing Radiation
- Ermolenko Lab Mechanism of Protein Synthesis
- Grossfield Lab Use of Computer Modeling to Understand the Structure and Thermodynamics of Biological Molecules
- Gunter Lab Membrane Transport, Bioenergetics, Calcium Regulation
- Kielkopf Lab Study of pre-RNA Transcripts in Order to Treat Human Genetic Diseases
- Miller (Benjamin) Lab Molecular Recognition & Biosensing
- Wedekind Lab Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
Protein Structure & Function
Structure and function of proteins from primary to quaternary structures.
Active Research Laboratories
- Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
- Fay Lab Human Factor VIII Structure & Function
- Gunter Lab Membrane Transport, Bioenergetics, Calcium Regulation
- Hayes Lab Chromatin Structure
- Kielkopf Lab Study of pre-RNA Transcripts in Order to Treat Human Genetic Diseases
- Maines Lab Heme Oxygenase, Biliverdin Reductase & Cell Signalling
- Maquat Lab Normal & Disease-Associated RNA Decay
- Miller (Benjamin) Lab Molecular Recognition & Biosensing
- Phizicky Lab tRNA Biogenesis, Function & Quality Control
- Smith Lab Regulating Gene Expression at the Level of Messenger RNA Expression and Processing
- Wedekind Lab Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
- Yu Lab Functions & Mechanisms of RNA Modifications
RNA Structure & Processing
Generation of a mature mRNA (for protein genes) or a functional tRNA or rRNA from the primary transcript.
Active Research Laboratories
- Butler Lab Regulation of mRNA Expression in the Nucleus of Eukaryotic Cells
- Ermolenko Lab Mechanism of Protein Synthesis
- Kielkopf Lab Study of pre-RNA Transcripts in Order to Treat Human Genetic Diseases
- Maquat Lab Normal & Disease-Associated RNA Decay
- Mathews Lab Computational Biology and Bioinformatics
- Phizicky Lab tRNA Biogenesis, Function & Quality Control
- Platt Lab Molecular Mechanisms of Gene Expression
- Sherman Lab Yeast Molecular Biology & Genetics
- Smith Lab Regulating Gene Expression at the Level of Messenger RNA Expression and Processing
- Wedekind Lab Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
- Yu Lab Functions & Mechanisms of RNA Modifications