Ollivier Hyrien, PhD

Associate Professor of Biostatistics and Computational Biology
Ph.D. (2001) University of Rennes I, France


 

Contact Information:

University of Rochester
Dept of Biostatistics and Computational Biology
601 Elmwood Avenue Box 630
Rochester, New York 14642
 
Office: Saunders Research Building 4219
Phone: (585) 275-5303
Fax: (585) 273-1031
E-mail: Ollivier_Hyrien@urmc.rochester.edu
Ollivier Hyrien, PhD

Selected References

  • Chen. R. and Hyrien, O. (2014). On classes of equivalence and identifiability for age-dependent branching processes. Advances in Applied Probability, to appear.
  • Hyrien O. and Yanev N.M. (2012). Asymptotic behavior of cell populations described by two-type reducible age-dependent branching processes with non-homogeneous immigration. Mathematical Population Studies, 19, 164-176.
  • Chen R. and Hyrien O. (2011). Quasi- and pseudo-likelihood estimation for discretely observed Markov branching processes. Journal of Statistical Planning and Inference, 141, 2209-2227.
  • Chen R., Hyrien O., Mayer-Proschel M., and Noble M. (2011). A composite likelihood approach to the analysis of longitudinal clonal data under an age-dependent branching process. Biostatistics, 12, 173:191.
  • Hyrien O., Chen R., Mayer-Proschel M., and Noble M. (2010). Saddlepoint approximations to the moments of age-dependent branching processes, with applications. Biometrics, 66:567-577.
  • Hyrien O., Dietrich J., and Noble M. (2010). Mathematical and experimental approaches to identify and predict the effects of chemotherapy on neuroglial precursors. Cancer Research, 70, 10051-10059.
  • Hyrien O., Chen R., and Zand M.S. (2010). An age-dependent branching process model for the analysis of CFSE-labeling experiments. Biology Direct (Mathematical Biology section), 5:41.
  • Hocde S.A., Hyrien O., Waugh R.E. (2009). Molecular accessibility in relation to cell surface topography and compression against a flat substrate. Biophysical Journal, 97, 369-378.
  • Hocde S.A., Hyrien O., Waugh R.E. (2009). Cell adhesion molecule distribution relative to Neutrophil Surface Topography assessed by TIRFM. Biophysical Journal, 97, 379-387.
  • Hyrien O. and Zand M.S. (2008). A mixture model with dependent observations for the analysis of CFSE-labeling experiments. Journal of the American Statistical Association, 103, 222-239.
  • Hyrien O. (2007) A pseudo-maximum likelihood estimator for discretely observed multitype Bellman-Harris branching processes. Journal of Statistical Planning and Inference, 137, 1375-1388.
  • Hyrien O., Ambeskovic I., Mayer-Proschel M., Noble M., and Yakovlev A. (2006). Stochastic modeling of oligodendrocyte generation in cell culture: model validation with time-lapse data. Theoretical Biology and Medical Modelling 3:21.
  • Hanin L., Hyrien O., Bedford J., and Yakovlev A. (2006). A comprehensive stochastic model of irradiated cell population in cell culture. Journal of Theoretical Biology, 239, 401-416.
  • Hyrien O., Mayer-Proschel M., Noble and M., Yakovlev A. (2005). A stochastic model to analyze clonal data on multi-type cell populations. Biometrics, 61, 199-207.
  • Hyrien O., Mayer-Proschel M., Noble M., and Yakovlev A. (2005). Estimating the life-span of oligodendrocytes from clonal data on their development in cell culture. Mathematical Biosciences, 193, 255-274.