Skip to main content
Explore URMC

Juilee Thakar, Ph.D.

Contact Information

Phone Numbers

Office: (585) 276-6925

Research Labs

Faculty Appointments



Thakar lab uses systems biology approaches to identify immune signatures that can predict outcome of an immune response to infections or vaccinations. We develop computational tools to model probable trajectories of the immune response which then allows us to identify parameters that can predict future outcomes of the disease. This has direct implications in early diagnosis. The models also reveal the mechanisms of pathogenesis. This work is based on multi-parameter datasets including gene expression, serum cytokine levels and known information about signaling and metabolic pathways.



BSc | India-Univ of Pune, Pune
Microbiology and Mathematics

MSc with certificate | India-Univ of Pune, Pune
Microbiology and Computational Biology

PhD | Germany-U Wurzburg

Post-doctoral Training & Residency

01/01/2011 - 10/31/2013
Associate Research Scientist, Department of Pathology, Yale School of Medicine, USA

05/01/2006 - 12/31/2010
Cancer Research Institute fellow, Department of Physics, Pennsylvania State University, USA


2016 - 2017
Novel Biostatistical and Epidemiologic Methods (NBEM) Awards
Sponsor: Clinical & Translational Science Institute
Location: University of Rochester Medical School

2015 - 2016
PhRMA research starter award in informatics
Sponsor: Pharmaceutical Research and Manufacturers of America

Beutner Speaker
Location: Buffalo Immunology Conference

2008 - 2010
Cancer-Research-Institute fellowship
Sponsor: Cancer Research Institute fellowship

Shankar Subramaniam award in systems biology research
Location: Pennsylvania State University

The Association for the Study of Animal Behavior fellowship
Location: Edinburgh, UK and Pune, India

VIEW ALL expand_more


Journal Articles

Huang Y, Zhang Y, Seaton KE, De Rosa S, Heptinstall J, Carpp LN, Randhawa AK, McKinnon LR, McLaren P, Viegas E, Gray GE, Churchyard G, Buchbinder SP, Edupuganti S, Bekker LG, Keefer MC, Hosseinipour MC, Goepfert PA, Cohen KW, Williamson BD, McElrath MJ, Tomaras GD, Thakar J, Kobie JJ, . "Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens." EBioMedicine.. 2022 Sep 27; 84:104271. Epub 2022 Sep 27.

Zhou T, Gilliam NJ, Li S, Spaudau S, Osborn RM, Anderson CS, Mariani TJ, Thakar J, Dewhurst S, Mathews DH, Huang L, Sun Y. "Generation and functional analysis of defective viral genomes during SARS-CoV-2 infection." bioRxiv : the preprint server for biology.. 2022 Sep 23; Epub 2022 Sep 23.

Palshikar MG, Palli R, Tyrell A, Maggirwar S, Schifitto G, Singh MV, Thakar J. "Executable models of immune signaling pathways in HIV-associated atherosclerosis." NPJ systems biology and applications.. 2022 Sep 21; 8(1):35. Epub 2022 Sep 21.

Books & Chapters

Book Title: Occupational Health and the Service Member
Author List: Timothy M. Mallon*, Richard Phipps, Juilee Thakar, Collynn Woeller, Dean P. Jones, Douglas I. Walker, Karan Uppal, Mark Utell and Thomas Thatcher
Edited By: Timothy M. Mallon
Published By: Office of The Surgeon General Borden Institute US Army Medical Department Center 2019

Chapter Title: Developing Network Models of Multiscale Host Responses Involved in Infections and Diseases.
Book Title: Computational Cell Biology
Author List: Rohith Palli and Juilee Thakar
Edited By: Louise von Stechow and Alberto Santos Delgado
Published By: Springer Science and Humana Press 2018 in New York

Chapter Title: Mathematical Models as Tools to Enable Infectious Diseases Research
Book Title: Emerging Trends in Antibacterial Discovery
Author List: Juilee Thakar and Eric Harvill
Edited By: Alita A. Miller and Paul F. Miller
Published By: Caister Academic Press 2011