Welcome to the Thakar Lab
Immune response to infections and vaccination depends on several factors including age, immunogenicity of the antigens, host genotype and host’s immune history.
The research focus of our lab is to delineate the effects of these factors using bioinformatics, systems biology and dynamic modeling tools. We typically integrate different datasets including gene expression, serum cytokine levels and known information about signaling and metabolic pathways.
Current Research Projects
- PathCellNet: Cell-type specific pathogen-response network explorer.J Immunol Methods. 439, 15-22. (2016 Dec 01).
- MicroRNAs as Novel Biomarkers of Deployment Status and Exposure to Polychlorinated Dibenzo-p-Dioxins/Dibenzofurans.J Occup Environ Med. 58, S89-96. (2016 Aug 01).
- Detection of Serum microRNAs From Department of Defense Serum Repository: Correlation With Cotinine, Cytokine, and Polycyclic Aromatic Hydrocarbon Levels.J Occup Environ Med. 58, S62-71. (2016 Aug 01).