Principal Investigator

Mark Raymond Buckley, Ph.D. University of Rochester work Box 270168 Rochester NY 14627-0168 office: Goergen Hall 317 p (585) 276-4195

Contact

Buckley Lab University of Rochester work Goergen Hall 321 Rochester NY 14627-0168

Affiliations

Viscoelasticity in Connective Tissues

Confocal micrograph of articular cartilage under dynamic shear loading. The black stripes are photobleached lines used as markers to track time-dependent tissue deformation.

Mechanics plays a key role in the onset, progression and treatment of several diseases that affect cartilage, tendon, cornea, sclera and other connective tissues. The Buckley lab is interested in evaluating pathology-associated mechanical changes in these tissues and using our findings to develop novel diagnostic tools and therapeutic strategies. We characterize the viscoelastic (i.e., rate- and time-dependent) mechanical response of connective tissues in vivo and in viable explants across multiple length scales using image-guided mechanical testing methods. Our current focus is on diseases of the musculoskeletal system (e.g., osteoarthritis and tendinopathy) and diseases of the eye (e.g., keratoconus and glaucoma) with significant public health impacts.


Current Research Projects