The protein-DNA assemblies that comprise chromatin serve to compact and store eukaryotic DNA in a systematic and orderly manner, and are involved in the regulation of nuclear processes such as transcription. Currently, research in the lab covers four areas related to chromatin structure and function.
Dr. Hayes is also the Principal Investigator of the William A. Bernhard Memorial Lab. Please visit the lab site to learn more about the physics & chemistry of DNA damage produced by ionizing radiation.
- A brief review of nucleosome structure.FEBS Lett. (2015 May 14).
- A distinct switch in interactions of the histone H4 tail domain upon salt-dependent folding of nucleosome arrays.J Biol Chem. 289, 27342-51. (2014 Sep 26).
- Intra- and inter-nucleosome interactions of the core histone tail domains in higher-order chromatin structure.Chromosoma. 123, 3-13. (2014 Mar 01).