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2017 Published Articles

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Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis. Domingo-Gonzalez R, Das S, Griffiths KL, Ahmed M, Bambouskova M, Gopal R, Gondi S, Muñoz-Torrico M, Salazar-Lezama MA, Cruz-Lagunas A, Jiménez-Álvarez L, Ramirez-Martinez G, Espinosa-Soto R, Sultana T, Lyons-Weiler J, Reinhart TA, Arcos J, de la Luz Garcia-Hernandez M, Mastrangelo MA, Al-Hammadi N, Townsend R, Balada-Llasat JM, Torrelles JB, Kaplan G, Horne W, Kolls JK, Artyomov MN, Rangel-Moreno J, Zúñiga J, Khader SA. JCI insight. 2017 Oct 5; 2(19). Epub 2017 Oct 05.

Bone Marrow-Derived Mesenchymal Stem Cells From Patients With Systemic Lupus Erythematosus Have a Senescence-Associated Secretory Phenotype Mediated by a Mitochondrial Antiviral Signaling Protein-Interferon-β Feedback Loop. Gao L, Bird AK, Meednu N, Dauenhauer K, Liesveld J, Anolik J, Looney RJ. Arthritis Rheumatol. 2017 Aug;69(8):1623-1635. Epub 2017 Jul 11.

Hospitalization of patients with systemic lupus erythematosus is a major cause of direct and indirect healthcare costs. Anandarajah AP, Luc M, Ritchlin CT. Lupus. 2017; 26(7):756.

The Relationship between Focal and Generalized Bone Loss in Rheumatoid Arthritis. Anandarajah AP, El-Taha M; Peng C, Ritchlin, CT. Curr Rheumatol Rev. 2017;13(2):152-157.

Neutrophils Slow Disease Progression in Murine Lupus via Modulation of Autoreactive Germinal Centers. Bird AK, Chang M, Barnard J, Goldman BI, Meednu N, Rangel-Moreno J, Anolik JH. J Immunol. 2017 July 15;199(2)458-466. Epub 2017 Jun 5.

Novel role for IL-22 in protection during chronic Mycobacterium tuberculosis HN878 infection. Treerat P, Prince O, Cruz-Lagunas A, Muñoz-Torrico M, Salazar-Lezama MA, Selman M, Fallert-Junecko B, Reinhardt TA, Alcorn JF, Kaushal D, Zuñiga J, Rangel-Moreno J, Kolls JK, Khader SA. Mucosal Immunol. 2017 Jul;10(4):1069-1081. Epub 2017 Mar 1.

Rationalized design of a mucosal vaccine protects against Mycobacterium tuberculosis challenge in mice. Ahmed M, Jiao H, Domingo-Gonzalez R, Das S, Griffiths KL, Rangel-Moreno J, Nagarajan UM, Khader SA. J Leukoc Biol. 2017 Jun;101(6):1373-1381. Epub 2017 Mar 3.

PKK deficiency in B cells prevents lupus development in SLE lupus mice. Oleksyn D, Zhao J, Vosoughi A, Zhao JC, Misra R, Pentland AP, Ryan D, Anolik J, Ritchlin C, Looney J, Anandarajah AP, Schwartz G, Calvi LM, Georger M, Mohan C, Sanz I, Chen L. Immunol Lett. 2017 May;185:1-11.

Psoriatic Arthritis. Ritchlin, CT, Colbert, RA, Gladman, DD. N Engl J Med. 2017 Mar 9;376(10):957-970.

Ixekizumab, an interleukin-17A specific monoclonal antibody, for the treatment of biologic-naive patients with active psoriatic arthritis: results from the 24-week randomised, double-blind, placebo-controlled and active (adalimumab)-controlled period of the phase III trial SPIRIT-P1. Mease PJ, van der Heijde D, Ritchlin CT, Okada M, Cuchacovich RS, Shuler CL, Lin CY, Braun DK, Lee CH, Gladman DD. Ann Rheum Dis. 2017 Jan;76(1):79-87.

HLA Alleles are Genetic Markers for Susceptibility and Resistance towards Leprosy in a Mexican Mestizo Population. Aguilar-Medina M, Escamilla-Tilch M, Frías-Castro LO, Romero-Quintana G, Estrada-García I, Estrada-Parra S, Granados J, Arambula Meraz E, Sánchez-Schmitz G, Khader SA, Rangel-Moreno J, Ramos-Payán R. Ann Hum Genet. 2017 Jan;81(1):35-40. Epub 2016 Dec 27.