Institute Of Immunology
Russian Ministry of Health
Allergy, Immunology and Rheumatology
Dr. Kuzin is currently working on two major research projects. The goal of the first one is to elucidate the mechanisms that regulate expression and recombination of immunoglobulin heavy chain (IgH) genes. Specifically, he is interested in the role of enhancer specificity in the IgH locus regulation. continued
Kuzin, I.I., Ugine, G.D., Barth, R.K., Shultz, L.D., Nahm, M.H., Young, F.M., Bottaro, A. "A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens." Eur J Immunol. 2004 Jul;34(7):1807-16. View article in PubMed.
Filatov, A.V., Shmigol, I.B., Kuzin, I.I., Sharonov, G.V., Feofanov, A.V. "Resistance of cellular membrane antigens to solubilization with Triton X-100 as a marker of their association with lipid rafts-analysis by flow cytometry." J Immunol Methods. 2003 Jul;278(1-2):211-9. View article in PubMed.
Kuzin, I.I., Ugine, G.D., Wu, D., Young, F., Chen, J., Bottaro, A. "Normal isotype switching in B cells lacking the I mu exon splice donor site: evidence for multiple I mu-like germline transcripts." J Immunol 2000 Feb 1;164(3);1451-7. View article in PubMed.
Igor Kuzin, M.D., Ph.D.
University of Rochester
601 Elmwood Ave., Box 695
Rochester, NY 14642