Bottaro Lab

Andrea Bottaro, Ph.D.

Ph.D. 1987
Italy Non-Medical School

Associate Professor of Medicine
Division of Allergy/Immunology and Rheumatology

Research Overview

Dr. Bottaro's research interests include B cell activation, the molecular biology of antibody gene expression and reconbination, immunoglobulin class switching and trangenic/knock-out mouse models.

Recent Publications

 

 

Igor Kuzin, M.D., Ph.D.

Ph.D. 1984 Institute Of Immunology, Russian Ministry of Health


Senior Instructor

Division of Allergy/Immunology and Rheumatology

Contact Information:

Igor Kuzin, M.D., Ph.D.
University of Rochester
601 Elmwood Ave., Box 695
Rochester, NY 14642
Office: 585-275-2180
Igor_Kuzin@urmc.
rochester.edu

Research Overview

     Dr. Kuzin is currently working on two major research projects. The goal of the first one is to elucidate the mechanisms that regulate expression and recombination of immunoglobulin heavy chain (IgH) genes. Specifically, he is interested in the role of enhancer specificity in the IgH locus regulation. continued

Recent Publications

   Kuzin, I.I., Ugine, G.D., Barth, R.K., Shultz, L.D., Nahm, M.H., Young, F.M., Bottaro, A. "A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens." Eur J Immunol. 2004 Jul;34(7):1807-16.  View article in PubMed.           
   Filatov, A.V., Shmigol, I.B., Kuzin, I.I., Sharonov, G.V., Feofanov, A.V. "Resistance of cellular membrane antigens to solubilization with Triton X-100 as a marker of their association with lipid rafts-analysis by flow cytometry." J Immunol Methods. 2003 Jul;278(1-2):211-9. View article in PubMed.    
   Kuzin, I.I., Ugine, G.D., Wu, D., Young, F., Chen, J., Bottaro, A. "Normal isotype switching in B cells lacking the I mu exon splice donor site: evidence for multiple I mu-like germline transcripts." J Immunol 2000 Feb 1;164(3);1451-7. View article in PubMed.

                                                         The Bottaro Lab

                group lab photo

Contact

Andrea Bottaro, Ph.D.
University of Rochester
601 Elmwood Ave., Box 695
Rochester, NY 14642
Office: 585-275-2171
Andrea_Bottaro@urmc.
rochester.edu

 

Lab Members

Safeihkhatoon Moshkani

Graduate Student