Trial Innovation Network Proposal Consultation
The UR CTSI supports researchers who conduct multi-site clinical trials by helping them collaborate with the Trial Innovation Network (TIN). Our team can connect lead investigators of multi-site clinical trials with the TIN, which will give you access to experienced clinical trialists and experts in participant recruitment and retention from across the Clinical and Translational Science Awards (CTSA) Program.
Features
The TIN offers a variety of resources:
- Study planning (design, budget, timelines, feasibility)
- Single IRB support
- Standard agreements
- Recruitment and retention planning
- Recruitment feasibility assessment
- Recruitment materials
- Community engagement studios
- EHR-based cohort assessment
- Innovations in clinical effectiveness trial design
- Expression of Interest (EOI) - recruit sites for your study by connecting with over 60 CTSA Program hubs using a single request. The process takes only three weeks to complete and provides you with an aggregated response report. The request includes the following free services:
- Feasibility assessment and review of study budget and protocol by the interested site PI
- Site PI identification
- EHR-based cohort assessment of the site
- Study implementation service for multi-site clinical trial
- TIN may support the implementation of a trial by acting as the single IRB, data coordinating center, and/or clinical coordinating center. Support will be based on the needs of the trial and the responsibilities taken on by the TIN will be discussed and agreed upon during a comprehensive consultation.
- All costs related to those activities will be written into the grant budget before it is sent to the funder.
Get Started
Full-time faculty with a study in the development phase (not yet funded) may request a free clinical trial consultation tailored to their specific needs. Faculty will first meet with the UR CTSI TIN liaison team and obtain approval from one of the UR CTSI directors.
- Proposals will be evaluated by the network for feasibility, potential for operational innovation, resource requirements, and ability of the TIN to deliver services or consultations.
- Approved proposals will be assigned to a Trial Innovation Center (Duke University, University of Utah, or Johns Hopkins University) or the Recruitment Innovation Center (Vanderbilt University) and services or consultations will be provided after decisions are made.
- Looking for more answers? Check out TIN’s proposal process.
Standard Due Dates
Please refer to the grant application cycles by NIH and check your target grant due date as early as possible. If you submit your proposal to the UR CTSI’s TIN liaison team approximately 3-6 months prior to the grant submission deadline, you would have more options for TIN support.
Confidentiality
All proposals submitted to the TIN are kept confidential and only disclosed to the extent necessary to provide consultation or services. University of Rochester School of Medicine and Dentistry executed the TIN Umbrella Confidential Disclosure Agreement (CDA) which is effective until July 31, 2028.
Resources
The TIN gives investigators and multisite trial teams from around the CTSA Program the chance to share their expertise and learn from one another through a variety of webinars and meetings. Teams can also share clinical trial related tools and resources in the TIN Toolbox. You can also peruse a list of publications related to TIN trials and search by topics, like "recruitment and retention" or "COVID."
TIN Webinar
Attend: All University of Rochester faculty, staff, and trainees are welcome to attend TIN webinars to learn about clinical trial best practices and lessons learned from experts around the country. You can find information about upcoming TIN webinars on the TIN Resources & Events page, UR CTSI News & Events page, and in the UR CTSI Weekly Update (subscribe). Recordings of past TIN webinars can be found on the Clinical Research Webinar archive.
Host: University of Rochester faculty, staff, and trainees can also host a Collaboration Webinar to share their expertise, methods, and/or best practices to improve the way trials are conducted. Contact the UR CTSI Research Help Desk to host a TIN webinar.
TIN Toolbox
Access resources and tools developed by TIN experts in the TIN Toolbox. Note: These materials are not meant for the general public. Some materials may not be suitable for adoption in isolation of a comprehensive engagement, recruitment, and retention plan.
If you would like to share your resource with the TIN Toolbox, please contact the UR CTSI Research Help Desk.
TIN Publications
Review selected publications from the TIN. You can also search findings by: IRB, Studies Supported, Study Conduct, COVID, Recruitment and Retention, and TIN.
Need help? Email us at ResearchHelp@urmc.rochester.edu.
Past Projects
URMC concussion researcher Jeffery Bazarian, MD, MPH, credits the UR CTSI and the Trial Innovation Network with helping him connect with researchers across the country to be a part of a $10 million grant to study prolonged concussion symptoms in 11- to 18-year-olds. Read More.
FAQs
Still have questions? Check out the frequently asked questions on the TIN website.