Flaum Eye Institute / Research / Labs / Merigan Lab / Publications

Recent Publications

1. Cai Y
2. Druszkiewicz E
3. Patterson SS
4. Parkins K
5. Mcgregor JE
6. Merigan WH
7. Fienup JR
8. Williams DR
Phase diversity improves retinal image quality in adaptive optics scanning light ophthalmoscopy.; bioRxiv : the preprint server for biology. 2025 Dec 18.
1. Patterson SS
2. Cai Y
3. Yang Q
4. Merigan WH
5. Williams DR
Asymmetric activation of retinal ON and OFF pathways by AOSLO raster-scanned visual stimuli.; Biomedical optics express; Vol 16(7), pp. 2663-2691. 2025 Jun 09.
1. Patterson SS
2. Cai Y
3. Yang Q
4. Merigan WH
5. Williams DR
Asymmetric Activation of Retinal ON and OFF Pathways by AOSLO Raster-Scanned Visual Stimuli.; bioRxiv : the preprint server for biology. 2024 Dec 17.
1. Godat T
2. Kohout K
3. Parkins K
4. Yang Q
5. McGregor JE
6. Merigan WH
7. Williams DR
8. Patterson SS
Cone-Opponent Ganglion Cells in the Primate Fovea Tuned to Non-Cardinal Color Directions.; The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024 Mar 28.
1. Godat T
2. Kohout K
3. Yang Q
4. Parkins K
5. McGregor JE
6. Merigan WH
7. Williams DR
8. Patterson SS
Cone-Opponent Ganglion Cells in the Primate Fovea Tuned to Non-Cardinal Color Directions.; bioRxiv : the preprint server for biology. 2023 Sep 16.
1. Godat T
2. Cottaris NP
3. Patterson S
4. Kohout K
5. Parkins K
6. Yang Q
7. Strazzeri JM
8. McGregor JE
9. Brainard DH
10. Merigan WH
11. Williams DR
Contributed Session III: In vivo calcium imaging of macaque foveolar retinal ganglion cells reveals spatiochromatic receptive field properties.; Journal of vision; Vol 23(11), pp. 32. 2023 Sep 01.
1. Godat T
2. Cottaris NP
3. Patterson S
4. Kohout K
5. Parkins K
6. Yang Q
7. Strazzeri JM
8. McGregor JE
9. Brainard DH
10. Merigan WH
11. Williams DR
In vivo chromatic and spatial tuning of foveolar retinal ganglion cells in Macaca fascicularis.; PloS one; Vol 17(11), pp. e0278261. 2022 Jan 29.
1. McGregor JE
2. Kunala K
3. Xu Z
4. Murphy PJ
5. Godat T
6. Strazzeri JM
7. Bateman BA
8. Fischer WS
9. Parkins K
10. Chu CJ
11. Puthussery T
12. Williams DR
13. Merigan WH
Optogenetic therapy restores retinal activity in primate for at least a year following photoreceptor ablation.; Molecular therapy : the journal of the American Society of Gene Therapy. 2021 Sep 18.
1. Aboualizadeh E
2. Phillips MJ
3. McGregor JE
4. DiLoreto DA
5. Strazzeri JM
6. Dhakal KR
7. Bateman B
8. Jager LD
9. Nilles KL
10. Stuedemann SA
11. Ludwig AL
12. Hunter JJ
13. Merigan WH
14. Gamm DM
15. Williams DR
Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution.; Stem cell reports. 2020 Jul 21.
1. Dhakal KR
2. Walters S
3. McGregor JE
4. Schwarz C
5. Strazzeri JM
6. Aboualizadeh E
7. Bateman B
8. Huxlin KR
9. Hunter JJ
10. Williams DR
11. Merigan WH
Localized Photoreceptor Ablation Using Femtosecond Pulses Focused With Adaptive Optics.; Translational vision science & technology; Vol 9(7). 2020 Jun.
1. Byrne LC
2. Day TP
3. Visel M
4. Strazzeri JA
5. Fortuny C
6. Dalkara D
7. Merigan WH
8. Schaffer DV
9. Flannery JG
In vivo-directed evolution of adeno-associated virus in the primate retina.; JCI insight; Vol 5(10). 2020 May 21.
1. McGregor JE
2. Godat T
3. Dhakal KR
4. Parkins K
5. Strazzeri JM
6. Bateman BA
7. Fischer WS
8. Williams DR
9. Merigan WH
Optogenetic restoration of retinal ganglion cell activity in the living primate.; Nature communications; Vol 11(1). 2020 Apr 03.
1. Hunter JJ
2. Merigan WH
3. Schallek JB
Imaging Retinal Activity in the Living Eye.; Annual review of vision science; Vol 5. 2019 Sep 15.
1. McGregor JE
2. Williams DR
3. Merigan WH
Functional Assessment of Vision Restoration.; Advances in experimental medicine and biology; Vol 1185. 2019.
1. Walters S
2. Schwarz C
3. Sharma R
4. Rossi EA
5. Fischer WS
6. DiLoreto DA
7. Strazzeri J
8. Nelidova D
9. Roska B
10. Hunter JJ
11. Williams DR
12. Merigan WH
Cellular-scale evaluation of induced photoreceptor degeneration in the living primate eye.; Biomedical optics express; Vol 10(1). 2019 Jan 01.
1. Cheong SK
2. Strazzeri JM
3. Williams DR
4. Merigan WH
All-optical recording and stimulation of retinal neurons in vivo in retinal degeneration mice.; PloS one; Vol 13(3). 2018.
1. Cheong SK
2. Xiong W
3. Strazzeri JM
4. Cepko CL
5. Williams DR
6. Merigan WH
In Vivo Functional Imaging of Retinal Neurons Using Red and Green Fluorescent Calcium Indicators.; Advances in experimental medicine and biology; Vol 1074. 2018.
1. McGregor JE
2. Yin L
3. Yang Q
4. Godat T
5. Huynh KT
6. Zhang J
7. Williams DR
8. Merigan WH
Functional architecture of the foveola revealed in the living primate.; PloS one; Vol 13(11). 2018.
1. Marcos S
2. Werner JS
3. Burns SA
4. Merigan WH
5. Artal P
6. Atchison DA
7. Hampson KM
8. Legras R
9. Lundstrom L
10. Yoon G
11. Carroll J
12. Choi SS
13. Doble N
14. Dubis AM
15. Dubra A
16. Elsner A
17. Jonnal R
18. Miller DT
19. Paques M
20. Smithson HE
21. Young LK
22. Zhang Y
23. Campbell M
24. Hunter J
25. Metha A
26. Palczewska G
27. Schallek J
28. Sincich LC
Vision science and adaptive optics, the state of the field.; Vision research; Vol 132. 2017 Mar.
1. Kotterman MA
2. Yin L
3. Strazzeri JM
4. Flannery JG
5. Merigan WH
6. Schaffer DV
Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates.; Gene therapy; Vol 22(2). 2015 Feb.
1. Yang Q
2. Yin L
3. Nozato K
4. Zhang J
5. Saito K
6. Merigan WH
7. Williams DR
8. Rossi EA
Calibration-free sinusoidal rectification and uniform retinal irradiance in scanning light ophthalmoscopy.; Optics letters; Vol 40(1). 2015 Jan 1.
1. Yin L
2. Masella B
3. Dalkara D
4. Zhang J
5. Flannery JG
6. Schaffer DV
7. Williams DR
8. Merigan WH
Imaging light responses of foveal ganglion cells in the living macaque eye.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 34(19). 2014 May 7.
1. Strazzeri JM
2. Hunter JJ
3. Masella BD
4. Yin L
5. Fischer WS
6. DiLoreto DA
7. Libby RT
8. Williams DR
9. Merigan WH
Focal damage to macaque photoreceptors produces persistent visual loss.; Experimental eye research; Vol 119. 2014 Feb.
1. Dalkara D
2. Byrne LC
3. Klimczak RR
4. Visel M
5. Yin L
6. Merigan WH
7. Flannery JG
8. Schaffer DV
In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous.; Science translational medicine; Vol 5(189). 2013 Jun 12.
1. Yin L
2. Geng Y
3. Osakada F
4. Sharma R
5. Cetin AH
6. Callaway EM
7. Williams DR
8. Merigan WH
Imaging light responses of retinal ganglion cells in the living mouse eye.; Journal of neurophysiology; Vol 109(9). 2013 May.
1. Sharma R
2. Yin L
3. Geng Y
4. Merigan WH
5. Palczewska G
6. Palczewski K
7. Williams DR
8. Hunter JJ
In vivo two-photon imaging of the mouse retina.; Biomedical optics express; Vol 4(8). 2013.
1. Geng Y
2. Dubra A
3. Yin L
4. Merigan WH
5. Sharma R
6. Libby RT
7. Williams DR
Adaptive optics retinal imaging in the living mouse eye.; Biomedical optics express; Vol 3(4). 2012 Apr 1.
1. Hunter JJ
2. Morgan JI
3. Merigan WH
4. Sliney DH
5. Sparrow JR
6. Williams DR
The susceptibility of the retina to photochemical damage from visible light.; Progress in retinal and eye research; Vol 31(1). 2012 Jan.
1. Yin L
2. Greenberg K
3. Hunter JJ
4. Dalkara D
5. Kolstad KD
6. Masella BD
7. Wolfe R
8. Visel M
9. Stone D
10. Libby RT
11. Diloreto D
12. Schaffer D
13. Flannery J
14. Williams DR
15. Merigan WH
Intravitreal injection of AAV2 transduces macaque inner retina.; Investigative ophthalmology & visual science; Vol 52(5). 2011 Apr.
1. Rossi EA
2. Chung M
3. Dubra A
4. Hunter JJ
5. Merigan WH
6. Williams DR
Imaging retinal mosaics in the living eye.; Eye (London, England); Vol 25(3). 2011 Mar.
1. Hunter JJ
2. Masella B
3. Dubra A
4. Sharma R
5. Yin L
6. Merigan WH
7. Palczewska G
8. Palczewski K
9. Williams DR
Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy.; Biomedical optics express; Vol 2(1). 2010.
1. Morgan JI
2. Hunter JJ
3. Merigan WH
4. Williams DR
The reduction of retinal autofluorescence caused by light exposure.; Investigative ophthalmology & visual science; Vol 50(12). 2009 Dec.
1. Scoles D
2. Gray DC
3. Hunter JJ
4. Wolfe R
5. Gee BP
6. Geng Y
7. Masella BD
8. Libby RT
9. Russell S
10. Williams DR
11. Merigan WH
In-vivo imaging of retinal nerve fiber layer vasculature: imaging histology comparison.; BMC ophthalmology; Vol 9. 2009 Aug 23.
1. Morgan JI
2. Dubra A
3. Wolfe R
4. Merigan WH
5. Williams DR
In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic.; Investigative ophthalmology & visual science; Vol 50(3). 2009 Mar.
1. Morgan JI
2. Hunter JJ
3. Masella B
4. Wolfe R
5. Gray DC
6. Merigan WH
7. Delori FC
8. Williams DR
Light-induced retinal changes observed with high-resolution autofluorescence imaging of the retinal pigment epithelium.; Investigative ophthalmology & visual science; Vol 49(8). 2008 Aug.
1. Gray DC
2. Wolfe R
3. Gee BP
4. Scoles D
5. Geng Y
6. Masella BD
7. Dubra A
8. Luque S
9. Williams DR
10. Merigan WH
In vivo imaging of the fine structure of rhodamine-labeled macaque retinal ganglion cells.; Investigative ophthalmology & visual science; Vol 49(1). 2008 Jan.
1. Hayes RD
2. Merigan WH
Mechanisms of Sensitivity Loss due to Visual Cortex Lesions in Humans and Macaques.; Cerebral cortex (New York, N.Y. : 1991); Vol 17(5). 2007 May.
1. Merigan WH
2. Saunders RC
Unilateral deficits in visual perception and learning after unilateral inferotemporal cortex lesions in macaques.; Cerebral cortex (New York, N.Y. : 1991); Vol 14(8). 2004 Aug.
1. Shimozaki SS
2. Hayhoe MM
3. Zelinsky GJ
4. Weinstein A
5. Merigan WH
6. Ballard DH
Effect of parietal lobe lesions on saccade targeting and spatial memory in a naturalistic visual search task.; Neuropsychologia; Vol 41(10). 2003.
1. Merigan WH
Cortical area V4 is critical for certain texture discriminations, but this effect is not dependent on attention.; Visual neuroscience; Vol 17(6). 2000 Nov.
1. Huxlin KR
2. Saunders RC
3. Marchionini D
4. Pham HA
5. Merigan WH
Perceptual deficits after lesions of inferotemporal cortex in macaques.; Cerebral cortex (New York, N.Y. : 1991); Vol 10(7). 2000 Jul.
1. Merigan WH
Sorting the wheat from the chaff in visual perception.; Nature neuroscience; Vol 2(8). 1999 Aug.
1. Huxlin KR
2. Merigan WH
Deficits in complex visual perception following unilateral temporal lobectomy.; Journal of cognitive neuroscience; Vol 10(3). 1998 May.
1. Merigan WH
2. Pham HA
V4 lesions in macaques affect both single- and multiple-viewpoint shape discriminations.; Visual neuroscience; Vol 15(2). 1998 Mar.
1. Merigan WH
Basic visual capacities and shape discrimination after lesions of extrastriate area V4 in macaques.; Visual neuroscience; Vol 13(1). 1996 Jan.
1. Pasternak T
2. Merigan WH
Motion perception following lesions of the superior temporal sulcus in the monkey.; Cerebral cortex (New York, N.Y. : 1991); Vol 4(3). 1994 May.
1. Merigan WH
2. Nealey TA
3. Maunsell JH
Visual effects of lesions of cortical area V2 in macaques.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 13(7). 1993 Jul.
1. Merigan WH
Colour vision: human V4?; Current biology : CB; Vol 3(4). 1993 Apr 01.
1. Merigan WH
2. Maunsell JH
How parallel are the primate visual pathways?; Annual review of neuroscience; Vol 16. 1993.
1. Lynch JJ
2. Silveira LC
3. Perry VH
4. Merigan WH
Visual effects of damage to P ganglion cells in macaques.; Visual neuroscience; Vol 8(6). 1992 Jun.
1. Merigan WH
2. Byrne CE
3. Maunsell JH
Does primate motion perception depend on the magnocellular pathway?; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 11(11). 1991 Nov.
1. Merigan WH
2. Katz LM
3. Maunsell JH
The effects of parvocellular lateral geniculate lesions on the acuity and contrast sensitivity of macaque monkeys.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 11(4). 1991 Apr.
1. Merigan WH
2. Maunsell JH
Macaque vision after magnocellular lateral geniculate lesions.; Visual neuroscience; Vol 5(4). 1990 Oct.
1. Merigan WH
2. Katz LM
Spatial resolution across the macaque retina.; Vision research; Vol 30(7). 1990.
1. Lynch JJ
2. Eskin TA
3. Merigan WH
Selective degeneration of the parvocellular-projecting retinal ganglion cells in a New World monkey, Saimiri sciureus.; Brain research; Vol 499(2). 1989 Oct 16.
1. Lynch JJ
2. Merigan WH
3. Eskin TA
Subchronic dosing of macaques with 2,5-hexanedione causes long-lasting motor dysfunction but reversible visual loss.; Toxicology and applied pharmacology; Vol 98(1). 1989 Mar 15.
1. Merigan WH
Chromatic and achromatic vision of macaques: role of the P pathway.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 9(3). 1989 Mar.
1. Eskin TA
2. Merigan WH
3. Wood RW
Carbon disulfide effects on the visual system. II. Retinogeniculate degeneration.; Investigative ophthalmology & visual science; Vol 29(4). 1988 Apr.
1. Merigan WH
2. Wood RW
3. Zehl D
4. Eskin TA
Carbon disulfide effects on the visual system. I. Visual thresholds and ophthalmoscopy.; Investigative ophthalmology & visual science; Vol 29(4). 1988 Apr.
1. Eskin TA
2. Merigan WH
Selective acrylamide-induced degeneration of color opponent ganglion cells in macaques.; Brain research; Vol 378(2). 1986 Jul 23.
1. Merigan WH
2. Eskin TA
Spatio-temporal vision of macaques with severe loss of P beta retinal ganglion cells.; Vision research; Vol 26(11). 1986.
1. Pasternak T
2. Flood DG
3. Eskin TA
4. Merigan WH
Selective damage to large cells in the cat retinogeniculate pathway by 2,5-hexanedione.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 5(6). 1985 Jun.
1. Eskin TA
2. Lapham LW
3. Maurissen JP
4. Merigan WH
Acrylamide effects on the macaque visual system. II. Retinogeniculate morphology.; Investigative ophthalmology & visual science; Vol 26(3). 1985 Mar.
1. Merigan WH
2. Barkdoll E
3. Maurissen JP
4. Eskin TA
5. Lapham LW
Acrylamide effects on the macaque visual system. I. Psychophysics and electrophysiology.; Investigative ophthalmology & visual science; Vol 26(3). 1985 Mar.
1. Merigan WH
2. Wood RW
3. Zehl DN
Recent observations on the neurobehavioral toxicity of carbon disulfide.; Neurotoxicology; Vol 6(4). 1985.
1. Pasternak T
2. Merigan WH
Effects of stimulus speed on direction discriminations.; Vision research; Vol 24(10). 1984.
1. Merigan WH
2. Maurissen JP
3. Weiss B
4. Eskin T
5. Lapham LW
Neurotoxic actions of methylmercury on the primate visual system.; Neurobehavioral toxicology and teratology; Vol 5(6). 1983 Nov.
1. Weiss B
2. Wood RW
3. Merigan WH
Toxicity evaluation needs the intact animal.; Annals of the New York Academy of Sciences; Vol 406. 1983.
1. Pasternak T
2. Merigan WH
3. Flood DG
4. Zehl D
The role of area centralis in the spatial vision of the cat.; Vision research; Vol 23(12). 1983.
1. Merigan WH
2. Barkdoll E
3. Maurissen JP
Acrylamide-induced visual impairment in primates.; Toxicology and applied pharmacology; Vol 62(2). 1982 Feb.
1. Pasternak T
2. Movshon JA
3. Merigan WH
Creation of direction selectivity in adult strobe-reared cats.; Nature; Vol 292(5826). 1981 Aug 27.
1. Pasternak T
2. Merigan WH
3. Movshon JA
Motion mechanisms in strobe-reared cats: psychophysical and electrophysical measures.; Acta psychologica; Vol 48(1-3). 1981 Aug.
1. Merigan WH
2. Pasternak T
3. Zehl D
Spatial and temporal vision of macaques after central retinal lesions.; Investigative ophthalmology & visual science; Vol 21(1 Pt 1). 1981 Jul.
1. Pasternak T
2. Merigan WH
The luminance dependence of spatial vision in the cat.; Vision research; Vol 21(9). 1981.
1. Pasternak T
2. Merigan WH
Movement detection by cats: invariance with direction and target configuration.; Journal of comparative and physiological psychology; Vol 94(5). 1980 Oct.
1. Merigan WH
Temporal modulation sensitivity of macaque monkeys.; Vision research; Vol 20(11). 1980.
1. Pasternak T
2. Merigan WH
Abnormal visual resolution of cats reared in stroboscopic illumination.; Nature; Vol 280(5720). 1979 Jul 26.
1. Merigan WH
Effects of toxicants on visual systems.; Neurobehavioral toxicology; Vol 1 Suppl 1. 1979.
1. Laties VG
2. Merigan WH
Behavioral effects of carbon monoxide on animals and man.; Annual review of pharmacology and toxicology; Vol 19. 1979.
1. Smith MD
2. Merigan WH
3. Mcintire RW
Effects of carbon monoxide on fixed-consecutive-number performance in rats.; Pharmacology, biochemistry, and behavior; Vol 5(3). 1976 Sep.
1. Ator NA
2. Merigan WH
3. McIntire RW
The effects of brief exposures to carbon monoxide on temporally differentiated responding.; Environmental research; Vol 12(1). 1976 Aug.
1. Merigan WH
2. McIntire RW
Effects of carbon monoxide on responding under a progressive ratio schedule in rats.; Physiology & behavior; Vol 16(4). 1976 Apr.
1. Merigan WH
The contrast sensitivity of the squirrel monkey (Saimiri sciureus).; Vision research; Vol 16(4). 1976.
1. Merigan WH
2. Miller JS
3. Gollub LR
Short-component multiple schedules: effects of relative reinforcement duration.; Journal of the experimental analysis of behavior; Vol 24(2). 1975 Sep.