Students

Investigating differential intron sensitivity to PUF60, a gene that is deleted or amplified in developmental syndromes and cancers

Interplay Between Glutathione and Hepatic Lipid Metabolism

The Effect of Integrator Subunit 11 Mutations on Integrator Function and Neuronal Development

Investigating the roles of the SF3B1 ULMs in recruiting protein phosphatases for pre-mRNA splicing

 Picking up the Pieces: The Fragmented Process of Cas13 Mediated RNA Cleavage in Human Cells

Development of tools and tRNA-based therapeutics for rescue of PTC-derived disease and improved target protein expression

A UHM-ULM interface contributes to the pre-mRNA splicing functions of U2AF2 and SF3B1

Investigating the Role of RNA Helicases in Splicing Changes caused by Cancer Associated SF3B1 Mutations

Identification and Characterization of Transcription Factors Associating with the Integrator Complex

Structural Characterization of a SIRT6-Nucleosome Array Complex

Modeling CDK12 and CDK13 Loss-of-Function to Investigate Their Roles in Alternative Polyadenylation and Neoantigen Expression

Cytoplasmic binding partners of Integrator endonuclease INTS11 and paralog CPSF73 are required for their nuclear function

Structure and Function Analysis of a Type III PreQ1 Riboswitch from Escherichia coli

Pulling the plug on bacteriophage infection: investigating the molecular mechanism of activation of CRISPR-Csx28

Structure and Function Analysis of a Spermidine-Sensing Bacterial Riboswitch

The Role of the Architectural Transcription Factor HMGN1 in Modulating Inter-nucleosome Interactions

The Role of Histone Modifications and Variants in Longevity of Rodent Species

The role of the Type VI CRISPR-Cas accessory protein Csx27 in CRISPR-Cas13 mediated anti-viral immunity

Defining the roles of 5’UTR length and secondary structure in eukaryotic translation initiation

Targeted tRNA pseudouridylation reveals a novel base interaction that facilitates nonsense suppression

Developing a platform for experimental identification of genetic barriers to horizontal gene transfer in Staphylococcus aureus

Sustainable Degradation of Marine Plastics using Vegetative and Sporulated 3D-Bioprinted Materials

High throughput screening identifies EGLN family prolyl hydroxylases as important determinants of HCMV infection

Regulation of Transcription by the Combination of a KDM5 inhibitor and Decitabine in Breast Cancer

Inhibition of Precancerous Transformation via Drug-Induced p53 Activation

Targeting programmed ribosomal frameshifting in SARS-CoV-2 with a resin-bound dynamic combinatorial library

Novel CRISPR Screening Pipeline identifies JUNB as an Inflammatory Anti-viral Factor

In Vitro Selection Identifies Cardiac Cell Targeting RNA Motifs/p>