Center for Pediatric Biomedical Research - Palis Lab

Publications

  • Malik J, Kim AR, Tyre KA, Cherukuri AR, Palis J.  Erythropoietin critically regulates murine and human primitive erythroblast survival and terminal maturation.  Haematologica, in press, 2013.
  • Kingsley PD, Greenfest-Allen E, Frame JM, Bushnell TP, Malik J, McGrath KE, Stoeckert CJ Jr, Palis J. Ontogeny of erythroid gene expression. Blood 121:e5-e13, 2013.
  • Peslak SA, Wenger J, Bemis JC, Kingsley PD, Koniski AD, McGrath KE, Palis J. EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress. Blood 120:2501-2511, 2012
  • McGrath KE, Frame JM, Fromm GJ, Koniski AD, Kingsley PD, Little J, Bulger M, Palis J. A transient definitive erythroid lineage with unique regulation of the beta-globin locus in the mammalian embryo. Blood 117:4600-4608, 2011.
  • Peslak SA, Wenger J, Bemis JC, Kingsley PD, Koniski AD, Chen Y, Williams JP, McGrath KE, Dertinger SD, Palis J. Sublethal radiation injury uncovers a functional transition during erythroid maturation. Experimental Hematology 39:434-445, 2011.
  • England SJ, McGrath KE, Frame J, Palis J: Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus. Blood, 117:2708-2717, 2011.
  • McGrath KE, Bushnell T, Palis J. Multispectral imaging of hematopoietic cells: where flow meets morphology. Journal of Immunological Methods 336:91-97, 2008.
  • Palis J: Ontogeny of erythropoiesis. Current Opinion in Hematology 15:155-161, 2008.
  • Tober J, McGrath KE, Palis J: Primitive erythropoiesis and megakaryopoiesis in the yolk sac are independent of c-myb. Blood 111:2636-2639, 2008.
  • McGrath KE, Kingsley PD, Koniski AD, Porter RL, Bushnell TP, Palis J: Enucleation of primitive erythroid cells generates a transient population of “pyrenocytes” in the mammalian fetus. Blood 111:2409-2417, 2008.
  • Dertinger S, Tsai Y, Nowak I, Hyrien O, Bemis J, Keng P, Palis J, Chen Y. Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry. Mutation Research 634:119-125, 2007.
  • Tober J, Koniski A, McGrath KE, Vemishetti R, Emerson R, de Mesy-Bentley KKL, Waugh R, Palis J: The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and definitive hematopoiesis. Blood 109:1433-1441, 2007.
  • Kingsley PD, Malik J, Emerson RL, Bushnell TP, McGrath KE, Bloedorn LA, Bulger M, Palis J: “Maturational” globin switching in primary primitive erythroid cells. Blood 107:1667-1672, 2006.
  • McGrath KE, Palis J. Yolk sac hematopoiesis: more than meets the eye.  Experimental Hematology 33:1021-1028, 2005.
  • Huber TL, Kouskoff V,  Fehling HJ, Palis J*, Keller G*. Haemangioblast commitment is initiated in the primitive streak of the mouse embryo. Nature 432:625-630, 2004. (*corresponding authors)
  • Kingsley PD, Malik J, Fantauzzo KA, Palis J: Yolk sac-derived primitive erythroblasts enucleate during mammalian embryogenesis. Blood 104:19-25, 2004. (Plenary paper)
  • McGrath KE, Koniski AD, Malik J, Palis J: Circulation is established in a step-wise pattern in the mammalian embryo. Blood 101:1669-1676, 2003. (Plenary paper)
  • Palis J, Yoder M: Yolk sac hematopoiesis- the first blood cells of mouse and man. Experimental Hematology 29:927-936, 2001.
  • Palis J, Chan RJ, Koniski A, Patel R, Starr M, Yoder MC: Spatial and temporal emergence of high proliferative potential hematopoietic precursors during murine embryogenesis.  Proceedings National Academy of Science USA 98:4528-4533, 2001.
  • Palis J, Kennedy M, Robertson S, Wall C, Keller G: Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse embryo. Development 126:5073-5084, 1999.
  • McGrath KE, Koniski AD, Maltby KM, McGann JK, Palis J: Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4. Developmental Biology 213:442-456, 1999.
  • Palis J, Segel GB: Developmental biology of erythropoiesis. Blood Reviews 12:106-114, 1998.
  • McGrath KE, Palis J: Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation. Molecular Reproduction and Development 48:145-153, 1997.
  • McGann JK, Silver L, Liesveld J, Palis J: Erythropoietin-receptor expression and function during the initiation of murine yolk sac erythropoiesis. Experimental Hematology 25:1149-1157, 1997.
  • Silver L, Palis J: Initiation of murine yolk sac hematopoiesis: a spatial analysis. Blood 89:1154-1164, 1997.
  • Palis J, Kingsley PD, McGrath KE: Initiation of hematopoiesis and vasculogenesis in murine yolk sac explants. Blood 86:156-163, 1995.