Clinical research is facilitated by a perinatal database, a funded General Clinical Research Center, and an NIH supported Clinical and Translation Research Institute.
2007 Abstracts
Advisory Committee Memberships
Current clinical research projects include:
- Ventilatory management of critically ill newborns
- Epidemiology and genetics of prematurity
- Nutrition in low birth weight infants
- Electroencephalographic monitoring of newborns
- Follow-up of high-risk newborns
- Treatment of retinopathy of prematurity (ROP)
- Treatment and prevention of Bronchopulmonary Dysplasia (BPD)
- Immunogenicity of neonatal vaccines
- Study of line-related infections
- Head cooling, for hypoxic-ischemic encephalopathy
- Bilirubin encephalopathy
- Brain development
Laboratory projects seek to apply basic science methodology to problems of clinical importance. Ongoing investigations include:
- Cellular and molecular aspects of development of the lung antioxidant defenses
- The effects of growth factors, oxygen and radiation on lung development
- Mechanical, cellular and molecular mechanisms of lung injury in Bronchopulmonary Dysplasia (BPD)
- Regulation of lung microvascular development and response to injury
- The biophysical properties of surfactant
- Behavioral, morphological and molecular consequences of neonatal hypoxia
- The cellular and molecular pathophysiology of angiogenesis in the developing retina
