Research

Järvinen-Seppo Laboratory

The Center for Food Allergy conducts research through the Järvinen-Seppo Laboratory, which studies the immunologic factors present in human milk and how those factors may modify developing immune systems for infants and their oral tolerance to foods. For more information on our research program and our team members, please visit the Järvinen-Seppo Lab site.

Recent Publications

• 1. Seppo AE
  2. Bu K
  3. Jumabaeva M
  4. Thakar J
  5. Choudhury R
  6. Yonemitsu C
  7. Bode L
  8. Martina CA
  9. Allen M
  10. Tamburini S
  11. Piras E
  12. Wallach DS
  13. Looney RJ
  14. Clemente JC
  15. Järvinen KM
  Infant Gut Microbiome Is Enriched with Bifidobacteria longumssp. infantisin Old Order Mennoniteswith Traditional Farming Lifestyle.; Allergy. 2021 Apr 27.
• 1. Nowak S
  2. Wang H
  3. Schmidt B
  4. Jarvinen KM
  Vitamin D and iron status in food allergic children.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2021 Mar 08.
• 1. Burris AD
  2. Lomas JM
  3. Järvinen KM
  Is It Time to Offer Peanut Oral Immunotherapy to Toddlers?; The journal of allergy and clinical immunology. In practice; Vol 9(3). 2021 Mar.
• 1. Pace RM
  2. Williams JE
  3. Järvinen KM
  4. Belfort MB
  5. Pace CDW
  6. Lackey KA
  7. Gogel AC
  8. Nguyen-Contant P
  9. Kanagaiah P
  10. Fitzgerald T
  11. Ferri R
  12. Young B
  13. Rosen-Carole C
  14. Diaz N
  15. Meehan CL
  16. Caffé B
  17. Sangster MY
  18. Topham D
  19. McGuire MA
  20. Seppo A
  21. McGuire MK
  Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19.; mBio; Vol 12(1). 2021 Feb 09.
• 1. Pier J
  2. Liu EG
  3. Eisenbarth S
  4. Järvinen KM
  The Role of Immunoglobulin A in Oral Tolerance and Food Allergy.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2021 Feb 03.
• 1. Burris AD
  2. Pizzarello C
  3. Järvinen KM
  Immunologic components in human milk and allergic diseases with focus on food allergy.; Seminars in perinatology. 2020 Dec 31.
• 1. Burris AD
  2. Burris J
  3. Järvinen KM
  Cow's Milk Protein Allergy in Term and Preterm Infants: Clinical Manifestations, Immunologic Pathophysiology, and Management Strategies.; NeoReviews; Vol 21(12). 2020 Dec.
• 1. Pace RM
  2. Williams JE
  3. Järvinen KM
  4. Belfort MB
  5. Pace CD
  6. Lackey KA
  7. Gogel AC
  8. Nguyen-Contant P
  9. Kanagaiah P
  10. Fitzgerald T
  11. Ferri R
  12. Young B
  13. Rosen-Carole C
  14. Diaz N
  15. Meehan C
  16. Caffe B
  17. Sangster MY
  18. Topham DJ
  19. McGuire MA
  20. Seppo A
  21. McGuire MK
  COVID-19 and human milk: SARS-CoV-2, antibodies, and neutralizing capacity.; medRxiv : the preprint server for health sciences. 2020 Sep 18.
• 1. Demers-Mathieu V
  2. Do DM
  3. Mathijssen GB
  4. Sela DA
  5. Seppo A
  6. Järvinen KM
  7. Medo E
  Correction: Difference in levels of SARS-CoV-2 S1 and S2 subunits- and nucleocapsid protein-reactive SIgM/IgM, IgG and SIgA/IgA antibodies in human milk.; Journal of perinatology : official journal of the California Perinatal Association. 2020 Sep 16.
• 1. Demers-Mathieu V
  2. Do DM
  3. Mathijssen GB
  4. Sela DA
  5. Seppo A
  6. Järvinen KM
  7. Medo E
  Difference in levels of SARS-CoV-2 S1 and S2 subunits- and nucleocapsid protein-reactive SIgM/IgM, IgG and SIgA/IgA antibodies in human milk.; Journal of perinatology : official journal of the California Perinatal Association. 2020 Sep 01.
• 1. Stern J
  2. Chen M
  3. Jusko TA
  4. Fagnano M
  5. Järvinen KM
  6. Halterman JS
  Food Allergy in At- Risk Adolescents with Asthma: A Key Area for Focus.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2020 Jun 10.
• 1. Lackey KA
  2. Pace RM
  3. Williams JE
  4. Bode L
  5. Donovan SM
  6. Järvinen KM
  7. Seppo AE
  8. Raiten DJ
  9. Meehan CL
  10. McGuire MA
  11. McGuire MK
  SARS-CoV-2 and human milk: What is the evidence?; Maternal & child nutrition. 2020 May 30.
• 1. Burris AD
  2. Wang H
  3. Wilson LM
  4. Jarvinen KM
  5. Lomas J
  Association of oral habits with food allergy and comorbid atopic disease.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2020 May 11.
• 1. Bawany F
  2. Beck LA
  3. Järvinen KM
  Halting the March: Primary Prevention of Atopic Dermatitis and Food Allergies.; The journal of allergy and clinical immunology. In practice; Vol 8(3). 2020 Mar.
• 1. Phillips JT
  2. Stahlhut RW
  3. Looney RJ
  4. Järvinen KM
  Food Allergy, Breastfeeding and Introduction of Complementary Foods in the New York Old Order Mennonites.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2020 Jan 07.
• 1. Soderborg TK
  2. Carpenter CM
  3. Janssen RC
  4. Weir TL
  5. Robertson CE
  6. Ir D
  7. Young BE
  8. Krebs NF
  9. Hernandez TL
  10. Barbour LA
  11. Frank DN
  12. Kroehl M
  13. Friedman JE
  Gestational Diabetes Is Uniquely Associated With Altered Early Seeding of the Infant Gut Microbiota.; Frontiers in endocrinology; Vol 11. 2020.
• 1. McGuire MK
  2. Randall AZ
  3. Seppo AE
  4. Järvinen KM
  5. Meehan CL
  6. Gindola D
  7. Williams JE
  8. Sellen DW
  9. Kamau-Mbuthia EW
  10. Kamundia EW
  11. Mbugua S
  12. Moore SE
  13. Prentice AM
  14. Foster JA
  15. Otoo GE
  16. Rodríguez JM
  17. Pareja RG
  18. Bode L
  19. McGuire MA
  20. Campo JJ
  Multipathogen Analysis of IgA and IgG Antigen Specificity for Selected Pathogens in Milk Produced by Women From Diverse Geographical Regions: The INSPIRE Study.; Frontiers in immunology; Vol 11. 2020.
• 1. Rajani PS
  2. Martin H
  3. Groetch M
  4. Järvinen KM
  Presentation and Management of Food Allergy in Breastfed Infants and Risks of Maternal Elimination Diets.; The journal of allergy and clinical immunology. In practice. 2019 Nov 18.
• 1. Young BE
  2. Borman LL
  3. Heinrich R
  4. Long J
  5. Pinney S
  6. Westcott J
  7. Krebs NF
  Effect of Pooling Practices and Time Postpartum of Milk Donations on the Energy, Macronutrient, and Zinc Concentrations of Resultant Donor Human Milk Pools.; The Journal of pediatrics; Vol 214. 2019 Nov.
• 1. Blyuss O
  2. Cheung KY
  3. Chen J
  4. Parr C
  5. Petrou L
  6. Komarova A
  7. Kokina M
  8. Luzan P
  9. Pasko E
  10. Eremeeva A
  11. Peshko D
  12. Eliseev VI
  13. Pedersen SA
  14. Azad MB
  15. Jarvinen KM
  16. Peroni DG
  17. Verhasselt V
  18. Boyle RJ
  19. Warner JO
  20. Simpson MR
  21. Munblit D
  Statistical Approaches in the Studies Assessing Associations between Human Milk Immune Composition and Allergic Diseases: A Scoping Review.; Nutrients; Vol 11(10). 2019 Oct 10.
• 1. Järvinen KM
  2. Martin H
  3. Oyoshi MK
  Immunomodulatory effects of breast milk on food allergy.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology; Vol 123(2). 2019 Aug.
• 1. Güngör D
  2. Nadaud P
  3. LaPergola CC
  4. Dreibelbis C
  5. Wong YP
  6. Terry N
  7. Abrams SA
  8. Beker L
  9. Jacobovits T
  10. Järvinen KM
  11. Nommsen-Rivers LA
  12. O'Brien KO
  13. Oken E
  14. Pérez-Escamilla R
  15. Ziegler EE
  16. Spahn JM
  Infant milk-feeding practices and food allergies, allergic rhinitis, atopic dermatitis, and asthma throughout the life span: a systematic review.; The American journal of clinical nutrition; Vol 109(Supplement_7). 2019 Mar 01.
• 1. Güngör D
  2. Nadaud P
  3. Dreibelbis C
  4. LaPergola CC
  5. Wong YP
  6. Terry N
  7. Abrams SA
  8. Beker L
  9. Jacobovits T
  10. Järvinen KM
  11. Nommsen-Rivers LA
  12. O'Brien KO
  13. Oken E
  14. Pérez-Escamilla R
  15. Ziegler EE
  16. Spahn JM
  Infant milk-feeding practices and childhood leukemia: a systematic review.; The American journal of clinical nutrition; Vol 109(Supplement_7). 2019 Mar 01.
• 1. Güngör D
  2. Nadaud P
  3. LaPergola CC
  4. Dreibelbis C
  5. Wong YP
  6. Terry N
  7. Abrams SA
  8. Beker L
  9. Jacobovits T
  10. Järvinen KM
  11. Nommsen-Rivers LA
  12. O'Brien KO
  13. Oken E
  14. Pérez-Escamilla R
  15. Ziegler EE
  16. Spahn JM
  Infant milk-feeding practices and cardiovascular disease outcomes in offspring: a systematic review.; The American journal of clinical nutrition; Vol 109(Supplement_7). 2019 Mar 01.
• 1. Güngör D
  2. Nadaud P
  3. Dreibelbis C
  4. LaPergola CC
  5. Wong YP
  6. Terry N
  7. Abrams SA
  8. Beker L
  9. Jacobovits T
  10. Järvinen KM
  11. Nommsen-Rivers LA
  12. O'Brien KO
  13. Oken E
  14. Pérez-Escamilla R
  15. Ziegler EE
  16. Spahn JM
  Infant milk-feeding practices and diagnosed celiac disease and inflammatory bowel disease in offspring: a systematic review.; The American journal of clinical nutrition; Vol 109(Supplement_7). 2019 Mar 01.
• 1. Güngör D
  2. Nadaud P
  3. LaPergola CC
  4. Dreibelbis C
  5. Wong YP
  6. Terry N
  7. Abrams SA
  8. Beker L
  9. Jacobovits T
  10. Järvinen KM
  11. Nommsen-Rivers LA
  12. O'Brien KO
  13. Oken E
  14. Pérez-Escamilla R
  15. Ziegler EE
  16. Spahn JM
  Infant milk-feeding practices and diabetes outcomes in offspring: a systematic review.; The American journal of clinical nutrition; Vol 109(Supplement_7). 2019 Mar 01.
• 1. Seppo AE
  2. Kukkonen AK
  3. Kuitunen M
  4. Savilahti E
  5. Yonemitsu C
  6. Bode L
  7. Järvinen KM
  Association of Maternal Probiotic Supplementation With Human Milk Oligosaccharide Composition.; JAMA pediatrics. 2019 Jan 22.
• 1. Sundquist BK
  2. Jose J
  3. Pauze D
  4. Pauze D
  5. Wang H
  6. Järvinen KM
  Anaphylaxis risk factors for hospitalization and intensive care: A comparison between adults and children in an upstate New York emergency department.; Allergy and asthma proceedings; Vol 40(1). 2019 Jan 01.
• 1. Järvinen KM
  Variations in Human Milk Composition: Impact on Immune Development and Allergic Disease Susceptibility.; Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine; Vol 13(S1). 2018 Apr.
• 1. Bingemann TA
  2. Sood P
  3. Järvinen KM
  Food Protein-Induced Enterocolitis Syndrome.; Immunology and allergy clinics of North America; Vol 38(1). 2018 Feb.
• 1. Rajani PS
  2. Seppo AE
  3. Järvinen KM
  Immunologically Active Components in Human Milk and Development of Atopic Disease, With Emphasis on Food Allergy, in the Pediatric Population.; Frontiers in pediatrics; Vol 6. 2018.
• 1. Järvinen KM
  2. Wang J
  3. Seppo AE
  4. Zand M
  Novel multiplex assay for profiling influenza antibodies in breast milk and serum of mother-infant pairs.; F1000Research; Vol 7. 2018.
• 1. Young BE
  2. Levek C
  3. Reynolds RM
  4. Rudolph MC
  5. MacLean P
  6. Hernandez TL
  7. Friedman JE
  8. Krebs NF
  Bioactive components in human milk are differentially associated with rates of lean and fat mass deposition in infants of mothers with normal vs. elevated BMI.; Pediatric obesity; Vol 13(10). 2018 Jan.
• 1. Young BE
  2. Palmer C
  3. Reynolds R
  4. Rudolph M
  5. MacLean P
  6. Hernandez T
  7. Friedman J
  8. Krebs N
  Bioactive Components in Human Milk are Differentially Associated with Rates of Lean and Fat Mass Deposition in Infants of Normal Weight versus Overweight Mothers.; Pediatric Obesity. 2018 Jan 01.
• 1. Frischmeyer-Guerrerio PA
  2. Masilamani M
  3. Gu W
  4. Brittain E
  5. Wood R
  6. Kim J
  7. Nadeau K
  8. Jarvinen KM
  9. Grishin A
  10. Lindblad R
  11. Sampson HA
  Mechanistic correlates of clinical responses to omalizumab in the setting of oral immunotherapy for milk allergy.; The Journal of allergy and clinical immunology; Vol 140(4). 2017 Oct.