Golisano Children's Hospital / Pediatric Allergy/Immunology / Center for Food Allergy / Research

Research

Järvinen-Seppo Laboratory

The Center for Food Allergy conducts research through the Järvinen-Seppo Laboratory, which studies the immunologic factors present in human milk and how those factors may modify developing immune systems for infants and their oral tolerance to foods. For more information on our research program and our team members, please visit the Järvinen-Seppo Lab site.

Recent Publications

Young BE, Seppo AE, Diaz N, Rosen-Carole C, Nowak-Wegrzyn A, Cruz Vasquez JM, Ferri-Huerta R, Nguyen-Contant P, Fitzgerald T, Sangster MY, Topham DJ, Järvinen KM. Association of Human Milk Antibody Induction, Persistence, and Neutralizing Capacity With SARS-CoV-2 Infection vs mRNA Vaccination; JAMA Pediatr. 2021 Nov 10.

1. Young BE
2. Seppo AE
3. Diaz N
4. Rosen-Carole C
5. Nowak-Wegrzyn A
6. Cruz Vasquez JM
7. Ferri-Huerta R
8. Nguyen-Contant P
9. Fitzgerald T
10. Sangster MY
11. Topham DJ
12. Järvinen KM
Association of Human Milk Antibody Induction, Persistence, and Neutralizing Capacity With SARS-CoV-2 Infection vs mRNA Vaccination.; JAMA pediatrics. 2021 Nov 10.
1. Callahan EA
2. Chatila T
3. Deckelbaum RJ
4. Field CJ
5. Greer FR
6. Hernell O
7. Järvinen KM
8. Kleinman RE
9. Milner J
10. Neu J
11. Smolen KK
12. Wallingford JC
Assessing the safety of bioactive ingredients in infant formula that affect the immune system: Recommendations from an expert panel.; The American journal of clinical nutrition. 2021 Oct 11.
1. Jackson CM
2. Mahmood MM
3. Järvinen KM
Farming lifestyle and human milk: modulation of the infant microbiome and protection against allergy.; Acta paediatrica (Oslo, Norway : 1992). 2021 Oct 09.
1. Rodel RL
2. Farabi SS
3. Hirsch NM
4. Rolloff KP
5. McNair B
6. Hernandez TL
7. Krebs NF
8. Barbour LA
9. Young BE
Human milk imparts higher insulin concentration in infants born to women with type 2 diabetes mellitus.; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2021 Aug 31.
1. Seppo AE
2. Bu K
3. Jumabaeva M
4. Thakar J
5. Choudhury R
6. Yonemitsu C
7. Bode L
8. Martina CA
9. Allen M
10. Tamburini S
11. Piras E
12. Wallach DS
13. Looney RJ
14. Clemente JC
15. Järvinen KM
Infant Gut Microbiome Is Enriched with Bifidobacteria longumssp. infantisin Old Order Mennoniteswith Traditional Farming Lifestyle.; Allergy. 2021 Apr 27.
1. Azad MB
2. Nickel NC
3. Bode L
4. Brockway M
5. Brown A
6. Chambers C
7. Goldhammer C
8. Hinde K
9. McGuire M
10. Munblit D
11. Patel AL
12. Pérez-Escamilla R
13. Rasmussen KM
14. Shenker N
15. Young BE
16. Zuccolo L
Breastfeeding and the origins of health: Interdisciplinary perspectives and priorities.; Maternal & child nutrition; Vol 17(2). 2021 Apr.
1. Nowak S
2. Wang H
3. Schmidt B
4. Jarvinen KM
Vitamin D and iron status in food allergic children.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2021 Mar 08.
1. Burris AD
2. Lomas JM
3. Järvinen KM
Is It Time to Offer Peanut Oral Immunotherapy to Toddlers?; The journal of allergy and clinical immunology. In practice; Vol 9(3). 2021 Mar.
1. Schinkel ER
2. Nelson ER
3. Young BE
4. Bernstein RM
5. Taylor SN
6. Brown LD
7. Hay WW
8. Brown KJ
9. Prenni J
Concentrating human milk: an innovative point-of-care device designed to increase human milk feeding options for preterm infants.; Journal of perinatology : official journal of the California Perinatal Association; Vol 41(3). 2021 Mar.
1. Pace RM
2. Williams JE
3. Järvinen KM
4. Belfort MB
5. Pace CDW
6. Lackey KA
7. Gogel AC
8. Nguyen-Contant P
9. Kanagaiah P
10. Fitzgerald T
11. Ferri R
12. Young B
13. Rosen-Carole C
14. Diaz N
15. Meehan CL
16. Caffé B
17. Sangster MY
18. Topham D
19. McGuire MA
20. Seppo A
21. McGuire MK
Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19.; mBio; Vol 12(1). 2021 Feb 09.
1. Pier J
2. Liu EG
3. Eisenbarth S
4. Järvinen KM
The Role of Immunoglobulin A in Oral Tolerance and Food Allergy.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2021 Feb 03.
1. Seppo AE
2. Choudhury R
3. Pizzarello C
4. Palli R
5. Fridy S
6. Rajani PS
7. Stern J
8. Martina C
9. Yonemitsu C
10. Bode L
11. Bu K
12. Tamburini S
13. Piras E
14. Wallach DS
15. Allen M
16. Looney RJ
17. Clemente JC
18. Thakar J
19. Järvinen KM
Traditional Farming Lifestyle in Old Older Mennonites Modulates Human Milk Composition.; Frontiers in immunology; Vol 12. 2021.
1. Pace RM
2. Williams JE
3. Järvinen KM
4. Meehan CL
5. Martin MA
6. Ley SH
7. Barbosa-Leiker C
8. Andres A
9. Yeruva L
10. Belfort MB
11. Caffé B
12. Navarrete AD
13. Lackey KA
14. Pace CDW
15. Gogel AC
16. Fehrenkamp BD
17. Klein M
18. Young BE
19. Rosen-Carole C
20. Diaz N
21. Gaw SL
22. Flaherman V
23. McGuire MA
24. McGuire MK
25. Seppo AE
Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies.; Frontiers in immunology; Vol 12. 2021.
1. Young BE
2. Westcott J
3. Kemp J
4. Allen L
5. Hampel D
6. Garcés AL
7. Figueroa L
8. Goudar SS
9. Dhaded SM
10. Somannavar M
11. Saleem S
12. Ali SA
13. Hambidge KM
14. Krebs NF
B-Vitamins and Choline in Human Milk Are Not Impacted by a Preconception Lipid-Based Nutrient Supplement, but Differ Among Three Low-to-Middle Income Settings-Findings From the Women First Trial.; Frontiers in nutrition; Vol 8. 2021.
1. Burris AD
2. Pizzarello C
3. Järvinen KM
Immunologic components in human milk and allergic diseases with focus on food allergy.; Seminars in perinatology. 2020 Dec 31.
1. Burris AD
2. Burris J
3. Järvinen KM
Cow's Milk Protein Allergy in Term and Preterm Infants: Clinical Manifestations, Immunologic Pathophysiology, and Management Strategies.; NeoReviews; Vol 21(12). 2020 Dec.
1. Pace RM
2. Williams JE
3. Järvinen KM
4. Belfort MB
5. Pace CD
6. Lackey KA
7. Gogel AC
8. Nguyen-Contant P
9. Kanagaiah P
10. Fitzgerald T
11. Ferri R
12. Young B
13. Rosen-Carole C
14. Diaz N
15. Meehan C
16. Caffe B
17. Sangster MY
18. Topham DJ
19. McGuire MA
20. Seppo A
21. McGuire MK
COVID-19 and human milk: SARS-CoV-2, antibodies, and neutralizing capacity.; medRxiv : the preprint server for health sciences. 2020 Sep 18.
1. Demers-Mathieu V
2. Do DM
3. Mathijssen GB
4. Sela DA
5. Seppo A
6. Järvinen KM
7. Medo E
Correction: Difference in levels of SARS-CoV-2 S1 and S2 subunits- and nucleocapsid protein-reactive SIgM/IgM, IgG and SIgA/IgA antibodies in human milk.; Journal of perinatology : official journal of the California Perinatal Association. 2020 Sep 16.
1. Demers-Mathieu V
2. Do DM
3. Mathijssen GB
4. Sela DA
5. Seppo A
6. Järvinen KM
7. Medo E
Difference in levels of SARS-CoV-2 S1 and S2 subunits- and nucleocapsid protein-reactive SIgM/IgM, IgG and SIgA/IgA antibodies in human milk.; Journal of perinatology : official journal of the California Perinatal Association. 2020 Sep 01.
1. Stern J
2. Chen M
3. Jusko TA
4. Fagnano M
5. Järvinen KM
6. Halterman JS
Food Allergy in At- Risk Adolescents with Asthma: A Key Area for Focus.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2020 Jun 10.
1. Lackey KA
2. Pace RM
3. Williams JE
4. Bode L
5. Donovan SM
6. Järvinen KM
7. Seppo AE
8. Raiten DJ
9. Meehan CL
10. McGuire MA
11. McGuire MK
SARS-CoV-2 and human milk: What is the evidence?; Maternal & child nutrition. 2020 May 30.
1. Burris AD
2. Wang H
3. Wilson LM
4. Jarvinen KM
5. Lomas J
Association of oral habits with food allergy and comorbid atopic disease.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2020 May 11.
1. Bawany F
2. Beck LA
3. Järvinen KM
Halting the March: Primary Prevention of Atopic Dermatitis and Food Allergies.; The journal of allergy and clinical immunology. In practice; Vol 8(3). 2020 Mar.
1. Phillips JT
2. Stahlhut RW
3. Looney RJ
4. Järvinen KM
Food Allergy, Breastfeeding and Introduction of Complementary Foods in the New York Old Order Mennonites.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2020 Jan 07.
1. Soderborg TK
2. Carpenter CM
3. Janssen RC
4. Weir TL
5. Robertson CE
6. Ir D
7. Young BE
8. Krebs NF
9. Hernandez TL
10. Barbour LA
11. Frank DN
12. Kroehl M
13. Friedman JE
Gestational Diabetes Is Uniquely Associated With Altered Early Seeding of the Infant Gut Microbiota.; Frontiers in endocrinology; Vol 11. 2020.
1. McGuire MK
2. Randall AZ
3. Seppo AE
4. Järvinen KM
5. Meehan CL
6. Gindola D
7. Williams JE
8. Sellen DW
9. Kamau-Mbuthia EW
10. Kamundia EW
11. Mbugua S
12. Moore SE
13. Prentice AM
14. Foster JA
15. Otoo GE
16. Rodríguez JM
17. Pareja RG
18. Bode L
19. McGuire MA
20. Campo JJ
Multipathogen Analysis of IgA and IgG Antigen Specificity for Selected Pathogens in Milk Produced by Women From Diverse Geographical Regions: The INSPIRE Study.; Frontiers in immunology; Vol 11. 2020.
1. Young BE
2. Murphy K
3. Borman LL
4. Heinrich R
5. Krebs NF
Milk Bank Pooling Practices Impact Concentrations and Variability of Bioactive Components of Donor Human Milk.; Frontiers in nutrition; Vol 7. 2020.
1. Rajani PS
2. Martin H
3. Groetch M
4. Järvinen KM
Presentation and Management of Food Allergy in Breastfed Infants and Risks of Maternal Elimination Diets.; The journal of allergy and clinical immunology. In practice. 2019 Nov 18.
1. Young BE
2. Borman LL
3. Heinrich R
4. Long J
5. Pinney S
6. Westcott J
7. Krebs NF
Effect of Pooling Practices and Time Postpartum of Milk Donations on the Energy, Macronutrient, and Zinc Concentrations of Resultant Donor Human Milk Pools.; The Journal of pediatrics; Vol 214. 2019 Nov.
1. Blyuss O
2. Cheung KY
3. Chen J
4. Parr C
5. Petrou L
6. Komarova A
7. Kokina M
8. Luzan P
9. Pasko E
10. Eremeeva A
11. Peshko D
12. Eliseev VI
13. Pedersen SA
14. Azad MB
15. Jarvinen KM
16. Peroni DG
17. Verhasselt V
18. Boyle RJ
19. Warner JO
20. Simpson MR
21. Munblit D
Statistical Approaches in the Studies Assessing Associations between Human Milk Immune Composition and Allergic Diseases: A Scoping Review.; Nutrients; Vol 11(10). 2019 Oct 10.
1. Järvinen KM
2. Martin H
3. Oyoshi MK
Immunomodulatory effects of breast milk on food allergy.; Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology; Vol 123(2). 2019 Aug.
1. Güngör D
2. Nadaud P
3. LaPergola CC
4. Dreibelbis C
5. Wong YP
6. Terry N
7. Abrams SA
8. Beker L
9. Jacobovits T
10. Järvinen KM
11. Nommsen-Rivers LA
12. O'Brien KO
13. Oken E
14. Pérez-Escamilla R
15. Ziegler EE
16. Spahn JM
Infant milk-feeding practices and food allergies, allergic rhinitis, atopic dermatitis, and asthma throughout the life span: a systematic review.; The American journal of clinical nutrition; Vol 109(Supplement_7). 2019 Mar 01.
1. Güngör D
2. Nadaud P
3. Dreibelbis C
4. LaPergola CC
5. Wong YP
6. Terry N
7. Abrams SA
8. Beker L
9. Jacobovits T
10. Järvinen KM
11. Nommsen-Rivers LA
12. O'Brien KO
13. Oken E
14. Pérez-Escamilla R
15. Ziegler EE
16. Spahn JM
Infant milk-feeding practices and childhood leukemia: a systematic review.; The American journal of clinical nutrition; Vol 109(Supplement_7). 2019 Mar 01.
1. Güngör D
2. Nadaud P
3. LaPergola CC
4. Dreibelbis C
5. Wong YP
6. Terry N
7. Abrams SA
8. Beker L
9. Jacobovits T
10. Järvinen KM
11. Nommsen-Rivers LA
12. O'Brien KO
13. Oken E
14. Pérez-Escamilla R
15. Ziegler EE
16. Spahn JM
Infant milk-feeding practices and cardiovascular disease outcomes in offspring: a systematic review.; The American journal of clinical nutrition; Vol 109(Supplement_7). 2019 Mar 01.
1. Güngör D
2. Nadaud P
3. Dreibelbis C
4. LaPergola CC
5. Wong YP
6. Terry N
7. Abrams SA
8. Beker L
9. Jacobovits T
10. Järvinen KM
11. Nommsen-Rivers LA
12. O'Brien KO
13. Oken E
14. Pérez-Escamilla R
15. Ziegler EE
16. Spahn JM
Infant milk-feeding practices and diagnosed celiac disease and inflammatory bowel disease in offspring: a systematic review.; The American journal of clinical nutrition; Vol 109(Supplement_7). 2019 Mar 01.