Our research has improved the health of children. A century ago, children routinely died of infections and nutritional deficiencies. A little over a decade ago there were very few treatment options for childhood cancer, premature birth, and congenital heart or brain diseases. Although our research has made significant strides in these areas, our work is far from finished. Now our challenge is to help young patients live healthier lives as they move into adulthood. Our goals for the future are to prevent childhood diseases, limit complications from treatment, and effectively manage chronic illnesses.