Skip to main content
Explore URMC

Golisano Children's Hospital Logo

menu
Pediatrics / Jarvinen-Seppo Lab / Clinical Studies / Infant Immunity Study

Infant Immunity Study

Do You Have Allergies in the Family and Are You Pregnant?

Pregnant womanWe Are Looking for Study Participants

Allergic diseases have dramatically increased in the last 20 years. We want to find out why and learn how to prevent them.

Eligible Study Participants

If you, your partner or your child has eczema, hay fever, asthma or allergies, you may qualify for our study. You need to be 18 years or older, healthy and pregnant.

This is a 2-year study for mothers & their infants collecting questionnaires and samples (stool, saliva, etc.).

You will be reimbursed for your time and allergy evaluation will be provided as appropriate.

The Study

The bacteria that live in our bodies, called microbiome, play a critical role in the development of the immune system. Changes in the microbiome almost certainly play an important role in the rise of allergic and autoimmune diseases in developed countries.

We will study the development of the infant immune system in people at high risk and in those at low risk for allergic diseases.

The Old Order Mennonites have a very low risk for allergic diseases, asthma and a lifestyle related with various microbiome exposure; high-risk people include families with allergic parents and children.

These studies will provide new knowledge about the development of immunity, and set the groundwork for future studies in the prevention of allergic diseases in childhood.

Visits and Test Schedules

Mother’s Samples

Screening Visit

  • Nasal swab
  • Urine
  • Blood draw

Visit 1 (Day of Labor/Day 1-5)

  • Breastmilk sample
  • Cord blood sample

Visit 2 (Week 6)

  • Breastmilk sample
  • Saliva
  • Blood draw
  • Stool sample
  • Skin swab

Visit 3 (Month 4-6)

  • Breastmilk sample

 

Questionnaires completed at:

  • Screening
  • Visits 2, 3, 4, 5 and 6

Home Dust collection – randomly selected

  • Collected once during study

Telephone Contacts

  • Contacted at Months 9, 15 and 21

Infant’s Samples

Visit 2 (Week 6)

  • Saliva
  • Stool
  • Skin swab
  • Nasal swab
  • Buccal swab (optional)

Visit 3 (Month 4-6)

  • Saliva
  • Blood draw
  • Stool
  • Skin swab
  • Nasal swab

Visit 4 (Month 12)

  • Saliva
  • Blood draw
  • Stool
  • Skin swab
  • Nasal swab

Visit 5 (Month 18)

  • Saliva Stool
  • Nasal swab

Visit 6 (Month 24)

  • Saliva
  • Nasal swab
  • Blood draw
  • Stool
  • Skin swab

Contact Us

For more information please call Barbara Johnson, RN Coordinator.

Tel: (585) 275-8991
eMail: InfantAllergyStudy@URMC.Rochester.edu

This study is sponsored by the National Institutes of Health.