Development of Mucosal and Systemic Immunity and Risk of Food Allergy
The “Development of Mucosal and Systemic Immunity and Risk of Food Allergy” study is recruiting mother-infant pairs prenatally or immediately postnatally for a cohort study to assess the development of microbiome, infant immune system and allergic diseases in the first 2 years of life. We are interested in enrolling infants born to families with a parent(s) or older sibling(s) with allergic diseases, especially food allergy, in the Greater Rochester area. We are also enrolling infants born in the Old Order Mennonite community in Penn Yan, the Yates County (Finger Lakes), who have a low risk of developing allergic diseases. Interested participants may call our research coordinator, Barbara Johnson, R.N. at (585) 275-8991.
Does Breast Milk Offer Protection from Infectious Diseases in Infants?
Kirsi Järvinen-Seppo, M.D., Ph.D., associate professor of Pediatric Allergy/Immunology, received a $1.5 million grant from the Bill & Melinda Gates Foundation. The grant will fund an initiative to explore whether breast milk can offer infants protection from infectious diseases. Researchers will analyze breast milk samples from different geographical areas of the world to determine whether certain antibodies are passed from mothers to infants through breast milk.
Five research institutions are involved in the initiative and URMC was selected as the coordinating center for the project.
PI: Kirsi Jarvinen-Seppo, M.D., Ph.D.
Funding Agency: Bill & Melinda Gates Foundation
Award Title: “Immunoprofiling of IgA & IgG Specific to Pathogens in Colostrum and Mature Milk Between Geographic Locations and in Association with Maternal Nutritional Status and Infant Diarrheal and Respiratory Outcomes”
Dates: 09/25/17 – 09/30/18
Total Award: $1,510,535.