News

Jun. 15, 2022

Developmental Role of Three Systems - Co-development of Gut Microbiome, Respiratory and Immune Systems

Co-development of Gut Microbiome, Respiratory and Immune Systems Directly Impact Baby's Development

A new multidisciplinary study conducted by Kristin Scheible and Andrew McDavid, researchers at the University of Rochester Medical Center, has found that the co-development of three systems, the gut microbiome, respiratory system and immune system, is correlated with a baby's respiratory health, and an infant can have negative respiratory outcomes if the development of one of these systems is disrupted.

The study, “Aberrant newborn T cell and microbiota developmental trajectories predict respiratory compromise during infancy,” was published in iScience (Cell Press) and was co-authored by Kristin Scheible, M.D., associate professor in the departments of Pediatrics and Microbiology and Immunology, and Andrew McDavid, Ph.D., from the department of Biostatistics and Computational Biology.