Lab Members
Principal Investigator
Our lab seeks to elucidate the molecular programs that determine age-related immune cell-intrinsic behavior, the specific pathways through which early exposures disrupt normal immune development, and finally, the clinical consequences of abnormal immune development during infancy.
Dr. Scheible is a member of the Society for Pediatric Research and fellow, of the American Academy of Pediatrics.
Nathan Laniewski
Senior Technical Associate/Lab Manager
It’s all about the “ABCs” – “Always be clustering!”
I develop wet-bench and bioinformatics workflows to generate and analyze single cell data (flow/mass cytometry). Due to a surprising amount of heterogeneity among immune cell subsets – even in “naïve” neonates – high-dimensional clustering techniques are needed to efficiently profile and characterize these cells.
Darline Castro-Melendez, Ph.D.
Postdoctoral Associate
Environmental exposures and the neonatal immune system
I am fortunate to carry out an exciting research project defining the relationship between Per-and Polyfluoroalkyl Substances (PFAS) on the developing neonatal immune system. I am applying a systems immunology approach to determine the relationship between PFAS exposure in utero and infant T cell phenotype and function postnatally using high-dimensional analysis.
Janiret Narvaez-Miranda, Ph.D.
Postdoctoral Associate
Infant’s Gut Microbiome and Vaccine responses
As a translational sciences graduate student, my goal in the lab is to bring observations made in the lab from “Bench to Bedside.” My project evaluates the relationship between the infant gut microbiome and rotavirus vaccine responses and assesses breast milk exposure's potential impact on this relationship.
Brandon Groff
PhD Candidate, Translational Biomedical Science Graduate Program
He studies the cell-intrinsic molecular programming that distinguishes CD8+ T cell subsets during early human development.
Jordan McMurry
MD/PhD Candidate, Pathology Graduate Program
She studies the functional differences and molecular programming related to conventional naïve CD4+ T cells during early human development.
Kelechi Ejiofor
Undergraduate Student, University of Rochester, Computational Biology and Translational Science major
Kelechi is investigating the role of early microbial gut colonization on gamma delta T cell maturation in human infants.