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Kristin Scheible, M.D.

Contact Information

Phone Numbers

Office: (585) 275-2972

Fax: (585) 756-7780

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Research Labs

Faculty Appointments

Patient Care Setting

Pediatrics

Biography

As a neonatologist, Dr. Scheible's first and foremost goal is to provide excellent clinical care to her patients. She believes it is critical to work collaboratively with parents and bedside care providers to achieve the best outcomes for our babies, even in highly complex clinical situations. She encourages her care team to incorporate parental concerns into their daily assessment. By doing so, they can have a complete understanding of the patient's condition not just based on objective data available to us, but also the more subtle, and difficult to gather, "intuition" that only a parent can provide.

As part of the extracorporeal membrane oxygenation team (ECMO) team, Dr. Scheible has a special interest in caring for babies with persistent pulmonary hypertension, who struggle with adapting their circulation to an ex-utero environment. The complex, labile physiology and individual variability that such babies experience is exceptionally challenging, and requires an intensive, interdisciplinary approach to help them transition.

She feels that as neonatologists her job is not to just address the immediate problem, but also understand the long-term risks and benefits of each of our treatments. For her, balancing these short and long term goals, in cooperation with the parents and care team, is the most difficult and rewarding aspect of being a Neonatologist.

Dr. Scheible has received the "Patient and Family Centered Care Award" and holds "Bronze Star" level which is direct recognition from the families and patients in which she serves.

Research

Advanced NICU care has improved survival of very premature infants, but their improved survival is accompanied by long-term complications such as impaired lung function. Infants born prematurely are highly susceptible to recurrent, severe respiratory viruses, suggesting a state of immune deficiency, specifically T cell immunity. They also suffer from diseases characterized by chronic inflammation associated with T cell activation, including bronchopulmonary dysplasia. This clinical paradox (T cells able to activate but not protect) is not well explained.

Our lab is interested in understanding the specific ways in which premature birth disrupts normal T cell development, and the impact of abnormal T cell development on a premature infant's clinical outcomes. Our lab primarily uses high parameter flow cytometric and high-throughput sequencing approaches to interrogate T cell receptor, cytokine signaling and functional differences that are intrinsic to T cells in various stages of fetal development. We work closely with investigators in Neonatology, Obstetrics, Infectious Diseases, Microbiology, Immunology, Genetics, Biostatistics and Computational Biology to understand in vitro T cell behavior in the context of longitudinal, translational human studies, including the Prematurity and Respiratory Outcomes Program and Respiratory Pathogens Research Center.

Dr. Scheible is a member of the Society for Pediatric Research and fellow, of the American Academy of Pediatrics.

Credentials

Education

2004
MD | University of Rochester School of Medicine/Dentistry

Post-doctoral Training & Residency

07/01/2007 - 06/30/2010
Fellowship in Neonatology at University of Rochester Medical Center

07/01/2005 - 06/30/2007
Residency in Pediatrics at University of Rochester Medical Center

06/15/2004 - 06/30/2005
Internship in Pediatrics at University of Rochester Medical Center

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Awards

2017
American Thoracic Society Abstract Award

2014
University of Rochester Bronze Star
Location: University of Rochester

2013
Patient-and Family-Centered Care Award

2012
Patient-and Family-Centered Care Award

2011 - 2016
University of Rochester Strong Star
Location: University of Rochester

2011
Pediatric Research Society, Young Investigator

2009
NICHD Fellows Conference (nominated/selected attendee)

2008 - 2011
Ruth L. Kirschstein National Research Service Award, (T32, Francis Gigliotti)

2004
Janet M. Glascow Memorial Achievement Award
Sponsor: University of Rochester School of Medicine and Dentistry
Location: Rochester, NY

2000
Summer Fellowship in Anesthesiology

1993
Outstanding Graduate in the Faculty of Arts and Letters
Sponsor: SUNY Buffalo
Location: Buffalo, NY

1993
Lucia Maria Haupt Award in Anthropology
Sponsor: SUNY Buffalo
Location: Buffalo, NY

1991
Kreyer Prize for Excellence in German
Location: University of Rochester

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Publications

Journal Articles

3/23/2023
Maurya P, Ture SK, Li C, Scheible KM, McGrath KE, Palis J, Morrell CN. "Transfusion of Adult, but Not Neonatal, Platelets Promotes Monocyte Trafficking in Neonatal Mice." Arteriosclerosis, thrombosis, and vascular biology.. 2023 Mar 23; Epub 2023 Mar 23.

2/1/2023
Hudak ML, Flannery DD, Barnette K, Getzlaff T, Gautam S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Ellington SR, Galang RR, Snead MC, Woodworth KR, Zapata LB, Puopolo KM, . "Maternal and Newborn Hospital Outcomes of Perinatal SARS-CoV-2 Infection: A National Registry." Pediatrics.. 2023 Feb 1; 151(2)

11/8/2022
Peterson LS, Scheible K. "Leveraging Microbial Symbiosis to Modulate Bronchopulmonary Dysplasia." American journal of respiratory cell and molecular biology.. 2022 Nov 8; Epub 2022 Nov 08.

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