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Kristin Scheible, M.D.

Contact Information

Phone Numbers

Office: (585) 275-2972

Fax: (585) 756-7780

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Research Labs

Faculty Appointments

Patient Care Setting



As a neonatologist, Dr. Scheible's first and foremost goal is to provide excellent clinical care to her patients. She believes it is critical to work collaboratively with parents and bedside care providers to achieve the best outcomes for our babies, even in highly complex clinical situations. She encourages her care team to incorporate parental concerns into their daily assessment. By doing so, they can have a complete understanding of the patient's condition not just based on objective data available to us, but also the more subtle, and difficult to gather, "intuition" that only a parent can provide.

As part of the extracorporeal membrane oxygenation team (ECMO) team, Dr. Scheible has a special interest in caring for babies with persistent pulmonary hypertension, who struggle with adapting their circulation to an ex-utero environment. The complex, labile physiology and individual variability that such babies experience is exceptionally challenging, and requires an intensive, interdisciplinary approach to help them transition.

She feels that as neonatologists her job is not to just address the immediate problem, but also understand the long-term risks and benefits of each of our treatments. For her, balancing these short and long term goals, in cooperation with the parents and care team, is the most difficult and rewarding aspect of being a Neonatologist.

Dr. Scheible has received the "Patient and Family Centered Care Award" and holds "Bronze Star" level which is direct recognition from the families and patients in which she serves.


Advanced NICU care has improved survival of very premature infants, but their improved survival is accompanied by long-term complications such as impaired lung function. Infants born prematurely are highly susceptible to recurrent, severe respiratory viruses, suggesting a state of immune deficiency, specifically T cell immunity. They also suffer from diseases characterized by chronic inflammation associated with T cell activation, including bronchopulmonary dysplasia. This clinical paradox (T cells able to activate but not protect) is not well explained.

Our lab is interested in understanding the specific ways in which premature birth disrupts normal T cell development, and the impact of abnormal T cell development on a premature infant's clinical outcomes. Our lab primarily uses high parameter flow cytometric and high-throughput sequencing approaches to interrogate T cell receptor, cytokine signaling and functional differences that are intrinsic to T cells in various stages of fetal development. We work closely with investigators in Neonatology, Obstetrics, Infectious Diseases, Microbiology, Immunology, Genetics, Biostatistics and Computational Biology to understand in vitro T cell behavior in the context of longitudinal, translational human studies, including the Prematurity and Respiratory Outcomes Program and Respiratory Pathogens Research Center.

Dr. Scheible is a member of the Society for Pediatric Research and fellow, of the American Academy of Pediatrics.



  • Neonatal-Perinatal Medicine - American Board of Pediatrics
  • Pediatrics


BA | State University at Buffalo
Anthropology and Women's Studies

MD | University of Rochester School of Medicine & Dentistry

Post-doctoral Training & Residency

07/01/2007 - 06/30/2010
Fellowship in Neonatology at University of Rochester Medical Center - GME Office

07/01/2005 - 06/30/2007
Residency in Pediatrics at University of Rochester Medical Center - GME Office

06/15/2004 - 06/30/2005
Internship in Pediatrics at University of Rochester Medical Center - GME Office

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American Thoracic Society Abstract Award

University of Rochester Bronze Star
Location: University of Rochester

Patient-and Family-Centered Care Award

Patient-and Family-Centered Care Award

2011 - 2016
University of Rochester Strong Star
Location: University of Rochester

Pediatric Research Society, Young Investigator

NICHD Fellows Conference (nominated/selected attendee)

2008 - 2011
Ruth L. Kirschstein National Research Service Award, (T32, Francis Gigliotti)

Janet M. Glascow Memorial Achievement Award
Sponsor: University of Rochester School of Medicine and Dentistry
Location: Rochester, NY

Summer Fellowship in Anesthesiology

Outstanding Graduate in the Faculty of Arts and Letters
Sponsor: SUNY Buffalo
Location: Buffalo, NY

Lucia Maria Haupt Award in Anthropology
Sponsor: SUNY Buffalo
Location: Buffalo, NY

Kreyer Prize for Excellence in German
Location: University of Rochester

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Journal Articles

Keller RL, Feng R, DeMauro SB, Ferkol T, Hardie W, Rogers EE, Stevens TP, Voynow JA, Bellamy SL, Shaw PA, Moore PE,. "Prematurity and Respiratory Outcomes Program. Bronchopulmonary dysplasia and perinatal characteristics predict 1-year respiratory outcomes in newborns born at extremely low gestational age: A prospective cohort study." 2017; .

Szafranski P, Gambin T, Dharmadhikari AV, Akdemir KC, Jhangiani SN, Schuette J, Godiwala N, Yatsenko SA, Sebastian J, Madan-Khetarpal S, Surti U, Abellar RG, Bateman DA, Wilson AL, Markham MH, Slamon J, Santos-Simarro F, Palomares M, Nevado J, Lapunzina P, Chung BH, Wong WL, Chu YW, Mok GT, Kerem E, Reiter J, Ambalavanan N, Anderson SA, Kelly DR, Shieh J, Rosenthal TC, Scheible K, Steiner L, Iqbal MA, McKinnon ML, Hamilton SJ, Schlade-Bartusiak K, English D, Hendson G, Roeder ER, DeNapoli TS, Littlejohn RO, Wolff DJ, Wagner CL, Yeung A, Francis D, Fiorino EK, Edelman M, Fox J, Hayes DA, Janssens S, De Baere E, Menten B, Loccufier A, Vanwalleghem L, Moerman P, Sznajer Y, Lay AS, Kussmann JL, Chawla J, Payton DJ, Phillips GE, Brosens E, Tibboel D, de Klein A, Maystadt I, Fisher R, Sebire N, Male A, Chopra M, Pinner J, Malcolm G, Peters G, Arbuckle S, Lees M, Mead Z, Quarrell O, Sayers R, Owens M, Shaw-Smith C, Lioy J, McKay E, de Leeuw N, Feenstra I, Spruijt L, Elmslie F, Thiruchelvam T, Bacino CA, Langston C, Lupski JR, Sen P, Popek E, Stankiewicz P. "Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins." Human genetics.. 2016 May 0; 135(5):569-86. Epub 2016 Apr 12.

Scheible KM, Emo J, Yang H, Holden-Wiltse J, Straw A, Huyck H, Misra S, Topham DJ, Ryan RM, Reynolds AM, Mariani TJ, Pryhuber GS. "Developmentally determined reduction in CD31 during gestation is associated with CD8+ T cell effector differentiation in preterm infants." Clinical immunology : the official journal of the Clinical Immunology Society.. 2015 Dec 0; 161(2):65-74. Epub 2015 Jul 29.