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Edward E. Walsh, M.D.

Edward E. Walsh, M.D.

Infectious Disease

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
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About Me

Certified Specialties

Infectious Disease - American Board of Internal Medicine

Internal Medicine - American Board of Internal Medicine

Faculty Appointments

Professor - Department of Medicine, Infectious Diseases (SMD)

Credentials

Residency & Fellowship

Fellowship, Infectious Disease, University of Rochester Medical Center. 1980 - 1982

Residency, Infectious Disease, University of Rochester Medical Center. 1975 - 1977

Internship, Internal Medicine, University of Rochester Medical Center. 1974 - 1975

Education

MD | SUNY Downstate Health Sciences University - College of Medicine. 1974

Research

Edward Walsh is Professor of Medicine at the University of Rochester, and former Head of Infectious Diseases at the Rochester General Hospital. His research activities since 1980 have revolved around many aspects of RSV infection. These include characterizing the function and antigenic characteristi...
Edward Walsh is Professor of Medicine at the University of Rochester, and former Head of Infectious Diseases at the Rochester General Hospital. His research activities since 1980 have revolved around many aspects of RSV infection. These include characterizing the function and antigenic characteristics of the viral proteins, primarily the F and G glycoproteins. This work also involved study of their role as potential vaccines in animal models of RSV infection. Dr. Walsh's clinical research has centered on describing the epidemiology and clinical characteristics of RSV infection in infant and adult populations with an emphasis on high risk and elderly populations. Laboratory work has described immune correlates of protection and disease pathogenesis in these groups. During the past few years the laboratory has been involved with phase 1/2/3 clinical trials of mRNA COVID vaccines and phase 1/2/3 trials of subunit preFusion RSV vaccines in adults.

Selected research publications:
Walsh EE, Hruska JF. Monoclonal antibodies to respiratory syncytial virus proteins: Identification of the fusion protein. J Virol 47:171, 1983.
Walsh EE, Hall CB, Schlesinger JJ, Brandriss, MW, Hildreth S, Paradiso P. Comparison of antigenic sites of subtype specific respiratory syncytial virus attachment proteins. J Gen Virol 70:2953, 1989.
Walsh EE, Falsey AR, Sullender WM. Monoclonal antibody neutralization escape mutants of respiratory syncytial virus with unique alterations in the attachment (G) protein. J. Gen. Virol. 69:479-487, 1998.
Falsey AR, Hennessey PA, Formica MA, Cox C, Walsh EE. Respiratory Syncytial Virus Infection in Elderly and High-Risk Adults. New Engl J Med 2005; 352:1749-1759.
Walsh EE, Peterson DR, Falsey AR. Another piece of the puzzle: Human Metapneumovirus Infection in Adults. Arch Intern Med 2009;168:2489-2496
Walsh EE, Peterson DR, Kalkanoglu A, Lee FE-H, Falsey AR. Viral Shedding and Immune Responses to Respiratory Syncytial Virus Infection in Older Adults. J Infect Dis 2013; 207:1424-32
Johnson AM, McNally BA, Ionnidis I, Flano E, Teng MN, Oomens AG, Walsh EE, Peeples ME. Respiratory Syncytial Virus uses CX3CR1 as a receptor on primary human airway epithelial cultures. (2015) PLoS Pathog 11(12):e1005318.doi:10.1371/journal.ppat1005318
Walsh EE, Frenck R, Falsey AR, et al. Safety and immunogenicity of two RNA based COIVD-19 vaccine candidates. N Engl J Med 2020;383:2439-2450
Walsh EE, perez Marc G, Zareba MA, Falsey AR, et al. Efficacy and safety of a bivalent RSV prefusion F vaccine in older adults. N Engl J Med; 2023:1465-1477

Publications

Journal Articles

Respiratory syncytial virus Prefusion F vaccine.

Falsey AR, Walsh EE

Cell.. 2023 July 20186 (15):3137-3137.e1. Epub 1900 01 01.

Real-Life Assessment of BioFire FilmArray® Pneumonia Panel in Adults Hospitalized with Respiratory Illness.

Falsey AR, Branche AR, Croft DP, Formica MA, Peasley MR, Walsh EE

The Journal of infectious diseases.. 2023 June 27 Epub 06/27/2023.

Diagnosis of Respiratory Syncytial Virus in Adults Substantially Increases When Adding Sputum, Saliva, and Serology Testing to Nasopharyngeal Swab RT-PCR.

Ramirez J, Carrico R, Wilde A, Junkins A, Furmanek S, Chandler T, Schulz P, Hubler R, Peyrani P, Liu Q, Trivedi S, Uppal S, Kalina WV, Falsey AR, Walsh EE, Yacisin K, Jodar L, Gessner BD, Begier E

Infectious diseases and therapy.. 2023 May 6 Epub 05/06/2023.

Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults.

Walsh EE, Pérez Marc G, Zareba AM, Falsey AR, Jiang Q, Patton M, Polack FP, Llapur C, Doreski PA, Ilangovan K, Rämet M, Fukushima Y, Hussen N, Bont LJ, Cardona J, DeHaan E, Castillo Villa G, Ingilizova M, Eiras D, Mikati T, Shah RN, Schneider K, Cooper D, Koury K, Lino MM, Anderson AS, Jansen KU, Swanson KA, Gurtman A, Gruber WC, Schmoele-Thoma B,

The New England journal of medicine.. 2023 April 5 Epub 04/05/2023.

Clinical impact of healthcare-associated respiratory syncytial virus in hospitalized adults.

Hill-Ricciuti A, Walsh EE, Greendyke WG, Choi Y, Barrett A, Alba L, Branche AR, Falsey AR, Phillips M, Finelli L, Saiman L

Infection control and hospital epidemiology.. 2022 November 14 :1-7. Epub 11/14/2022.

Perturbations in Respiratory Syncytial Virus (RSV) Activity During the SARS-CoV-2 Pandemic.

Falsey AR, Cameron A, Branche AR, Walsh EE

The Journal of infectious diseases.. 2022 November 1 Epub 11/01/2022.

Change in functional status associated with respiratory syncytial virus infection in hospitalized older adults.

Branche AR, Saiman L, Walsh EE, Falsey AR, Jia H, Barrett A, Alba L, Phillips M, Finelli L

Influenza and other respiratory viruses.. 2022 September 7 Epub 09/07/2022.

SARS-CoV-2 Variant Vaccine Boosters Trial: Preliminary Analyses.

Branche AR, Rouphael NG, Diemert DJ, Falsey AR, Losada C, Baden LR, Frey SE, Whitaker JA, Little SJ, Anderson EJ, Walter EB, Novak RM, Rupp R, Jackson LA, Babu TM, Kottkamp AC, Luetkemeyer AF, Immergluck LC, Presti RM, Bäcker M, Winokur PL, Mahgoub SM, Goepfert PA, Fusco DN, Malkin E, Bethony JM, Walsh EE, Graciaa DS, Samaha H, Sherman AC, Walsh SR, Abate G, Oikonomopoulou Z, El Sahly HM, Martin TCS, Rostad CA, Smith MJ, Ladner BG, Porterfield L, Dunstan M, Wald A, Davis T, Atmar RL, Mulligan MJ, Lyke KE, Posavad CM, Meagher MA, Stephens DS, Neuzil KM, Abebe K, Hill H, Albert J, Lewis TC, Giebeig LA, Eaton A, Netzl A, Wilks SH, Türeli S, Makhene M, Crandon S, Lee M, Nayak SU, Montefiori DC, Makowski M, Smith DJ, Roberts PC, Beigel JH,

medRxiv : the preprint server for health sciences.. 2022 July 15 Epub 07/15/2022.

The Challenge of Respiratory Syncytial Virus Human Challenge Studies.

Anderson LJ, Walsh EE

The New England journal of medicine.. 2022 February 17386 (7):696-697. Epub 1900 01 01.

Featured Cover.

Falsey AR, Walsh EE, Osborne RH, Vandendijck Y, Ren X, Witek J, Kang D, Chan E, Scott J, Ispas G

Influenza and other respiratory viruses.. 2022 January 16 (1):i. Epub 12/21/2021.

Addressing Medical and Social Needs to Reduce Unnecessary Health Care Utilization and Costs: A Qualitative Study.

Liss DT, Guzman A, Walsh EE, Shaunfield S, Brown T

The Journal of ambulatory care management.. 2022 45 (3):212-220. Epub 1900 01 01.

A systems genomics approach uncovers molecular associates of RSV severity.

McCall MN, Chu CY, Wang L, Benoodt L, Thakar J, Corbett A, Holden-Wiltse J, Slaunwhite C, Grier A, Gill SR, Falsey AR, Topham DJ, Caserta MT, Walsh EE, Qiu X, Mariani TJ

PLoS computational biology.. 2021 December 2817 (12):e1009617. Epub 12/28/2021.

Phase 1/2 Randomized Study of the Immunogenicity, Safety and Tolerability of an RSV Prefusion F Vaccine in Adults With Concomitant Inactivated Influenza Vaccine.

Falsey AR, Walsh EE, Scott DA, Gurtman A, Zareba A, Jansen KU, Gruber WC, Dormitzer PR, Swanson KA, Jiang Q, Gomme E, Cooper D, Schmoele-Thoma B,

The Journal of infectious diseases.. 2021 December 21 Epub 12/21/2021.

A Randomized Phase 1/2 Study of a Respiratory Syncytial Virus Prefusion F Vaccine.

Walsh EE, Falsey AR, Scott DA, Gurtman A, Zareba AM, Jansen KU, Gruber WC, Dormitzer PR, Swanson KA, Radley D, Gomme E, Cooper D, Schmoele-Thoma B,

The Journal of infectious diseases.. 2021 December 21 Epub 12/21/2021.

Graded Administration of Second Dose of Moderna and Pfizer-BioNTech COVID-19 mRNA Vaccines in Patients With Hypersensitivity to First Dose.

Tuong LC, Capucilli P, Staicu M, Ramsey A, Walsh EE, Shahzad Mustafa S

Open forum infectious diseases.. 2021 December 8 (12):ofab507. Epub 10/06/2021.

Gene Expression Risk Scores for COVID-19 Illness Severity.

Peterson DR, Baran AM, Bhattacharya S, Branche AR, Croft DP, Corbett AM, Walsh EE, Falsey AR, Mariani TJ

The Journal of infectious diseases.. 2021 November 30 Epub 11/30/2021.

Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial.

Kalil AC, Mehta AK, Patterson TF, Erdmann N, Gomez CA, Jain MK, Wolfe CR, Ruiz-Palacios GM, Kline S, Regalado Pineda J, Luetkemeyer AF, Harkins MS, Jackson PEH, Iovine NM, Tapson VF, Oh MD, Whitaker JA, Mularski RA, Paules CI, Ince D, Takasaki J, Sweeney DA, Sandkovsky U, Wyles DL, Hohmann E, Grimes KA, Grossberg R, Laguio-Vila M, Lambert AA, Lopez de Castilla D, Kim E, Larson L, Wan CR, Traenkner JJ, Ponce PO, Patterson JE, Goepfert PA, Sofarelli TA, Mocherla S, Ko ER, Ponce de Leon A, Doernberg SB, Atmar RL, Maves RC, Dangond F, Ferreira J, Green M, Makowski M, Bonnett T, Beresnev T, Ghazaryan V, Dempsey W, Nayak SU, Dodd L, Tomashek KM, Beigel JH,

The Lancet. Respiratory medicine.. 2021 October 18 Epub 10/18/2021.

Cost determinants among adults hospitalized with respiratory syncytial virus in the United States, 2017-2019.

Choi Y, Hill-Ricciuti A, Branche AR, Sieling WD, Saiman L, Walsh EE, Phillips M, Falsey AR, Finelli L

Influenza and other respiratory viruses.. 2021 October 3 Epub 10/03/2021.

Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine.

Falsey AR, Sobieszczyk ME, Hirsch I, Sproule S, Robb ML, Corey L, Neuzil KM, Hahn W, Hunt J, Mulligan MJ, McEvoy C, DeJesus E, Hassman M, Little SJ, Pahud BA, Durbin A, Pickrell P, Daar ES, Bush L, Solis J, Carr QO, Oyedele T, Buchbinder S, Cowden J, Vargas SL, Benavides AG, Call R, Keefer MC, Kirkpatrick BD, Pullman J, Tong T, Isaacs MB, Benkeser D, Janes HE, Nason MC, Green JA, Kelly EJ, Maaske J, Mueller N, Shoemaker K, Takas T, Marshall RP, Pangalos MN, Villafana T, Gonzalez-Lopez A,

The New England journal of medicine.. 2021 September 29 Epub 09/29/2021.

SARS-CoV-2 Neutralization with BNT162b2 Vaccine Dose 3.

Falsey AR, Frenck RW, Walsh EE, Kitchin N, Absalon J, Gurtman A, Lockhart S, Bailey R, Swanson KA, Xu X, Koury K, Kalina W, Cooper D, Zou J, Xie X, Xia H, Türeci Ö, Lagkadinou E, Tompkins KR, Shi PY, Jansen KU, ?ahin U, Dormitzer PR, Gruber WC

The New England journal of medicine.. 2021 September 15 Epub 09/15/2021.

Comparative assessment of reported symptoms of influenza, respiratory syncytial virus, and human metapneumovirus infection during hospitalization and post-discharge assessed by Respiratory Intensity and Impact Questionnaire.

Falsey AR, Walsh EE, Osborne RH, Vandendijck Y, Ren X, Witek J, Kang D, Chan E, Scott J, Ispas G

Influenza and other respiratory viruses.. 2021 September 2 Epub 09/02/2021.

Gene Expression Risk Scores for COVID-19 Illness Severity.

Peterson DR, Baran AM, Bhattacharya S, Branche AR, Croft DP, Corbett AM, Walsh EE, Falsey AR, Mariani TJ

bioRxiv : the preprint server for biology.. 2021 August 24 Epub 08/24/2021.

Incidence of Respiratory Syncytial Virus Infection among Hospitalized Adults, 2017-2020.

Branche AR, Saiman L, Walsh EE, Falsey AR, Sieling WD, Greendyke W, Peterson DR, Vargas CY, Phillips M, Finelli L

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2021 July 9 Epub 07/09/2021.

Emergence of the E484K Mutation in SARS-CoV-2 Lineage B.1.1.345 in Upstate New York.

Lesho E, Corey B, Lebreton F, Ong AC, Swierczewski BE, Bennett JW, Walsh EE, Mc Gann P

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2021 June 4 Epub 06/04/2021.

Early Life RSV: Can Vaccines Help Fix Societal Ills?

Caserta MT, Walsh EE

Pediatrics.. 2021 March 18 Epub 03/18/2021.

CX3CR1 Engagement by Respiratory Syncytial Virus Leads to Induction of Nucleolin and Dysregulation of Cilia-related Genes.

Anderson CS, Chirkova T, Slaunwhite CG, Qiu X, Walsh EE, Anderson LJ, Mariani TJ

Journal of virology.. 2021 March 17 Epub 03/17/2021.

Airway gene-expression classifiers for respiratory syncytial virus (RSV) disease severity in infants.

Wang L, Chu CY, McCall MN, Slaunwhite C, Holden-Wiltse J, Corbett A, Falsey AR, Topham DJ, Caserta MT, Mariani TJ, Walsh EE, Qiu X

BMC medical genomics.. 2021 February 2514 (1):57. Epub 02/25/2021.

Publisher Correction: Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults.

Mulligan MJ, Lyke KE, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Raabe V, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Tompkins KR, Walsh EE, Frenck R, Falsey AR, Dormitzer PR, Gruber WC, ?ahin U, Jansen KU

Nature.. 2021 January 19 Epub 01/19/2021.

A cluster-control approach to a coronavirus disease 2019 (COVID-19) outbreak on a stroke ward with infection control considerations for dementia and vascular units.

Lesho EP, Walsh EE, Gutowski J, Reno L, Newhart D, Yu S, Bress J, Bronstein MZ

Infection control and hospital epidemiology.. 2021 January 11 :1-7. Epub 01/11/2021.

Diagnosis of Streptococcus pneumoniae infection using circulating antibody secreting cells.

Kyu S, Ramonell RP, Kuruvilla M, Kraft CS, Wang YF, Falsey AR, Walsh EE, Daiss JL, Paulos S, Rajam G, Wu H, Velusamy S, Lee FE

PloS one.. 2021 16 (11):e0259644. Epub 11/12/2021.

Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates.

Walsh EE, Frenck RW, Falsey AR, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Mulligan MJ, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Tompkins KR, Lyke KE, Raabe V, Dormitzer PR, Jansen KU, ?ahin U, Gruber WC

The New England journal of medicine.. 2020 October 14 Epub 10/14/2020.

Temporal Dysbiosis of Infant Nasal Microbiota Relative to Respiratory Syncytial Virus Infection.

Grier A, Gill AL, Kessler HA, Corbett A, Bandyopadhyay S, Java J, Holden-Wiltse J, Falsey AR, Topham DJ, Mariani TJ, Caserta MT, Walsh EE, Gill SR

The Journal of infectious diseases.. 2020 September 14 Epub 09/14/2020.

Airway gene expression correlates of RSV disease severity and microbiome composition in infants.

Chu CY, Qiu X, McCall MN, Wang L, Corbett A, Holden-Wiltse J, Slaunwhite C, Grier A, Gill SR, Pryhuber GS, Falsey AR, Topham DJ, Caserta MT, Walsh EE, Mariani TJ

The Journal of infectious diseases.. 2020 September 14 Epub 09/14/2020.

RNA-Based COVID-19 Vaccine BNT162b2 Selected for a Pivotal Efficacy Study.

Walsh EE, Frenck R, Falsey AR, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Mulligan MJ, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Thompkins KR, Lyke KE, Raabe V, Dormitzer PR, Jansen KU, Sahin U, Gruber WC

medRxiv : the preprint server for health sciences.. 2020 August 20 Epub 08/20/2020.

Phase 1/2 study of COVID-19 RNA vaccine BNT162b1 in adults.

Mulligan MJ, Lyke KE, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Raabe V, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Tompkins KR, Walsh EE, Frenck R, Falsey AR, Dormitzer PR, Gruber WC, ?ahin U, Jansen KU

Nature.. 2020 August 12 Epub 08/12/2020.

Unbiased analysis of peripheral blood mononuclear cells reveals CD4 T cell response to RSV matrix protein.

Thakar J, Qian Y, Benoodt L, Roumanes D, Qiu X, Laniewski N, Chu C, Slaunwhite C, Wang L, Mandava A, Chang I, Falsey AR, Caserta MT, Mariani TJ, Scheuermann RH, Walsh EE, Topham DJ

Vaccine: X.. 2020 August 75 :100065. Epub 04/21/2020.

Syncope, Near Syncope, or Nonmechanical Falls as a Presenting Feature of COVID-19.

Chen T, Hanna J, Walsh EE, Falsey AR, Laguio-Vila M, Lesho E

Annals of emergency medicine.. 2020 July 76 (1):115-117. Epub 05/08/2020.

Respiratory Syncytial Virus: An Old Foe in a New Era.

Falsey AR, Walsh EE

The Journal of infectious diseases.. 2020 June 27 Epub 06/27/2020.

Evaluation of the protective potential of antibody and T cell responses elicited by a novel preventative vaccine towards respiratory syncytial virus small hydrophobic protein.

Torrey HL, Kaliaperumal V, Bramhecha Y, Weir GM, Falsey AR, Walsh EE, Langley JM, Schepens B, Saelens X, Stanford MM

Human vaccines & immunotherapeutics.. 2020 June 12 :1-11. Epub 06/12/2020.

CX3CR1 as a respiratory syncytial virus receptor in pediatric human lung.

Anderson CS, Chu CY, Wang Q, Mereness JA, Ren Y, Donlon K, Bhattacharya S, Misra RS, Walsh EE, Pryhuber GS, Mariani TJ

Pediatric research.. 2019 November 14 Epub 11/14/2019.

Microbiome-Transcriptome Interactions Related to Severity of Respiratory Syncytial Virus Infection.

Sonawane AR, Tian L, Chu CY, Qiu X, Wang L, Holden-Wiltse J, Grier A, Gill SR, Caserta MT, Falsey AR, Topham DJ, Walsh EE, Mariani TJ, Weiss ST, Silverman EK, Glass K, Liu YY

Scientific reports.. 2019 September 259 (1):13824. Epub 09/25/2019.

Hypergammaglobulinemia and Impaired Transplacental Transfer of Respiratory Syncytial Virus Antibody in Papua New Guinea.

Atwell JE, Thumar B, Formica MA, Robinson LJ, Walsh EE, King CL, Karron RA

The Pediatric infectious disease journal.. 2019 September 38 (9):e199-e202. Epub 1900 01 01.

Mutation of Respiratory Syncytial Virus G Protein's CX3C Motif Attenuates Infection in Cotton Rats and Primary Human Airway Epithelial Cells.

Ha B, Chirkova T, Boukhvalova MS, Sun HY, Walsh EE, Anderson CS, Mariani TJ, Anderson LJ

Vaccines.. 2019 July 197 (3)Epub 07/19/2019.

Aims, Study Design, and Enrollment Results From the Assessing Predictors of Infant Respiratory Syncytial Virus Effects and Severity Study.

Walsh EE, Mariani TJ, Chu C, Grier A, Gill SR, Qiu X, Wang L, Holden-Wiltse J, Corbett A, Thakar J, Benoodt L, McCall MN, Topham DJ, Falsey AR, Caserta MT

JMIR research protocols.. 2019 June 68 (6):e12907. Epub 06/06/2019.

Delayed Diagnosis of Respiratory Syncytial Virus Infections in Hospitalized Adults: Individual Patient Data, Chart Review Analysis and Physician Survey in the USA.

Lee N, Walsh EE, Sander I, Stolper R, Zakar J, Wyffels V, Myers D, Fleischhackl R

The Journal of infectious diseases.. 2019 May 9 Epub 05/09/2019.

Respiratory syncytial virus-associated illness in adults with advanced chronic obstructive pulmonary disease and/or congestive heart failure.

Falsey AR, Walsh EE, Esser MT, Shoemaker K, Yu L, Griffin MP

Journal of medical virology.. 2019 January 91 (1):65-71. Epub 09/24/2018.

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.

Mazur NI, Higgins D, Nunes MC, Melero JA, Langedijk AC, Horsley N, Buchholz UJ, Openshaw PJ, McLellan JS, Englund JA, Mejias A, Karron RA, Simões EA, Knezevic I, Ramilo O, Piedra PA, Chu HY, Falsey AR, Nair H, Kragten-Tabatabaie L, Greenough A, Baraldi E, Papadopoulos NG, Vekemans J, Polack FP, Powell M, Satav A, Walsh EE, Stein RT, Graham BS, Bont LJ,

The Lancet. Infectious diseases.. 2018 October 18 (10):e295-e311. Epub 06/18/2018.

T-Cell Responses in Adults During Natural Respiratory Syncytial Virus Infection.

Roumanes D, Falsey AR, Quataert S, Secor-Socha S, Lee FE, Yang H, Bandyopadhyay S, Holden-Wiltse J, Topham DJ, Walsh EE

The Journal of infectious diseases.. 2018 July 2218 (3):418-428. Epub 1900 01 01.

Virus-Specific Antibody, Viral Load, and Disease Severity in Respiratory Syncytial Virus Infection.

Walsh EE, Wang L, Falsey AR, Qiu X, Corbett A, Holden-Wiltse J, Mariani TJ, Topham DJ, Caserta MT

The Journal of infectious diseases.. 2018 June 20218 (2):208-217. Epub 1900 01 01.

Importation, Mitigation, and Genomic Epidemiology of Candida auris at a Large Teaching Hospital.

Lesho EP, Bronstein MZ, McGann P, Stam J, Kwak Y, Maybank R, McNamara J, Callahan M, Campbell J, Hinkle MK, Walsh EE

Infection control and hospital epidemiology.. 2018 January 39 (1):53-57. Epub 12/06/2017.

Association of Dynamic Changes in the CD4 T-Cell Transcriptome With Disease Severity During Primary Respiratory Syncytial Virus Infection in Young Infants.

Mariani TJ, Qiu X, Chu CY, Wang L, Thakar J, Holden-Wiltse J, Corbett A, Topham DJ, Falsey AR, Caserta MT, Walsh EE

The Journal of infectious diseases.. 2017 November 15216 (8):1027-1037. Epub 1900 01 01.

Identifying Gaps in Respiratory Syncytial Virus Disease Epidemiology in the United States Prior to the Introduction of Vaccines.

Kim L, Rha B, Abramson JS, Anderson LJ, Byington CL, Chen GL, DeVincenzo J, Edwards KM, Englund JA, Falsey AR, Griffin MR, Karron RA, Martin KG, Meissner HC, Munoz FM, Pavia AT, Piedra PA, Schaffner W, Simões EAF, Singleton R, Talbot HK, Walsh EE, Zucker JR, Gerber SI

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2017 September 1565 (6):1020-1025. Epub 1900 01 01.

Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness.

Bhattacharya S, Rosenberg AF, Peterson DR, Grzesik K, Baran AM, Ashton JM, Gill SR, Corbett AM, Holden-Wiltse J, Topham DJ, Walsh EE, Mariani TJ, Falsey AR

Scientific reports.. 2017 July 267 (1):6548. Epub 07/26/2017.

Can Analysis of Routine Viral Testing Provide Accurate Estimates of Respiratory Syncytial Virus Disease Burden in Adults?

Datta S, Walsh EE, Peterson DR, Falsey AR

The Journal of infectious diseases.. 2017 June 1215 (11):1706-1710. Epub 1900 01 01.

Compassionate use experience with high-titer respiratory syncytical virus (RSV) immunoglobulin in RSV-infected immunocompromised persons.

Falsey AR, Koval C, DeVincenzo JP, Walsh EE

Transplant infectious disease : an official journal of the Transplantation Society.. 2017 April 19 (2)Epub 03/06/2017.

Development of a Global Respiratory Severity Score for Respiratory Syncytial Virus Infection in Infants.

Caserta MT, Qiu X, Tesini B, Wang L, Murphy A, Corbett A, Falsey AR, Holden-Wiltse J, Walsh EE

The Journal of infectious diseases.. 2017 March 1215 (5):750-756. Epub 1900 01 01.

Respiratory Syncytial Virus Infection: An Illness for All Ages.

Walsh EE

Clinics in chest medicine.. 2017 March 38 (1):29-36. Epub 12/27/2016.

The Healthy Infant Nasal Transcriptome: A Benchmark Study.

Chu CY, Qiu X, Wang L, Bhattacharya S, Lofthus G, Corbett A, Holden-Wiltse J, Grier A, Tesini B, Gill SR, Falsey AR, Caserta MT, Walsh EE, Mariani TJ

Scientific reports.. 2016 September 236 :33994. Epub 09/23/2016.

Provider Decisions to Treat Respiratory Illnesses with Antibiotics: Insights from a Randomized Controlled Trial.

Branche AR, Walsh EE, Jadhav N, Karmally R, Baran A, Peterson DR, Falsey AR

PloS one.. 2016 11 (4):e0152986. Epub 04/04/2016.

Development of Electrochemiluminescent Serology Assays to Measure the Humoral Response to Antigens of Respiratory Syncytial Virus.

Maifeld SV, Ro B, Mok H, Chu M, Yu L, Yamagata R, Leonardson T, Chio V, Parhy B, Park S, Carlson M, Machhi S, Ulbrandt N, Falsey AR, Walsh EE, Wang CK, Esser MT, Zuo F

PloS one.. 2016 11 (4):e0153019. Epub 04/12/2016.

Serum Procalcitonin Measurement and Viral Testing to Guide Antibiotic Use for Respiratory Infections in Hospitalized Adults: A Randomized Controlled Trial.

Branche AR, Walsh EE, Vargas R, Hulbert B, Formica MA, Baran A, Peterson DR, Falsey AR

The Journal of infectious diseases.. 2015 December 1212 (11):1692-700. Epub 04/24/2015.

Effect of Preexisting Serum and Mucosal Antibody on Experimental Respiratory Syncytial Virus (RSV) Challenge and Infection of Adults.

Bagga B, Cehelsky JE, Vaishnaw A, Wilkinson T, Meyers R, Harrison LM, Roddam PL, Walsh EE, DeVincenzo JP

The Journal of infectious diseases.. 2015 December 1212 (11):1719-25. Epub 05/14/2015.

Respiratory Syncytial Virus Uses CX3CR1 as a Receptor on Primary Human Airway Epithelial Cultures.

Johnson SM, McNally BA, Ioannidis I, Flano E, Teng MN, Oomens AG, Walsh EE, Peeples ME

PLoS pathogens.. 2015 December 11 (12):e1005318. Epub 12/11/2015.

Should clinical case definitions of influenza in hospitalized older adults include fever?

Falsey AR, Baran A, Walsh EE

Influenza and other respiratory viruses.. 2015 August 9 Suppl 1 (Suppl 1):23-9. Epub 1900 01 01.

Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.

Halliley JL, Tipton CM, Liesveld J, Rosenberg AF, Darce J, Gregoretti IV, Popova L, Kaminiski D, Fucile CF, Albizua I, Kyu S, Chiang KY, Bradley KT, Burack R, Slifka M, Hammarlund E, Wu H, Zhao L, Walsh EE, Falsey AR, Randall TD, Cheung WC, Sanz I, Lee FE

Immunity.. 2015 July 2143 (1):132-45. Epub 07/14/2015.

Superiority of transcriptional profiling over procalcitonin for distinguishing bacterial from viral lower respiratory tract infections in hospitalized adults.

Suarez NM, Bunsow E, Falsey AR, Walsh EE, Mejias A, Ramilo O

The Journal of infectious diseases.. 2015 July 15212 (2):213-22. Epub 01/29/2015.

Challenges and opportunities in developing respiratory syncytial virus therapeutics.

Simões EA, DeVincenzo JP, Boeckh M, Bont L, Crowe JE, Griffiths P, Hayden FG, Hodinka RL, Smyth RL, Spencer K, Thirstrup S, Walsh EE, Whitley RJ

The Journal of infectious diseases.. 2015 March 15211 Suppl 1 :S1-S20. Epub 1900 01 01.

Respiratory syncytial virus transplacental antibody transfer and kinetics in mother-infant pairs in Bangladesh.

Chu HY, Steinhoff MC, Magaret A, Zaman K, Roy E, Langdon G, Formica MA, Walsh EE, Englund JA

The Journal of infectious diseases.. 2014 November 15210 (10):1582-9. Epub 06/05/2014.

Detection of respiratory viruses in sputum from adults by use of automated multiplex PCR.

Branche AR, Walsh EE, Formica MA, Falsey AR

Journal of clinical microbiology.. 2014 October 52 (10):3590-6. Epub 07/23/2014.

Respiratory syncytial virus in hematopoietic cell transplant recipients: factors determining progression to lower respiratory tract disease.

Kim YJ, Guthrie KA, Waghmare A, Walsh EE, Falsey AR, Kuypers J, Cent A, Englund JA, Boeckh M

The Journal of infectious diseases.. 2014 April 15209 (8):1195-204. Epub 12/23/2013.

Reply to Musher et al.

Falsey AR, Walsh EE

The Journal of infectious diseases.. 2014 February 15209 (4):633-5. Epub 11/11/2013.

Clinical impact of human coronaviruses 229E and OC43 infection in diverse adult populations.

Walsh EE, Shin JH, Falsey AR

The Journal of infectious diseases.. 2013 November 15208 (10):1634-42. Epub 08/06/2013.

Bacterial complications of respiratory tract viral illness: a comprehensive evaluation.

Falsey AR, Becker KL, Swinburne AJ, Nylen ES, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Baran A, Walsh EE

The Journal of infectious diseases.. 2013 August 1208 (3):432-41. Epub 05/09/2013.

Risk factors for respiratory syncytial virus illness among patients with chronic obstructive pulmonary disease.

Mehta J, Walsh EE, Mahadevia PJ, Falsey AR

COPD.. 2013 June 10 (3):293-9. Epub 03/28/2013.

Viral shedding and immune responses to respiratory syncytial virus infection in older adults.

Walsh EE, Peterson D, Kalkanoglu A, Lee FE, Falsey AR

The Journal of infectious diseases.. 2013 May 1207 (9):1424-32. Epub 02/04/2013.

Can serum procalcitonin levels help interpret indeterminate chest radiographs in patients hospitalized with acute respiratory illness?

Walsh EE, Swinburne AJ, Becker KL, Nylen ES, Snider RH, Baran A, Peterson DR, Falsey AR

Journal of hospital medicine.. 2013 February 8 (2):61-7. Epub 10/19/2012.

Subunit and virus-like particle vaccine approaches for respiratory syncytial virus.

Morrison TG, Walsh EE

Current topics in microbiology and immunology.. 2013 372 :285-306. Epub 1900 01 01.

Factors associated with symptomatic rhinovirus infection in patients with COPD.

Gandhi A, Walsh EE, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Baran A, Falsey AR

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2012 December 55 (4):343-7. Epub 09/19/2012.

Simple method for combining sputum and nasal samples for virus detection by reverse transcriptase PCR.

Falsey AR, Formica MA, Walsh EE

Journal of clinical microbiology.. 2012 August 50 (8):2835. Epub 06/12/2012.

Respiratory syncytial virus infection in adult populations.

Walsh EE, Falsey AR

Infectious disorders drug targets.. 2012 April 12 (2):98-102. Epub 1900 01 01.

Statins and influenza: can we move forward?

Walsh EE

The Journal of infectious diseases.. 2012 January 1205 (1):1-3. Epub 12/13/2011.

Yield of sputum for viral detection by reverse transcriptase PCR in adults hospitalized with respiratory illness.

Falsey AR, Formica MA, Walsh EE

Journal of clinical microbiology.. 2012 January 50 (1):21-4. Epub 11/16/2011.

Utility of serum procalcitonin values in patients with acute exacerbations of chronic obstructive pulmonary disease: a cautionary note.

Falsey AR, Becker KL, Swinburne AJ, Nylen ES, Snider RH, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Walsh EE

International journal of chronic obstructive pulmonary disease.. 2012 7 :127-35. Epub 02/23/2012.

The effect of steroid use in hospitalized adults with respiratory syncytial virus-related illness.

Lee FE, Walsh EE, Falsey AR

Chest.. 2011 November 140 (5):1155-1161. Epub 05/12/2011.

Respiratory syncytial virus infection in adults.

Walsh EE

Seminars in respiratory and critical care medicine.. 2011 August 32 (4):423-32. Epub 08/19/2011.

Circulating human antibody-secreting cells during vaccinations and respiratory viral infections are characterized by high specificity and lack of bystander effect.

Lee FE, Halliley JL, Walsh EE, Moscatiello AP, Kmush BL, Falsey AR, Randall TD, Kaminiski DA, Miller RK, Sanz I

The Journal of immunology : official journal of the American Association of Immunologists.. 2011 May 1186 (9):5514-21. Epub 03/25/2011.

Sustained reduction in methicillin-resistant Staphylococcus aureus wound infections after cardiothoracic surgery.

Walsh EE, Greene L, Kirshner R

Archives of internal medicine.. 2011 January 10171 (1):68-73. Epub 09/13/2010.

Circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults.

Lee FE, Falsey AR, Halliley JL, Sanz I, Walsh EE

The Journal of infectious diseases.. 2010 December 1202 (11):1659-66. Epub 10/27/2010.

Humoral response to the central unglycosylated region of the respiratory syncytial virus attachment protein.

Murata Y, Lightfoote PM, Biear JN, Falsey AR, Walsh EE

Vaccine.. 2010 August 3128 (38):6242-6. Epub 07/23/2010.

Utilization of serologic assays to support efficacy of vaccines in nonclinical and clinical trials: meeting at the crossroads.

Madore DV, Meade BD, Rubin F, Deal C, Lynn F,

Vaccine.. 2010 June 2328 (29):4539-47. Epub 05/12/2010.

Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunization.

Halliley JL, Kyu S, Kobie JJ, Walsh EE, Falsey AR, Randall TD, Treanor J, Feng C, Sanz I, Lee FE

Vaccine.. 2010 April 3028 (20):3582-7. Epub 03/16/2010.

Identification of and human serum reactogenicity to neutralizing epitopes within the central unglycosylated region of the respiratory syncytial virus attachment protein.

Murata Y, Lightfoote PM, Falsey AR, Walsh EE

Clinical and vaccine immunology : CVI.. 2010 April 17 (4):695-7. Epub 02/17/2010.

Humoral immunity to human metapneumovirus infection in adults.

Falsey AR, Hennessey PA, Formica MA, Criddle MM, Biear JM, Walsh EE

Vaccine.. 2010 February 1028 (6):1477-80. Epub 12/08/2009.

Microneutralization assay for the measurement of neutralizing antibodies to human metapneumovirus.

Falsey AR, Formica MA, Walsh EE

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2009 December 46 (4):314-7. Epub 10/08/2009.

Potent high-affinity antibodies for treatment and prophylaxis of respiratory syncytial virus derived from B cells of infected patients.

Collarini EJ, Lee FE, Foord O, Park M, Sperinde G, Wu H, Harriman WD, Carroll SF, Ellsworth SL, Anderson LJ, Tripp RA, Walsh EE, Keyt BA, Kauvar LM

The Journal of immunology : official journal of the American Association of Immunologists.. 2009 November 15183 (10):6338-45. Epub 10/19/2009.

Risk factors for respiratory failure associated with respiratory syncytial virus infection in adults.

Duncan CB, Walsh EE, Peterson DR, Lee FE, Falsey AR

The Journal of infectious diseases.. 2009 October 15200 (8):1242-6. Epub 1900 01 01.

Human metapneumovirus infections in adults: another piece of the puzzle.

Walsh EE, Peterson DR, Falsey AR

Archives of internal medicine.. 2008 December 8168 (22):2489-96. Epub 1900 01 01.

Comparison of the safety and immunogenicity of 2 respiratory syncytial virus (rsv) vaccines--nonadjuvanted vaccine or vaccine adjuvanted with alum--given concomitantly with influenza vaccine to high-risk elderly individuals.

Falsey AR, Walsh EE, Capellan J, Gravenstein S, Zambon M, Yau E, Gorse GJ, Edelman R, Hayden FG, McElhaney JE, Neuzil KM, Nichol KL, Simões EA, Wright PF, Sales VM

The Journal of infectious diseases.. 2008 November 1198 (9):1317-26. Epub 1900 01 01.

Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infection.

Lee FE, Walsh EE, Falsey AR, Lumb ME, Okam NV, Liu N, Divekar AA, Hall CB, Mosmann TR

The Journal of infectious diseases.. 2007 June 15195 (12):1779-88. Epub 05/09/2007.

Pulmonary complications of interpandemic influenza A in hospitalized adults.

Murata Y, Walsh EE, Falsey AR

The Journal of infectious diseases.. 2007 April 1195 (7):1029-37. Epub 02/15/2007.

Is clinical recognition of respiratory syncytial virus infection in hospitalized elderly and high-risk adults possible?

Walsh EE, Peterson DR, Falsey AR

The Journal of infectious diseases.. 2007 April 1195 (7):1046-51. Epub 02/15/2007.

Influenza: evolving strategies in treatment and prevention.

Lynch JP, Walsh EE

Seminars in respiratory and critical care medicine.. 2007 April 28 (2):144-58. Epub 1900 01 01.

Impact of rapid diagnosis on management of adults hospitalized with influenza.

Falsey AR, Murata Y, Walsh EE

Archives of internal medicine.. 2007 February 26167 (4):354-60. Epub 01/22/2007.

Serosurvey of human metapneumovirus infection in Croatia.

Ljubin Sternak S, Vilibi? Cavlek T, Falsey AR, Walsh EE, Mlinari? Galinovi? G

Croatian medical journal.. 2006 December 47 (6):878-81. Epub 1900 01 01.

Serum antibody decay in adults following natural respiratory syncytial virus infection.

Falsey AR, Singh HK, Walsh EE

Journal of medical virology.. 2006 November 78 (11):1493-7. Epub 1900 01 01.

Detection of respiratory syncytial virus in adults with chronic obstructive pulmonary disease.

Falsey AR, Formica MA, Hennessey PA, Criddle MM, Sullender WM, Walsh EE

American journal of respiratory and critical care medicine.. 2006 March 15173 (6):639-43. Epub 12/30/2005.

Viral pneumonia in older adults.

Falsey AR, Walsh EE

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2006 February 1542 (4):518-24. Epub 01/06/2006.

Detection of respiratory syncytial virus and human metapneumovirus by reverse transcription polymerase chain reaction in adults with and without respiratory illness.

Falsey AR, Criddle MC, Walsh EE

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2006 January 35 (1):46-50. Epub 1900 01 01.

The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects.

Lee FE, Walsh EE, Falsey AR, Liu N, Liu D, Divekar A, Snyder-Cappione JE, Mosmann TR

Mechanisms of ageing and development.. 2005 November 126 (11):1223-9. Epub 1900 01 01.

Respiratory syncytial virus infection in elderly and high-risk adults.

Falsey AR, Hennessey PA, Formica MA, Cox C, Walsh EE

The New England journal of medicine.. 2005 April 28352 (17):1749-59. Epub 1900 01 01.

Respiratory syncytial virus infection in elderly adults.

Falsey AR, Walsh EE

Drugs & aging.. 2005 22 (7):577-87. Epub 1900 01 01.

Experimental infection of humans with A2 respiratory syncytial virus.

Lee FE, Walsh EE, Falsey AR, Betts RF, Treanor JJ

Antiviral research.. 2004 September 63 (3):191-6. Epub 1900 01 01.

Humoral and mucosal immunity in protection from natural respiratory syncytial virus infection in adults.

Walsh EE, Falsey AR

The Journal of infectious diseases.. 2004 July 15190 (2):373-8. Epub 06/18/2004.

Age related differences in humoral immune response to respiratory syncytial virus infection in adults.

Walsh EE, Falsey AR

Journal of medical virology.. 2004 June 73 (2):295-9. Epub 1900 01 01.

Risk factors for severe respiratory syncytial virus infection in elderly persons.

Walsh EE, Peterson DR, Falsey AR

The Journal of infectious diseases.. 2004 January 15189 (2):233-8. Epub 01/09/2004.

Lack of sensitivity of rapid antigen tests for the diagnosis of respiratory syncytial virus infection in adults.

Casiano-Colón AE, Hulbert BB, Mayer TK, Walsh EE, Falsey AR

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2003 October 28 (2):169-74. Epub 1900 01 01.

Comparison of quantitative reverse transcription-PCR to viral culture for assessment of respiratory syncytial virus shedding.

Falsey AR, Formica MA, Treanor JJ, Walsh EE

Journal of clinical microbiology.. 2003 September 41 (9):4160-5. Epub 1900 01 01.

Novel coronavirus and severe acute respiratory syndrome.

Falsey AR, Walsh EE

Lancet.. 2003 April 19361 (9366):1312-3. Epub 1900 01 01.

Human metapneumovirus infections in young and elderly adults.

Falsey AR, Erdman D, Anderson LJ, Walsh EE

The Journal of infectious diseases.. 2003 March 1187 (5):785-90. Epub 02/24/2003.

Intermittent compression pump for nonhealing wounds in patients with limb ischemia. The Mayo Clinic experience (1998-2000).

Montori VM, Kavros SJ, Walsh EE, Rooke TW

International angiology : a journal of the International Union of Angiology.. 2002 December 21 (4):360-6. Epub 1900 01 01.

Clinical features of influenza A virus infection in older hospitalized persons.

Walsh EE, Cox C, Falsey AR

Journal of the American Geriatrics Society.. 2002 September 50 (9):1498-503. Epub 1900 01 01.

Rhinovirus and coronavirus infection-associated hospitalizations among older adults.

Falsey AR, Walsh EE, Hayden FG

The Journal of infectious diseases.. 2002 May 1185 (9):1338-41. Epub 04/16/2002.

Diagnosis of respiratory syncytial virus infection: comparison of reverse transcription-PCR to viral culture and serology in adults with respiratory illness.

Falsey AR, Formica MA, Walsh EE

Journal of clinical microbiology.. 2002 March 40 (3):817-20. Epub 1900 01 01.

Response of C-reactive protein and serum amyloid A to influenza A infection in older adults.

Falsey AR, Walsh EE, Francis CW, Looney RJ, Kolassa JE, Hall WJ, Abraham GN

The Journal of infectious diseases.. 2001 April 1183 (7):995-9. Epub 02/23/2001.

Detection of IgA and IgG but not IgE antibody to respiratory syncytial virus in nasal washes and sera from infants with wheezing.

De Alarcon A, Walsh EE, Carper HT, La Russa JB, Evans BA, Rakes GP, Platts-Mills TA, Heymann PW

The Journal of pediatrics.. 2001 March 138 (3):311-7. Epub 1900 01 01.

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.

Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, Walsh EE, Freeman MW, Golenbock DT, Anderson LJ, Finberg RW

Nature immunology.. 2000 November 1 (5):398-401. Epub 1900 01 01.

Respiratory syncytial virus infection in adults.

Falsey AR, Walsh EE

Clinical microbiology reviews.. 2000 July 13 (3):371-84. Epub 1900 01 01.

Evaluation of the live attenuated cpts 248/404 RSV vaccine in combination with a subunit RSV vaccine (PFP-2) in healthy young and older adults.

Gonzalez IM, Karron RA, Eichelberger M, Walsh EE, Delagarza VW, Bennett R, Chanock RM, Murphy BR, Clements-Mann ML, Falsey AR

Vaccine.. 2000 March 618 (17):1763-72. Epub 1900 01 01.

Comparison of respiratory syncytial virus humoral immunity and response to infection in young and elderly adults.

Falsey AR, Walsh EE, Looney RJ, Kolassa JE, Formica MA, Criddle MC, Hall WJ

Journal of medical virology.. 1999 October 59 (2):221-6. Epub 1900 01 01.

Respiratory syncytial and other virus infections in persons with chronic cardiopulmonary disease.

Walsh EE, Falsey AR, Hennessey PA

American journal of respiratory and critical care medicine.. 1999 September 160 (3):791-5. Epub 1900 01 01.

Human monoclonal antibodies isolated from spontaneous Epstein-Barr virus-transformed tumors of Hu-SPL-SCID mice and specific for fusion protein display broad neutralizing activity toward respiratory syncytial virus.

Chamat S, Walsh EE, Anderson D, Osta M, Awaraji C, Pan LZ, Ochi J, Shuey S, Brams P

The Journal of infectious diseases.. 1999 August 180 (2):268-77. Epub 1900 01 01.

A simple and reproducible method for collecting nasal secretions in frail elderly adults, for measurement of virus-specific IgA.

Walsh EE, Falsey AR

The Journal of infectious diseases.. 1999 May 179 (5):1268-73. Epub 1900 01 01.

Monoclonal antibody neutralization escape mutants of respiratory syncytial virus with unique alterations in the attachment (G) protein.

Walsh EE, Falsey AR, Sullender WM

The Journal of general virology.. 1998 March 79 ( Pt 3) :479-87. Epub 1900 01 01.

Relationship of serum antibody to risk of respiratory syncytial virus infection in elderly adults.

Falsey AR, Walsh EE

The Journal of infectious diseases.. 1998 February 177 (2):463-6. Epub 1900 01 01.

Severity of respiratory syncytial virus infection is related to virus strain.

Walsh EE, McConnochie KM, Long CE, Hall CB

The Journal of infectious diseases.. 1997 April 175 (4):814-20. Epub 1900 01 01.

Respiratory syncytial virus infection in the elderly.

Mlinaric-Galinovic G, Falsey AR, Walsh EE

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.. 1996 October 15 (10):777-81. Epub 1900 01 01.

Humoral, mucosal, and cellular immune response to topical immunization with a subunit respiratory syncytial virus vaccine.

Walsh EE

The Journal of infectious diseases.. 1994 August 170 (2):345-50. Epub 1900 01 01.

Comparison of antibody concentrations and protective activity of respiratory syncytial virus immune globulin and conventional immune globulin.

Siber GR, Leombruno D, Leszczynski J, McIver J, Bodkin D, Gonin R, Thompson CM, Walsh EE, Piedra PA, Hemming VG

The Journal of infectious diseases.. 1994 June 169 (6):1368-73. Epub 1900 01 01.

Immunogenicity of purified F glycoprotein of respiratory syncytial virus: clinical and immune responses to subsequent natural infection in children.

Belshe RB, Anderson EL, Walsh EE

The Journal of infectious diseases.. 1993 October 168 (4):1024-9. Epub 1900 01 01.

Transmission of Chlamydia pneumoniae.

Falsey AR, Walsh EE

The Journal of infectious diseases.. 1993 August 168 (2):493-6. Epub 1900 01 01.

Mucosal immunization with a subunit respiratory syncytial virus vaccine in mice.

Walsh EE

Vaccine.. 1993 11 (11):1135-8. Epub 1900 01 01.

Protective activity of a human respiratory syncytial virus immune globulin prepared from donors screened by microneutralization assay.

Siber GR, Leszcynski J, Pena-Cruz V, Ferren-Gardner C, Anderson R, Hemming VG, Walsh EE, Burns J, McIntosh K, Gonin R

The Journal of infectious diseases.. 1992 March 165 (3):456-63. Epub 1900 01 01.

Viral respiratory infections in the institutionalized elderly: clinical and epidemiologic findings.

Falsey AR, Treanor JJ, Betts RF, Walsh EE

Journal of the American Geriatrics Society.. 1992 February 40 (2):115-9. Epub 1900 01 01.

Humoral immunity to respiratory syncytial virus infection in the elderly.

Falsey AR, Walsh EE

Journal of medical virology.. 1992 January 36 (1):39-43. Epub 1900 01 01.

Group-specific serum antibody responses in children with primary and recurrent respiratory syncytial virus infections.

Muelenaer PM, Henderson FW, Hemming VG, Walsh EE, Anderson LJ, Prince GA, Murphy BR

The Journal of infectious diseases.. 1991 July 164 (1):15-21. Epub 1900 01 01.

Immunity to and frequency of reinfection with respiratory syncytial virus.

Hall CB, Walsh EE, Long CE, Schnabel KC

The Journal of infectious diseases.. 1991 April 163 (4):693-8. Epub 1900 01 01.

Interleukin-1-inhibitor activity induced by respiratory syncytial virus: abrogation of virus-specific and alternate human lymphocyte proliferative responses.

Salkind AR, McCarthy DO, Nichols JE, Domurat FM, Walsh EE, Roberts NJ

The Journal of infectious diseases.. 1991 January 163 (1):71-7. Epub 1900 01 01.

Occurrence of groups A and B of respiratory syncytial virus over 15 years: associated epidemiologic and clinical characteristics in hospitalized and ambulatory children.

Hall CB, Walsh EE, Schnabel KC, Long CE, McConnochie KM, Hildreth SW, Anderson LJ

The Journal of infectious diseases.. 1990 December 162 (6):1283-90. Epub 1900 01 01.

Serologic evidence of respiratory syncytial virus infection in nursing home patients.

Falsey AR, Walsh EE, Betts RF

The Journal of infectious diseases.. 1990 August 162 (2):568-9. Epub 1900 01 01.

Variation in severity of respiratory syncytial virus infections with subtype.

McConnochie KM, Hall CB, Walsh EE, Roghmann KJ

The Journal of pediatrics.. 1990 July 117 (1 Pt 1):52-62. Epub 1900 01 01.

Immunogenicity of a purified fragment of 17D yellow fever envelope protein.

Brandriss MW, Schlesinger JJ, Walsh EE

The Journal of infectious diseases.. 1990 June 161 (6):1134-9. Epub 1900 01 01.

Cell surface expression of yellow fever virus non-structural glycoprotein NS1: consequences of interaction with antibody.

Schlesinger JJ, Brandriss MW, Putnak JR, Walsh EE

The Journal of general virology.. 1990 March 71 ( Pt 3) :593-9. Epub 1900 01 01.

Comparison of antigenic sites of subtype-specific respiratory syncytial virus attachment proteins.

Walsh EE, Hall CB, Schlesinger JJ, Brandriss MW, Hildreth S, Paradiso P

The Journal of general virology.. 1989 November 70 ( Pt 11) :2953-61. Epub 1900 01 01.

Serum immunoglobulin G antibody subclass response to respiratory syncytial virus F and G glycoproteins after first, second, and third infections.

Wagner DK, Muelenaer P, Henderson FW, Snyder MH, Reimer CB, Walsh EE, Anderson LJ, Nelson DL, Murphy BR

Journal of clinical microbiology.. 1989 March 27 (3):589-92. Epub 1900 01 01.

Strain-specific serum antibody responses in infants undergoing primary infection with respiratory syncytial virus.

Hendry RM, Burns JC, Walsh EE, Graham BS, Wright PF, Hemming VG, Rodriguez WJ, Kim HW, Prince GA, McIntosh K

The Journal of infectious diseases.. 1988 April 157 (4):640-7. Epub 1900 01 01.

Antigenic relatedness between glycoproteins of human respiratory syncytial virus subgroups A and B: evaluation of the contributions of F and G glycoproteins to immunity.

Johnson PR, Olmsted RA, Prince GA, Murphy BR, Alling DW, Walsh EE, Collins PL

Journal of virology.. 1987 October 61 (10):3163-6. Epub 1900 01 01.

Immunological differences between the envelope glycoproteins of two strains of human respiratory syncytial virus.

Walsh EE, Brandriss MW, Schlesinger JJ

The Journal of general virology.. 1987 August 68 ( Pt 8) :2169-76. Epub 1900 01 01.

Immunization with glycoprotein subunits of respiratory syncytial virus to protect cotton rats against viral infection.

Walsh EE, Hall CB, Briselli M, Brandriss MW, Schlesinger JJ

The Journal of infectious diseases.. 1987 June 155 (6):1198-204. Epub 1900 01 01.

Differential immunoglobulin G subclass antibody titers to respiratory syncytial virus F and G glycoproteins in adults.

Wagner DK, Nelson DL, Walsh EE, Reimer CB, Henderson FW, Murphy BR

Journal of clinical microbiology.. 1987 April 25 (4):748-50. Epub 1900 01 01.

Protection of mice against dengue 2 virus encephalitis by immunization with the dengue 2 virus non-structural glycoprotein NS1.

Schlesinger JJ, Brandriss MW, Walsh EE

The Journal of general virology.. 1987 March 68 ( Pt 3) :853-7. Epub 1900 01 01.

Macrophages are required for influenza virus infection of human lymphocytes.

Mock DJ, Domurat F, Roberts NJ, Walsh EE, Licht MR, Keng P

The Journal of clinical investigation.. 1987 February 79 (2):620-4. Epub 1900 01 01.

Relation of serum antibody to glycoproteins of respiratory syncytial virus with immunity to infection in children.

Kasel JA, Walsh EE, Frank AL, Baxter BD, Taber LH, Glezen WP

Viral immunology.. 1987 1 (3):199-205. Epub 1900 01 01.

Effect of age and preexisting antibody on serum antibody response of infants and children to the F and G glycoproteins during respiratory syncytial virus infection.

Murphy BR, Alling DW, Snyder MH, Walsh EE, Prince GA, Chanock RM, Hemming VG, Rodriguez WJ, Kim HW, Graham BS

Journal of clinical microbiology.. 1986 November 24 (5):894-8. Epub 1900 01 01.

Dissociation between serum neutralizing and glycoprotein antibody responses of infants and children who received inactivated respiratory syncytial virus vaccine.

Murphy BR, Prince GA, Walsh EE, Kim HW, Parrott RH, Hemming VG, Rodriguez WJ, Chanock RM

Journal of clinical microbiology.. 1986 August 24 (2):197-202. Epub 1900 01 01.

Serum immunoglobulin G antibody subclass responses to respiratory syncytial virus F and G glycoproteins after primary infection.

Wagner DK, Graham BS, Wright PF, Walsh EE, Kim HW, Reimer CB, Nelson DL, Chanock RM, Murphy BR

Journal of clinical microbiology.. 1986 August 24 (2):304-6. Epub 1900 01 01.

Serum and nasal-wash immunoglobulin G and A antibody response of infants and children to respiratory syncytial virus F and G glycoproteins following primary infection.

Murphy BR, Graham BS, Prince GA, Walsh EE, Chanock RM, Karzon DT, Wright PF

Journal of clinical microbiology.. 1986 June 23 (6):1009-14. Epub 1900 01 01.

Analysis of the respiratory syncytial virus fusion protein using monoclonal and polyclonal antibodies.

Walsh EE, Cote PJ, Fernie BF, Schlesinger JJ, Brandriss MW

The Journal of general virology.. 1986 March 67 ( Pt 3) :505-13. Epub 1900 01 01.

Enhancement of respiratory syncytial virus pulmonary pathology in cotton rats by prior intramuscular inoculation of formalin-inactiva ted virus.

Prince GA, Jenson AB, Hemming VG, Murphy BR, Walsh EE, Horswood RL, Chanock RM

Journal of virology.. 1986 March 57 (3):721-8. Epub 1900 01 01.

Lethal 17D yellow fever encephalitis in mice. I. Passive protection by monoclonal antibodies to the envelope proteins of 17D yellow fever and dengue 2 viruses.

Brandriss MW, Schlesinger JJ, Walsh EE, Briselli M

The Journal of general virology.. 1986 February 67 ( Pt 2) :229-34. Epub 1900 01 01.

Respiratory syncytial virus infection of human mononuclear leukocytes in vitro and in vivo.

Domurat F, Roberts NJ, Walsh EE, Dagan R

The Journal of infectious diseases.. 1985 November 152 (5):895-902. Epub 1900 01 01.

Studies of passive immunotherapy for infections of respiratory syncytial virus in the respiratory tract of a primate model.

Hemming VG, Prince GA, Horswood RL, London WJ, Murphy BR, Walsh EE, Fischer GW, Weisman LE, Baron PA, Chanock RM

The Journal of infectious diseases.. 1985 November 152 (5):1083-7. Epub 1900 01 01.

Protection against 17D yellow fever encephalitis in mice by passive transfer of monoclonal antibodies to the nonstructural glycoprotein gp48 and by active immunization with gp48.

Schlesinger JJ, Brandriss MW, Walsh EE

The Journal of immunology : official journal of the American Association of Immunologists.. 1985 October 135 (4):2805-9. Epub 1900 01 01.

Purification and characterization of the respiratory syncytial virus fusion protein.

Walsh EE, Brandriss MW, Schlesinger JJ

The Journal of general virology.. 1985 March 66 ( Pt 3) :409-15. Epub 1900 01 01.

Analysis of 17D yellow fever virus envelope protein epitopes using monoclonal antibodies.

Schlesinger JJ, Walsh EE, Brandriss MW

The Journal of general virology.. 1984 October 65 ( Pt 10) :1637-44. Epub 1900 01 01.

Purification and characterization of GP90, one of the envelope glycoproteins of respiratory syncytial virus.

Walsh EE, Schlesinger JJ, Brandriss MW

The Journal of general virology.. 1984 April 65 ( Pt 4) :761-7. Epub 1900 01 01.

Protection from respiratory syncytial virus infection in cotton rats by passive transfer of monoclonal antibodies.

Walsh EE, Schlesinger JJ, Brandriss MW

Infection and immunity.. 1984 February 43 (2):756-8. Epub 1900 01 01.

Monoclonal antibodies to respiratory syncytial virus proteins: identification of the fusion protein.

Walsh EE, Hruska J

Journal of virology.. 1983 July 47 (1):171-7. Epub 1900 01 01.

Aerosolized ribavirin treatment of infants with respiratory syncytial viral infection. A randomized double-blind study.

Hall CB, McBride JT, Walsh EE, Bell DM, Gala CL, Hildreth S, Ten Eyck LG, Hall WJ

The New England journal of medicine.. 1983 June 16308 (24):1443-7. Epub 1900 01 01.

Rapid detection of respiratory syncytial virus with a monoclonal antibody.

Bell DM, Walsh EE, Hruska JF, Schnabel KC, Hall CB

Journal of clinical microbiology.. 1983 June 17 (6):1099-101. Epub 1900 01 01.

Ribavirin treatment of experimental respiratory syncytial viral infection. A controlled double-blind study in young adults.

Hall CB, Walsh EE, Hruska JF, Betts RF, Hall WJ

JAMA.. 1983 May 20249 (19):2666-70. Epub 1900 01 01.

Identification of the virus-specific proteins of respiratory syncytial virus temperature-sensitive mutants by immunoprecipitation.

Walsh EE, Hruska JF

Proceedings of the Society for Experimental Biology and Medicine.. 1983 February 172 (2):202-6. Epub 1900 01 01.