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Robert H. Dworkin, Ph.D.

Robert H. Dworkin, Ph.D.

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About Me

1. Director, Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks and Pediatric Anesthesia Safety Initiative (ACTTION/PASI) public-private partnership with the FDA [www.acttion.org]
2. Adjunct Senior Scientist, Department of Anesthesiology, Cr...
1. Director, Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks and Pediatric Anesthesia Safety Initiative (ACTTION/PASI) public-private partnership with the FDA [www.acttion.org]
2. Adjunct Senior Scientist, Department of Anesthesiology, Critical Care & Pain Management,
Hospital for Special Surgery Research Institute, New York, NY
3. Current funding:
- FDA, U01FD007702 (9/20/22-8/31/27): Analgesic, anesthetic, and addiction clinical trial translations, innovations, opportunities, and networks and pediatric anesthesia safety initiative (ACTTION/PASI) (PD/PI)
4. Associate Editor: Pain; Editorial Boards: Canadian Journal of Pain, Journal of Pain
5. Google Scholar: h-index = 107; total citations > 60,000

Faculty Appointments

Professor - Department of Anesthesiology and Perioperative Medicine, Research (SMD)

Professor - Department of Neurology (SMD) - Joint

Credentials

Education

PhD | Harvard University. Psychology. 1977

BA | University of Pennsylvania. Psychology, Sociology. 1971

Awards

John D. Loeser Prize for Distinguished Lifetime Achievement in the Clinical Science of Pain. 2020

Founders Award. 2018

Raymond W. Houde Award. 2018

Mitchell B. Max Award for Neuropathic Pain. 2015

John and Emma Bonica Public Service Award. 2014

John J. Bonica Award. 2011

Frontiers in Pain Lecture. 2008

Advisory Committee Service Award. 2007

Gunn-Loke Lecture, University of Washington. 2007

Wilbert Fordyce Clinical Investigator Award. 2005

Research

My major research interests are (1) methodologic aspects of analgesic clinical trials and (2) treatment and prevention of chronic and acute neuropathic and musculoskeletal pain. The primary focus of my current research involves the identification of factors that increase the assay sensitivity of ran...
My major research interests are (1) methodologic aspects of analgesic clinical trials and (2) treatment and prevention of chronic and acute neuropathic and musculoskeletal pain. The primary focus of my current research involves the identification of factors that increase the assay sensitivity of randomized clinical trials to detect differences between an efficacious treatment and a placebo control or comparison intervention. In ongoing studies, we are evaluating research designs and methods, clinical outcome assessments, statistical analyses, and benefit-risk evaluations used in randomized clinical trials and in studies with real-world data. This research and other efforts to improve the efficiency and informativeness of clinical trials of analgesic, anesthetic, and addiction interventions are being conducted under the auspices of the ACTTION/PASI public-private partnership with the FDA, of which I serve as Director.

I have also been very interested in identifying risk factors for the transition from acute to chronic pain and in evaluating interventions that have the potential to prevent chronic pain. One of our major results has been that patients with greater acute pain are more likely to develop chronic pain. This suggests that attenuating acute pain might prevent the development of chronic pain, and designing and conducting studies to test this hypothesis has been another focus of my efforts.

Finally, for the past several years I have been very interested in the design of randomized clinical trials of "classic psychedelics," including psilocybin and LSD. Psychedelics have shown promise in the treatment of various psychiatric disorders and chronic pain conditions; given the modest efficacy and problematic tolerability of existing treatments, psychedelics have the potential to improve the well-being of large numbers of patients around the world if clinical trials confirm their efficacy and safety

Publications

Journal Articles

Use of patient-reported global assessment measures in clinical trials of chronic pain treatments: ACTTION systematic review and considerations.

Langford DJ, Mark RP, France FO, Nishtar M, Park M, Sharma S, Shklyar IC, Schnitzer TJ, Conaghan PG, Amtmann D, Reeve BB, Turk DC, Dworkin RH, Gewandter JS

Pain.. 2024 November 1165 (11):2445-2454. Epub 05/14/2024.

Methods for pragmatic randomized clinical trials of pain therapies: IMMPACT statement.

Hohenschurz-Schmidt D, Cherkin D, Rice ASC, Dworkin RH, Turk DC, McDermott MP, Bair MJ, DeBar LL, Edwards RR, Evans SR, Farrar JT, Kerns RD, Rowbotham MC, Wasan AD, Cowan P, Ferguson M, Freeman R, Gewandter JS, Gilron I, Grol-Prokopczyk H, Iyengar S, Kamp C, Karp BI, Kleykamp BA, Loeser JD, Mackey S, Malamut R, McNicol E, Patel KV, Schmader K, Simon L, Steiner DJ, Veasley C, Vollert J

Pain.. 2024 October 1165 (10):2165-2183. Epub 05/03/2024.

A randomized, placebo-controlled trial of long-acting dexamethasone viscous gel delivered by transforaminal injection for lumbosacral radicular pain.

Miller A, Candido KD, Knezevic NN, Rivera J, Lunseth P, Levinson DJ, Formoso F, Solanki D, Tavel E, Krull A, Radnovich R, Burkhead D, Souza D, Helm S, Katz N, Dworkin RH, Cohen SP, Rathmell JP, Buvanendran A, Levin J, Stannard E, Ambrose C, Jaros M, Vought K, Lissin D

Pain.. 2024 June 14 Epub 06/14/2024.

Evaluating the balance of benefits and harms in chronic pain clinical trials: prioritizing individual participants over individual outcomes.

Nishtar M, Mark R, Langford DJ, McDermott MP, Markman JD, Evans SR, France FO, Park M, Sharma S, Turk DC, Dworkin RH, Gewandter JS

Regional anesthesia and pain medicine.. 2024 May 749 (5):363-367. Epub 05/07/2024.

Patient engagement in designing, conducting, and disseminating clinical pain research: IMMPACT recommended considerations.

Haroutounian S, Holzer KJ, Kerns RD, Veasley C, Dworkin RH, Turk DC, Carman KL, Chambers CT, Cowan P, Edwards RR, Eisenach JC, Farrar JT, Ferguson M, Forsythe LP, Freeman R, Gewandter JS, Gilron I, Goertz C, Grol-Prokopczyk H, Iyengar S, Jordan I, Kamp C, Kleykamp BA, Knowles RL, Langford DJ, Mackey S, Malamut R, Markman J, Martin KR, McNicol E, Patel KV, Rice ASC, Rowbotham M, Sandbrink F, Simon LS, Steiner DJ, Vollert J

Pain.. 2024 May 1165 (5):1013-1028. Epub 12/19/2023.

Sedation Research in Critically Ill Pediatric Patients: Proposals for Future Study Design From the Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research IV Workshop.

Jackson SS, Lee JJ, Jackson WM, Price JC, Beers SR, Berkenbosch JW, Biagas KV, Dworkin RH, Houck CS, Li G, Smith HAB, Ward DS, Zimmerman KO, Curley MAQ, Horvat CM, Huang DT, Pinto NP, Salorio CF, Slater R, Slomine BS, West LL, Wypij D, Yeates KO, Sun LS

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.. 2024 April 125 (4):e193-e204. Epub 12/07/2023.

Reply to "Capturing Synergy Holistically in Psychedelic Clinical Trials".

Dworkin RH, McDermott MP, Nayak SM, Strain EC

Clinical pharmacology and therapeutics.. 2024 March 115 (3):401-402. Epub 01/02/2024.

Virtual focus groups among individuals with use disorders: assessing feasibility and acceptability in an underserved clinical population.

Bergeria CL, Park B, Satyavolu PU, Dunn KE, Dworkin RH, Strain EC

Frontiers in psychiatry.. 2024 15 :1352300. Epub 03/11/2024.

Psychedelics and Psychotherapy: Is the Whole Greater than the Sum of its Parts?

Dworkin RH, McDermott MP, Nayak SM, Strain EC

Clinical pharmacology and therapeutics.. 2023 December 114 (6):1166-1169. Epub 10/05/2023.

A randomized, double-blind, placebo-controlled study of histone deacetylase type 6 inhibition for the treatment of painful diabetic peripheral neuropathy.

Michelson D, Chin WW, Dworkin RH, Freeman R, Herrmann DN, Mazitschek R, Pop-Busui R, Shaibani A, Vornov J, Jones M, Jarpe M, Hader B, Viera T, Hylan M, Kachmar T, Jones S

Pain reports.. 2023 December 8 (6):e1114. Epub 10/26/2023.

Meaningful within-patient change for clinical outcome assessments: model-based approach versus cumulative distribution functions.

Ren J, Bushmakin AG, Cislo PR, Abraham L, Cappelleri JC, Dworkin RH, Farrar JT

Journal of biopharmaceutical statistics.. 2023 November 20 :1-13. Epub 11/20/2023.

Functional imaging studies of acute administration of classic psychedelics, ketamine, and MDMA: Methodological limitations and convergent results.

Linguiti S, Vogel JW, Sydnor VJ, Pines A, Wellman N, Basbaum A, Eickhoff CR, Eickhoff SB, Edwards RR, Larsen B, McKinstry-Wu A, Scott JC, Roalf DR, Sharma V, Strain EC, Corder G, Dworkin RH, Satterthwaite TD

Neuroscience and biobehavioral reviews.. 2023 November 154 :105421. Epub 10/05/2023.

What should be the entry pain intensity criteria for chronic pain clinical trials? An IMMPACT update.

Langford DJ, Baron R, Edwards RR, Gewandter JS, Gilron I, Griffin R, Kamerman PR, Katz NP, McDermott MP, Rice ASC, Turk DC, Vollert J, Dworkin RH

Pain.. 2023 September 1164 (9):1927-1930. Epub 06/07/2023.

Covariate Adjustment in Chronic Pain Trials: An Oft-Missed Opportunity.

Langford DJ, Sharma S, McDermott MP, Beeram A, Besherat S, France FO, Mark R, Park M, Nishtar M, Turk DC, Dworkin RH, Gewandter JS

The journal of pain.. 2023 September 24 (9):1555-1569. Epub 06/14/2023.

Are psychedelic medicines the reset for chronic pain? Preliminary findings and research needs.

Zia FZ, Baumann MH, Belouin SJ, Dworkin RH, Ghauri MH, Hendricks PS, Henningfield JE, Lanier RK, Ross S, Berger A

Neuropharmacology.. 2023 August 1233 :109528. Epub 04/02/2023.

Research objectives and general considerations for pragmatic clinical trials of pain treatments: IMMPACT statement.

Hohenschurz-Schmidt DJ, Cherkin D, Rice ASC, Dworkin RH, Turk DC, McDermott MP, Bair MJ, DeBar LL, Edwards RR, Farrar JT, Kerns RD, Markman JD, Rowbotham MC, Sherman KJ, Wasan AD, Cowan P, Desjardins P, Ferguson M, Freeman R, Gewandter JS, Gilron I, Grol-Prokopczyk H, Hertz SH, Iyengar S, Kamp C, Karp BI, Kleykamp BA, Loeser JD, Mackey S, Malamut R, McNicol E, Patel KV, Sandbrink F, Schmader K, Simon L, Steiner DJ, Veasley C, Vollert J

Pain.. 2023 July 1164 (7):1457-1472. Epub 03/22/2023.

Control Conditions in Randomized Trials of Psychedelics: An ACTTION Systematic Review.

Nayak SM, Bradley MK, Kleykamp BA, Strain EC, Dworkin RH, Johnson MW

The Journal of clinical psychiatry.. 2023 May 1084 (3)Epub 05/10/2023.

Efficacy and safety of vixotrigine in idiopathic or diabetes-associated painful small fibre neuropathy (CONVEY): a phase 2 placebo-controlled enriched-enrolment randomised withdrawal study.

Faber CG, Attal N, Lauria G, Dworkin RH, Freeman R, Dawson KT, Finnigan H, Hajihosseini A, Naik H, Serenko M, Morris CJ, Kotecha M

EClinicalMedicine.. 2023 May 59 :101971. Epub 04/27/2023.

Examining the Relationships Among Treatment, Pain, and Physical Function in Patients With Osteoarthritis: A Mediation-Modeling Approach.

Abraham L, Dworkin RH, Turk DC, Markman JD, Williams DA, Bushmakin AG, Hall JA, Semel DC, Cappelleri JC, Yang R

The Clinical journal of pain.. 2023 April 139 (4):159-165. Epub 04/01/2023.

Expectations for Improvement: A Neglected but Potentially Important Covariate or Moderator for Chronic Pain Clinical Trials.

Langford DJ, Lou R, Sheen S, Amtmann D, Colloca L, Edwards RR, Farrar JT, Katz NP, McDermott MP, Reeve BB, Wasan AD, Turk DC, Dworkin RH, Gewandter JS

The journal of pain.. 2023 April 24 (4):575-581. Epub 12/26/2022.

Predicting Treatment Responses in Patients With Osteoarthritis: Results From Two Phase III Tanezumab Randomized Clinical Trials.

Colloca L, Dworkin RH, Farrar JT, Tive L, Yang J, Viktrup L, Dasic G, West CR, Whalen E, Brown MT, Gilbert SA, Verburg KM

Clinical pharmacology and therapeutics.. 2023 April 113 (4):878-886. Epub 01/31/2023.

Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations.

Edwards RR, Schreiber KL, Dworkin RH, Turk DC, Baron R, Freeman R, Jensen TS, Latremoliere A, Markman JD, Rice ASC, Rowbotham M, Staud R, Tate S, Woolf CJ, Andrews NA, Carr DB, Colloca L, Cosma-Roman D, Cowan P, Diatchenko L, Farrar J, Gewandter JS, Gilron I, Kerns RD, Marchand S, Niebler G, Patel KV, Simon LS, Tockarshewsky T, Vanhove GF, Vardeh D, Walco GA, Wasan AD, Wesselmann U

The journal of pain.. 2023 February 24 (2):204-225. Epub 10/02/2022.

Structural imaging studies of patients with chronic pain: an anatomical likelihood estimate meta-analysis.

Henn AT, Larsen B, Frahm L, Xu A, Adebimpe A, Scott JC, Linguiti S, Sharma V, Basbaum AI, Corder G, Dworkin RH, Edwards RR, Woolf CJ, Habel U, Eickhoff SB, Eickhoff CR, Wagels L, Satterthwaite TD

Pain.. 2023 January 1164 (1):e10-e24. Epub 05/13/2022.

Clinical Trial Design Challenges and Opportunities for Emerging Treatments for Opioid Use Disorder: A Review.

Kiluk BD, Kleykamp BA, Comer SD, Griffiths RR, Huhn AS, Johnson MW, Kampman KM, Pravetoni M, Preston KL, Vandrey R, Bergeria CL, Bogenschutz MP, Brown RT, Dunn KE, Dworkin RH, Finan PH, Hendricks PS, Houtsmuller EJ, Kosten TR, Lee DC, Levin FR, McRae-Clark A, Raison CL, Rasmussen K, Turk DC, Weiss RD, Strain EC

JAMA psychiatry.. 2023 January 180 (1):84-92. Epub 1900 01 01.

Perspectives on Participation in Clinical Trials Among Individuals With Pain, Depression, and/or Anxiety: An ACTTION Scoping Review.

Ferguson MC, McNicol E, Kleykamp BA, Sandoval K, Haroutounian S, Holzer KJ, Kerns RD, Veasley C, Turk DC, Dworkin RH

The journal of pain.. 2023 January 24 (1):24-37. Epub 09/22/2022.

Real-world data and evidence in pain research: a qualitative systematic review of methods in current practice.

Vollert J, Kleykamp BA, Farrar JT, Gilron I, Hohenschurz-Schmidt D, Kerns RD, Mackey S, Markman JD, McDermott MP, Rice ASC, Turk DC, Wasan AD, Dworkin RH

Pain reports.. 2023 8 (2):e1057. Epub 02/01/2023.

Initial Content Validation and Roadmap for a New Patient-Reported Outcome Measure of Pain Intensity.

Langford DJ, Gewandter JS, Amtmann D, Reeve BB, Corneli A, McKenna K, Swezey T, McFatrich M, Jensen MP, Turk DC, Dworkin RH

The journal of pain.. 2022 November 23 (11):1945-1957. Epub 07/19/2022.

Partnering with patients in clinical trials of pain treatments: a narrative review.

Holzer KJ, Veasley C, Kerns RD, Edwards RR, Gewandter JS, Langford DJ, Yaeger LH, McNicol E, Ferguson M, Turk DC, Dworkin RH, Haroutounian S

Pain.. 2022 October 1163 (10):1862-1873. Epub 01/28/2022.

If the Doors of Perception Were Cleansed, Would Chronic Pain be Relieved? Evaluating the Benefits and Risks of Psychedelics.

Dworkin RH, Anderson BT, Andrews N, Edwards RR, Grob CS, Ross S, Satterthwaite TD, Strain EC

The journal of pain.. 2022 October 23 (10):1666-1679. Epub 05/25/2022.

Clinical Trials in Pancreatitis: Opportunities and Challenges in the Design and Conduct of Patient-Focused Clinical Trials in Recurrent Acute and Chronic Pancreatitis: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.

Hart PA, Andersen DK, Lyons E, Cote GA, Cruz-Monserrate Z, Dworkin RH, Elmunzer BJ, Fogel EL, Forsmark CE, Gilron I, Golden M, Gozu A, McNair L, Pandol SJ, Perito ER, Phillips AE, Rabbitts JA, Whitcomb DC, Windsor JA, Yadav D, Palermo TM

Pancreas.. 2022 August 151 (7):715-722. Epub 1900 01 01.

A comparison of registered and published primary outcomes in clinical trials of opioid use disorder: ACTTION review and recommendations.

Kleykamp BA, Ferguson MC, McNicol E, Bixho I, Matthews M, Turk DC, Dworkin RH, Strain EC

Drug and alcohol dependence.. 2022 July 1236 :109447. Epub 04/07/2022.

Patient-Reported Chronic Pain Intensity: More Than Meets the Eye.

Langford DJ, Gewandter JS, Amtmann D, Reeve BB, Hertz S, Loeser JD, Veasley C, Turk DC, Dworkin RH

The patient.. 2022 July 15 (4):383-387. Epub 06/09/2022.

Benefit-risk assessment and reporting in clinical trials of chronic pain treatments: IMMPACT recommendations.

Kleykamp BA, Dworkin RH, Turk DC, Bhagwagar Z, Cowan P, Eccleston C, Ellenberg SS, Evans SR, Gewandter JS, Goli V, Farrar JT, Freeman RL, Garrison LP, Iyengar S, Jadad AR, Jensen MP, Junor R, Katz NP, Kesslak JP, Kopecky EA, Lissin D, Markman JD, McDermott MP, Mease PJ, O'Connor AB, Patel KV, Raja SN, Rowbotham MC, Sampaio C, Singh JA, Steigerwald I, Strand V, Tive LA, Tobias J, Wasan AD, Wilson HD

Pain.. 2022 June 1163 (6):1006-1018. Epub 09/09/2021.

WOMAC Meaningful Within-patient Change: Results From 3 Studies of Tanezumab in Patients With Moderate-to-severe Osteoarthritis of the Hip or Knee.

Conaghan PG, Dworkin RH, Schnitzer TJ, Berenbaum F, Bushmakin AG, Cappelleri JC, Viktrup L, Abraham L

The Journal of rheumatology.. 2022 June 49 (6):615-621. Epub 03/01/2022.

The prevalence of comorbid chronic pain conditions among patients with temporomandibular disorders: A systematic review.

Kleykamp BA, Ferguson MC, McNicol E, Bixho I, Arnold LM, Edwards RR, Fillingim R, Grol-Prokopczyk H, Ohrbach R, Turk DC, Dworkin RH

The Journal of the American Dental Association.. 2022 March 153 (3):241-250.e10. Epub 12/21/2021.

Pragmatic trials of pain therapies: a systematic review of methods.

Hohenschurz-Schmidt D, Kleykamp BA, Draper-Rodi J, Vollert J, Chan J, Ferguson M, McNicol E, Phalip J, Evans SR, Turk DC, Dworkin RH, Rice ASC

Pain.. 2022 January 1163 (1):21-46. Epub 1900 01 01.

Moderate to Severe Chronic Pain in Later Life: Risk and Resilience Factors for Recovery.

Li R, Dworkin RH, Chapman BP, Becerra AZ, Yang L, Mooney CJ, Seplaki CL

The journal of pain.. 2021 December 22 (12):1657-1671. Epub 06/23/2021.

Single and Composite Endpoints of Within-Patient Improvement in Symptoms: Pooled Tanezumab Data in Patients with Osteoarthritis.

Schnitzer TJ, Berenbaum F, Conaghan PG, Dworkin RH, Gatti D, Yang R, Viktrup L, Davignon I, West CR, Verburg KM

Rheumatology and therapy.. 2021 December 8 (4):1759-1774. Epub 10/04/2021.

Research approaches for evaluating opioid sparing in clinical trials of acute and chronic pain treatments: Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials recommendations.

Gewandter JS, Smith SM, Dworkin RH, Turk DC, Gan TJ, Gilron I, Hertz S, Katz NP, Markman JD, Raja SN, Rowbotham MC, Stacey BR, Strain EC, Ward DS, Farrar JT, Kroenke K, Rathmell JP, Rauck R, Brown C, Cowan P, Edwards RR, Eisenach JC, Ferguson M, Freeman R, Gray R, Giblin K, Grol-Prokopczyk H, Haythornthwaite J, Jamison RN, Martel M, McNicol E, Oshinsky M, Sandbrink F, Scholz J, Scranton R, Simon LS, Steiner D, Verburg K, Wasan AD, Wentworth K

Pain.. 2021 November 1162 (11):2669-2681. Epub 1900 01 01.

Efficacy and safety of EMA401 in peripheral neuropathic pain: results of 2 randomised, double-blind, phase 2 studies in patients with postherpetic neuralgia and painful diabetic neuropathy.

Rice ASC, Dworkin RH, Finnerup NB, Attal N, Anand P, Freeman R, Piaia A, Callegari F, Doerr C, Mondal S, Narayanan N, Ecochard L, Flossbach Y, Pandhi S

Pain.. 2021 October 1162 (10):2578-2589. Epub 1900 01 01.

Design of Clinical Trials Evaluating Sedation in Critically Ill Adults Undergoing Mechanical Ventilation: Recommendations From Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research (SCEPTER) Recommendation III.

Ward DS, Absalom AR, Aitken LM, Balas MC, Brown DL, Burry L, Colantuoni E, Coursin D, Devlin JW, Dexter F, Dworkin RH, Egan TD, Elliott D, Egerod I, Flood P, Fraser GL, Girard TD, Gozal D, Hopkins RO, Kress J, Maze M, Needham DM, Pandharipande P, Riker R, Sessler DI, Shafer SL, Shehabi Y, Spies C, Sun LS, Tung A, Urman RD

Critical care medicine.. 2021 October 149 (10):1684-1693. Epub 1900 01 01.

Composite outcomes for pain clinical trials: considerations for design and interpretation.

Gewandter JS, McDermott MP, Evans S, Katz NP, Markman JD, Simon LS, Turk DC, Dworkin RH

Pain.. 2021 July 1162 (7):1899-1905. Epub 1900 01 01.

Research design considerations for randomized controlled trials of spinal cord stimulation for pain: Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials/Institute of Neuromodulation/International Neuromodulation Society recommendations.

Katz N, Dworkin RH, North R, Thomson S, Eldabe S, Hayek SM, Kopell BH, Markman J, Rezai A, Taylor RS, Turk DC, Buchser E, Fields H, Fiore G, Ferguson M, Gewandter J, Hilker C, Jain R, Leitner A, Loeser J, McNicol E, Nurmikko T, Shipley J, Singh R, Trescot A, van Dongen R, Venkatesan L

Pain.. 2021 July 1162 (7):1935-1956. Epub 1900 01 01.

AAAPT Diagnostic Criteria for Acute Neuropathic Pain.

Doshi TL, Dworkin RH, Polomano RC, Carr DB, Edwards RR, Finnerup NB, Freeman RL, Paice JA, Weisman SJ, Raja SN

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2021 March 1822 (3):616-636. Epub 1900 01 01.

Systematic Review of Research Methods and Reporting Quality of Randomized Clinical Trials of Spinal Cord Stimulation for Pain.

McNicol E, Ferguson M, Bungay K, Rowe EL, Eldabe S, Gewandter JS, Hayek SM, Katz N, Kopell BH, Markman J, Rezai A, Taylor RS, Turk DC, Dworkin RH, North RB, Thomson S

The journal of pain.. 2021 February 22 (2):127-142. Epub 06/20/2020.

Diagnostic criteria for idiopathic small fiber neuropathy: A systematic review.

Haroutounian S, Todorovic MS, Leinders M, Campagnolo M, Gewandter JS, Dworkin RH, Freeman R

Muscle & nerve.. 2021 February 63 (2):170-177. Epub 09/29/2020.

The Prevalence of Psychiatric and Chronic Pain Comorbidities in Fibromyalgia: an ACTTION systematic review.

Kleykamp BA, Ferguson MC, McNicol E, Bixho I, Arnold LM, Edwards RR, Fillingim R, Grol-Prokopczyk H, Turk DC, Dworkin RH

Seminars in arthritis and rheumatism.. 2021 February 51 (1):166-174. Epub 12/29/2020.

Brain Responses to Noxious Stimuli in Patients With Chronic Pain: A Systematic Review and Meta-analysis.

Xu A, Larsen B, Henn A, Baller EB, Scott JC, Sharma V, Adebimpe A, Basbaum AI, Corder G, Dworkin RH, Edwards RR, Woolf CJ, Eickhoff SB, Eickhoff CR, Satterthwaite TD

JAMA network open.. 2021 January 44 (1):e2032236. Epub 01/04/2021.

Essential statistical principles of clinical trials of pain treatments.

Dworkin RH, Evans SR, Mbowe O, McDermott MP

Pain reports.. 2021 6 (1):e863. Epub 12/18/2020.

The ACTTION Guide to Clinical Trials of Pain Treatments, part II: mitigating bias, maximizing value.

Dworkin RH, Kerns RD, McDermott MP, Turk DC, Veasley C

Pain reports.. 2021 6 (1):e886. Epub 01/21/2021.

Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations.

Gewandter JS, Dworkin RH, Turk DC, Farrar JT, Fillingim RB, Gilron I, Markman JD, Oaklander AL, Polydefkis MJ, Raja SN, Robinson JP, Woolf CJ, Ziegler D, Ashburn MA, Burke LB, Cowan P, George SZ, Goli V, Graff OX, Iyengar S, Jay GW, Katz J, Kehlet H, Kitt RA, Kopecky EA, Malamut R, McDermott MP, Palmer P, Rappaport BA, Rauschkolb C, Steigerwald I, Tobias J, Walco GA

Pain reports.. 2021 6 (1):e895. Epub 01/21/2021.

Idiopathic distal sensory polyneuropathy: ACTTION diagnostic criteria.

Freeman R, Gewandter JS, Faber CG, Gibbons C, Haroutounian S, Lauria G, Levine T, Malik RA, Singleton JR, Smith AG, Bell J, Dworkin RH, Feldman E, Herrmann DN, Hoke A, Kolb N, Mansikka H, Oaklander AL, Peltier A, Polydefkis M, Ritt E, Russell JW, Sainati S, Steiner D, Treister R, Üçeyler N

Neurology.. 2020 December 195 (22):1005-1014. Epub 10/14/2020.

Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations.

Smith SM, Dworkin RH, Turk DC, McDermott M, Eccleston C, Farrar JT, Rowbotham MC, Bhangwagar Z, Burke LB, Cowan P, Ellenberg SS, Evans SR, Freeman RL, Garrison LP, Iyengar S, Jadad A, Jensen MP, Junor R, Kamp C, Katz NP, Kesslak JP, Kopecky EA, Lissin D, Markman JD, Mease PJ, O'Connor AB, Patel KV, Raja SN, Sampaio C, Schoenfeld D, Singh J, Steigerwald I, Strand V, Tive LA, Tobias J, Wasan AD, Wilson HD

Pain.. 2020 November 161 (11):2446-2461. Epub 1900 01 01.

Estimands and missing data in clinical trials of chronic pain treatments: advances in design and analysis.

Cai X, Gewandter JS, He H, Turk DC, Dworkin RH, McDermott MP

Pain.. 2020 October 161 (10):2308-2320. Epub 1900 01 01.

John D. Loeser Award Lecture: Size does matter, but it isn't everything: the challenge of modest treatment effects in chronic pain clinical trials.

Smith SM, Fava M, Jensen MP, Mbowe OB, McDermott MP, Turk DC, Dworkin RH

Pain.. 2020 September 161 Suppl 1 (1):S3-S13. Epub 1900 01 01.

The state of clinical outcome assessments for cannabis use disorder clinical trials: A review and research agenda.

Loflin MJE, Kiluk BD, Huestis MA, Aklin WM, Budney AJ, Carroll KM, D'Souza DC, Dworkin RH, Gray KM, Hasin DS, Lee DC, Le Foll B, Levin FR, Lile JA, Mason BJ, McRae-Clark AL, Montoya I, Peters EN, Ramey T, Turk DC, Vandrey R, Weiss RD, Strain EC

Drug and alcohol dependence.. 2020 July 1212 :107993. Epub 04/26/2020.

Chemotherapy-induced peripheral neuropathy (CIPN) and its treatment: an NIH Collaboratory study of claims data.

Gewandter JS, Kleckner AS, Marshall JH, Brown JS, Curtis LH, Bautista J, Dworkin RH, Kleckner IR, Kolb N, Mohile SG, Mustian KM

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.. 2020 June 28 (6):2553-2562. Epub 09/07/2019.

Convergent neural representations of experimentally-induced acute pain in healthy volunteers: A large-scale fMRI meta-analysis.

Xu A, Larsen B, Baller EB, Cobb Scott J, Sharma V, Adebimpe A, Basbaum AI, Dworkin RH, Edwards RR, Woolf CJ, Eickhoff SB, Eickhoff CR, Satterthwaite TD

Neuroscience and biobehavioral reviews.. 2020 May 112 :300-323. Epub 01/15/2020.

Are there really only 2 kinds of people in the world? Evaluating the distribution of change from baseline in pain clinical trials.

Mbowe OB, Gewandter JS, Turk DC, Dworkin RH, McDermott MP

Pain.. 2020 January 161 (1):195-201. Epub 1900 01 01.

Improving Study Conduct and Data Quality in Clinical Trials of Chronic Pain Treatments: IMMPACT Recommendations.

Gewandter JS, Dworkin RH, Turk DC, Devine EG, Hewitt D, Jensen MP, Katz NP, Kirkwood AA, Malamut R, Markman JD, Vrijens B, Burke L, Campbell JN, Carr DB, Conaghan PG, Cowan P, Doyle MK, Edwards RR, Evans SR, Farrar JT, Freeman R, Gilron I, Juge D, Kerns RD, Kopecky EA, McDermott MP, Niebler G, Patel KV, Rauck R, Rice ASC, Rowbotham M, Sessler NE, Simon LS, Singla N, Skljarevski V, Tockarshewsky T, Vanhove GF, Wasan AD, Witter J

The journal of pain.. 2020 21 (9-10):931-942. Epub 12/13/2019.

Craving and opioid use disorder: A scoping review.

Kleykamp BA, De Santis M, Dworkin RH, Huhn AS, Kampman KM, Montoya ID, Preston KL, Ramey T, Smith SM, Turk DC, Walsh R, Weiss RD, Strain EC

Drug and alcohol dependence.. 2019 December 1205 :107639. Epub 10/17/2019.

Clinician-rated measures for distal symmetrical axonal polyneuropathy: ACTTION systematic review.

Gewandter JS, Gibbons CH, Campagnolo M, Lee J, Chaudari J, Ward N, Burke L, Cavaletti G, Herrmann DN, McArthur JC, Russell JW, Smith AG, Smith SM, Turk DC, Dworkin RH, Freeman R

Neurology.. 2019 August 2093 (8):346-360. Epub 07/18/2019.

The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Diagnostic Criteria for Acute Pain Conditions: An Introduction.

Kent ML, Tighe PJ, Bruehl S, Turk DC, Dworkin RH

The journal of pain.. 2019 July 20 (7):743-745. Epub 01/11/2019.

Demonstrating Heterogeneity of Treatment Effects Among Patients: An Overlooked but Important Step Toward Precision Medicine.

Gewandter JS, McDermott MP, He H, Gao S, Cai X, Farrar JT, Katz NP, Markman JD, Senn S, Turk DC, Dworkin RH

Clinical pharmacology and therapeutics.. 2019 July 106 (1):204-210. Epub 03/12/2019.

Navigating trials of personalized pain treatments: we're going to need a bigger boat.

Gewandter JS, McDermott MP, Mbowe O, Edwards RR, Katz NP, Turk DC, Dworkin RH

Pain.. 2019 June 160 (6):1235-1239. Epub 1900 01 01.

Medical Devices to Prevent Opioid Use Disorder: Innovative Approaches to Addressing the Opioid Crisis.

Comer SD, Dworkin RH, Strain EC

JAMA psychiatry.. 2019 April 176 (4):351-352. Epub 1900 01 01.

Design and Reporting Characteristics of Clinical Trials of Select Chronic and Recurrent Pediatric Pain Conditions: An Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks Systematic Review.

Connolly MR, Chaudari JY, Yang X, Ward N, Kitt RA, Herrmann RS, Krane EJ, LeBel AA, Smith SM, Walco GA, Weisman SJ, Turk DC, Dworkin RH, Gewandter JS

The journal of pain.. 2019 April 20 (4):394-404. Epub 09/13/2018.

AAPT Diagnostic Criteria for Peripheral Neuropathic Pain: Focal and Segmental Disorders.

Freeman R, Edwards R, Baron R, Bruehl S, Cruccu G, Dworkin RH, Haroutounian S

The journal of pain.. 2019 April 20 (4):369-393. Epub 12/05/2018.

Systematic review of outcome domains and measures used in psychosocial and pharmacological treatment trials for cannabis use disorder.

Lee DC, Schlienz NJ, Peters EN, Dworkin RH, Turk DC, Strain EC, Vandrey R

Drug and alcohol dependence.. 2019 January 1194 :500-517. Epub 11/15/2018.

Engaging Stakeholders to Promote Safe Anesthesia and Sedation Care in Young Children.

Jackson WM, Chen J, Dworkin RH

Journal of neurosurgical anesthesiology.. 2019 January 31 (1):125-128. Epub 1900 01 01.

Chemotherapy-induced peripheral neuropathy (CIPN) and its treatment: an NIH Collaboratory study of claims data.

Gewandter JS, Kleckner AS, Marshall JH, Brown JS, Curtis LH, Bautista J, Dworkin RH, Kleckner IR, Kolb N, Mohile SG, Mustian KM.

Support Care Cancer. 2019; doi: 10.1007/s00520-019-05063-x.

The ACTTION Guide to Clinical Trials of Pain Treatments: standing on the shoulders of giants.

Dworkin RH, Kerns RD, McDermott MP, Turk DC, Veasley C

Pain reports.. 2019 4 (3):e757. Epub 06/07/2019.

Evaluating Patient-Centered Outcomes in Clinical Trials of Procedural Sedation, Part 2 Safety: Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations.

Ward DS, Williams MR, Berkenbosch JW, Bhatt M, Carlson D, Chappell P, Clark RM, Constant I, Conway A, Cravero J, Dahan A, Dexter F, Dionne R, Dworkin RH, Gan TJ, Gozal D, Green S, Irwin MG, Karan S, Kochman M, Lerman J, Lightdale JR, Litman RS, Mason KP, Miner J, O'Connor RE, Pandharipande P, Riker RR, Roback MG, Sessler DI, Sexton A, Tobin JR, Turk DC, Twersky RS, Urman RD, Weiss M, Wunsch H, Zhao-Wong A

Anesthesia and analgesia.. 2018 November 127 (5):1146-1154. Epub 1900 01 01.

Evaluation of composite responder outcomes of pain intensity and physical function in neuropathic pain clinical trials: an ACTTION individual patient data analysis.

Patel KV, Allen R, Burke L, Farrar JT, Gewandter JS, Gilron I, Katz NP, Markman JD, Marshall SF, Resnick M, Rice ASC, Rowbotham MC, Smith SM, Vanhove GF, Wasan AD, Zhang S, Dworkin RH, Turk DC

Pain.. 2018 November 159 (11):2245-2254. Epub 1900 01 01.

Neuropathic pain clinical trials: factors associated with decreases in estimated drug efficacy.

Finnerup NB, Haroutounian S, Baron R, Dworkin RH, Gilron I, Haanpaa M, Jensen TS, Kamerman PR, McNicol E, Moore A, Raja SN, Andersen NT, Sena ES, Smith BH, Rice AS, Attal N

Pain.. 2018 November 159 (11):2339-2346. Epub 1900 01 01.

A Comparison of the Assay Sensitivity of Average and Worst Pain Intensity in Pharmacologic Trials: An ACTTION Systematic Review and Meta-Analysis.

Smith SM, Jensen MP, He H, Kitt R, Koch J, Pan A, Burke LB, Farrar JT, McDermott MP, Turk DC, Dworkin RH

The journal of pain.. 2018 September 19 (9):953-960. Epub 03/26/2018.

Trial designs for chemotherapy-induced peripheral neuropathy prevention: ACTTION recommendations.

Gewandter JS, Brell J, Cavaletti G, Dougherty PM, Evans S, Howie L, McDermott MP, O'Mara A, Smith AG, Dastros-Pitei D, Gauthier LR, Haroutounian S, Jarpe M, Katz NP, Loprinzi C, Richardson P, Lavoie-Smith EM, Wen PY, Turk DC, Dworkin RH, Freeman R

Neurology.. 2018 August 2891 (9):403-413. Epub 07/27/2018.

Research Design Characteristics of Published Pharmacologic Randomized Clinical Trials for Irritable Bowel Syndrome and Chronic Pelvic Pain Conditions: An ACTTION Systematic Review.

Gewandter JS, Chaudari J, Iwan KB, Kitt R, As-Sanie S, Bachmann G, Clemens Q, Lai HH, Tu F, Verne GN, Vincent K, Wesselmann U, Zhou Q, Turk DC, Dworkin RH, Smith SM

The journal of pain.. 2018 July 19 (7):717-726. Epub 02/02/2018.

Transition to chronic pain: opportunities for novel therapeutics.

Price TJ, Basbaum AI, Bresnahan J, Chambers JF, De Koninck Y, Edwards RR, Ji RR, Katz J, Kavelaars A, Levine JD, Porter L, Schechter N, Sluka KA, Terman GW, Wager TD, Yaksh TL, Dworkin RH

Nature reviews. Neuroscience.. 2018 July 19 (7):383-384. Epub 1900 01 01.

Prospective clinical trial registration: not sufficient, but always necessary.

Smith SM, Dworkin RH

Anaesthesia.. 2018 May 73 (5):538-541. Epub 01/02/2018.

Age-Related Patterns in Cancer Pain and Its Psychosocial Impact: Investigating the Role of Variability in Physical and Mental Health Quality of Life.

Gauthier LR, Dworkin RH, Warr D, Pillai Riddell R, Macpherson AK, Rodin G, Zimmermann C, Lawrence Librach S, Moore M, Shepherd FA, Gagliese L

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2018 April 119 (4):658-676. Epub 1900 01 01.

Efficacy Outcome Measures for Pediatric Procedural Sedation Clinical Trials: An ACTTION Systematic Review.

Williams MR, Nayshtut M, Hoefnagel A, McKeown A, Carlson DW, Cravero J, Lightdale J, Mason KP, Wilson S, Turk DC, Dworkin RH, Ward DS

Anesthesia and analgesia.. 2018 March 126 (3):956-967. Epub 1900 01 01.

Clinical trial designs and models for analgesic medications for acute pain in neonates, infants, toddlers, children, and adolescents: ACTTION recommendations.

Walco GA, Kopecky EA, Weisman SJ, Stinson J, Stevens B, Desjardins PJ, Berde CB, Krane EJ, Anand KJ, Yaster M, Dampier CD, Dworkin RH, Gilron I, Lynn AM, Maxwell LG, Raja S, Schachtel B, Turk DC

Pain.. 2018 February 159 (2):193-205. Epub 1900 01 01.

Measures That Identify Prescription Medication Misuse, Abuse, and Related Events in Clinical Trials: ACTTION Critique and Recommended Considerations.

Smith SM, Jones JK, Katz NP, Roland CL, Setnik B, Trudeau JJ, Wright S, Burke LB, Comer SD, Dart RC, Dionne R, Haddox JD, Jaffe JH, Kopecky EA, Martell BA, Montoya ID, Stanton M, Wasan AD, Turk DC, Dworkin RH

The journal of pain.. 2017 November 18 (11):1287-1294. Epub 05/04/2017.

Chemotherapy-induced peripheral neuropathy clinical trials: Review and recommendations.

Gewandter JS, Freeman R, Kitt RA, Cavaletti G, Gauthier LR, McDermott MP, Mohile NA, Mohlie SG, Smith AG, Tejani MA, Turk DC, Dworkin RH

Neurology.. 2017 August 2289 (8):859-869. Epub 07/26/2017.

Recommendations for Procedural Sedation Clinical Trials.

Ward DS, Williams MR, Turk DC, Dworkin RH, Sessler DI, Dexter F,

Anesthesia and analgesia.. 2017 August 125 (2):703-704. Epub 1900 01 01.

Interpretation of CIs in clinical trials with non-significant results: systematic review and recommendations.

Gewandter JS, McDermott MP, Kitt RA, Chaudari J, Koch JG, Evans SR, Gross RA, Markman JD, Turk DC, Dworkin RH

BMJ open.. 2017 July 187 (7):e017288. Epub 07/18/2017.

The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations.

Smith SM, Dworkin RH, Turk DC, Baron R, Polydefkis M, Tracey I, Borsook D, Edwards RR, Harris RE, Wager TD, Arendt-Nielsen L, Burke LB, Carr DB, Chappell A, Farrar JT, Freeman R, Gilron I, Goli V, Haeussler J, Jensen T, Katz NP, Kent J, Kopecky EA, Lee DA, Maixner W, Markman JD, McArthur JC, McDermott MP, Parvathenani L, Raja SN, Rappaport BA, Rice AS, Rowbotham MC, Tobias JK, Wasan AD, Witter J

The journal of pain.. 2017 July 18 (7):757-777. Epub 02/27/2017.

The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.

Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2017 May 118 (5):947-958. Epub 1900 01 01.

The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.

Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G

The journal of pain.. 2017 May 18 (5):479-489. Epub 1900 01 01.

Content validity of symptom-based measures for diabetic, chemotherapy, and HIV peripheral neuropathy.

Gewandter JS, Burke L, Cavaletti G, Dworkin RH, Gibbons C, Gover TD, Herrmann DN, McArthur Mb JC, McDermott MP, Rappaport BA, Reeve BB, Russell JW, Smith AG, Smith SM, Turk DC, Vinik AI, Freeman R

Muscle & nerve.. 2017 March 55 (3):366-372. Epub 12/23/2016.

Evaluating Patient-Centered Outcomes in Clinical Trials of Procedural Sedation, Part 1 Efficacy: Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations.

Williams MR, Ward DS, Carlson D, Cravero J, Dexter F, Lightdale JR, Mason KP, Miner J, Vargo JJ, Berkenbosch JW, Clark RM, Constant I, Dionne R, Dworkin RH, Gozal D, Grayzel D, Irwin MG, Lerman J, O'Connor RE, Pandharipande P, Rappaport BA, Riker RR, Tobin JR, Turk DC, Twersky RS, Sessler DI

Anesthesia and analgesia.. 2017 March 124 (3):821-830. Epub 1900 01 01.

Reporting of data monitoring boards in publications of randomized clinical trials is often deficient: ACTTION systematic review.

Gewandter JS, Kitt RA, Hunsinger MR, Poku J, Lozano J, Chaudari J, Evans S, Gross RA, McDermott MP, Rowbotham MC, Turk DC, Dworkin RH

Journal of clinical epidemiology.. 2017 March 83 :101-107. Epub 01/23/2017.

Neuropathic pain.

Colloca L, Ludman T, Bouhassira D, Baron R, Dickenson AH, Yarnitsky D, Freeman R, Truini A, Attal N, Finnerup NB, Eccleston C, Kalso E, Bennett DL, Dworkin RH, Raja SN

Nature reviews. Disease primers.. 2017 February 163 :17002. Epub 02/16/2017.

Phenotypes and treatment response: it's difficult to make predictions, especially about the future.

Dworkin RH, Edwards RR

Pain.. 2017 February 158 (2):187-189. Epub 1900 01 01.

Painful chemotherapy-induced peripheral neuropathy: lack of treatment efficacy or the wrong clinical trial methodology?

Gewandter JS, Dworkin RH, Finnerup NB, Mohile NA

Pain.. 2017 January 158 (1):30-33. Epub 1900 01 01.

Reply.

Gewandter JS, Dworkin RH, Finnerup NB, Freeman R, Mohile NA

Pain.. 2017 January 158 (1):182-183. Epub 1900 01 01.

Reporting of Design Features and Analysis Details in Randomized Clinical Trials of Procedural Treatments for Cancer Pain: An ACTTION Systematic Review.

Rothstein D, Kitt RA, Smith SM, Abdi S, Engle MP, McDermott MP, Raja SN, Turk DC, Dworkin RH, Gewandter JS

Regional anesthesia and pain medicine.. 2017 42 (3):392-399. Epub 1900 01 01.

Reporting of cross-over clinical trials of analgesic treatments for chronic pain: Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks systematic review and recommendations.

Gewandter JS, McDermott MP, McKeown A, Hoang K, Iwan K, Kralovic S, Rothstein D, Gilron I, Katz NP, Raja SN, Senn S, Smith SM, Turk DC, Dworkin RH

Pain.. 2016 November 157 (11):2544-2551. Epub 1900 01 01.

Adverse Event Reporting in Clinical Trials of Intravenous and Invasive Pain Treatments: An ACTTION Systematic Review.

Williams MR, McKeown A, Pressman Z, Hunsinger M, Lee K, Coplan P, Gilron I, Katz NP, McDermott MP, Raja SN, Rappaport BA, Rowbotham MC, Turk DC, Dworkin RH, Smith SM

The journal of pain.. 2016 November 17 (11):1137-1149. Epub 08/12/2016.

Participant Preferences for Pharmacologic Chronic Pain Treatment Trial Characteristics: An ACTTION Adaptive Choice-Based Conjoint Study.

Smith SM, Gewandter JS, Kitt RA, Markman JD, Vaughan JA, Cowan P, Kopecky EA, Malamut R, Sadosky A, Tive L, Turk DC, Dworkin RH

The journal of pain.. 2016 November 17 (11):1198-1206. Epub 08/20/2016.

Pain in acquired inflammatory demyelinating polyneuropathies.

Thakur S, Dworkin RH, Freeman R, Gorson KC, Herrmann DN

Pain.. 2016 September 157 (9):1887-1894. Epub 1900 01 01.

Assessment of physical function and participation in chronic pain clinical trials: IMMPACT/OMERACT recommendations.

Taylor AM, Phillips K, Patel KV, Turk DC, Dworkin RH, Beaton D, Clauw DJ, Gignac M, Markman JD, Williams DA, Bujanover S, Burke LB, Carr DB, Choy EH, Conaghan PG, Cowan P, Farrar JT, Freeman R, Gewandter J, Gilron I, Goli V, Gover TD, Haddox JD, Kerns RD, Kopecky EA, Lee DA, Malamut R, Mease P, Rappaport BA, Simon LS, Singh JA, Smith SM, Strand V, Tugwell P, Vanhove GF, Veasley C, Walco GA, Wasan AD, Witter J

Pain.. 2016 September 157 (9):1836-1850. Epub 1900 01 01.

Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations.

Edwards RR, Dworkin RH, Turk DC, Angst MS, Dionne R, Freeman R, Hansson P, Haroutounian S, Arendt-Nielsen L, Attal N, Baron R, Brell J, Bujanover S, Burke LB, Carr D, Chappell AS, Cowan P, Etropolski M, Fillingim RB, Gewandter JS, Katz NP, Kopecky EA, Markman JD, Nomikos G, Porter L, Rappaport BA, Rice AS, Scavone JM, Scholz J, Simon LS, Smith SM, Tobias J, Tockarshewsky T, Veasley C, Versavel M, Wasan AD, Wen W, Yarnitsky D

Pain.. 2016 September 157 (9):1851-1871. Epub 1900 01 01.

Multidimensional Diagnostic Criteria for Chronic Pain: Introduction to the ACTTION-American Pain Society Pain Taxonomy (AAPT).

Dworkin RH, Bruehl S, Fillingim RB, Loeser JD, Terman GW, Turk DC

The journal of pain.. 2016 September 17 (9 Suppl):T1-9. Epub 1900 01 01.

Approaches to Demonstrating the Reliability and Validity of Core Diagnostic Criteria for Chronic Pain.

Bruehl S, Ohrbach R, Sharma S, Widerstrom-Noga E, Dworkin RH, Fillingim RB, Turk DC

The journal of pain.. 2016 September 17 (9 Suppl):T118-31. Epub 1900 01 01.

The Role of Psychosocial Processes in the Development and Maintenance of Chronic Pain.

Edwards RR, Dworkin RH, Sullivan MD, Turk DC, Wasan AD

The journal of pain.. 2016 September 17 (9 Suppl):T70-92. Epub 1900 01 01.

Comment: Clinical outcome assessments in transition.

Dworkin RH

Neurology.. 2016 August 1687 (7 Suppl 1):S10. Epub 1900 01 01.

Meta-analysis with missing study-level sample variance data.

Chowdhry AK, Dworkin RH, McDermott MP

Statistics in medicine.. 2016 July 3035 (17):3021-32. Epub 02/16/2016.

Pain intensity rating training: results from an exploratory study of the ACTTION PROTECCT system.

Smith SM, Amtmann D, Askew RL, Gewandter JS, Hunsinger M, Jensen MP, McDermott MP, Patel KV, Williams M, Bacci ED, Burke LB, Chambers CT, Cooper SA, Cowan P, Desjardins P, Etropolski M, Farrar JT, Gilron I, Huang IZ, Katz M, Kerns RD, Kopecky EA, Rappaport BA, Resnick M, Strand V, Vanhove GF, Veasley C, Versavel M, Wasan AD, Turk DC, Dworkin RH

Pain.. 2016 May 157 (5):1056-1064. Epub 1900 01 01.

Deficiencies in reporting of statistical methodology in recent randomized trials of nonpharmacologic pain treatments: ACTTION systematic review.

Dworkin JD, McKeown A, Farrar JT, Gilron I, Hunsinger M, Kerns RD, McDermott MP, Rappaport BA, Turk DC, Dworkin RH, Gewandter JS

Journal of clinical epidemiology.. 2016 April 72 :56-65. Epub 11/18/2015.

Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations.

Andrews NA, Latrémolière A, Basbaum AI, Mogil JS, Porreca F, Rice AS, Woolf CJ, Currie GL, Dworkin RH, Eisenach JC, Evans S, Gewandter JS, Gover TD, Handwerker H, Huang W, Iyengar S, Jensen MP, Kennedy JD, Lee N, Levine J, Lidster K, Machin I, McDermott MP, McMahon SB, Price TJ, Ross SE, Scherrer G, Seal RP, Sena ES, Silva E, Stone L, Svensson CI, Turk DC, Whiteside G

Pain.. 2016 April 157 (4):901-909. Epub 1900 01 01.

Research design considerations for single-dose analgesic clinical trials in acute pain: IMMPACT recommendations.

Cooper SA, Desjardins PJ, Turk DC, Dworkin RH, Katz NP, Kehlet H, Ballantyne JC, Burke LB, Carragee E, Cowan P, Croll S, Dionne RA, Farrar JT, Gilron I, Gordon DB, Iyengar S, Jay GW, Kalso EA, Kerns RD, McDermott MP, Raja SN, Rappaport BA, Rauschkolb C, Royal MA, Segerdahl M, Stauffer JW, Todd KH, Vanhove GF, Wallace MS, West C, White RE, Wu C

Pain.. 2016 February 157 (2):288-301. Epub 1900 01 01.

Measures of outcome for stimulant trials: ACTTION recommendations and research agenda.

Kiluk BD, Carroll KM, Duhig A, Falk DE, Kampman K, Lai S, Litten RZ, McCann DJ, Montoya ID, Preston KL, Skolnick P, Weisner C, Woody G, Chandler R, Detke MJ, Dunn K, Dworkin RH, Fertig J, Gewandter J, Moeller FG, Ramey T, Ryan M, Silverman K, Strain EC

Drug and alcohol dependence.. 2016 January 1158 :1-7. Epub 11/21/2015.

Two very different types of clinical importance.

Dworkin RH

Contemporary clinical trials.. 2016 January 46 :11. Epub 11/10/2015.

Efficacy Outcome Measures for Procedural Sedation Clinical Trials in Adults: An ACTTION Systematic Review.

Williams MR, McKeown A, Dexter F, Miner JR, Sessler DI, Vargo J, Turk DC, Dworkin RH

Anesthesia and analgesia.. 2016 January 122 (1):152-70. Epub 1900 01 01.

Evaluation of outcome measures for neurogenic claudication: A patient-centered approach.

Markman JD, Gewandter JS, Frazer ME, Pittman C, Cai X, Patel KV, Jahromi BS, Dworkin RH, Burke LB, Farrar JT

Neurology.. 2015 October 685 (14):1250-6. Epub 09/09/2015.

Validation of the Hospital Anxiety and Depression Scale in Patients With Acute Low Back Pain.

Turk DC, Dworkin RH, Trudeau JJ, Benson C, Biondi DM, Katz NP, Kim M

The journal of pain.. 2015 October 16 (10):1012-21. Epub 07/21/2015.

Assay sensitivity of pain intensity versus pain relief in acute pain clinical trials: ACTTION systematic review and meta-analysis.

Singla N, Hunsinger M, Chang PD, McDermott MP, Chowdhry AK, Desjardins PJ, Turk DC, Dworkin RH

The journal of pain.. 2015 August 16 (8):683-91. Epub 04/16/2015.

Reliability is Necessary but Far From Sufficient: How Might the Validity of Pain Ratings be Improved?

Dworkin RH, Laurie B B, Gewandter JS, Smith SM

The Clinical journal of pain.. 2015 July 31 (7):599-602. Epub 1900 01 01.

Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations.

Gewandter JS, Dworkin RH, Turk DC, Farrar JT, Fillingim RB, Gilron I, Markman JD, Oaklander AL, Polydefkis MJ, Raja SN, Robinson JP, Woolf CJ, Ziegler D, Ashburn MA, Burke LB, Cowan P, George SZ, Goli V, Graff OX, Iyengar S, Jay GW, Katz J, Kehlet H, Kitt RA, Kopecky EA, Malamut R, McDermott MP, Palmer P, Rappaport BA, Rauschkolb C, Steigerwald I, Tobias J, Walco GA

Pain.. 2015 July 156 (7):1184-1197. Epub 1900 01 01.

Acute and chronic pain associated with leprosy.

Thakur S, Dworkin RH, Haroun OM, Lockwood DN, Rice AS

Pain.. 2015 June 156 (6):998-1002. Epub 1900 01 01.

A Randomized, Double-blind, Placebo-Controlled Crossover Trial of Oxymorphone Hydrochloride and Propoxyphene/Acetaminophen Combination for the Treatment of Neurogenic Claudication Associated With Lumbar Spinal Stenosis.

Markman JD, Gewandter JS, Frazer ME, Murray NM, Rast SA, McDermott MP, Chowdhry AK, Tompkinson E, Pilcher WH, Walter KA, Dworkin RH

Spine.. 2015 May 1540 (10):684-91. Epub 1900 01 01.

Instruments to Identify Prescription Medication Misuse, Abuse, and Related Events in Clinical Trials: An ACTTION Systematic Review.

Smith SM, Paillard F, McKeown A, Burke LB, Edwards RR, Katz NP, Papadopoulos EJ, Rappaport BA, Slagle A, Strain EC, Wasan AD, Turk DC, Dworkin RH

The journal of pain.. 2015 May 16 (5):389-411. Epub 02/04/2015.

Quality of pain intensity assessment reporting: ACTTION systematic review and recommendations.

Smith SM, Hunsinger M, McKeown A, Parkhurst M, Allen R, Kopko S, Lu Y, Wilson HD, Burke LB, Desjardins P, McDermott MP, Rappaport BA, Turk DC, Dworkin RH

The journal of pain.. 2015 April 16 (4):299-305. Epub 01/28/2015.

Validation of the Short-form McGill Pain Questionnaire-2 (SF-MPQ-2) in acute low back pain.

Dworkin RH, Turk DC, Trudeau JJ, Benson C, Biondi DM, Katz NP, Kim M

The journal of pain.. 2015 April 16 (4):357-66. Epub 01/29/2015.

Reporting of adverse events and statistical details of efficacy estimates in randomized clinical trials of pain in temporomandibular disorders: Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks systematic review.

Gewandter JS, Smith SM, McKeown A, Edwards K, Narula A, Pawlowski JR, Rothstein D, Desjardins PJ, Dworkin SF, Gross RA, Ohrbach R, Rappaport BA, Sessle BJ, Turk DC, Dworkin RH

The Journal of the American Dental Association.. 2015 April 146 (4):246-54.e6. Epub 1900 01 01.

Reporting of sample size calculations in analgesic clinical trials: ACTTION systematic review.

McKeown A, Gewandter JS, McDermott MP, Pawlowski JR, Poli JJ, Rothstein D, Farrar JT, Gilron I, Katz NP, Lin AH, Rappaport BA, Rowbotham MC, Turk DC, Dworkin RH, Smith SM

The journal of pain.. 2015 March 16 (3):199-206.e1-7. Epub 12/04/2014.

Abuse liability-study the intended patient populations.

O'Connor AB, Turk DC, Dworkin RH

Nature reviews. Neurology.. 2015 March 11 (3):182. Epub 02/10/2015.

Neurocognitive Changes after Sustained Ketamine Administration in Children with Chronic Pain.

Bredlau AL, Harel BT, McDermott MP, Dworkin RH, Korones DN, Dolan JG, Adams HR

Journal of palliative care & medicine. 2015 March 5 (2)Epub 03/27/2015.

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.

Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpää M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M

The Lancet. Neurology.. 2015 February 14 (2):162-73. Epub 01/07/2015.

Double-blind, randomized, controlled, crossover trial of pregabalin for neurogenic claudication.

Markman JD, Frazer ME, Rast SA, McDermott MP, Gewandter JS, Chowdhry AK, Czerniecka K, Pilcher WH, Simon LS, Dworkin RH

Neurology.. 2015 January 2084 (3):265-72. Epub 12/10/2014.

Data interpretation in analgesic clinical trials with statistically nonsignificant primary analyses: an ACTTION systematic review.

Gewandter JS, McKeown A, McDermott MP, Dworkin JD, Smith SM, Gross RA, Hunsinger M, Lin AH, Rappaport BA, Rice AS, Rowbotham MC, Williams MR, Turk DC, Dworkin RH

The journal of pain.. 2015 January 16 (1):3-10. Epub 10/23/2014.

Suicidal ideation and behavior associated with antidepressant medications: Implications for the treatment of chronic pain.

Pereira A, Conwell Y, Gitlin MJ, Dworkin RH

Pain.. 2014 December 155 (12):2471-2475. Epub 08/27/2014.

Meta-analysis of assay sensitivity and study features in clinical trials of pharmacologic treatments for osteoarthritis pain.

Dworkin RH, Turk DC, Peirce-Sandner S, He H, McDermott MP, Hochberg MC, Jordan JM, Katz NP, Lin AH, Neogi T, Rappaport BA, Simon LS, Strand V

Arthritis & rheumatology.. 2014 December 66 (12):3327-36. Epub 1900 01 01.

Reporting of intention-to-treat analyses in recent analgesic clinical trials: ACTTION systematic review and recommendations.

Gewandter JS, McDermott MP, McKeown A, Smith SM, Pawlowski JR, Poli JJ, Rothstein D, Williams MR, Bujanover S, Farrar JT, Gilron I, Katz NP, Rowbotham MC, Turk DC, Dworkin RH

Pain.. 2014 December 155 (12):2714-2719. Epub 10/02/2014.

Adverse event reporting in nonpharmacologic, noninterventional pain clinical trials: ACTTION systematic review.

Hunsinger M, Smith SM, Rothstein D, McKeown A, Parkhurst M, Hertz S, Katz NP, Lin AH, McDermott MP, Rappaport BA, Turk DC, Dworkin RH

Pain.. 2014 November 155 (11):2253-62. Epub 08/12/2014.

The ACTTION-APS Pain Taxonomy initiative: response to Henriques et al.

Fillingim RB, Dworkin RH, Turk DC

The journal of pain.. 2014 November 15 (11):1201-1202. Epub 10/31/2014.

How transparent are migraine clinical trials? Repository of Registered Migraine Trials (RReMiT).

Dufka FL, Dworkin RH, Rowbotham MC

Neurology.. 2014 October 783 (15):1372-81. Epub 09/05/2014.

Back to the future: the need to resolve analgesic efficacy in human immunodeficiency virus neuropathy.

Dworkin RH, McDermott MP

Pain.. 2014 October 155 (10):1913-1915. Epub 07/24/2014.

Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations.

Gewandter JS, Dworkin RH, Turk DC, McDermott MP, Baron R, Gastonguay MR, Gilron I, Katz NP, Mehta C, Raja SN, Senn S, Taylor C, Cowan P, Desjardins P, Dimitrova R, Dionne R, Farrar JT, Hewitt DJ, Iyengar S, Jay GW, Kalso E, Kerns RD, Leff R, Leong M, Petersen KL, Ravina BM, Rauschkolb C, Rice AS, Rowbotham MC, Sampaio C, Sindrup SH, Stauffer JW, Steigerwald I, Stewart J, Tobias J, Treede RD, Wallace M, White RE

Pain.. 2014 September 155 (9):1683-1695. Epub 05/24/2014.

Reporting of missing data and methods used to accommodate them in recent analgesic clinical trials: ACTTION systematic review and recommendations.

Gewandter JS, McDermott MP, McKeown A, Smith SM, Williams MR, Hunsinger M, Farrar J, Turk DC, Dworkin RH

Pain.. 2014 September 155 (9):1871-1877. Epub 06/30/2014.

Acute and chronic pain associated with Lyme borreliosis: clinical characteristics and pathophysiologic mechanisms.

Zimering JH, Williams MR, Eiras ME, Fallon BA, Logigian EL, Dworkin RH

Pain.. 2014 August 155 (8):1435-1438. Epub 04/24/2014.

Effect of variability in the 7-day baseline pain diary on the assay sensitivity of neuropathic pain randomized clinical trials: an ACTTION study.

Farrar JT, Troxel AB, Haynes K, Gilron I, Kerns RD, Katz NP, Rappaport BA, Rowbotham MC, Tierney AM, Turk DC, Dworkin RH

Pain.. 2014 August 155 (8):1622-1631. Epub 05/14/2014.

RReACT goes global: perils and pitfalls of constructing a global open-access database of registered analgesic clinical trials and trial results.

Munch T, Dufka FL, Greene K, Smith SM, Dworkin RH, Rowbotham MC

Pain.. 2014 July 155 (7):1313-1317. Epub 04/13/2014.

Validation of the short-form McGill pain questionnaire-2 in younger and older people with cancer pain.

Gauthier LR, Young A, Dworkin RH, Rodin G, Zimmermann C, Warr D, Librach SL, Moore M, Shepherd FA, Riddell RP, Macpherson A, Melzack R, Gagliese L

The journal of pain.. 2014 July 15 (7):756-70. Epub 04/26/2014.

Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.

Hershman DL, Lacchetti C, Dworkin RH, Lavoie Smith EM, Bleeker J, Cavaletti G, Chauhan C, Gavin P, Lavino A, Lustberg MB, Paice J, Schneider B, Smith ML, Smith T, Terstriep S, Wagner-Johnston N, Bak K, Loprinzi CL

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2014 June 2032 (18):1941-67. Epub 04/14/2014.

Disclosure of authorship contributions in analgesic clinical trials and related publications: ACTTION systematic review and recommendations.

Hunsinger M, Smith SM, McKeown A, Parkhurst M, Gross RA, Lin AH, McDermott MP, Rappaport BA, Turk DC, Dworkin RH

Pain.. 2014 June 155 (6):1059-1063. Epub 12/12/2013.

HIV-associated distal neuropathic pain is associated with smaller total cerebral cortical gray matter.

Keltner JR, Fennema-Notestine C, Vaida F, Wang D, Franklin DR, Dworkin RH, Sanders C, McCutchan JA, Archibald SL, Miller DJ, Kesidis G, Cushman C, Kim SM, Abramson I, Taylor MJ, Theilmann RJ, Julaton MD, Notestine RJ, Corkran S, Cherner M, Duarte NA, Alexander T, Robinson-Papp J, Gelman BB, Simpson DM, Collier AC, Marra CM, Morgello S, Brown G, Grant I, Atkinson JH, Jernigan TL, Ellis RJ,

Journal of neurovirology.. 2014 June 20 (3):209-18. Epub 02/19/2014.

EMA401, an orally administered highly selective angiotensin II type 2 receptor antagonist, as a novel treatment for postherpetic neuralgia: a randomised, double-blind, placebo-controlled phase 2 clinical trial.

Rice AS, Dworkin RH, McCarthy TD, Anand P, Bountra C, McCloud PI, Hill J, Cutter G, Kitson G, Desem N, Raff M,

Lancet.. 2014 May 10383 (9929):1637-1647. Epub 02/05/2014.

Response to letter to the editor.

Dworkin RH, O'Connor AB, Kent J, Mackey SC, Raja SN, Stacey BR, Levy RM, Backonja M, Baron R, Harke H, Loeser JD, Treede RD, Turk DC, Wells CD

Pain.. 2014 May 155 (5):1045-1046. Epub 02/07/2014.

Interpreting patient treatment response in analgesic clinical trials: implications for genotyping, phenotyping, and personalized pain treatment.

Dworkin RH, McDermott MP, Farrar JT, O'Connor AB, Senn S

Pain.. 2014 March 155 (3):457-460. Epub 09/23/2013.

Reporting of primary analyses and multiplicity adjustment in recent analgesic clinical trials: ACTTION systematic review and recommendations.

Gewandter JS, Smith SM, McKeown A, Burke LB, Hertz SH, Hunsinger M, Katz NP, Lin AH, McDermott MP, Rappaport BA, Williams MR, Turk DC, Dworkin RH

Pain.. 2014 March 155 (3):461-466. Epub 11/23/2013.

The ACTTION-American Pain Society Pain Taxonomy (AAPT): an evidence-based and multidimensional approach to classifying chronic pain conditions.

Fillingim RB, Bruehl S, Dworkin RH, Dworkin SF, Loeser JD, Turk DC, Widerstrom-Noga E, Arnold L, Bennett R, Edwards RR, Freeman R, Gewandter J, Hertz S, Hochberg M, Krane E, Mantyh PW, Markman J, Neogi T, Ohrbach R, Paice JA, Porreca F, Rappaport BA, Smith SM, Smith TJ, Sullivan MD, Verne GN, Wasan AD, Wesselmann U

The journal of pain.. 2014 March 15 (3):241-9. Epub 1900 01 01.

Discrepancies between registered and published primary outcome specifications in analgesic trials: ACTTION systematic review and recommendations.

Smith SM, Wang AT, Pereira A, Daniel Chang R, McKeown A, Greene K, Rowbotham MC, Burke LB, Coplan P, Gilron I, Hertz SH, Katz NP, Lin AH, McDermott MP, Papadopoulos EJ, Rappaport BA, Sweeney M, Turk DC, Dworkin RH

Pain.. 2013 December 154 (12):2769-2774. Epub 08/17/2013.

Is mild persisting pain too insignificant to be considered a chronic pain condition?

Dworkin RH

The Clinical journal of pain.. 2013 November 29 (11):1013. Epub 1900 01 01.

Interventional management of neuropathic pain: NeuPSIG recommendations.

Dworkin RH, O'Connor AB, Kent J, Mackey SC, Raja SN, Stacey BR, Levy RM, Backonja M, Baron R, Harke H, Loeser JD, Treede RD, Turk DC, Wells CD

Pain.. 2013 November 154 (11):2249-2261. Epub 06/06/2013.

Classification and definition of misuse, abuse, and related events in clinical trials: ACTTION systematic review and recommendations.

Smith SM, Dart RC, Katz NP, Paillard F, Adams EH, Comer SD, Degroot A, Edwards RR, David Haddox J, Jaffe JH, Jones CM, Kleber HD, Kopecky EA, Markman JD, Montoya ID, O'Brien C, Roland CL, Stanton M, Strain EC, Vorsanger G, Wasan AD, Weiss RD, Turk DC, Dworkin RH

Pain.. 2013 November 154 (11):2287-2296. Epub 06/20/2013.

Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations.

O'Connor AB, Turk DC, Dworkin RH, Katz NP, Colucci R, Haythornthwaite JA, Klein M, O'Brien C, Posner K, Rappaport BA, Reisfield G, Adams EH, Balster RL, Bigelow GE, Burke LB, Comer SD, Cone E, Cowan P, Denisco RA, Farrar JT, Foltin RW, Haddox JD, Hertz S, Jay GW, Junor R, Kopecky EA, Leiderman DB, McDermott MP, Palmer PP, Raja SN, Rauschkolb C, Rowbotham MC, Sampaio C, Setnik B, Smith SM, Sokolowska M, Stauffer JW, Walsh SL, Zacny JP

Pain.. 2013 November 154 (11):2324-2334. Epub 1900 01 01.

Ketamine for pain in adults and children with cancer: a systematic review and synthesis of the literature.

Bredlau AL, Thakur R, Korones DN, Dworkin RH

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2013 October 14 (10):1505-17. Epub 08/05/2013.

Assay sensitivity and study features in neuropathic pain trials: an ACTTION meta-analysis.

Dworkin RH, Turk DC, Peirce-Sandner S, He H, McDermott MP, Farrar JT, Katz NP, Lin AH, Rappaport BA, Rowbotham MC

Neurology.. 2013 July 281 (1):67-75. Epub 05/22/2013.

Oral ketamine for children with chronic pain: a pilot phase 1 study.

Bredlau AL, McDermott MP, Adam HR, Dworkin RH, Venuto C, Fisher SG, Dolan JG, Korones DN

The Journal of pediatrics.. 2013 July 163 (1):194-200.e1. Epub 02/10/2013.

Experience and challenges presented by a multicenter crossover study of combination analgesic therapy for the treatment of painful HIV-associated polyneuropathies.

Harrison T, Miyahara S, Lee A, Evans S, Bastow B, Simpson D, Gilron I, Dworkin R, Daar ES, Wieclaw L, Clifford DB,

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2013 July 14 (7):1039-47. Epub 04/08/2013.

Adverse event assessment, analysis, and reporting in recent published analgesic clinical trials: ACTTION systematic review and recommendations.

Smith SM, Wang AT, Katz NP, McDermott MP, Burke LB, Coplan P, Gilron I, Hertz SH, Lin AH, Rappaport BA, Rowbotham MC, Sampaio C, Sweeney M, Turk DC, Dworkin RH

Pain.. 2013 July 154 (7):997-1008. Epub 03/14/2013.

Suicidality associated with antiepileptic drugs: implications for the treatment of neuropathic pain and fibromyalgia.

Pereira A, Gitlin MJ, Gross RA, Posner K, Dworkin RH

Pain.. 2013 March 154 (3):345-349. Epub 01/11/2013.

A standard database format for clinical trials of pain treatments: an ACTTION-CDISC initiative.

Dworkin RH, Allen R, Kopko S, Lu Y, Turk DC, Burke LB, Desjardins P, Etropolski M, Hewitt DJ, Jayawardena S, Lin AH, Malamut R, Michel D, Ottinger J, Peloso P, Pucino F, Rappaport BA, Skljarevski V, St Peter D, Timinski S, West CR, Wilson HD

Pain.. 2013 January 154 (1):11-14. Epub 10/26/2012.

Adherence to CONSORT harms-reporting recommendations in publications of recent analgesic clinical trials: an ACTTION systematic review.

Smith SM, Chang RD, Pereira A, Shah N, Gilron I, Katz NP, Lin AH, McDermott MP, Rappaport BA, Rowbotham MC, Sampaio C, Turk DC, Dworkin RH

Pain.. 2012 December 153 (12):2415-2421. Epub 09/15/2012.

Core outcome measures for opioid abuse liability laboratory assessment studies in humans: IMMPACT recommendations.

Comer SD, Zacny JP, Dworkin RH, Turk DC, Bigelow GE, Foltin RW, Jasinski DR, Sellers EM, Adams EH, Balster R, Burke LB, Cerny I, Colucci RD, Cone E, Cowan P, Farrar JT, Haddox JD, Haythornthwaite JA, Hertz S, Jay GW, Johanson CE, Junor R, Katz NP, Klein M, Kopecky EA, Leiderman DB, McDermott MP, O'Brien C, O'Connor AB, Palmer PP, Raja SN, Rappaport BA, Rauschkolb C, Rowbotham MC, Sampaio C, Setnik B, Sokolowska M, Stauffer JW, Walsh SL

Pain.. 2012 December 153 (12):2315-2324. Epub 09/19/2012.

Mechanism-based treatment of pain.

Dworkin RH

Pain.. 2012 November 153 (11):2300. Epub 09/21/2012.

Research design considerations for clinical studies of abuse-deterrent opioid analgesics: IMMPACT recommendations.

Turk DC, O'Connor AB, Dworkin RH, Chaudhry A, Katz NP, Adams EH, Brownstein JS, Comer SD, Dart R, Dasgupta N, Denisco RA, Klein M, Leiderman DB, Lubran R, Rappaport BA, Zacny JP, Ahdieh H, Burke LB, Cowan P, Jacobs P, Malamut R, Markman J, Michna E, Palmer P, Peirce-Sandner S, Potter JS, Raja SN, Rauschkolb C, Roland CL, Webster LR, Weiss RD, Wolf K

Pain.. 2012 October 153 (10):1997-2008. Epub 07/05/2012.

A snapshot and scorecard for analgesic clinical trials for chronic pain: the RReACT database.

Greene K, Dworkin RH, Rowbotham MC

Pain.. 2012 September 153 (9):1794-1797. Epub 07/15/2012.

Considerations for improving assay sensitivity in chronic pain clinical trials: IMMPACT recommendations.

Dworkin RH, Turk DC, Peirce-Sandner S, Burke LB, Farrar JT, Gilron I, Jensen MP, Katz NP, Raja SN, Rappaport BA, Rowbotham MC, Backonja MM, Baron R, Bellamy N, Bhagwagar Z, Costello A, Cowan P, Fang WC, Hertz S, Jay GW, Junor R, Kerns RD, Kerwin R, Kopecky EA, Lissin D, Malamut R, Markman JD, McDermott MP, Munera C, Porter L, Rauschkolb C, Rice AS, Sampaio C, Skljarevski V, Sommerville K, Stacey BR, Steigerwald I, Tobias J, Trentacosti AM, Wasan AD, Wells GA, Williams J, Witter J, Ziegler D

Pain.. 2012 June 153 (6):1148-1158. Epub 04/09/2012.

Is treatment of postherpetic neuralgia in the community consistent with evidence-based recommendations?

Dworkin RH, Panarites CJ, Armstrong EP, Malone DC, Pham SV

Pain.. 2012 April 153 (4):869-875. Epub 02/21/2012.

What is localized neuropathic pain? A first proposal to characterize and define a widely used term.

Mick G, Baron R, Finnerup NB, Hans G, Kern KU, Brett B, Dworkin RH

Pain management.. 2012 January 2 (1):71-7. Epub 1900 01 01.

Health-related quality of life 'well-being' in HIV distal neuropathic pain is more strongly associated with depression severity than with pain intensity.

Keltner JR, Vaida F, Ellis RJ, Moeller-Bertram T, Fitzsimmons C, Duarte NA, Robinson-Papp J, Dworkin RH, Clifford DB, McArthur JC, Simpson DM, Collier AC, Marra CM, Atkinson JH, Grant I,

Psychosomatics.. 2012 53 (4):380-6. Epub 1900 01 01.

Considerations for extrapolating evidence of acute and chronic pain analgesic efficacy.

Dworkin RH, Turk DC, Basch E, Berger A, Cleeland C, Farrar JT, Haythornthwaite JA, Jensen MP, Kerns RD, Markman J, Porter L, Raja SN, Ross E, Todd K, Wallace M, Woolf CJ

Pain.. 2011 August 152 (8):1705-1708. Epub 03/10/2011.

OMERACT 10 Patient Perspective Virtual Campus: valuing health; measuring outcomes in rheumatoid arthritis fatigue, RA sleep, arthroplasty, and systemic sclerosis; and clinical significance of changes in health.

Kirwan JR, Boonen A, Harrison MJ, Hewlett SE, Wells GA, Singh JA, Furst DE, Dworkin RH

The Journal of rheumatology.. 2011 August 38 (8):1728-34. Epub 1900 01 01.

Accelerating the development of improved analgesic treatments: the ACTION public-private partnership.

Dworkin RH, Turk DC

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2011 July 12 Suppl 3 :S109-17. Epub 1900 01 01.

Outcome measures in placebo-controlled trials of osteoarthritis: responsiveness to treatment effects in the REPORT database.

Dworkin RH, Peirce-Sandner S, Turk DC, McDermott MP, Gibofsky A, Simon LS, Farrar JT, Katz NP

Osteoarthritis and cartilage. 2011 May 19 (5):483-92. Epub 03/23/2011.

Assessing symptom profiles in neuropathic pain clinical trials: can it improve outcome?

Attal N, Bouhassira D, Baron R, Dostrovsky J, Dworkin RH, Finnerup N, Gourlay G, Haanpaa M, Raja S, Rice AS, Simpson D, Treede RD

European journal of pain : EJP.. 2011 May 15 (5):441-3. Epub 03/31/2011.

Healthcare utilization in people with postherpetic neuralgia and painful diabetic peripheral neuropathy.

Dworkin RH, Panarites CJ, Armstrong EP, Malone DC, Pham SV

Journal of the American Geriatrics Society.. 2011 May 59 (5):827-36. Epub 1900 01 01.

Treatment satisfaction in osteoarthritis and chronic low back pain: the role of pain, physical and emotional functioning, sleep, and adverse events.

Dworkin RH, Jensen MP, Gould E, Jones BA, Xiang Q, Galer BS, Gammaitoni AR

The journal of pain.. 2011 April 12 (4):416-24. Epub 1900 01 01.

Evidence-based clinical trial design for chronic pain pharmacotherapy: a blueprint for ACTION.

Dworkin RH, Turk DC, Katz NP, Rowbotham MC, Peirce-Sandner S, Cerny I, Clingman CS, Eloff BC, Farrar JT, Kamp C, McDermott MP, Rappaport BA, Sanhai WR

Pain.. 2011 March 152 (3 Suppl):S107-S115. Epub 12/09/2010.

Association of self-reported painful symptoms with clinical and neurophysiologic signs in HIV-associated sensory neuropathy.

Robinson-Papp J, Morgello S, Vaida F, Fitzsimons C, Simpson DM, Elliott KJ, Al-Lozi M, Gelman BB, Clifford D, Marra CM, McCutchan JA, Atkinson JH, Dworkin RH, Grant I, Ellis R

Pain.. 2010 December 151 (3):732-736. Epub 09/20/2010.

The prevalence of chronic pain in United States adults: results of an Internet-based survey.

Johannes CB, Le TK, Zhou X, Johnston JA, Dworkin RH

The journal of pain.. 2010 November 11 (11):1230-9. Epub 08/25/2010.

Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trial.

Foster DC, Kotok MB, Huang LS, Watts A, Oakes D, Howard FM, Poleshuck EL, Stodgell CJ, Dworkin RH

Obstetrics and gynecology.. 2010 September 116 (3):583-593. Epub 1900 01 01.

Broadening the spectrum of controls for skin biopsy in painful neuropathies.

Herrmann DN, O'Connor AB, Schwid SR, Da Y, Goodman AD, Rafferty J, Donahue S, Dworkin RH

Muscle & nerve.. 2010 September 42 (3):436-8. Epub 1900 01 01.

Placebo and treatment group responses in postherpetic neuralgia vs. painful diabetic peripheral neuropathy clinical trials in the REPORT database.

Dworkin RH, Turk DC, Peirce-Sandner S, McDermott MP, Farrar JT, Hertz S, Katz NP, Raja SN, Rappaport BA

Pain.. 2010 July 150 (1):12-16. Epub 03/03/2010.

Research design considerations for confirmatory chronic pain clinical trials: IMMPACT recommendations.

Dworkin RH, Turk DC, Peirce-Sandner S, Baron R, Bellamy N, Burke LB, Chappell A, Chartier K, Cleeland CS, Costello A, Cowan P, Dimitrova R, Ellenberg S, Farrar JT, French JA, Gilron I, Hertz S, Jadad AR, Jay GW, Kalliomäki J, Katz NP, Kerns RD, Manning DC, McDermott MP, McGrath PJ, Narayana A, Porter L, Quessy S, Rappaport BA, Rauschkolb C, Reeve BB, Rhodes T, Sampaio C, Simpson DM, Stauffer JW, Stucki G, Tobias J, White RE, Witter J

Pain.. 2010 May 149 (2):177-193. Epub 03/06/2010.

Continued high prevalence and adverse clinical impact of human immunodeficiency virus-associated sensory neuropathy in the era of combination antiretroviral therapy: the CHARTER Study.

Ellis RJ, Rosario D, Clifford DB, McArthur JC, Simpson D, Alexander T, Gelman BB, Vaida F, Collier A, Marra CM, Ances B, Atkinson JH, Dworkin RH, Morgello S, Grant I,

Archives of neurology.. 2010 May 67 (5):552-8. Epub 1900 01 01.

Prevention strategies for herpes zoster and post-herpetic neuralgia.

Levin MJ, Gershon AA, Dworkin RH, Brisson M, Stanberry L

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.. 2010 May 48 Suppl 1 (Suppl 1):S14-9. Epub 1900 01 01.

Impact of postherpetic neuralgia and painful diabetic peripheral neuropathy on health care costs.

Dworkin RH, Malone DC, Panarites CJ, Armstrong EP, Pham SV

The journal of pain.. 2010 April 11 (4):360-8. Epub 10/22/2009.

Preventing chronic postsurgical pain: how much of a difference makes a difference?

Dworkin RH, McDermott MP, Raja SN

Anesthesiology.. 2010 March 112 (3):516-8. Epub 1900 01 01.

Recommendations for the pharmacological management of neuropathic pain: an overview and literature update.

Dworkin RH, O'Connor AB, Audette J, Baron R, Gourlay GK, Haanpää ML, Kent JL, Krane EJ, Lebel AA, Levy RM, Mackey SC, Mayer J, Miaskowski C, Raja SN, Rice AS, Schmader KE, Stacey B, Stanos S, Treede RD, Turk DC, Walco GA, Wells CD

Mayo Clinic proceedings.. 2010 March 85 (3 Suppl):S3-14. Epub 1900 01 01.

Neuropathic pain in children: Special considerations.

Walco GA, Dworkin RH, Krane EJ, LeBel AA, Treede RD

Mayo Clinic proceedings.. 2010 March 85 (3 Suppl):S33-41. Epub 1900 01 01.

Interpreting the clinical importance of group differences in chronic pain clinical trials: IMMPACT recommendations.

Dworkin RH, Turk DC, McDermott MP, Peirce-Sandner S, Burke LB, Cowan P, Farrar JT, Hertz S, Raja SN, Rappaport BA, Rauschkolb C, Sampaio C

Pain.. 2009 December 146 (3):238-244. Epub 1900 01 01.

Introduction: Recommendations for the diagnosis, assessment, and treatment of neuropathic pain.

Dworkin RH

The American journal of medicine.. 2009 October 122 (10 Suppl):S1-2. Epub 1900 01 01.

Treatment of neuropathic pain: an overview of recent guidelines.

O'Connor AB, Dworkin RH

The American journal of medicine.. 2009 October 122 (10 Suppl):S22-32. Epub 1900 01 01.

Development and initial validation of an expanded and revised version of the Short-form McGill Pain Questionnaire (SF-MPQ-2).

Dworkin RH, Turk DC, Revicki DA, Harding G, Coyne KS, Peirce-Sandner S, Bhagwat D, Everton D, Burke LB, Cowan P, Farrar JT, Hertz S, Max MB, Rappaport BA, Melzack R

Pain.. 2009 July 144 (1-2):35-42. Epub 04/07/2009.

Non-steroidal anti-inflammatory drugs for neuropathic pain: how do we explain continued widespread use?

Vo T, Rice AS, Dworkin RH

Pain.. 2009 June 143 (3):169-171. Epub 04/10/2009.

A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster.

Dworkin RH, Barbano RL, Tyring SK, Betts RF, McDermott MP, Pennella-Vaughan J, Bennett GJ, Berber E, Gnann JW, Irvine C, Kamp C, Kieburtz K, Max MB, Schmader KE

Pain.. 2009 April 142 (3):209-217. Epub 02/04/2009.

The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.

Foster DC, Kotok MB, Huang LS, Watts A, Oakes D, Howard FM, Stodgell CJ, Dworkin RH

Obstetrics and gynecology.. 2009 April 113 (4):825-832. Epub 1900 01 01.

Polyunsaturated fatty acids and their potential therapeutic role in multiple sclerosis.

Mehta LR, Dworkin RH, Schwid SR

Nature clinical practice. Neurology.. 2009 February 5 (2):82-92. Epub 1900 01 01.

Evidence-based treatment of chronic neuropathic pain using nonopioid pharmacotherapy

O'Connor AB, Dworkin RH.

Continuum lifelong learning in neurology. 2009; 15: 69-82.

Pregabalin in the treatment of refractory neuropathic pain: results of a 15-month open-label trial.

Stacey BR, Dworkin RH, Murphy K, Sharma U, Emir B, Griesing T

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2008 November 9 (8):1202-8. Epub 03/11/2008.

Analyzing multiple endpoints in clinical trials of pain treatments: IMMPACT recommendations. Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials.

Turk DC, Dworkin RH, McDermott MP, Bellamy N, Burke LB, Chandler JM, Cleeland CS, Cowan P, Dimitrova R, Farrar JT, Hertz S, Heyse JF, Iyengar S, Jadad AR, Jay GW, Jermano JA, Katz NP, Manning DC, Martin S, Max MB, McGrath P, McQuay HJ, Quessy S, Rappaport BA, Revicki DA, Rothman M, Stauffer JW, Svensson O, White RE, Witter J

Pain.. 2008 October 31139 (3):485-493. Epub 08/15/2008.

Core outcome domains and measures for pediatric acute and chronic/recurrent pain clinical trials: PedIMMPACT recommendations.

McGrath PJ, Walco GA, Turk DC, Dworkin RH, Brown MT, Davidson K, Eccleston C, Finley GA, Goldschneider K, Haverkos L, Hertz SH, Ljungman G, Palermo T, Rappaport BA, Rhodes T, Schechter N, Scott J, Sethna N, Svensson OK, Stinson J, von Baeyer CL, Walker L, Weisman S, White RE, Zajicek A, Zeltzer L,

The journal of pain.. 2008 September 9 (9):771-83. Epub 06/17/2008.

Identifying important outcome domains for chronic pain clinical trials: an IMMPACT survey of people with pain.

Turk DC, Dworkin RH, Revicki D, Harding G, Burke LB, Cella D, Cleeland CS, Cowan P, Farrar JT, Hertz S, Max MB, Rappaport BA

Pain.. 2008 July 15137 (2):276-285. Epub 10/15/2007.

Pain associated with multiple sclerosis: systematic review and proposed classification.

O'Connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH

Pain.. 2008 July 137 (1):96-111. Epub 10/24/2007.

Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP).

Harpaz R, Ortega-Sanchez IR, Seward JF,

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports. 2008 June 657 (RR-5):1-30; quiz CE2-4. Epub 1900 01 01.

Health care expenditure burden of persisting herpes zoster pain.

Dworkin RH, White R, O'Connor AB, Hawkins K

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2008 April 9 (3):348-53. Epub 1900 01 01.

Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations.

Dworkin RH, Turk DC, Wyrwich KW, Beaton D, Cleeland CS, Farrar JT, Haythornthwaite JA, Jensen MP, Kerns RD, Ader DN, Brandenburg N, Burke LB, Cella D, Chandler J, Cowan P, Dimitrova R, Dionne R, Hertz S, Jadad AR, Katz NP, Kehlet H, Kramer LD, Manning DC, McCormick C, McDermott MP, McQuay HJ, Patel S, Porter L, Quessy S, Rappaport BA, Rauschkolb C, Revicki DA, Rothman M, Schmader KE, Stacey BR, Stauffer JW, von Stein T, White RE, Witter J, Zavisic S

The journal of pain.. 2008 February 9 (2):105-21. Epub 12/11/2007.

Clinical trial outcome in neuropathic pain: relationship to study characteristics.

Katz J, Finnerup NB, Dworkin RH

Neurology.. 2008 January 2270 (4):263-72. Epub 1900 01 01.

Natural history and treatment of herpes zoster.

Schmader KE, Dworkin RH

The journal of pain.. 2008 January 9 (1 Suppl 1):S3-9. Epub 1900 01 01.

Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia.

Dworkin RH, Gnann JW, Oaklander AL, Raja SN, Schmader KE, Whitley RJ

The journal of pain.. 2008 January 9 (1 Suppl 1):S37-44. Epub 1900 01 01.

Randomized clinical trials of pregabalin for neuropathic pain: methods, results, and implications

Dworkin RH, Thakur R, Griesing T, Sharma U, Young JP.

Progress in neurotherapeutics and neuropsychopharmacology. 2008; 3: 167-87.

National Institute of Neurological Disorders and Stroke (NINDS): advances in understanding and treating neuropathy, 24-25 October 2006; Bethesda, Maryland

Feldman EL, Cornblath DR, Porter J, Dworkin RH, Scherer S.

Journal of the peripheral nervous system. 2008; 13: 1-6.

Pharmacologic management of neuropathic pain: evidence-based recommendations.

Dworkin RH, O'Connor AB, Backonja M, Farrar JT, Finnerup NB, Jensen TS, Kalso EA, Loeser JD, Miaskowski C, Nurmikko TJ, Portenoy RK, Rice AS, Stacey BR, Treede RD, Turk DC, Wallace MS

Pain.. 2007 December 5132 (3):237-251. Epub 10/24/2007.

Epidemiology, public health burden, and treatment of diabetic peripheral neuropathic pain: a review.

Barrett AM, Lucero MA, Le T, Robinson RL, Dworkin RH, Chappell AS

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2007 September 8 Suppl 2 :S50-62. Epub 1900 01 01.

Healthcare costs of acute and chronic pain associated with a diagnosis of herpes zoster.

Dworkin RH, White R, O'Connor AB, Baser O, Hawkins K

Journal of the American Geriatrics Society.. 2007 August 55 (8):1168-75. Epub 1900 01 01.

The impact of neuropathic pain on health-related quality of life: review and implications.

Jensen MP, Chodroff MJ, Dworkin RH

Neurology.. 2007 April 1068 (15):1178-82. Epub 1900 01 01.

Inadequate evidence for a revised definition of postherpetic neuralgia (PHN).

Dworkin RH

Pain.. 2007 March 128 (1-2):189-90; author reply 190-2. Epub 01/19/2007.

Symptom profiles differ in patients with neuropathic versus non-neuropathic pain.

Dworkin RH, Jensen MP, Gammaitoni AR, Olaleye DO, Galer BS

The journal of pain.. 2007 February 8 (2):118-26. Epub 09/01/2006.

Recommendations for the management of herpes zoster.

Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M, Betts RF, Gershon AA, Haanpaa ML, McKendrick MW, Nurmikko TJ, Oaklander AL, Oxman MN, Pavan-Langston D, Petersen KL, Rowbotham MC, Schmader KE, Stacey BR, Tyring SK, van Wijck AJ, Wallace MS, Wassilew SW, Whitley RJ

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2007 January 144 Suppl 1 :S1-26. Epub 1900 01 01.

An interdisciplinary expert consensus statement on assessment of pain in older persons.

Hadjistavropoulos T, Herr K, Turk DC, Fine PG, Dworkin RH, Helme R, Jackson K, Parmelee PA, Rudy TE, Lynn Beattie B, Chibnall JT, Craig KD, Ferrell B, Ferrell B, Fillingim RB, Gagliese L, Gallagher R, Gibson SJ, Harrison EL, Katz B, Keefe FJ, Lieber SJ, Lussier D, Schmader KE, Tait RC, Weiner DK, Williams J

The Clinical journal of pain.. 2007 January 23 (1 Suppl):S1-43. Epub 1900 01 01.

Developing patient-reported outcome measures for pain clinical trials: IMMPACT recommendations.

Turk DC, Dworkin RH, Burke LB, Gershon R, Rothman M, Scott J, Allen RR, Atkinson JH, Chandler J, Cleeland C, Cowan P, Dimitrova R, Dionne R, Farrar JT, Haythornthwaite JA, Hertz S, Jadad AR, Jensen MP, Kellstein D, Kerns RD, Manning DC, Martin S, Max MB, McDermott MP, McGrath P, Moulin DE, Nurmikko T, Quessy S, Raja S, Rappaport BA, Rauschkolb C, Robinson JP, Royal MA, Simon L, Stauffer JW, Stucki G, Tollett J, von Stein T, Wallace MS, Wernicke J, White RE, Williams AC, Witter J, Wyrwich KW,

Pain.. 2006 December 5125 (3):208-215. Epub 10/25/2006.

Risk factors for chronic pain following breast cancer surgery: a prospective study.

Poleshuck EL, Katz J, Andrus CH, Hogan LA, Jung BF, Kulick DI, Dworkin RH

The journal of pain.. 2006 September 7 (9):626-34. Epub 1900 01 01.

Do pain qualities and spatial characteristics make independent contributions to interference with physical and emotional functioning?

Jensen MP, Dworkin RH, Gammaitoni AR, Olaleye DO, Oleka N, Galer BS

The journal of pain.. 2006 September 7 (9):644-53. Epub 1900 01 01.

Use of the cumulative proportion of responders analysis graph to present pain data over a range of cut-off points: making clinical trial data more understandable.

Farrar JT, Dworkin RH, Max MB

Journal of pain and symptom management.. 2006 April 31 (4):369-77. Epub 1900 01 01.

Skin biopsy and quantitative sensory testing do not predict response to lidocaine patch in painful neuropathies.

Herrmann DN, Pannoni V, Barbano RL, Pennella-Vaughan J, Dworkin RH

Muscle & nerve.. 2006 January 33 (1):42-8. Epub 1900 01 01.

Ion channel targets and treatment efficacy in neuropathic pain.

Markman JD, Dworkin RH

The journal of pain.. 2006 January 7 (1 Suppl 1):S38-47. Epub 1900 01 01.

Post-herpetic neuralgia

Dworkin RH.

Herpes. 2006; 13(suppl 1): 21A-7A.

Placebo response in clinical trials of depression and its implications for research on chronic neuropathic pain.

Dworkin RH, Katz J, Gitlin MJ

Neurology.. 2005 December 2965 (12 Suppl 4):S7-19. Epub 1900 01 01.

Risk factors for acute pain and its persistence following breast cancer surgery.

Katz J, Poleshuck EL, Andrus CH, Hogan LA, Jung BF, Kulick DI, Dworkin RH

Pain.. 2005 December 15119 (1-3):16-25. Epub 11/17/2005.

Psychosocial risk factors for postherpetic neuralgia: a prospective study of patients with herpes zoster.

Katz J, McDermott MP, Cooper EM, Walther RR, Sweeney EW, Dworkin RH

The journal of pain.. 2005 December 6 (12):782-90. Epub 1900 01 01.

Neuropathic pain associated with non-surgical treatment of breast cancer.

Jung BF, Herrmann D, Griggs J, Oaklander AL, Dworkin RH

Pain.. 2005 November 118 (1-2):10-4. Epub 10/04/2005.

A randomized, placebo-controlled trial of bupropion sustained release in chronic low back pain.

Katz J, Pennella-Vaughan J, Hetzel RD, Kanazi GE, Dworkin RH

The journal of pain.. 2005 October 6 (10):656-61. Epub 1900 01 01.

Effects of intradermal foot and forearm capsaicin injections in normal and vulvodynia-afflicted women.

Foster DC, Dworkin RH, Wood RW

Pain.. 2005 September 117 (1-2):128-36. Epub 1900 01 01.

Herpes zoster and the prevention of postherpetic neuralgia: beyond antiviral therapy.

Tenser RB, Dworkin RH

Neurology.. 2005 August 965 (3):349-50. Epub 1900 01 01.

Fibromyalgia from the perspective of neuropathic pain.

Dworkin RH, Fields HL

The Journal of rheumatology. Supplement.. 2005 August 75 :1-5. Epub 1900 01 01.

Pregabalin.

Dworkin RH, Kirkpatrick P

Nature reviews. Drug discovery.. 2005 June 4 (6):455-6. Epub 1900 01 01.

Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial.

Crofford LJ, Rowbotham MC, Mease PJ, Russell IJ, Dworkin RH, Corbin AE, Young JP, LaMoreaux LK, Martin SA, Sharma U,

Arthritis and rheumatism.. 2005 April 52 (4):1264-73. Epub 1900 01 01.

Assessment of pain quality in chronic neuropathic and nociceptive pain clinical trials with the Neuropathic Pain Scale.

Jensen MP, Dworkin RH, Gammaitoni AR, Olaleye DO, Oleka N, Galer BS

The journal of pain.. 2005 February 6 (2):98-106. Epub 1900 01 01.

Contributions of physical and sexual abuse to women's experiences with chronic pelvic pain.

Poleshuck EL, Dworkin RH, Howard FM, Foster DC, Shields CG, Giles DE, Tu X

The Journal of reproductive medicine.. 2005 February 50 (2):91-100. Epub 1900 01 01.

Core outcome measures for chronic pain clinical trials: IMMPACT recommendations.

Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, Kerns RD, Stucki G, Allen RR, Bellamy N, Carr DB, Chandler J, Cowan P, Dionne R, Galer BS, Hertz S, Jadad AR, Kramer LD, Manning DC, Martin S, McCormick CG, McDermott MP, McGrath P, Quessy S, Rappaport BA, Robbins W, Robinson JP, Rothman M, Royal MA, Simon L, Stauffer JW, Stein W, Tollett J, Wernicke J, Witter J,

Pain.. 2005 January 113 (1-2):9-19. Epub 1900 01 01.

An open-label study of the lidocaine patch 5% in painful idiopathic sensory polyneuropathy.

Herrmann DN, Barbano RL, Hart-Gouleau S, Pennella-Vaughan J, Dworkin RH

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2005 6 (5):379-84. Epub 1900 01 01.

Suicidal ideation, plans, and attempts in chronic pain patients: factors associated with increased risk.

Smith MT, Edwards RR, Robinson RC, Dworkin RH

Pain.. 2004 September 111 (1-2):201-8. Epub 1900 01 01.

Acute pain in herpes zoster and its impact on health-related quality of life.

Katz J, Cooper EM, Walther RR, Sweeney EW, Dworkin RH

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2004 August 139 (3):342-8. Epub 07/19/2004.

Effectiveness, tolerability, and impact on quality of life of the 5% lidocaine patch in diabetic polyneuropathy.

Barbano RL, Herrmann DN, Hart-Gouleau S, Pennella-Vaughan J, Lodewick PA, Dworkin RH

Archives of neurology.. 2004 June 61 (6):914-8. Epub 1900 01 01.

Risk factors for postherpetic neuralgia in patients with herpes zoster.

Jung BF, Johnson RW, Griffin DR, Dworkin RH

Neurology.. 2004 May 1162 (9):1545-51. Epub 1900 01 01.

Pharmacologic treatment of chronic pain in the elderly

Dworkin RH, Ginsberg B, Cohen RI.

Clinical geriatrics and annals of long-term care. 2004; 12: S1-10.

What should be the core outcomes in chronic pain clinical trials?

Turk DC, Dworkin RH

Arthritis research & therapy.. 2004 6 (4):151-4. Epub 06/04/2004.

Core outcome domains for chronic pain clinical trials: IMMPACT recommendations.

Turk DC, Dworkin RH, Allen RR, Bellamy N, Brandenburg N, Carr DB, Cleeland C, Dionne R, Farrar JT, Galer BS, Hewitt DJ, Jadad AR, Katz NP, Kramer LD, Manning DC, McCormick CG, McDermott MP, McGrath P, Quessy S, Rappaport BA, Robinson JP, Royal MA, Simon L, Stauffer JW, Stein W, Tollett J, Witter J

Pain.. 2003 December 106 (3):337-345. Epub 1900 01 01.

Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations.

Dworkin RH, Backonja M, Rowbotham MC, Allen RR, Argoff CR, Bennett GJ, Bushnell MC, Farrar JT, Galer BS, Haythornthwaite JA, Hewitt DJ, Loeser JD, Max MB, Saltarelli M, Schmader KE, Stein C, Thompson D, Turk DC, Wallace MS, Watkins LR, Weinstein SM

Archives of neurology.. 2003 November 60 (11):1524-34. Epub 1900 01 01.

Neuropathic pain following breast cancer surgery: proposed classification and research update.

Jung BF, Ahrendt GM, Oaklander AL, Dworkin RH

Pain.. 2003 July 104 (1-2):1-13. Epub 1900 01 01.

Pharmacotherapy of painful diabetic neuropathy.

Barbano R, Hart-Gouleau S, Pennella-Vaughan J, Dworkin RH

Current pain and headache reports.. 2003 June 7 (3):169-77. Epub 1900 01 01.

Pregabalin for the treatment of postherpetic neuralgia: a randomized, placebo-controlled trial.

Dworkin RH, Corbin AE, Young JP, Sharma U, LaMoreaux L, Bockbrader H, Garofalo EA, Poole RM

Neurology.. 2003 April 2260 (8):1274-83. Epub 1900 01 01.

Treatment of herpes zoster and postherpetic neuralgia.

Johnson RW, Dworkin RH

BMJ : British medical journal. 2003 April 5326 (7392):748-50. Epub 1900 01 01.

Treatment and prevention of postherpetic neuralgia.

Dworkin RH, Schmader KE

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2003 April 136 (7):877-82. Epub 03/13/2003.

Congenital insensitivity to pain: an update.

Nagasako EM, Oaklander AL, Dworkin RH

Pain.. 2003 February 101 (3):213-219. Epub 1900 01 01.

Geographic and racial aspects of herpes zoster.

Nagasako EM, Johnson RW, Griffin DR, Elpern DJ, Dworkin RH

Journal of medical virology.. 2003 70 Suppl 1 :S20-3. Epub 1900 01 01.

A randomized, double-blind, placebo-controlled trial of a glycine antagonist in neuropathic pain.

Wallace MS, Rowbotham MC, Katz NP, Dworkin RH, Dotson RM, Galer BS, Rauck RL, Backonja MM, Quessy SN, Meisner PD

Neurology.. 2002 December 1059 (11):1694-700. Epub 1900 01 01.

Lidocaine patch 5% reduces pain intensity and interference with quality of life in patients with postherpetic neuralgia: an effectiveness trial.

Katz NP, Gammaitoni AR, Davis MW, Dworkin RH,

Pain medicine : the official journal of the American Academy of Pain Medicine.. 2002 December 3 (4):324-32. Epub 1900 01 01.

Rash severity in herpes zoster: correlates and relationship to postherpetic neuralgia.

Nagasako EM, Johnson RW, Griffin DR, Dworkin RH

Journal of the American Academy of Dermatology.. 2002 June 46 (6):834-9. Epub 1900 01 01.

An overview of neuropathic pain: syndromes, symptoms, signs, and several mechanisms.

Dworkin RH

The Clinical journal of pain.. 2002 18 (6):343-9. Epub 1900 01 01.

Acute pain in herpes zoster: the famciclovir database project.

Dworkin RH, Nagasako EM, Johnson RW, Griffin DR

Pain.. 2001 October 94 (1):113-119. Epub 1900 01 01.

The management of post-herpetic neuralgia.

Cunningham AL, Dworkin RH

BMJ : British medical journal. 2000 September 30321 (7264):778-9. Epub 1900 01 01.

The role of sympathetic nerve blocks in herpes zoster and postherpetic neuralgia.

Wu CL, Marsh A, Dworkin RH

Pain.. 2000 August 87 (2):121-129. Epub 1900 01 01.

Herpes zoster.

Dworkin RH, Galer BS, Rowbotham MC

The New England journal of medicine.. 2000 July 20343 (3):221-2; author reply 223. Epub 1900 01 01.

Prospects for the prevention of postherpetic neuralgia in herpes zoster patients.

Dworkin RH, Perkins FM, Nagasako EM

The Clinical journal of pain.. 2000 June 16 (2 Suppl):S90-100. Epub 1900 01 01.

Treatment of postherpetic neuralgia: an update.

Kanazi GE, Johnson RW, Dworkin RH

Drugs.. 2000 May 59 (5):1113-26. Epub 1900 01 01.

No alternative to antiviral drugs for acute herpes zoster.

Dworkin RH

Anesthesia and analgesia.. 1999 December 89 (6):1585-6. Epub 1900 01 01.

Toward a model of the pathogenesis of chronic pain.

Dworkin RH, Hetzel RD, Banks SM

Seminars in clinical neuropsychiatry.. 1999 July 4 (3):176-85. Epub 1900 01 01.

Prevention of postherpetic neuralgia.

Dworkin RH

Lancet.. 1999 May 15353 (9165):1636-7. Epub 1900 01 01.

Famciclovir and postherpetic neuralgia

Tyring S, Saltzman RL, Dworkin RH.

Annals of internal medicine. 1999; 131: 712-3.

Guest editorial

Johnson, RW; Dworkin, RH; Breuer J.

European Journal of Pain. 1999; 3: 297-299.

Postherpetic neuralgia: impact of famciclovir, age, rash severity, and acute pain in herpes zoster patients.

Dworkin RH, Boon RJ, Griffin DR, Phung D

The Journal of infectious diseases.. 1998 November 178 Suppl 1 :S76-80. Epub 1900 01 01.

Assessment of pain in herpes zoster: lessons learned from antiviral trials.

Dworkin RH, Carrington D, Cunningham A, Kost RG, Levin MJ, McKendrick MW, Oxman MN, Rentier B, Schmader KE, Tappeiner G, Wassilew SW, Whitley RJ

Antiviral research.. 1997 January 33 (2):73-85. Epub 1900 01 01.

Which individuals with acute pain are most likely to develop a chronic pain syndrome?

Dworkin RH.

Pain forum. 1997; 6: 127-36.

Toward a clearer specification of acute pain risk factors and chronic pain outcomes

Dworkin RH.

Pain forum. 1997; 6: 148-50.

Pain and its assessment in herpes zoster

Dworkin RH.

Antiviral chemistry & chemotherapy. 1997; 8(suppl1): 31-6.

Assessment of pain in herpes zoster

Dworkin RH.

Virus & life: the international journal of clinical virology. 1997; 16: 3-5.

Pain and its persistence in herpes zoster.

Dworkin RH, Portenoy RK

Pain.. 1996 October 67 (2-3):241-51. Epub 1900 01 01.

Does affective blunting in schizophrenia reflect affective deficit or neuromotor dysfunction?

Dworkin RH, Clark SC, Amador XF, Gorman JM

Schizophrenia research.. 1996 July 520 (3):301-6. Epub 1900 01 01.

Racial differences in herpes zoster and age at onset of varicella.

Dworkin RH

The Journal of infectious diseases.. 1996 July 174 (1):239-41. Epub 1900 01 01.

Chronic pain and disease conviction.

Dworkin RH, Cooper EM, Siegfried RN

The Clinical journal of pain.. 1996 June 12 (2):111-7. Epub 1900 01 01.

The dimensions of schizophrenia phenomenology. Not one or two, at least three, perhaps four.

Lenzenweger MF, Dworkin RH

The British journal of psychiatry : the journal of mental science.. 1996 April 168 (4):432-40. Epub 1900 01 01.

Oral acyclovir therapy accelerates pain resolution in patients with herpes zoster: a meta-analysis of placebo-controlled trials.

Wood MJ, Kay R, Dworkin RH, Soong SJ, Whitley RJ

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 1996 February 22 (2):341-7. Epub 1900 01 01.

Pain responsivity in major depression and bipolar disorder.

Dworkin RH, Clark WC, Lipsitz JD

Psychiatry research.. 1995 March 2756 (2):173-81. Epub 1900 01 01.

Predicting schizophrenia.

Dworkin RH, Cornblatt BA

Lancet.. 1995 January 21345 (8943):139-40. Epub 1900 01 01.

Are all those pain ratings necessary?

Dworkin RH, Siegfried RN

Pain.. 1994 August 58 (2):279. Epub 1900 01 01.

Proposed classification of herpes zoster pain.

Dworkin RH, Portenoy RK

Lancet.. 1994 June 25343 (8913):1648. Epub 1900 01 01.

Social competence deficits in adolescents at risk for schizophrenia.

Dworkin RH, Lewis JA, Cornblatt BA, Erlenmeyer-Kimling L

The Journal of nervous and mental disease.. 1994 February 182 (2):103-8. Epub 1900 01 01.

Pain insensitivity in schizophrenia: a neglected phenomenon and some implications.

Dworkin RH

Schizophrenia bulletin.. 1994 20 (2):235-48. Epub 1900 01 01.

Affective deficits and pain insensitivity in schizophrenia.

Dworkin RH, Clark WC, Lipsitz JD, Amador XF, Kaufmann CA, Opler LA, White SR, Gorman JM.

Motivation and emotion. 1993; 17: 245-76.

Wechsler comprehension and picture arrangement subtests and social adjustment

Lipsitz JD, Dworkin RH, Erlenmeyer-Kimling L.

Psychological assessment. 1993; 5: 430-7.

Childhood precursors of affective vs. social deficits in adolescents at risk for schizophrenia.

Dworkin RH, Cornblatt BA, Friedmann R, Kaplansky LM, Lewis JA, Rinaldi A, Shilliday C, Erlenmeyer-Kimling L

Schizophrenia bulletin.. 1993 19 (3):563-77. Epub 1900 01 01.

Childhood attentional dysfunctions predict social deficits in unaffected adults at risk for schizophrenia.

Cornblatt BA, Lenzenweger MF, Dworkin RH, Erlenmeyer-Kimling L

The British journal of psychiatry. Supplement. 1992 October (18):59-64. Epub 1900 01 01.

Simple schizophrenia, negative symptoms, and prefrontal hypodopaminergia.

Dworkin RH, Opler LA

The American journal of psychiatry.. 1992 September 149 (9):1284-5. Epub 1900 01 01.

A high-risk method for studying psychosocial antecedents of chronic pain: the prospective investigation of herpes zoster.

Dworkin RH, Hartstein G, Rosner HL, Walther RR, Sweeney EW, Brand L

Journal of abnormal psychology.. 1992 February 101 (1):200-5. Epub 1900 01 01.

Simple schizophrenia: an investigation of Bleuler's criteria based on the major twin studies of schizophrenia.

Dworkin RH

Acta psychiatrica Scandinavica.. 1992 January 85 (1):61-4. Epub 1900 01 01.

Affective deficits and social deficits in schizophrenia: what's what?

Dworkin RH

Schizophrenia bulletin.. 1992 18 (1):59-64. Epub 1900 01 01.

Social competence and positive and negative symptoms: a longitudinal study of children and adolescents at risk for schizophrenia and affective disorder.

Dworkin RH, Bernstein G, Kaplansky LM, Lipsitz JD, Rinaldi A, Slater SL, Cornblatt BA, Erlenmeyer-Kimling L

The American journal of psychiatry.. 1991 September 148 (9):1182-8. Epub 1900 01 01.

Clinical aspects of depression in chronic pain patients.

Dworkin RH, Gitlin MJ

The Clinical journal of pain.. 1991 June 7 (2):79-94. Epub 1900 01 01.

What do we really know about the psychological origins of chronic pain?

Dworkin RH.

American Pain Society bulletin. 1991; 1(5): 7-11.

Examining the underlying structure of schizophrenic phenomenology: evidence for a three-process model.

Lenzenweger MF, Dworkin RH, Wethington E

Schizophrenia bulletin.. 1991 17 (3):515-24. Epub 1900 01 01.

Compensation in chronic pain patients: cause or consequence?

Dworkin RH

Pain.. 1990 December 43 (3):387-388. Epub 1900 01 01.

Positive and negative symptoms and social competence in adolescents at risk for schizophrenia and affective disorder.

Dworkin RH, Green SR, Small NE, Warner ML, Cornblatt BA, Erlenmeyer-Kimling L

The American journal of psychiatry.. 1990 September 147 (9):1234-6. Epub 1900 01 01.

Models of positive and negative symptoms in schizophrenia: an empirical evaluation of latent structures.

Lenzenweger MF, Dworkin RH, Wethington E

Journal of abnormal psychology.. 1989 February 98 (1):62-70. Epub 1900 01 01.

A multidimensional approach to the genetics of schizophrenia.

Dworkin RH, Lenzenweger MF, Moldin SO, Skillings GF, Levick SE

The American journal of psychiatry.. 1988 September 145 (9):1077-83. Epub 1900 01 01.

Re: Chronic pain, depression, and the dexamethasone suppression test.

Dworkin RH

Pain.. 1988 February 32 (2):257-258. Epub 1900 01 01.

Psychiatric diagnosis and chronic pain: DSM-III-R and beyond.

Dworkin RH, Caligor E

Journal of pain and symptom management.. 1988 3 (2):87-98. Epub 1900 01 01.

Assessment of premorbid social competence in schizophrenia: a methodological note.

Lenzenweger MF, Dworkin RH

Journal of abnormal psychology.. 1987 November 96 (4):367-9. Epub 1900 01 01.

Predicting treatment response in depressed and non-depressed chronic pain patients.

Dworkin RH, Richlin DM, Handlin DS, Brand L

Pain.. 1986 March 24 (3):343-353. Epub 1900 01 01.

Occipital neuralgia: an often missed cause of headache

Rosner HL, Schwartz A, Brand L, Dworkin RH.

Regional anesthesia. 1986; 11: 34-8.

Unraveling the effects of compensation, litigation, and employment on treatment response in chronic pain.

Dworkin RH, Handlin DS, Richlin DM, Brand L, Vannucci C

Pain.. 1985 September 23 (1):49-59. Epub 1900 01 01.

Processing bias: individual differences in the cognition of situations.

Dworkin RH, Goldfinger SH

Journal of personality.. 1985 September 53 (3):480-501. Epub 1900 01 01.

Positive and negative schizophrenic symptoms, attention, and information processing.

Cornblatt BA, Lenzenweger MF, Dworkin RH, Erlenmeyer-Kimling L

Schizophrenia bulletin.. 1985 11 (3):397-408. Epub 1900 01 01.

Symptoms and the genetics of schizophrenia: implications for diagnosis.

Dworkin RH, Lenzenweger MF

The American journal of psychiatry.. 1984 December 141 (12):1541-6. Epub 1900 01 01.

Individual differences in hedonic capacity.

Dworkin RH, Saczynski K

Journal of personality assessment.. 1984 December 48 (6):620-6. Epub 1900 01 01.

Linoleic acid and multiple sclerosis: a reanalysis of three double-blind trials.

Dworkin RH, Bates D, Millar JH, Paty DW

Neurology.. 1984 November 34 (11):1441-5. Epub 1900 01 01.

Traits, consistency, and self-schemata: what do our methods measure?

Burke PA, Kraut RE, Dworkin RH.

Journal of personality and social psychology. 1984; 47: 568-79.

Individual differences in hedonic capacity

Dworkin RH, Saczynski K.

Journal of personality assessment. 1984; 48: 620-6.

DSM III and the genetics of schizophrenia.

Dworkin RH, Lenzenweger MF

The American journal of psychiatry.. 1983 May 140 (5):646. Epub 1900 01 01.

Linoleic acid and multiple sclerosis.

Dworkin RH

Lancet.. 1981 May 231 (8230):1153-4. Epub 1900 01 01.

Genetic and environmental influences on person-situation interactions

Dworkin RH.

Journal of research in personality. 1979; 13(279-93).

An S-R Inventory of Dominance for research on the nature of person-situation interactions.

Dworkin RH, Kihlstrom JF.

Journal of personality. 1978; 46: 43-56.

Genetic influences on cross-situational consistency.

Dworkin RH

Progress in clinical and biological research.. 1978 24A :49-56. Epub 1900 01 01.

Undergraduate MMPI profiles and the longitudinal prediction of adult social outcome.

Dworkin RH, Widom CS

Journal of consulting and clinical psychology.. 1977 August 45 (4):620-4. Epub 1900 01 01.

Genetic influences on the organization and development of personality

Dworkin RH, Burke BW, Maher BA, Gottesman II.

Developmental psychology. 1977; 13: 164-5.

A longitudinal study of the genetics of personality.

Dworkin RH, Burke BW, Maher BA

Journal of personality and social psychology.. 1976 September 34 (3):510-8. Epub 1900 01 01.