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Jacques Robert, Ph.D.

Jacques Robert, Ph.D.

he/him/his

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About Me

Faculty Appointments

Professor - Department of Microbiology and Immunology (SMD)

Chair - Department of Microbiology and Immunology (SMD)

Albert and Phyllis Ritterson Professorship - Department of Microbiology and Immunology (SMD)

Professor - Department of Environmental Medicine (SMD) - Joint

Credentials

Residency & Fellowship

Senior postdoctoral fellow, Department of Microbiology and Immunology University of Rochester School of Medicine and Dentistry 1995 - 1997

Postdoctoral fellow with Dr. Louis Du Pasquier & Member of the Basel Institute for Immunology. 1993 - 1994

Postdoctoral fellow with Dr. Louis Du Pasquier & Member of the Basel Institute for Immunology. 1990 - 1995

Teaching Assistant in Genetics, Cytogenetics and Embryology in the Department of Animal Biology University of Geneva. 1985 - 1990

Predoctoral fellow with Dr. Hans Rudi Kobel, University of Geneva, Department of Animal Biology 1985 - 1990

Education

PhD | Switzerland-Fac Sciences U Geneva. Developmental Biology. 1990

BA | Switzerland-Fac Sciences U Geneva. Biology. 1985

Awards

2019 School of Medicine and Dentistry Trainee Academic Mentoring Award in Basic Science. 2019

Alumni Award Excellence in Postdoctoral Mentoring. 2014

Excellence in Research. 2013

Alumni Award for Excellence in Graduate Education of the University of Rochester Medical Center. 2011

Provost's multidisciplinary award. 2009 - 2010

Excellence in Research Award. 2007

Travel award. 2001

Travel award. 2000

Cum laude graduate. 1990

Research

EVOLUTION OF IMMUNE SURVEILLANCE,
TUMOR AND VIRAL IMMUNITY

The overall goal of our research is to understand the co-evolutionary relationships between the structure of selected molecules (e.g., heat shock proteins [hsps], hsp-receptors [CD91], NK cell receptors [KIR, FcRs], non-classical ...
EVOLUTION OF IMMUNE SURVEILLANCE,
TUMOR AND VIRAL IMMUNITY

The overall goal of our research is to understand the co-evolutionary relationships between the structure of selected molecules (e.g., heat shock proteins [hsps], hsp-receptors [CD91], NK cell receptors [KIR, FcRs], non-classical class Ib molecules [XNCs]) and their functions in innate and adaptive immunity against tumors and viruses using the frog Xenopus laevis as animal model.

One specific research area addresses the postulated dual role of the hsps gp96 and hsp70 in immunity. The comparative tumor-immunity model developed in Xenopus provides an alternative to mice in order to explore the ability of hsps to generate responses against tumors that have down-regulated their MHC class Ia molecules thereby escaping immune surveillance. To better reveal the respective role of classical and non-classical MHC class I genes in immune surveillance and T cell development, we are developing transgenesis strategies to modulate their expression in vivo by RNAi knockdown and induced transgene expression.
A second area concerns phylogenetic history and biological significance several immune receptor gene families (e.g., KIR, FcR-like) that appear to regulate leukocyte functions through integration of inhibitory and activating signals, by genomic and genetic approaches based on the recently fully sequenced genome of the X. laevis sister species Silurana (Xenopus) tropicalis.
A third research area concerns basic comparative and applied studies of viral pathogenesis and immunity in amphibians caused by Poxvirus-like Iridoviruses such as Frog virus 3 (FV3). Because of the threat of emerging wildlife viral diseases on global biodiversity, fundamental research on comparative viral immunity has become crucial. We have established Xenopus as an important experimental model to study the host defense and the pathogenesis of Iridovirus infection, and evaluate the contribution of immunocompromised animals in the dissemination of the diseases. We are also developing a method to knockout (KO) putative virulence genes by site-specific integration of a selectable fluorescent marker into the FV3 genome. Susceptible Xenopus larvae provide an ideal model to evaluate the impact of KOs on in vivo virus load, host mortality and the induction of pro-inflammatory genes.

Xenopus laevis Research Resource for Immunology: The University of Rochester is home to the world's most comprehensive resource specializing in the use of the amphibian Xenopus laevis for immunological research. Several genetically-defined inbred strains and clones are available for study. The facility also maintains and develops research tools such as transgenic animals, monoclonal antibodies, cell lines, DNA libraries and molecular probes. The resource includes a satellite facility devoted to study infectious diseases caused by Iridovirus. The resource is funded by the National Institutes of Health (NIAID).

Publications

Journal Articles

Ingestion of polyethylene terephthalate microplastic water contaminants by Xenopus laevis tadpoles negatively affects their resistance to ranavirus infection and antiviral immunity.

Cai B, De Jesus Andino F, McGrath JL, Romanick SS, Robert J

Environmental pollution.. 2024 June 6356 :124340. Epub 06/06/2024.

The Binding, Infection, and Promoted Growth of by the Ranavirus FV3.

De Jesús Andino F, Davydenko A, Webb RJ, Robert J

Viruses.. 2024 January 2016 (1)Epub 01/20/2024.

Larval T Cells Are Functionally Distinct from Adult T Cells in Xenopus laevis.

Paiola M, McGuire CC, Lopez Ruiz V, De Jesús Andino F, Robert J

ImmunoHorizons.. 2023 October 17 (10):696-707. Epub 1900 01 01.

The amphibian immune system.

Ruiz VL, Robert J

Philosophical transactions of the Royal Society of London. Series B, Biological sciences.. 2023 July 31378 (1882):20220123. Epub 06/12/2023.

Introduction to the special issue Amphibian immunity: stress, disease and ecoimmunology.

Assis VR, Robert J, Titon SCM

Philosophical transactions of the Royal Society of London. Series B, Biological sciences.. 2023 July 31378 (1882):20220117. Epub 06/12/2023.

Advances in the Xenopus immunome: Diversification, expansion, and contraction.

Dimitrakopoulou D, Khwatenge CN, James-Zorn C, Paiola M, Bellin EW, Tian Y, Sundararaj N, Polak EJ, Grayfer L, Barnard D, Ohta Y, Horb M, Sang Y, Robert J

Developmental and comparative immunology.. 2023 May 10 :104734. Epub 05/10/2023.

Environmental endocrine disruptors and amphibian immunity: A bridge between the thyroid hormone axis and T cell development.

McGuire CC, Robert JR

Developmental and comparative immunology.. 2022 December 15 :104617. Epub 12/15/2022.

Amphibians as a model to study the role of immune cell heterogeneity in host and mycobacterial interactions.

Paiola M, Dimitrakopoulou D, Pavelka MS, Robert J

Developmental and comparative immunology.. 2022 November 17 :104594. Epub 11/17/2022.

Evolution and Potential Subfunctionalization of Duplicated -Related Class III Receptor Tyrosine Kinase s and Their Ligands in the Allotetraploid .

Paiola M, Ma S, Robert J

The Journal of immunology : official journal of the American Association of Immunologists.. 2022 September 1209 (5):960-969. Epub 08/05/2022.

Do immune system changes at metamorphosis predict vulnerability to chytridiomycosis? An update.

Humphries JE, Lanctôt CM, Robert J, McCallum HI, Newell DA, Grogan LF

Developmental and comparative immunology.. 2022 August 16 :104510. Epub 08/16/2022.

?? T, NKT, and MAIT Cells During Evolution: Redundancy or Specialized Functions?

Harly C, Robert J, Legoux F, Lantz O

The Journal of immunology : official journal of the American Association of Immunologists.. 2022 July 15209 (2):217-225. Epub 1900 01 01.

Exposure to a mixture of 23 chemicals associated with unconventional oil and gas operations alters immune response to challenge in adult mice.

O'Dell CT, Boule LA, Robert J, Georas SN, Eliseeva S, Lawrence BP

Journal of immunotoxicology.. 2021 December 18 (1):105-117. Epub 1900 01 01.

Virus-Targeted Transcriptomic Analyses Implicate Ranaviral Interaction with Host Interferon Response in Frog Virus 3-Infected Frog Tissues.

Tian Y, De Jesús Andino F, Khwatenge CN, Li J, Robert J, Sang Y

Viruses.. 2021 July 913 (7)Epub 07/09/2021.

Erratum: Assessing Antibody Responses to Pathogens or Model Antigens in by Enzyme-Linked Immunosorbent Assay (ELISA).

Andino FJ, Robert J

Cold Spring Harbor protocols.. 2021 June 12021 (6):pdb.err107715. Epub 06/01/2021.

TLR5 mediated Reactivation of Quiescent Ranavirus FV3 in peritoneal macrophages.

Samanta M, Yim J, Andino FJ, Paiola M, Robert J

Journal of virology.. 2021 April 7 Epub 04/07/2021.

Thyroid Disrupting Chemicals in mixture Perturb Thymocyte Differentiation in Xenopus laevis tadpoles.

McGuire CC, Lawrence BP, Robert J

Toxicological sciences : an official journal of the Society of Toxicology.. 2021 March 3 Epub 03/03/2021.

Emerging Pathogens and a Current-Use Pesticide: Potential Impacts on Eastern Hellbenders.

Cusaac JPW, Carter ED, Woodhams DC, Robert J, Spatz JA, Howard JL, Lillard C, Graham AW, Hill RD, Reinsch S, McGinnity D, Reeves B, Bemis D, Wilkes RP, Sutton WB, Waltzek TB, Hardman RH, Miller DL, Gray MJ

Journal of aquatic animal health.. 2021 February 16 Epub 02/16/2021.

Developing Tadpole as a Comparative Animal Model to Study Pathogenicity.

Lopez A, Shoen C, Cynamon M, Dimitrakopoulou D, Paiola M, Pavelka MS, Robert J

International journal of molecular sciences.. 2021 January 1522 (2)Epub 01/15/2021.

The Immune System and the Antiviral Responses in Chinese Giant Salamander, .

Jiang N, Fan Y, Zhou Y, Meng Y, Liu W, Li Y, Xue M, Robert J, Zeng L

Frontiers in immunology.. 2021 12 :718627. Epub 10/05/2021.

Immunological Aspects of Chytridiomycosis.

Grogan LF, Humphries JE, Robert J, Lanctôt CM, Nock CJ, Newell DA, McCallum HI

Journal of fungi.. 2020 October 196 (4)Epub 10/19/2020.

Experimental Platform Using the Amphibian for Research in Fundamental and Medical Immunology.

Robert J

Cold Spring Harbor protocols.. 2020 May 26 Epub 05/26/2020.

Characterization and expression of macrophage migration inhibitory factor (mif) in Chinese sturgeon (Acipenser sinensis).

Jiang N, Ni Q, Fan Y, Wu S, Zhou Y, Liu W, Si K, Zhang H, Robert J, Zeng L

Fish & shellfish immunology.. 2020 April 25103 :9-16. Epub 04/25/2020.

Developmental exposure to a mixture of unconventional oil and gas chemicals: A review of effects on adult health, behavior, and disease.

Nagel SC, Kassotis CD, Vandenberg LN, Lawrence BP, Robert J, Balise VD

Molecular and cellular endocrinology.. 2020 March 2 :110722. Epub 03/02/2020.

The myeloid lineage is required for the emergence of a regeneration-permissive environment following tail amputation.

Aztekin C, Hiscock TW, Butler R, De Jesús Andino F, Robert J, Gurdon JB, Jullien J

Development.. 2020 February 5147 (3)Epub 02/05/2020.

Broadening and Strengthening Underrepresented Group Inclusion in Immunological Research.

Smolock E, Robert J

Frontiers in immunology.. 2020 11 :465. Epub 03/17/2020.

Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation.

Kim E, Jiang M, Huang H, Zhang Y, Tjota N, Gao X, Robert J, Gilmore N, Gan L, Que J

Developmental cell.. 2019 December 1651 (6):675-683.e4. Epub 12/05/2019.

Distinct Host-Mycobacterial Pathogen Interactions between Resistant Adult and Tolerant Tadpole Life Stages of .

Rhoo KH, Edholm ES, Forzán MJ, Khan A, Waddle AW, Pavelka MS, Robert J

The Journal of immunology : official journal of the American Association of Immunologists.. 2019 October 7 Epub 10/07/2019.

Introduction.

Robert J

Immunological investigations.. 2019 October 48 (7):680-681. Epub 1900 01 01.

Impacts of the MHC class I-like XNC10 and innate-like T cells on tumor tolerance and rejection in the amphibian Xenopus.

Banach M, Edholm ES, Gonzalez X, Benraiss A, Robert J

Carcinogenesis.. 2019 July 2040 (7):924-935. Epub 1900 01 01.

Developmental exposure to chemicals associated with unconventional oil and gas extraction alters immune homeostasis and viral immunity of the amphibian Xenopus.

Robert J, McGuire CC, Nagel S, Lawrence BP, Andino FJ

The Science of the total environment.. 2019 June 25671 :644-654. Epub 03/26/2019.

Evolutionary Underpinnings of Innate-Like T Cell Interactions with Cancer.

Banach M, Robert J

Immunological investigations.. 2019 June 21 :1-22. Epub 06/21/2019.

Adoptive Transfer of Fluorescently Labeled Immune Cells in .

Rhoo KH, Robert J

Cold Spring Harbor protocols.. 2019 May 12019 (5):pdb.prot097592. Epub 05/01/2019.

Critical Role of an MHC Class I-Like/Innate-Like T Cell Immune Surveillance System in Host Defense against Ranavirus (Frog Virus 3) Infection.

Edholm EI, De Jesús Andino F, Yim J, Woo K, Robert J

Viruses.. 2019 April 611 (4)Epub 04/06/2019.

A Xenopus tadpole alternative model to study innate-like T cell-mediated anti-mycobacterial immunity.

Hyoe RK, Robert J

Developmental and comparative immunology.. 2019 March 92 :253-259. Epub 12/04/2018.

Lymphocyte Deficiency Induced by Sublethal Irradiation in .

Rollins-Smith LA, Robert J

Cold Spring Harbor protocols.. 2019 January 22019 (1):pdb.prot097626. Epub 01/02/2019.

Resources: Transgenic, Inbred and Mutant Animals, Training Opportunities, and Web-Based Support.

Horb M, Wlizla M, Abu-Daya A, McNamara S, Gajdasik D, Igawa T, Suzuki A, Ogino H, Noble A, , Robert J, James-Zorn C, Guille M

Frontiers in physiology.. 2019 10 :387. Epub 04/25/2019.

Water Contaminants Associated With Unconventional Oil and Gas Extraction Cause Immunotoxicity to Amphibian Tadpoles.

Robert J, McGuire CC, Kim F, Nagel SC, Price SJ, Lawrence BP, De Jesús Andino F

Toxicological sciences : an official journal of the Society of Toxicology.. 2018 November 1166 (1):39-50. Epub 1900 01 01.

Rag1 and rag2 gene expressions identify lymphopoietic tissues in juvenile and adult Chinese giant salamander (Andrias davidianus).

Jiang N, Fan Y, Zhou Y, Liu W, Robert J, Zeng L

Developmental and comparative immunology.. 2018 October 87 :24-35. Epub 05/22/2018.

RNAi-Mediated Loss of Function of Immune Genes by Transgenesis.

Edholm ES, Robert J

Cold Spring Harbor protocols.. 2018 July 22018 (7)Epub 07/02/2018.

Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice.

Boulé LA, Chapman TJ, Hillman SE, Kassotis CD, O'Dell C, Robert J, Georas SN, Nagel SC, Lawrence BP

Toxicological sciences : an official journal of the Society of Toxicology.. 2018 June 1163 (2):639-654. Epub 1900 01 01.

Distinct MHC class I-like interacting invariant T cell lineage at the forefront of mycobacterial immunity uncovered in .

Edholm ES, Banach M, Hyoe Rhoo K, Pavelka MS, Robert J

Proceedings of the National Academy of Sciences of the United States of America.. 2018 April 24115 (17):E4023-E4031. Epub 04/02/2018.

Frog's DCs have it all in one.

Robert J

European journal of immunology.. 2018 March 48 (3):415-418. Epub 1900 01 01.

Evaluating Blood Cell Populations in Xenopus Using Flow Cytometry and Differential Counts by Cytospin.

Robert J, Edholm ES, De Jesus Andino F

Methods in molecular biology.. 2018 1865 :265-273. Epub 1900 01 01.

Review of the Amphibian Immune Response to Chytridiomycosis, and Future Directions.

Grogan LF, Robert J, Berger L, Skerratt LF, Scheele BC, Castley JG, Newell DA, McCallum HI

Frontiers in immunology.. 2018 9 :2536. Epub 11/09/2018.

Xenopus-FV3 host-pathogen interactions and immune evasion.

Robert J, Edholm ES, Jazz S, Odalys TL, Francisco JA

Virology.. 2017 November 511 :309-319. Epub 06/16/2017.

Collagen-Embedded Tumor Transplantations in Tadpoles.

Banach M, Robert J

Cold Spring Harbor protocols.. 2017 October 32017 (10):pdb.prot097584. Epub 10/03/2017.

Exploring the functions of nonclassical MHC class Ib genes in Xenopus laevis by the CRISPR/Cas9 system.

Banach M, Edholm ES, Robert J

Developmental biology.. 2017 June 15426 (2):261-269. Epub 06/16/2016.

Long term effects of carbaryl exposure on antiviral immune responses in Xenopus laevis.

De Jesús Andino F, Lawrence BP, Robert J

Chemosphere.. 2017 March 170 :169-175. Epub 12/08/2016.

Tumor immunology viewed from alternative animal models-the story.

Banach M, Robert J

Current pathobiology reports.. 2017 March 5 (1):49-56. Epub 01/26/2017.

Evolutionary Aspects of Macrophages Polarization.

Edholm ES, Rhoo KH, Robert J

Results and problems in cell differentiation.. 2017 62 :3-22. Epub 1900 01 01.

Genome evolution in the allotetraploid frog Xenopus laevis.

Session AM, Uno Y, Kwon T, Chapman JA, Toyoda A, Takahashi S, Fukui A, Hikosaka A, Suzuki A, Kondo M, van Heeringen SJ, Quigley I, Heinz S, Ogino H, Ochi H, Hellsten U, Lyons JB, Simakov O, Putnam N, Stites J, Kuroki Y, Tanaka T, Michiue T, Watanabe M, Bogdanovic O, Lister R, Georgiou G, Paranjpe SS, van Kruijsbergen I, Shu S, Carlson J, Kinoshita T, Ohta Y, Mawaribuchi S, Jenkins J, Grimwood J, Schmutz J, Mitros T, Mozaffari SV, Suzuki Y, Haramoto Y, Yamamoto TS, Takagi C, Heald R, Miller K, Haudenschild C, Kitzman J, Nakayama T, Izutsu Y, Robert J, Fortriede J, Burns K, Lotay V, Karimi K, Yasuoka Y, Dichmann DS, Flajnik MF, Houston DW, Shendure J, DuPasquier L, Vize PD, Zorn AM, Ito M, Marcotte EM, Wallingford JB, Ito Y, Asashima M, Ueno N, Matsuda Y, Veenstra GJ, Fujiyama A, Harland RM, Taira M, Rokhsar DS

Nature.. 2016 October 20538 (7625):336-343. Epub 1900 01 01.

Evolution of innate-like T cells and their selection by MHC class I-like molecules.

Edholm ES, Banach M, Robert J

Immunogenetics.. 2016 August 68 (8):525-36. Epub 07/01/2016.

Amphibian macrophage development and antiviral defenses.

Grayfer L, Robert J

Developmental and comparative immunology.. 2016 May 58 :60-7. Epub 12/15/2015.

Preface to the special issue "Hematopoiesis and immunity".

Barreda D, Robert J, Belosevic M

Developmental and comparative immunology.. 2016 May 58 :A1. Epub 02/03/2016.

Frog Virus 3 dissemination in the brain of tadpoles, but not in adult Xenopus, involves blood brain barrier dysfunction.

De Jesús Andino F, Jones L, Maggirwar SB, Robert J

Scientific reports.. 2016 March 26 :22508. Epub 03/02/2016.

Ouro proteins are not essential to tail regression during Xenopus tropicalis metamorphosis.

Nakai Y, Nakajima K, Robert J, Yaoita Y

Genes to cells : devoted to molecular & cellular mechanisms.. 2016 March 21 (3):275-86. Epub 02/05/2016.

Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration.

Haynes-Gimore N, Banach M, Brown E, Dawes R, Edholm ES, Kim M, Robert J

Developmental biology.. 2015 December 15408 (2):205-12. Epub 01/17/2015.

Xenopus: An in vivo model for imaging the inflammatory response following injury and bacterial infection.

Paredes R, Ishibashi S, Borrill R, Robert J, Amaya E

Developmental biology.. 2015 December 15408 (2):213-28. Epub 03/27/2015.

Retention of duplicated ITAM-containing transmembrane signaling subunits in the tetraploid amphibian species Xenopus laevis.

Guselnikov SV, Grayfer L, De JesúsAndino F, Rogozin IB, Robert J, Taranin AV

Developmental and comparative immunology.. 2015 November 53 (1):158-68. Epub 07/11/2015.

Characterization of Frog Virus 3 knockout mutants lacking putative virulence genes.

Andino FJ, Grayfer L, Chen G, Gregory Chinchar V, Edholm ES, Robert J

Virology.. 2015 November 485 :162-70. Epub 08/08/2015.

Distinct functional roles of amphibian (Xenopus laevis) colony-stimulating factor-1- and interleukin-34-derived macrophages.

Grayfer L, Robert J

Journal of leukocyte biology.. 2015 October 98 (4):641-9. Epub 07/01/2015.

Nonclassical MHC-Restricted Invariant V?6 T Cells Are Critical for Efficient Early Innate Antiviral Immunity in the Amphibian Xenopus laevis.

Edholm ES, Grayfer L, De Jesús Andino F, Robert J

The Journal of immunology : official journal of the American Association of Immunologists.. 2015 July 15195 (2):576-86. Epub 06/10/2015.

Prominent amphibian (Xenopus laevis) tadpole type III interferon response to the frog virus 3 ranavirus.

Grayfer L, De Jesús Andino F, Robert J

Journal of virology.. 2015 May 89 (9):5072-82. Epub 02/25/2015.

Evolution of nonclassical MHC-dependent invariant T cells.

Edholm ES, Grayfer L, Robert J

Cellular and molecular life sciences : CMLS.. 2014 December 71 (24):4763-80. Epub 08/14/2014.

Divergent antiviral roles of amphibian (Xenopus laevis) macrophages elicited by colony-stimulating factor-1 and interleukin-34.

Grayfer L, Robert J

Journal of leukocyte biology.. 2014 December 96 (6):1143-53. Epub 09/04/2014.

Negative effects of low dose atrazine exposure on the development of effective immunity to FV3 in Xenopus laevis.

Sifkarovski J, Grayfer L, De Jesús Andino F, Paige Lawrence B, Robert J

Developmental and comparative immunology.. 2014 November 47 (1):52-8. Epub 06/28/2014.

A prominent role for invariant T cells in the amphibian Xenopus laevis tadpoles.

Robert J, Edholm ES

Immunogenetics.. 2014 October 66 (9-10):513-23. Epub 06/05/2014.

A critical role of non-classical MHC in tumor immune evasion in the amphibian Xenopus model.

Haynes-Gilmore N, Banach M, Edholm ES, Lord E, Robert J

Carcinogenesis.. 2014 August 35 (8):1807-13. Epub 04/28/2014.

Environmental dependency of amphibian-ranavirus genotypic interactions: evolutionary perspectives on infectious diseases.

Echaubard P, Leduc J, Pauli B, Chinchar VG, Robert J, Lesbarrères D

Evolutionary applications.. 2014 August 7 (7):723-33. Epub 06/16/2014.

The amphibian (Xenopus laevis) type I interferon response to frog virus 3: new insight into ranavirus pathogenicity.

Grayfer L, De Jesús Andino F, Robert J

Journal of virology.. 2014 May 88 (10):5766-77. Epub 03/12/2014.

Differential transcription of fathead minnow immune-related genes following infection with frog virus 3, an emerging pathogen of ectothermic vertebrates.

Cheng K, Escalon BL, Robert J, Chinchar VG, Garcia-Reyero N

Virology.. 2014 May 456-457 :77-86. Epub 04/01/2014.

Environmental dependency of amphibian–ranavirus genotypic interactions: evolutionary perspectives on infectious diseases

Echaubard, P.; Leduc, J.; Pauli, B.; Chinchar, VG.; Robert, J.; Lesbarrère, L.

Evolutionary Applications. 2014; .

Inflammation-induced reactivation of the ranavirus Frog Virus 3 in asymptomatic Xenopus laevis.

Robert J, Grayfer L, Edholm ES, Ward B, De Jesús Andino F

PloS one.. 2014 9 (11):e112904. Epub 11/12/2014.

Mechanisms of amphibian macrophage development: characterization of the Xenopus laevis colony-stimulating factor-1 receptor.

Grayfer L, Edholm ES, Robert J

The International journal of developmental biology.. 2014 58 (10-12):757-66. Epub 1900 01 01.

Nonclassical MHC class I-dependent invariant T cells are evolutionarily conserved and prominent from early development in amphibians.

Edholm ES, Albertorio Saez LM, Gill AL, Gill SR, Grayfer L, Haynes N, Myers JR, Robert J

Proceedings of the National Academy of Sciences of the United States of America.. 2013 August 27110 (35):14342-7. Epub 08/12/2013.

Effective RNAi-mediated ?2-microglobulin loss of function by transgenesis in Xenopus laevis.

Nedelkovska H, Edholm ES, Haynes N, Robert J

Biology open.. 2013 March 152 (3):335-42. Epub 01/29/2013.

Ranavirus: past, present and future.

Lesbarrères D, Balseiro A, Brunner J, Chinchar VG, Duffus A, Kerby J, Miller DL, Robert J, Schock DM, Waltzek T, Gray MJ

Biology letters.. 2012 August 238 (4):481-3. Epub 11/02/2011.

Immune evasion strategies of ranaviruses and innate immune responses to these emerging pathogens.

Grayfer L, Andino Fde J, Chen G, Chinchar GV, Robert J

Viruses.. 2012 July 4 (7):1075-92. Epub 06/28/2012.

Optimized transgenesis in Xenopus laevis/gilli isogenetic clones for immunological studies.

Nedelkovska H, Robert J

Genesis : the journal of genetics and development.. 2012 March 50 (3):300-6. Epub 12/27/2011.

"Ranaviruses: an emerging threat to ectothermic vertebrates" report of the First International Symposium on Ranaviruses, Minneapolis MN July 8, 2011.

Robert J, Gregory Chinchar V

Developmental and comparative immunology.. 2012 February 36 (2):259-61. Epub 08/26/2011.

Antiviral immunity in amphibians.

Chen G, Robert J

Viruses.. 2011 November 3 (11):2065-2086. Epub 10/31/2011.

Waterborne infectivity of the Ranavirus frog virus 3 in Xenopus laevis.

Robert J, George E, De Jesús Andino F, Chen G

Virology.. 2011 September 1417 (2):410-7. Epub 07/23/2011.

The genus Xenopus as a multispecies model for evolutionary and comparative immunobiology of the 21st century.

Robert J, Cohen N

Developmental and comparative immunology.. 2011 September 35 (9):916-23. Epub 01/28/2011.

Phylogenetic and developmental study of CD4, CD8 ? and ? T cell co-receptor homologs in two amphibian species, Xenopus tropicalis and Xenopus laevis.

Chida AS, Goyos A, Robert J

Developmental and comparative immunology.. 2011 March 35 (3):366-77. Epub 11/21/2010.

Remarkable conservation of distinct nonclassical MHC class I lineages in divergent amphibian species.

Goyos A, Sowa J, Ohta Y, Robert J

The Journal of immunology : official journal of the American Association of Immunologists.. 2011 January 1186 (1):372-81. Epub 11/29/2010.

Comparative in vivo study of gp96 adjuvanticity in the frog Xenopus laevis.

Nedelkovska H, Cruz-Luna T, McPherson P, Robert J

Journal of visualized experiments : JoVE.. 2010 September 16 (43)Epub 09/16/2010.

Comparative study of tumorigenesis and tumor immunity in invertebrates and nonmammalian vertebrates.

Robert J

Developmental and comparative immunology.. 2010 September 34 (9):915-25. Epub 06/02/2010.

Innate immune responses and permissiveness to ranavirus infection of peritoneal leukocytes in the frog Xenopus laevis.

Morales HD, Abramowitz L, Gertz J, Sowa J, Vogel A, Robert J

Journal of virology.. 2010 May 84 (10):4912-22. Epub 03/03/2010.

The genome of the Western clawed frog Xenopus tropicalis.

Hellsten U, Harland RM, Gilchrist MJ, Hendrix D, Jurka J, Kapitonov V, Ovcharenko I, Putnam NH, Shu S, Taher L, Blitz IL, Blumberg B, Dichmann DS, Dubchak I, Amaya E, Detter JC, Fletcher R, Gerhard DS, Goodstein D, Graves T, Grigoriev IV, Grimwood J, Kawashima T, Lindquist E, Lucas SM, Mead PE, Mitros T, Ogino H, Ohta Y, Poliakov AV, Pollet N, Robert J, Salamov A, Sater AK, Schmutz J, Terry A, Vize PD, Warren WC, Wells D, Wills A, Wilson RK, Zimmerman LB, Zorn AM, Grainger R, Grammer T, Khokha MK, Richardson PM, Rokhsar DS

Science.. 2010 April 30328 (5978):633-6. Epub 1900 01 01.

The amphibians Xenopus laevis and Silurana tropicalis possess a family of activating KIR-related Immunoglobulin-like receptors.

Guselnikov SV, Reshetnikova ES, Najakshin AM, Mechetina LV, Robert J, Taranin AV

Developmental and comparative immunology.. 2010 March 34 (3):308-15. Epub 11/17/2009.

Expression profiling the temperature-dependent amphibian response to infection by Batrachochytrium dendrobatidis.

Ribas L, Li MS, Doddington BJ, Robert J, Seidel JA, Kroll JS, Zimmerman LB, Grassly NC, Garner TW, Fisher MC

PloS one.. 2009 December 224 (12):e8408. Epub 12/22/2009.

Genome-wide transcriptional response of Silurana (Xenopus) tropicalis to infection with the deadly chytrid fungus.

Rosenblum EB, Poorten TJ, Settles M, Murdoch GK, Robert J, Maddox N, Eisen MB

PloS one.. 2009 August 44 (8):e6494. Epub 08/04/2009.

Comparative and developmental study of the immune system in Xenopus.

Robert J, Ohta Y

Developmental dynamics : an official publication of the American Association of Anatomists.. 2009 June 238 (6):1249-70. Epub 1900 01 01.

Novel nonclassical MHC class Ib genes associated with CD8 T cell development and thymic tumors.

Goyos A, Ohta Y, Guselnikov S, Robert J

Molecular immunology.. 2009 May 46 (8-9):1775-86. Epub 02/23/2009.

Tumorigenesis and anti-tumor immune responses in Xenopus.

Goyos A, Robert J

Frontiers in bioscience (Landmark edition).. 2009 January 114 (1):167-76. Epub 01/01/2009.

The Xenopus FcR family demonstrates continually high diversification of paired receptors in vertebrate evolution.

Guselnikov SV, Ramanayake T, Erilova AY, Mechetina LV, Najakshin AM, Robert J, Taranin AV

BMC evolutionary biology. 2008 May 168 :148. Epub 05/16/2008.

Phylogenetic conservation of glycoprotein 96 ability to interact with CD91 and facilitate antigen cross-presentation.

Robert J, Ramanayake T, Maniero GD, Morales H, Chida AS

The Journal of immunology : official journal of the American Association of Immunologists.. 2008 March 1180 (5):3176-82. Epub 1900 01 01.

In vivo and in vitro techniques for comparative study of antiviral T-cell responses in the amphibian Xenopus.

Morales H, Robert J

Biological procedures online.. 2008 January 1710 :1-8. Epub 01/17/2008.

In vivo and in vitro techniques for comparative study of antiviral T-cell responses in the amphibian Xenopus.

Morales, H. and J. Robert.

Biol. Proced. Online. 2008; 10:1-7.

The Xenopus FcR-family demonstrates continually high diversification of paired receptors in vertebrate evolution.

Guselnikov S.V., *Ramanayake T, Yerilova, A., Mechetina, L.V., Najakshin A.M., Robert, J., and Taranin A.V.

BMC Evolutionary Biology. 2008; 16:8:148.

Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development.

Marr S, Morales H, Bottaro A, Cooper M, Flajnik M, Robert J

The Journal of immunology : official journal of the American Association of Immunologists.. 2007 November 15179 (10):6783-9. Epub 1900 01 01.

Xenopus laevis: a possible vector of Ranavirus infection?

Robert J, Abramowitz L, Gantress J, Morales HD

Journal of wildlife diseases.. 2007 October 43 (4):645-52. Epub 1900 01 01.

Involvement of nonclassical MHC class Ib molecules in heat shock protein-mediated anti-tumor responses.

Goyos A, Guselnikov S, Chida AS, Sniderhan LF, Maggirwar SB, Nedelkovska H, Robert J

European journal of immunology.. 2007 June 37 (6):1494-501. Epub 1900 01 01.

Characterization of primary and memory CD8 T-cell responses against ranavirus (FV3) in Xenopus laevis.

Morales HD, Robert J

Journal of virology.. 2007 March 81 (5):2240-8. Epub 12/20/2006.

In vivo study of T-cell responses to skin alloantigens in Xenopus using a novel whole-mount immunohistology method.

Ramanayake T, Simon DA, Frelinger JG, Lord EM, Robert J

Transplantation.. 2007 January 2783 (2):159-66. Epub 1900 01 01.

Xenopus laevis: a possible vector of ranavirus infection?

Robert, J., Abramowitz, L., Gantress, J., and Morales, H.

J. Wildlife Diseases. 2007; 43:645-52.

In vivo characterization of primary and secondary anti- ranavirus CD8 T cell responses in Xenopus laevis.

Morales, H.D. and Robert, J.

J. Virol. 2007; .

In vivo study of T-cell responses to skin allo-antigens in Xenopus using a novel whole-mount immunohistology method.

Ramanayake, T., Simon, D., Frelinger, J., Lord, E., and Robert, J.

Transplantation. 2007; 83:159-166.

Involvement of Nonclassical MHC class Ib heat shock protein-mediated anti-tumor responses.

Goyos A, *Guselnikov S, *Nedelkovska H and Robert, J.

Eur. J. Immunol. 2007; 37: 1494-501.

Conservation of IL-6 trans-signaling mechanisms controlling L-selectin adhesion by fever-range thermal stress. Eur. J. Immunol.

Appenheimer 1, M., Girard, R., Chen, O., Wang, WC, Bankert, K., Hardison, J., Bain, M., Ridgley, F., Sarcione, E., Sandra Buitrago, E, Bernd Kaspers, B., Robert, J., Rose-John, S., Baumann, H., and Evans, S.

Eur. J. Immunol. 2007; 37:2856-2867.

Evolutionary analysis of activation-induced cytosine deaminase (AID) in Xenopus ontogeny and during an Immune Response.

Marr, S., Morales, H., Bottaro, A., Cooper, M., Flajnik, M., and Robert, J.

J. Immunol. 2007; 179:6783-6789.

Structural phylogenetic analysis of activation-induced deaminase function.

Ichikawa HT, Sowden MP, Torelli AT, Bachl J, Huang P, Dance GS, Marr SH, Robert J, Wedekind JE, Smith HC, Bottaro A

The Journal of immunology : official journal of the American Association of Immunologists.. 2006 July 1177 (1):355-61. Epub 1900 01 01.

Uncoupling of AID nuclear trafficking and class switch recombination activity revealed by comparative phylogenetic analysis.

Ichikawa, T., Sowden, M., Torelli, A., Huang, P., Dance, G., *Marr, S., Robert, J., Wedekind, J., Smith, H. and Bottaro, A.

J. Immunol. 2006; 177:355-361.

Generation of a long-lasting, protective, and neutralizing antibody response to the ranavirus FV3 by the frog Xenopus.

Maniero GD, Morales H, Gantress J, Robert J

Developmental and comparative immunology.. 2006 30 (7):649-57. Epub 10/04/2005.

Adaptive immunity and histopathology in frog virus 3-infected Xenopus.

Robert J, Morales H, Buck W, Cohen N, Marr S, Gantress J

Virology.. 2005 February 20332 (2):667-75. Epub 1900 01 01.

CD91 up-regulates upon immune stimulation in Xenopus adult but not larval peritoneal leukocytes.

Marr S, Goyos A, Gantress J, Maniero GD, Robert J

Immunogenetics.. 2005 January 56 (10):735-42. Epub 12/08/2004.

Immunotoxicology of amphibians.

Fournier, M., Robert, J., Salo, H., Dautremepuits, C., Brousseau, P.

Rev. Applied Herpetology. 2005; 2: 297-309.

Phylogenetic conservation of gp96-mediated antigen-specific cellular immunity: new evidence from adoptive cell transfer in xenopus.

Maniero GD, Robert J

Transplantation.. 2004 November 2778 (10):1415-21. Epub 1900 01 01.

Anti-tumor MHC class Ia-unrestricted CD8 T cell cytotoxicity elicited by the heat shock protein gp96.

Goyos A, Cohen N, Gantress J, Robert J

European journal of immunology.. 2004 September 34 (9):2449-58. Epub 1900 01 01.

Xenopus as an experimental model for studying evolution of hsp--immune system interactions.

Robert J, Gantress J, Cohen N, Maniero GD

Methods : a companion to Methods in enzymology.. 2004 January 32 (1):42-53. Epub 1900 01 01.

Ontogeny of Xenopus NK cells in the absence of MHC class I antigens.

Horton TL, Stewart R, Cohen N, Rau L, Ritchie P, Watson MD, Robert J, Horton JD

Developmental and comparative immunology.. 2003 September 27 (8):715-26. Epub 1900 01 01.

Signaling FcRgamma and TCRzeta subunit homologs in the amphibian Xenopus laevis.

Guselnikov SV, Bell A, Najakshin AM, Robert J, Taranin AV

Developmental and comparative immunology.. 2003 September 27 (8):727-33. Epub 1900 01 01.

Development and characterization of a model system to study amphibian immune responses to iridoviruses.

Gantress J, Maniero GD, Cohen N, Robert J

Virology.. 2003 July 5311 (2):254-62. Epub 1900 01 01.

Evolution of the immunomodulatory role of the heat shock protein gp96.

Robert J, Cohen N, Maniero GD, Goyos A, Morales H, Gantress J

Cellular and molecular biology.. 2003 March 49 (2):263-75. Epub 1900 01 01.

Immunomodulation by the heat shock protein gp96. In: Immunoproteins and novel mechanisms of immuoregulation. (ed., J. Marchalonis).

Robert, J., Cohen, N., Goyos, A., Maniero, G., Morales, H., and Gantress, J.

Cellular Mol. Biol. 2003; 49: 263-275.

Modulated expression of the endoplasmic reticulum resident gp96 in Xenopus B cells upon bacterial stimulation.

Morales, H., Gantress, J., Cohen, N. and Robert, J.

Cell Stress Chap. 2003; 8: 265-271.

Evolution of heat shock protein and immunity.

Robert J

Developmental and comparative immunology.. 2003 27 (6-7):449-64. Epub 1900 01 01.

Bacterial stimulation upregulates the surface expression of the stress protein gp96 on B cells in the frog Xenopus.

Morales H, Muharemagic A, Gantress J, Cohen N, Robert J

Cell stress & chaperones.. 2003 8 (3):265-71. Epub 1900 01 01.

Identification and characterization of Xenopus CD8+ T cells expressing an NK cell-associated molecule.

Rau L, Gantress J, Bell A, Stewart R, Horton T, Cohen N, Horton J, Robert J

European journal of immunology.. 2002 June 32 (6):1574-83. Epub 1900 01 01.

Minor histocompatibility antigen-specific MHC-restricted CD8 T cell responses elicited by heat shock proteins.

Robert J, Gantress J, Rau L, Bell A, Cohen N

The Journal of immunology : official journal of the American Association of Immunologists.. 2002 February 15168 (4):1697-703. Epub 1900 01 01.

MHC-restricted and -unrestricted CD8 T cells: an evolutionary perspective.

Rau L, Cohen N, Robert J

Transplantation.. 2001 December 1572 (11):1830-5. Epub 1900 01 01.

In vitro thymocyte differentiation in MHC class I-negative Xenopus larvae.

Robert J, Sung M, Cohen N

Developmental and comparative immunology.. 2001 May 25 (4):323-36. Epub 1900 01 01.

Phylogenetic conservation of the molecular and immunological properties of the chaperones gp96 and hsp70.

Robert J, Ménoret A, Basu S, Cohen N, Srivastava PR

European journal of immunology.. 2001 January 31 (1):186-95. Epub 1900 01 01.

Immunological properties of heat shock proteins are phylogenetically conserved.

Robert J, Ménoret A, Srivastava PK, Cohen N

Advances in experimental medicine and biology.. 2001 484 :237-49. Epub 1900 01 01.

B-cell development in the amphibian Xenopus.

Du Pasquier L, Robert J, Courtet M, Mussmann R

Immunological reviews.. 2000 June 175 :201-13. Epub 1900 01 01.

Cell surface expression of the endoplasmic reticular heat shock protein gp96 is phylogenetically conserved.

Robert J, Ménoret A, Cohen N

The Journal of immunology : official journal of the American Association of Immunologists.. 1999 October 15163 (8):4133-9. Epub 1900 01 01.

In vitro differentiation of a CD4/CD8 double-positive equivalent thymocyte subset in adult Xenopus.

Robert J, Cohen N

International immunology.. 1999 April 11 (4):499-508. Epub 1900 01 01.

Evolution of immune surveillance and tumor immunity: studies in Xenopus.

Robert J, Cohen N

Immunological reviews.. 1998 December 166 :231-43. Epub 1900 01 01.

Ontogeny of CTX expression in Xenopus.

Robert, J., and Cohen, N.

Dev. Comp. Immunol. 1998; 12: 605-612.

Ontogeny of CTX expression in xenopus.

Robert J, Cohen N

Developmental and comparative immunology.. 1998 22 (5-6):605-12. Epub 1900 01 01.

Antibody cross-linking of the thymocyte-specific cell surface molecule CTX causes abnormal mitosis and multinucleation of tumor cells.

Robert J, Brown DM, Pasquier LD, Cohen N

Experimental cell research.. 1997 August 25235 (1):227-37. Epub 1900 01 01.

Cross-linking CTX, a novel thymocyte-specific molecule, inhibits the growth of lymphoid tumor cells in Xenopus.

Robert J, Chretien I, Guiet C, Du Pasquier L

Molecular immunology.. 1997 February 34 (2):133-43. Epub 1900 01 01.

Effects of thymectomy and tolerance induction on tumor immunity in adult Xenopus laevis.

Robert J, Guiet C, Cohen N, Du Pasquier L

International journal of cancer.. 1997 January 2770 (3):330-4. Epub 1900 01 01.

Effects of thymectomy and tolerance induction on tumor immunity in adult Xenopus laevis.

Robert, J., Guiet C., Cohen, N., and Du Pasquier L.

Internat. J. Canc. 1997; 70: 330-334.

CTX, a novel molecule specifically expressed on the surface of cortical thymocytes in Xenopus.

Chrétien I, Robert J, Marcuz A, Garcia-Sanz JA, Courtet M, Du Pasquier L

European journal of immunology.. 1996 April 26 (4):780-91. Epub 1900 01 01.

Ontogeny of the alloimmune response against a transplanted tumor in Xenopus laevis.

Robert J, Guiet C, Du Pasquier L

Differentiation; research in biological diversity.. 1995 October 59 (3):135-44. Epub 1900 01 01.

A Xenopus lymphoid tumor cell line with complete Ig genes rearrangements and T-cell characteristics.

Du Pasquier L, Courtet M, Robert J

Molecular immunology.. 1995 June 32 (8):583-93. Epub 1900 01 01.

Lymphoid tumors of Xenopus laevis with different capacities for growth in larvae and adults.

Robert J, Guiet C, Du Pasquier L

Developmental immunology.. 1994 3 (4):297-307. Epub 1900 01 01.

In vitro growth of thymic tumor cell lines from Xenopus.

Du Pasquier L, Robert J

Developmental immunology.. 1992 2 (4):295-307. Epub 1900 01 01.

Differential expression of creatine kinase isozymes during development of Xenopus laevis: an unusual heterodimeric isozyme appears at metamorphosis.

Robert J, Du Pasquier L, Kobel HR

Differentiation; research in biological diversity.. 1991 February 46 (1):23-34. Epub 1900 01 01.

A Xenopus laevis creatine kinase isozyme (CK-III/III) specific for larval striated muscle: cDNA sequence, developmental expression and subcellular immunolocalization.

Robert, J., Barandun, B. and Kobel, H. R.

Genet. Res. Camb. 1991; 58: 35-40.

Purification and characterization of cytoplasmic creatine kinase isozymes of Xenopus laevis.

Robert J, Kobel HR

Biochemical genetics.. 1988 October 26 (9-10):543-55. Epub 1900 01 01.

Etude de la végétation macrophytique de deux étang de la rive sud du lac de Neuchâtel .

Oihénart, C , Perfetta, J. Robert, J., and LaChavanne, J-B.

Châble-Perron et Champ-Pittet. Bull. Soc. Vaud. Sc. Nat. 1988; 79: 23-38.

Etude de la faune du sol en relation avec la culture de carotte de garde.

Robert, J., Fischer, J. and Freuler, J.

Mitt. Schweitz. Ent. Ges. 1985; 58: 413-427.

Les ravageurs de la carotte: description et importance relative de dégâts observés.

Robert, J., Fischer, J. and Freuler, J.

Rev. Suisse Vitic. Arboric. Hortic. 1985; 17: 351-356.

Books

Heat Shock Proteins in the Immune System (2018)

Chapter: An ancestral immune surveillance system in the amphibian Xenopus connecting certain heat shock proteins with classical and nonclassical MHC class I molecules

Authors: Robert J. Banach M., and Edholm E

Publisher: Springer Nature, eBook 2018

Reference Module in Life Sciences: Animal and plant immunology (2017)

Chapter: Humoral Immune Response of Amphibians

Authors: Robert, J.

Publisher: Elsevier Inc., ScienceDirect 2017

Ecology and Evolution of Cancer (2017)

Chapter: Evolutionary perspective of tumorigenesis and anti-tumor immunity provided by comparative studies in the amphibian Xenopus

Authors: Robert J. De Jesús Andino F., Banach M., Park J., Edholm E.

Publisher: Elsevier, Acad Press, London 2017

Macrophages - origin, functions and biointervention (2017)

Chapter: Evolutionary aspects of Macrophages polarization

Authors: Edholm E., Kun Hyoe Rhoo, and Robert J.

Publisher: Springer Nature, eBook 2017

Encyclopedia of Immunobiology (2016)

Chapter: The immune system of amphibians

Authors: Robert, J.

Publisher: Elsevier Ltd., Academic Press, Oxford 2016

Ranaviruses: Lethal Pathogens of Ectothermic Vertebrates (2015)

Chapter: Ranavirus host immunity and immune evasion. In Ranaviruses

Authors: Grayfer L., Edholm E., De Jesús Andino F., Chinchar V.G. and Robert J.

Publisher: Springer 2015

Encyclopedia of Immunobiology (2015)

Chapter: The immune system of amphibians

Authors: Robert J

Publisher: Elsevier 2015

Skin Grafts (2011)

Chapter: Comparative study of skin graft tolerance and rejection in the amphibian Xenopusc

Authors: Nedelkovska H. and Robert, J.

Publisher: Intech, Rijeka, Croatia 2011

Diversity Special Issue: Amphibian Conservation (2010)

Chapter: Emerging ranaviral infectious diseases and amphibian decline

Authors: Robert, J

Publisher: MDPI AG, Basel, Switzerland 2010

The frog Xenopus as a model to study evolutionary, developmental and biomedic (2009)

Chapter: Tumorigenesis and anti-tumor immune response in Xenopus laevis.

Authors: Goyos, A. and Robert J.

Publisher: Frontiers in Bioscience 2009

The frog Xenopus as a model to study evolutionary, developmental and biomedical (2009)

Chapter: Diversity of the FcR- and KIR-related genes in an amphibian Xenopus.

Authors: Guselnikov S.V., *Ramanayake T, Robert, J., and Taranin A.V.

Publisher: Frontiers in Bioscience 2009

Nature Conservation: Global, Environmental and Economic Issues. (2009)

Chapter: Relationships between the state of immune defenses and the increased prevalence of viral and fungal infectious diseases in wild and cultured amphibian populations.

Authors: Morales, H. and J. Robert.

Publisher: Nova Science Publishers, Inc. 2009

Methods: A Companion to Methods in Enzymology (HSP-Immune System Interactions) (2004)

Chapter: Xenopus as an model system to study evolution of HSP-immune system interactions.

Authors: Robert, J., Maniero, G., Cohen, N., and Gantress, J.

Publisher: Academic Press 2004

Manual of Immunological Methods (1996)

Chapter: Xenopus lymphoid tumor cell lines

Authors: Robert, J. and Du Pasquier L.

Publisher: Academic Press 1996

The Biology of Xenopus (1996)

Chapter: The immune system of Xenopus: Special focus on B cell development and immunoglobulin genes.

Authors: Du Pasquier, L., Wilson, M. and Robert, J.

Publisher: Oxford Univ. Press 1996

The Proceeding of The African Amphibian Meeting (1995)

Chapter: The immune system of Xenopus and metamorphosis.

Authors: Robert, J. and Du Pasquier L.

Publisher: Madoqua 1995

Mechanisms of B cell Neoplasia (1993)

Chapter: Characterization of four independent spontaneous lymphoid tumors in Xenopus.

Authors: Robert, J.

Publisher: Roche, Basel, Switzerland. 1993