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Jean-Phillippe Couderc, Ph.D., M.B.A.

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About Me
Credentials
Publications

About Me

Dr. Couderc is a biomedical engineer who obtained his PhD degree with highest honors from the French National Institute of Applied Sciences in Lyon, France in 1997. He was appointed Research Assistant Professor of Medicine in the Cardiology Department of Strong Memorial Hospital, University of Rochester Medical Center, NY. In 2002, he graduated as a Master of Business and Administration from the Simon School of Business of Rochester, NY. He is the Assistant Director of the Heart Research Follow-up Program Laboratory. Dr. Couderc has a position of Chief Technology Officer of iCardiac Technology Inc. He dedicated the past ten years to quantitative electrocardiography focusing on the development of novel techniques for the analysis of the ventricular repolarization from the surface ECG in human and in various animal models. Dr. Couderc is the author or co-author of numerous publications in computational science and engineering, numerical analysis, and computer science applied to electrophysiological signals. He is currently a member of the editorial boards of the Annals of Non-Invasive Electrocardiology, he is holding a SGE position at the Center for Drug Evaluation and Research for the US Food and Drug Administration. Dr. Couderc is principal investigator and a co-investigator in several federal-funded research grants. He has been invited for lectures at universities, laboratories, and industrial research centers in U.S and Europe involving consulting experience with industry and national agencies (NIH and EPA).

Faculty Appointments

Professor - Department of Medicine, Cardiology Heart Research (SMD)

Professor - Department of Electrical & Computer Engineering (RC) - Joint

Credentials

Post-doctoral Training & Residency

Heart Research Follow-up Program, Cardiology Department, University of Rochester Medical Center (NY, USA), Dr. Arthur J. Moss and Dr. Wojciech Zareba. 1997 - 1999

Education

MBA | Simon School. Health Care Management. 2003

PhD | National Institute of Applied Science. Biomedical Engineering. 1997

MS | France - Non-Medical School. Medical Specialties, Oth. 1994

Awards

Rochester Business Journal's 2007 Health Care Achievement Awards 2007

Winner of Frost & Sullivan Technology Innovation of the Year Award in Cardiac Safety Analytics. 2006

Mirowski-Moss Career Development Award, 2-year research funds (2003, Rochester, NY, USA). 2003

Dean's list for academic excellence at the Simon School University of Rochester (2002, Rochester, NY, USA). 2002

Award from the French Ministry of Research, 3-year funds (1993, Lyon, France). 1999

Young Investigators Award from the 23rd Annual Conference of the International Society for Computerized Electrocardiology (1997, Keystone, CO, USA). 1997

Award from the Institute of Electricity and Health, 1-year funds (1996, Paris, France). 1996

Young Investigators Award from the 60th Annual Scientific Meeting of the Japanese Circulation Society (1996, Tokyo, Japan). 1996

Publications

Journal Articles

Heart rate and autonomic biomarkers distinguish convulsive epileptic vs. functional or dissociative seizures.

Ryan JM, Wagner KT, Yerram S, Concannon C, Lin JX, Rooney P, Hanrahan B, Titoff V, Connolly NL, Cranmer R, DeMaria N, Xia X, Mykins B, Erickson S, Couderc JP, Schifitto G, Hughes I, Wang D, Erba G, Auerbach DS

Seizure.. 2023 October 111 :178-186. Epub 08/25/2023.

Monitoring Pulse Rate in the Background Using Front Facing Cameras of Mobile Devices.

Savur C, Dautov R, Bukum K, Xia X, Couderc JP, Tsouri GR

IEEE journal of biomedical and health informatics.. 2023 May 27 (5):2208-2218. Epub 05/04/2023.

Measurements of pulse rate using facial video cameras from smart devices in patients diagnosed with atrial fibrillation.

Barde K, Tsouri G, Page A, Pham T, Lutz M, Hall B, Couderc JP

Journal of electrocardiology.. 2023 78 :58-64. Epub 01/25/2023.

Assessment of facial video-based detection of atrial fibrillation across human complexion.

Couderc JP, Page A, Lutz M, Tsouri GR, Hall B

Cardiovascular digital health journal.. 2022 December 3 (6):305-312. Epub 09/06/2022.

Markers of ventricular repolarization and overall mortality in sleep disordered breathing.

Patel SI, Zareba W, LaFleur B, Couderc JP, Xia X, Woosley R, Patel IY, Combs D, Mashaqi S, Quan SF, Parthasarathy S

Sleep medicine.. 2022 July 95 :9-15. Epub 04/22/2022.

Electrophysiological and ECG Effects of Perhexiline, a Mixed Cardiac Ion Channel Inhibitor, Evaluated in Nonclinical Assays and in Healthy Subjects.

Midei MG, Darpo B, Ayers G, Brown R, Couderc JP, Daly W, Ferber G, Sager PT, Camm AJ

Journal of clinical pharmacology.. 2021 December 61 (12):1606-1617. Epub 07/20/2021.

Erratum: 2021 ISHNE / HRS / EHRA / APHRS Collaborative Statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals: From the International Society for Holter and Noninvasive Electrocardiology / Heart Rhythm Society / European Heart Rhythm Association / Asia Pacific Heart Rhythm Society.

Varma N, Cygankiewicz I, Turakhia M, Heidbuchel H, Hu Y, Chen LY, Couderc JP, Cronin EM, Estep JD, Grieten L, Lane DA, Mehra R, Page A, Passman R, Piccini J, Piotrowicz E, Piotrowicz R, Platonov PG, Ribeiro AL, Rich RE, Russo AM, Slotwiner D, Steinberg JS, Svennberg E

European heart journal. Digital health.. 2021 December 2 (4):727. Epub 11/08/2021.

Diurnal QT analysis in patients with sotalol after cardioversion of atrial fibrillation.

Lenhoff H, Darpö B, Page A, Couderc JP, Tornvall P, Frick M

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2021 July 26 (4):e12834. Epub 02/25/2021.

2021 ISHNE/HRS/EHRA/APHRS collaborative statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals: From the International Society for Holter and Noninvasive Electrocardiology/Heart Rhythm Society/European Heart Rhythm Association/Asia Pacific Heart Rhythm Society.

Journal of arrhythmia.. 2021 April 37 (2):271-319. Epub 01/29/2021.

T-wave and its association with myocardial fibrosis on cardiovascular magnetic resonance examination.

Zareba KM, Truong VT, Mazur W, Smart SM, Xia X, Couderc JP, Raman SV

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2021 March 26 (2):e12819. Epub 12/18/2020.

2021 ISHNE/ HRS/ EHRA/ APHRS collaborative statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals: From the International Society for Holter and Noninvasive Electrocardiology/Heart Rhythm Society/European Heart Rhythm Association/Asia Pacific Heart Rhythm Society.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2021 March 26 (2):e12795. Epub 01/29/2021.

2021 ISHNE / HRS / EHRA / APHRS Collaborative Statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals: From the International Society for Holter and Noninvasive Electrocardiology / Heart Rhythm Society / European Heart Rhythm Association / Asia Pacific Heart Rhythm Society.

European heart journal. Digital health.. 2021 March 2 (1):7-48. Epub 01/29/2021.

2021 ISHNE/HRS/EHRA/APHRS Expert Collaborative Statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals: From the International Society for Holter and Noninvasive Electrocardiology/Heart Rhythm Society/European Heart Rhythm Association/Asia-Pacific Heart Rhythm Society.

Varma N, Cygankiewicz I, Turakhia MP, Heidbuchel H, Hu YF, Chen LY, Couderc JP, Cronin EM, Estep JD, Grieten L, Lane DA, Mehra R, Page A, Passman R, Piccini JP, Piotrowicz E, Piotrowicz R, Platonov PG, Ribeiro AL, Rich RE, Russo AM, Slotwiner D, Steinberg JS, Svennberg E

Circulation. Arrhythmia and electrophysiology.. 2021 February 14 (2):e009204. Epub 02/12/2021.

2021 ISHNE/HRS/EHRA/APHRS Collaborative Statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals: From the International Society for Holter and Noninvasive Electrocardiology/Heart Rhythm Society/European Heart Rhythm Association/Asia Pacific Heart Rhythm Society.

Varma N, Cygankiewicz I, Turakhia MP, Heidbuchel H, Hu Y, Chen LY, Couderc JP, Cronin EM, Estep JD, Grieten L, Lane DA, Mehra R, Page A, Passman R, Piccini JP, Piotrowicz E, Piotrowicz R, Platonov PG, Ribeiro AL, Rich RE, Russo AM, Slotwiner D, Steinberg JS, Svennberg E

Cardiovascular digital health journal.. 2021 February 2 (1):4-54. Epub 01/29/2021.

Autonomic and Cardiac Repolarization Lability in Long QT Syndrome Patients.

DeMaria N, Selmi A, Kashtan S, Xia X, Wang M, Zareba W, Couderc JP, Auerbach DS

Autonomic neuroscience : basic & clinical.. 2020 December 229 :102723. Epub 09/06/2020.

Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster.

Venugopal P, Veyssière H, Couderc JL, Richard G, Vachias C, Mirouse V

BMC developmental biology. 2020 June 1820 (1):10. Epub 06/18/2020.

Evaluation of the Effect of 5 QT-Positive Drugs on the JTpeak Interval - An Analysis of ECGs From the IQ-CSRC Study.

Darpo B, Benson C, Brown R, Dota C, Ferber G, Ferry J, Jarugula V, Keirns J, Ortemann-Renon C, Pham T, Riley S, Sarapa N, Ticktin M, Zareba W, Couderc JP

Journal of clinical pharmacology.. 2020 January 60 (1):125-139. Epub 08/05/2019.

Pacemaker Implantation After Mitral Valve Surgery With Atrial Fibrillation Ablation.

DeRose JJ, Mancini DM, Chang HL, Argenziano M, Dagenais F, Ailawadi G, Perrault LP, Parides MK, Taddei-Peters WC, Mack MJ, Glower DD, Yerokun BA, Atluri P, Mullen JC, Puskas JD, O'Sullivan K, Sledz NM, Tremblay H, Moquete E, Ferket BS, Moskowitz AJ, Iribarne A, Gelijns AC, O'Gara PT, Blackstone EH, Gillinov AM,

Journal of the American College of Cardiology.. 2019 May 2173 (19):2427-2435. Epub 1900 01 01.

Low lead one ratio predicts clinical outcomes in left bundle branch block.

Loring Z, Atwater BD, Xia X, Axelsson J, Klem I, Nijveldt R, Schelbert EB, Couderc JP, Strauss DG, Ugander M, Wieslander B

Journal of cardiovascular electrophysiology.. 2019 May 30 (5):709-716. Epub 02/19/2019.

Biatrial maze procedure versus pulmonary vein isolation for atrial fibrillation during mitral valve surgery: New analytical approaches and end points.

Blackstone EH, Chang HL, Rajeswaran J, Parides MK, Ishwaran H, Li L, Ehrlinger J, Gelijns AC, Moskowitz AJ, Argenziano M, DeRose JJ, Couderc JP, Balda D, Dagenais F, Mack MJ, Ailawadi G, Smith PK, Acker MA, O'Gara PT, Gillinov AM

The Journal of thoracic and cardiovascular surgery.. 2019 January 157 (1):234-243.e9. Epub 07/27/2018.

Prenatal and recent methylmercury exposure and heart rate variability in young adults: the Seychelles Child Development Study.

Zareba W, Thurston SW, Zareba G, Couderc JP, Evans K, Xia J, Watson GE, Strain JJ, McSorley E, Yeates A, Mulhern M, Shamlaye CF, Bovet P, van Wijngaarden E, Davidson PW, Myers GJ

Neurotoxicology and teratology.. 2019 74 :106810. Epub 05/23/2019.

Genes Involved in Drosophila melanogaster Ovarian Function Are Highly Conserved Throughout Evolution.

Elis S, Desmarchais A, Cardona E, Fouchecourt S, Dalbies-Tran R, Nguyen T, Thermes V, Maillard V, Papillier P, Uzbekova S, Bobe J, Couderc JL, Monget P

Genome biology and evolution.. 2018 October 110 (10):2629-2642. Epub 10/01/2018.

Baseline adverse electrical remodeling and the risk for ventricular arrhythmia in Cardiac Resynchronization Therapy Recipients (MADIT CRT).

Biton Y, Ng CY, Xia X, Baman JR, Couderc JP, Moss AJ, Kutyifa V, McNitt S, Polonsky B, Zareba W

Journal of cardiovascular electrophysiology.. 2018 July 29 (7):1017-1023. Epub 06/12/2018.

Abnormal Repolarization Duration During Everyday Emotional Arousal in Long QT Syndrome and Coronary Artery Disease.

Lane RD, Reis HT, Hsu CH, Kern KB, Couderc JP, Moss AJ, Zareba W

The American journal of medicine.. 2018 May 131 (5):565-572.e2. Epub 01/05/2018.

Ventricular Electrical Delay Measured From Body Surface ECGs Is Associated With Cardiac Resynchronization Therapy Response in Left Bundle Branch Block Patients From the MADIT-CRT Trial (Multicenter Automatic Defibrillator Implantation-Cardiac Resynchronization Therapy).

Plesinger F, Jurak P, Halamek J, Nejedly P, Leinveber P, Viscor I, Vondra V, McNitt S, Polonsky B, Moss AJ, Zareba W, Couderc JP

Circulation. Arrhythmia and electrophysiology.. 2018 May 11 (5):e005719. Epub 04/26/2018.

Arthur J. Moss, MD-A giant who changed cardiology.

Zareba W, Kutyifa V, Couderc JP

Heart rhythm.. 2018 May 15 (5):639-640. Epub 1900 01 01.

Semi-automated QRS score as a predictor of survival in CRT treated patients with strict left bundle branch block.

Reitan C, Chaudhry U, Atwater B, Jacobsson J, Couderc JP, Xia X, Carlson J, Platonov PG, Borgquist R

Journal of electrocardiology.. 2018 51 (2):282-287. Epub 11/15/2017.

Challenges in implementing and obtaining acceptance for J-Tpeak assessment as the clinical component of CiPA.

Darpo B, Couderc JP

Journal of pharmacological and toxicological methods.. 2018 93 :75-79. Epub 06/04/2018.

The 43rd International Society for Computerized Electrocardiology ECG initiative for the automated detection of strict left bundle branch block.

Zusterzeel R, Vicente J, Ochoa-Jimenez R, Zhu J, Couderc JP, Akinnagbe-Zusterzeel E, Strauss DG

Journal of electrocardiology.. 2018 51 (6S):S25-S30. Epub 08/01/2018.

The multiple arrhythmia dataset evaluation database (M.A.D.A.E.).

DeCamilla J, Xia X, Wang M, Wade J, Mykins B, Zareba W, Couderc JP

Journal of electrocardiology.. 2018 51 (6S):S106-S112. Epub 08/09/2018.

The ability of the electrocardiogram in left bundle branch block to detect myocardial scar determined by cardiovascular magnetic resonance.

Wieslander B, Xia X, Jablonowski R, Axelsson J, Klem I, Nijveldt R, Maynard C, Schelbert EB, Sörensson P, Sigfridsson A, Chaudhry U, Platonov PG, Borgquist R, Engblom H, Couderc JP, Strauss DG, Atwater BD, Ugander M

Journal of electrocardiology.. 2018 51 (5):779-786. Epub 05/30/2018.

Detection of atrial fibrillation using an earlobe photoplethysmographic sensor.

Conroy T, Hernandez Guzman J, Hall B, Tsouri G, Couderc JP

Physiological measurement.. 2017 September 2638 (10):1906-1918. Epub 09/26/2017.

Evaluation of the ECG based Selvester scoring method to estimate myocardial scar burden and predict clinical outcome in patients with left bundle branch block, with comparison to late gadolinium enhancement CMR imaging.

Chaudhry U, Platonov PG, Jablonowski R, Couderc JP, Engblom H, Xia X, Wieslander B, Atwater BD, Strauss DG, Van der Pals J, Ugander M, Carlsson M, Borgquist R

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2017 September 22 (5)Epub 03/01/2017.

Prediction of sudden and non-sudden cardiac death in post-infarction patients with reduced left ventricular ejection fraction by periodic repolarization dynamics: MADIT-II substudy.

Rizas KD, McNitt S, Hamm W, Massberg S, Kääb S, Zareba W, Couderc JP, Bauer A

European heart journal.. 2017 July 1438 (27):2110-2118. Epub 1900 01 01.

T-Wave Morphology in LQTS Patients: Challenges and Hopes.

Couderc JP, Zareba W

JACC. Clinical electrophysiology.. 2017 April 3 (4):382-383. Epub 04/17/2017.

Validation of an automatic diagnosis of strict left bundle branch block criteria using 12-lead electrocardiograms.

Xia X, Ruwald AC, Ruwald MH, Ugoeke N, Szepietowska B, Kutyifa V, Aktas MK, Thomsen PE, Zareba W, Moss AJ, Couderc JP

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2017 March 22 (2)Epub 08/30/2016.

The QT Scale: A Weight Scale Measuring the QTc Interval.

Couderc JP, Beshaw C, Niu X, Serrano-Finetti E, Casas O, Pallas-Areny R, Rosero S, Zareba W

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2017 January 22 (1)Epub 07/15/2016.

Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization.

Couderc JL, Richard G, Vachias C, Mirouse V

PloS one.. 2017 12 (8):e0182279. Epub 08/02/2017.

Population-based beat-to-beat QT analysis from Holter recordings in the long QT syndrome.

Page A, McNitt S, Xia X, Zareba W, Couderc JP

Journal of electrocardiology.. 2017 50 (6):787-791. Epub 08/10/2017.

JT interval: What does this interval mean?

Zareba W, McNitt S, Polonsky S, Couderc JP

Journal of electrocardiology.. 2017 50 (6):748-751. Epub 08/03/2017.

An evaluation of multiple algorithms for the measurement of the heart rate corrected JTpeak interval.

Couderc JP, Ma S, Page A, Besaw C, Xia J, Chiu WB, de Bie J, Vicente J, Vaglio M, Badilini F, Babaeizadeh S, Chien CS, Baumert M

Journal of electrocardiology.. 2017 50 (6):769-775. Epub 09/01/2017.

Computational cardiology and risk stratification for sudden cardiac death: one of the grand challenges for cardiology in the 21st century.

Hill AP, Perry MD, Abi-Gerges N, Couderc JP, Fermini B, Hancox JC, Knollmann BC, Mirams GR, Skinner J, Zareba W, Vandenberg JI

The Journal of physiology.. 2016 December 1594 (23):6893-6908. Epub 06/09/2016.

Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes.

Mann SA, Imtiaz M, Winbo A, Rydberg A, Perry MD, Couderc JP, Polonsky B, McNitt S, Zareba W, Hill AP, Vandenberg JI

Journal of molecular and cellular cardiology.. 2016 November 100 :25-34. Epub 09/20/2016.

T-wave morphology can distinguish healthy controls from LQTS patients.

Immanuel SA, Sadrieh A, Baumert M, Couderc JP, Zareba W, Hill AP, Vandenberg JI

Physiological measurement.. 2016 September 37 (9):1456-73. Epub 08/11/2016.

QT interval variability in body surface ECG: measurement, physiological basis, and clinical value: position statement and consensus guidance endorsed by the European Heart Rhythm Association jointly with the ESC Working Group on Cardiac Cellular Electrophysiology.

Baumert M, Porta A, Vos MA, Malik M, Couderc JP, Laguna P, Piccirillo G, Smith GL, Tereshchenko LG, Volders PG

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.. 2016 June 18 (6):925-44. Epub 01/27/2016.

Automatic QRS Selvester scoring system in patients with left bundle branch block.

Xia X, Wieslander B, Strauss DG, Wagner GS, Zareba W, Moss AJ, Couderc JP

"QT clock" to improve detection of QT prolongation in long QT syndrome patients.

Page A, Aktas MK, Soyata T, Zareba W, Couderc JP

Heart rhythm.. 2016 January 13 (1):190-8. Epub 08/31/2015.

A pilot randomized trial teaching mindfulness-based stress reduction to traumatized youth in foster care.

Jee SH, Couderc JP, Swanson D, Gallegos A, Hilliard C, Blumkin A, Cunningham K, Heinert S

Complementary therapies in clinical practice.. 2015 August 21 (3):201-9. Epub 06/20/2015.

Cloud-based privacy-preserving remote ECG monitoring and surveillance.

Page A, Kocabas O, Soyata T, Aktas M, Couderc JP

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2015 July 20 (4):328-37. Epub 12/16/2014.

Surgical Ablation of Atrial Fibrillation during Mitral-Valve Surgery.

Gillinov AM, Gelijns AC, Parides MK, DeRose JJ, Moskowitz AJ, Voisine P, Ailawadi G, Bouchard D, Smith PK, Mack MJ, Acker MA, Mullen JC, Rose EA, Chang HL, Puskas JD, Couderc JP, Gardner TJ, Varghese R, Horvath KA, Bolling SF, Michler RE, Geller NL, Ascheim DD, Miller MA, Bagiella E, Moquete EG, Williams P, Taddei-Peters WC, O'Gara PT, Blackstone EH, Argenziano M,

The New England journal of medicine.. 2015 April 9372 (15):1399-409. Epub 03/16/2015.

Surgical ablation of atrial fibrillation during mitral-valve surgery.

The New England journal of medicine.. 2015 April 9372 (15):1399-409. Epub 03/16/2015.

Detection of atrial fibrillation using contactless facial video monitoring.

Couderc JP, Kyal S, Mestha LK, Xu B, Peterson DR, Xia X, Hall B

Heart rhythm.. 2015 January 12 (1):195-201. Epub 08/29/2014.

Selvester scoring in patients with strict LBBB using the QUARESS software.

Xia X, Chaudhry U, Wieslander B, Borgquist R, Wagner GS, Strauss DG, Platonov P, Ugander M, Couderc JP

Journal of electrocardiology.. 2015 48 (5):763-8. Epub 06/05/2015.

Method for classifying cardiac arrhythmias using photoplethysmography.

Polania LF, Mestha LK, Huang DT, Couderc JP

Annual International Conference of the IEEE Engineering in Medicine and Biology Society.. 2015 2015 :6574-7. Epub 1900 01 01.

Prognostic Significance of Heart Rate Variability Among Patients Treated With Cardiac Resynchronization Therapy: MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy).

Sherazi S, Kutyifa V, McNitt S, Aktas MK, Couderc JP, Peterson B, Bloch Thomsen PE, Kautzner J, Moss AJ, Zareba W

JACC. Clinical electrophysiology.. 2015 1 (1-2):74-80. Epub 04/20/2015.

Prognostic value of average T-wave alternans and QT variability for cardiac events in MADIT-II patients.

Monasterio V, Martínez JP, Laguna P, McNitt S, Polonsky S, Moss AJ, Haigney M, Zareba W, Couderc JP

Journal of electrocardiology.. 2013 46 (6):480-6. Epub 09/09/2013.

Measure of the QT-RR dynamic coupling in patients with the long QT syndrome.

Halamek J, Couderc JP, Jurak P, Vondra V, Zareba W, Viscor I, Leinveber M Sc P

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2012 October 17 (4):323-30. Epub 08/13/2012.

QT variability index changes with severity of cardiovascular autonomic neuropathy.

Khandoker A, Imam M, Couderc J, Palaniswami M, Jelinek H

IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society.. 2012 September 16 (5):900-6. Epub 08/24/2012.

Predictive value of beat-to-beat QT variability index across the continuum of left ventricular dysfunction: competing risks of noncardiac or cardiovascular death and sudden or nonsudden cardiac death.

Tereshchenko LG, Cygankiewicz I, McNitt S, Vazquez R, Bayes-Genis A, Han L, Sur S, Couderc JP, Berger RD, Bayes de Luna A, Zareba W

Circulation. Arrhythmia and electrophysiology.. 2012 August 15 (4):719-27. Epub 06/23/2012.

The Telemetric and Holter ECG Warehouse (THEW): the first three years of development and research.

Couderc JP

Journal of electrocardiology.. 2012 45 (6):677-83. Epub 09/28/2012.

The use of beat-to-beat electrocardiogram analysis to distinguish QT/QTc interval changes caused by moxifloxacin from those caused by vardenafil.

Fossa AA, Langdon G, Couderc JP, Zhou M, Darpo B, Wilson F, Wallis R, Davis JD

Clinical pharmacology and therapeutics.. 2011 September 90 (3):449-54. Epub 08/03/2011.

T-wave morphology abnormalities in benign, potent, and arrhythmogenic I(kr) inhibition.

Couderc JP, Xia X, Peterson DR, McNitt S, Zhao H, Polonsky S, Zareba W

Heart rhythm.. 2011 July 8 (7):1036-43. Epub 02/09/2011.

Highly automated QT measurement techniques in 7 thorough QT studies implemented under ICH E14 guidelines.

Couderc JP, Garnett C, Li M, Handzel R, McNitt S, Xia X, Polonsky S, Zareba W

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2011 January 16 (1):13-24. Epub 1900 01 01.

Improving the precision of QT measurements.

Darpo B, Fossa AA, Couderc JP, Zhou M, Schreyer A, Ticktin M, Zapesochny A

Cardiology journal.. 2011 18 (4):401-10. Epub 1900 01 01.

Changes in deceleration capacity of heart rate and heart rate variability induced by ambient air pollution in individuals with coronary artery disease.

Schneider A, Hampel R, Ibald-Mulli A, Zareba W, Schmidt G, Schneider R, Ruckerl R, Couderc JP, Mykins B, Oberdorster G, Wolke G, Pitz M, Wichmann HE, Peters A

Particle and fibre toxicology.. 2010 October 77 :29. Epub 10/07/2010.

Static and Dynamic Electrocardiographic Patterns Preceding Torsades de Pointes in the Acquired and Congenital Long QT Syndrome.

Couderc J, Xia J, Xu X, Kaab S, Hinteeser M, Zareba W

Computing in cardiology. 2010 September 2637 :357-360. Epub 1900 01 01.

A Comparison of IIR and Wavelet Filtering for Noise Reduction of the ECG.

Sørensen J, Johannesen L, Grove U, Lundhus K, Couderc JP, Graff C

Computing in cardiology. 2010 September 2637 :489-492. Epub 1900 01 01.

A scientific repository to support the research and development of technologies related to quantitative electrocardiography: the Telemetric and Holter ECG Warehouse (THEW).

Couderc JP

Cardiology journal.. 2010 17 (4):416-9. Epub 1900 01 01.

Short and long QT syndromes: does QT length really matter?

Couderc JP, Lopes CM

Journal of electrocardiology.. 2010 43 (5):396-9. Epub 1900 01 01.

A unique digital electrocardiographic repository for the development of quantitative electrocardiography and cardiac safety: the Telemetric and Holter ECG Warehouse (THEW).

Couderc JP

Journal of electrocardiology.. 2010 43 (6):595-600. Epub 09/21/2010.

The telemetric and Holter ECG warehouse initiative (THEW): a data repository for the design, implementation and validation of ECG-related technologies.

Couderc JP

Annual International Conference of the IEEE Engineering in Medicine and Biology Society.. 2010 2010 :6252-5. Epub 1900 01 01.

A Wavelet-Based Algorithm for Delineation and Classification of Wave Patterns in Continuous Holter ECG Recordings.

Johannesen L, Grove U, Sørensen J, Schmidt M, Couderc JP, Graff C

Computing in cardiology. 2010 37 (5738139):979-982. Epub 1900 01 01.

Analysis of T-wave Amplitude Adaptation to Heart Rate Using RR-binning of Long-Term ECG Recordings.

Johannesen L, Grove U, Sørensen J, Schmidt M, Graff C, Couderc JP

Computing in cardiology. 2010 37 :369-372. Epub 1900 01 01.

Measurement and regulation of cardiac ventricular repolarization: from the QT interval to repolarization morphology.

Couderc JP

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences.. 2009 April 13367 (1892):1283-99. Epub 1900 01 01.

Electrophysiological effects of late percutaneous coronary intervention for infarct-related coronary artery occlusion: the Occluded Artery Trial-Electrophysiological Mechanisms (OAT-EP).

Rashba EJ, Lamas GA, Couderc JP, Hollist SM, Dzavik V, Ruzyllo W, Fridrich V, Buller CE, Forman SA, Kufera JA, Carvalho AC, Hochman JS,

Circulation.. 2009 February 17119 (6):779-87. Epub 02/02/2009.

ECG parameters and exposure to carbon ultrafine particles in young healthy subjects.

Zareba W, Couderc JP, Oberdörster G, Chalupa D, Cox C, Huang LS, Peters A, Utell MJ, Frampton MW

Inhalation toxicology.. 2009 February 21 (3):223-33. Epub 1900 01 01.

Baseline values and sotalol-induced changes of ventricular repolarization duration, heterogeneity, and instability in patients with a history of drug-induced torsades de pointes.

Couderc JP, Kaab S, Hinterseer M, McNitt S, Xia X, Fossa A, Beckmann BM, Polonsky S, Zareba W

Journal of clinical pharmacology.. 2009 January 49 (1):6-16. Epub 10/28/2008.

An update on QT measurement and interpretation methodologies.

Couderc JP, Zareba W

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2009 January 14 Suppl 1 (Suppl 1):S1-2. Epub 1900 01 01.

Cardiac regulation and electrocardiographic factors contributing to the measurement of repolarization variability.

Couderc JP

Journal of electrocardiology.. 2009 42 (6):494-9. Epub 08/28/2009.

A quantitative assessment of T-wave morphology in LQT1, LQT2, and healthy individuals based on Holter recording technology.

Vaglio M, Couderc JP, McNitt S, Xia X, Moss AJ, Zareba W

Heart rhythm.. 2008 January 5 (1):11-8. Epub 08/28/2007.

Improving the detection of subtle I(Kr)-inhibition: assessing electrocardiographic abnormalities of repolarization induced by moxifloxacin.

Couderc JP, McNitt S, Hyrien O, Vaglio M, Xia X, Polonsky S, Moss AJ, Zareba W

Drug safety.. 2008 31 (3):249-60. Epub 1900 01 01.

Investigating the effect of sotalol on the repolarization intervals in healthy young individuals.

Couderc JP, Zhou M, Sarapa N, Zareba W

Journal of electrocardiology.. 2008 41 (6):595-602. Epub 09/17/2008.

Impaired T-amplitude adaptation to heart rate characterizes I(Kr) inhibition in the congenital and acquired forms of the long QT syndrome.

Couderc JP, Vaglio M, Xia X, McNitt S, Wicker P, Sarapa N, Moss AJ, Zareba W

Journal of cardiovascular electrophysiology.. 2007 December 18 (12):1299-305. Epub 10/04/2007.

Analyses of dynamic beat-to-beat QT-TQ interval (ECG restitution) changes in humans under normal sinus rhythm and prior to an event of torsades de pointes during QT prolongation caused by sotalol.

Fossa AA, Wisialowski T, Crimin K, Wolfgang E, Couderc JP, Hinterseer M, Kaab S, Zareba W, Badilini F, Sarapa N

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2007 October 12 (4):338-48. Epub 1900 01 01.

Repolarization variability in the risk stratification of MADIT II patients.

Couderc JP, Zareba W, McNitt S, Maison-Blanche P, Moss AJ

Effects of on-road highway aerosol exposures on autonomic responses in aged, spontaneously hypertensive rats.

Elder A, Couderc JP, Gelein R, Eberly S, Cox C, Xia X, Zareba W, Hopke P, Watts W, Kittelson D, Frampton M, Utell M, Oberdörster G

Inhalation toxicology.. 2007 January 19 (1):1-12. Epub 1900 01 01.

Impaired T-amplitude Adaptation to Heart-Rate Characterizes IKr-Inhibition in the Congenital and Acquired Forms of the Long QT Syndrome.

Couderc, J. P.; Vaglio, M.; Xia, X.; McNitt, S.; Wicker, P.; Sarapa, N.; Moss, A.J.; Zareba, W.

J Cardiovasc Electrocardiol. 2007; 18: 1299-1305.

Analyses of dynamic beat-to-beat QT-TQ interval (ECG restitution) changes in humans under normal sinus rhythm and prior to an event of torsades de pointes during QT prolongation caused by sotalol

Fossa, A; Wisialowski, T; Crimin, K ; Wolfgang, E; Couderc, JP;Hinterseer, M; Kaab,S; Zareba, W; Badilini,F; Sarapa,N.

Ann. Non-invasiv. Electrocardiol. 2007; 12(4): 338-348.

Repolarization morphology in adult LQT2 carriers with borderline prolonged QTc interval.

Couderc JP, McNitt S, Xia J, Zareba W, Moss AJ

Heart rhythm.. 2006 December 3 (12):1460-6. Epub 08/10/2006.

QT interval prolongation and beyond.

Couderc JP

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2006 October 11 (4):287-8. Epub 1900 01 01.

Preserved heart rate variability identifies low-risk patients with nonischemic dilated cardiomyopathy: results from the DEFINITE trial.

Rashba EJ, Estes NA, Wang P, Schaechter A, Howard A, Zareba W, Couderc JP, Perkiomaki J, Levine J, Kadish A

Heart rhythm.. 2006 March 3 (3):281-6. Epub 1900 01 01.

Electrocardiographic method for identifying drug-induced repolarization abnormalities associated with a reduction of the rapidly activating delayed rectifier potassium current.

Couderc JP, Vaglio M, Xia X, McNitt S, Hyrien O

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society.. 2006 2006 :4010-5. Epub 1900 01 01.

Repolarization changes induced by air pollution in ischemic heart disease patients.

Henneberger A, Zareba W, Ibald-Mulli A, Rückerl R, Cyrys J, Couderc JP, Mykins B, Woelke G, Wichmann HE, Peters A

Environmental health perspectives.. 2005 April 113 (4):440-6. Epub 1900 01 01.

Assessment of the stability of the individual-based correction of QT interval for heart rate.

Couderc JP, Xiaojuan X, Zareba W, Moss AJ

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2005 January 10 (1):25-34. Epub 1900 01 01.

Electrocardiographic identification of drug-induced QT prolongation: assessment by different recording and measurement methods.

Sarapa N, Morganroth J, Couderc JP, Francom SF, Darpo B, Fleishaker JC, McEnroe JD, Chen WT, Zareba W, Moss AJ

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2004 January 9 (1):48-57. Epub 1900 01 01.

Temporal complexity of repolarization and mortality in patients with implantable cardioverter defibrillators.

Perkiomaki JS, Couderc JP, Daubert JP, Zareba W

Pacing and clinical electrophysiology : PACE.. 2003 October 26 (10):1931-6. Epub 1900 01 01.

Identification of sotalol-induced changes in repolarization with T wave area-based repolarization duration parameters.

Couderc JP, Zareba W, Moss AJ, Sarapa N, Morganroth J, Darpo B

Journal of electrocardiology.. 2003 36 Suppl :115-20. Epub 1900 01 01.

Automatic Analysis of the Repolarization Segment

Couderc,J.P.; Zareba,W.; Moss,A.J.;.

J.Int.Soc.Bioelectromagnetism. 2002; 4(Int Soc Biomagnetism): 43-45.

Altered atrial, atrioventricular, and ventricular conduction in patients with the long QT syndrome caused by the DeltaKPQ SCN5A sodium channel gene mutation.

Zareba W, Sattari MN, Rosero S, Couderc JP, Moss AJ

The American journal of cardiology.. 2001 December 188 (11):1311-4. Epub 1900 01 01.

Heart rate variability in patients with congenital long QT syndrome.

Perkiömäki JS, Zareba W, Couderc JP, Moss AJ

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2001 October 6 (4):298-304. Epub 1900 01 01.

ISHNE guidelines for electrocardiographic evaluation of drug-related QT prolongation and other alterations in ventricular repolarization: task force summary. A report of the Task Force of the International Society for Holter and Noninvasive Electrocardiology (ISHNE), Committee on Ventricular Repolarization.

Moss AJ, Zareba W, Benhorin J, Couderc JP, Kennedy H, Locati-Heilbron E, Maison-Blanche P

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.. 2001 October 6 (4):333-41. Epub 1900 01 01.

Cardiovascular effects of air pollution: what to measure in ECG?

Zareba W, Nomura A, Couderc JP

Environmental health perspectives.. 2001 August 109 Suppl 4 (Suppl 4):533-8. Epub 1900 01 01.

Fractal correlation properties of heart rate dynamics and adverse events in patients with implantable cardioverter-defibrillators.

Perkiömäki JS, Zareba W, Daubert JP, Couderc JP, Corsello A, Kremer K

The American journal of cardiology.. 2001 July 188 (1):17-22. Epub 1900 01 01.

Comparability of nonlinear measures of heart rate variability between long- and short-term electrocardiographic recordings.

Perkiömäki JS, Zareba W, Kalaria VG, Couderc J, Huikuri HV, Moss AJ

The American journal of cardiology.. 2001 April 187 (7):905-8. Epub 1900 01 01.

Identification of post-myocardial infarction patients prone to ventricular tachycardia using time-frequency analysis of QRS and ST segments.

Couderc JP, Chevalier P, Fayn J, Rubel P, Touboul P

Automatic detection of spatial and temporal heterogeneity of repolarization.

Zareba,W.; Couderc,J.P.; Moss A.J.;.

Ann.Noninvasive.Electrocardiol. 2000; : 1-3.

Beat-to-Beat repolarization variability in LQTS patients with the SCN5A sodium channel gene mutation.

Couderc JP, Zareba W, Burattini L, Moss AJ

Pacing and clinical electrophysiology : PACE.. 1999 November 22 (11):1581-92. Epub 1900 01 01.

Beat-to-beat repolarization variability in LQTS patients with the SCN5A sodium channel gene mutation.

Couderc JP; Zareba W; Konecki JA; et al.

Pacing & Clinical Electrophysiology. 1999; 2: 1581-1592.

Contribution of the Wavelet Analysis to the Noninvasive Electrocardiology

Couderc JP; Zareba W.

Ann Noninvasive Electrocardiol. 1998; 3(1): 54-62.

ECG features of microvolt T-wave alternans in coronary artery disease and long QT syndrome patients.

Burattini L, Zareba W, Rashba EJ, Couderc JP, Konecki J, Moss AJ

Journal of electrocardiology.. 1998 31 Suppl :114-20. Epub 1900 01 01.

Beat-to-beat repolarization variability in amplitude and duration in LQTS patients with the SCN5A sodium channel gene mutation.

Couderc JP, Zareba W, Burattini L, Konecki JA, Moss AJ

Journal of electrocardiology.. 1998 31 Suppl :134. Epub 1900 01 01.

Are serial Holter QT, late potential, and wavelet measurement clinically useful?

Rubel P, Hamidi S, Behlouli H, Couderc JP, Fayn J, Forlini MC, Maison-Blanche P, Miquel M, Coumel P, Touboul P

Journal of electrocardiology.. 1996 29 Suppl :52-61. Epub 1900 01 01.

Stratification of time-frequency abnormalities in the signal-averaged high-resolution ECG in postinfarction patients with and without ventricular tachycardia and congenital long QT syndrome.

Couderc JP, Fareh S, Chevalier P, Fayn J, Kirkorian G, Rubel P, Touboul P

Journal of electrocardiology.. 1996 29 Suppl :180-8. Epub 1900 01 01.

Wavelet analysis of high-resolution ECGs in post-infarction patients: role of the basic wavelet and of the analyzed lead.

Morlet D, Couderc JP, Touboul P, Rubel P

International journal of bio-medical computing. 1995 June 39 (3):311-25. Epub 1900 01 01.

Books

Cardiac Safety of Non-Cardiac Drugs: Practical Guidelines for Clinical Research (2005)

Chapter: Assessment of ventricular repolarization from body-surface ECGs in humans.

Authors: Couderc JP, Zareba W.

Publisher: Humana Press, Totowa, New Jersey 2005

Noninvasive Electrocardiology in Clinical Practice. (2001)

Chapter: T wave alternans and T wave variability: noninvasive indices of vulnerability to ventricular tachyarrhythmias.

Authors: Zareba W, Couderc JP, Burratini L.

Publisher: Futura Publishing Company Inc., Armonk, New-York 2001

. Noninvasive Electrocardiology. Clinical Aspects of Holter Monitoring. (1999)

Chapter: Spectral analysis of high-resolution ECGs.

Authors: Rubel P, Couderc JP, Morlet D

Publisher: WB Saunders Company Ltd, London 1999