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Sabine Monique Brouxhon, M.D.

Sabine Monique Brouxhon, M.D.


About Me

Faculty Appointments

Adjunct Associate Professor - Department of Neuroscience (SMD)


Post-doctoral Training & Residency

University of Rochester, Post Doctoral Fellow Department of Dermatology

University of Rochester, Research Fellow Department of Dermatology 2000 - 2001

University of Rochester, Emergency Medicine 1998 - 2002


MD | Univ Rochester Sch Med/Dent. Medicine. 1998

BS | Pace University-Westchester. Biology/Chemistry. 1991

BS | Canada - Non-Medical School. Psychology. 1989


Scholorship Recipient. 2007

Emergency Medicine Career Development Award. 2002 - 2003

EMF Creativity and Innovation in Emergency Medicine Grant. 2001 - 2002

Resident Research Fellowship Award. 2000 - 2001


Journal Articles

Peripheral blood mononuclear cell infiltration and neuroinflammation in the HexB-/- mouse model of neurodegeneration.

Kyrkanides S, Miller AW, Miller JN, Tallents RH, Brouxhon SM, Olschowka ME, O'Banion MK, Olschowka JA

Journal of neuroimmunology.. 2008 October 15203 (1):50-7. Epub 1900 01 01.

Effects of continuous-wave (670-nm) red light on wound healing.

Erdle BJ, Brouxhon S, Kaplan M, Vanbuskirk J, Pentland AP

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].. 2008 March 34 (3):320-5. Epub 12/20/2007.

Spinal IL1 in arthritis and joint pain

Fiorentino, P.; Tallents, R.; Miller, JH.; Brouxhon, S.; O'Banion, MK.; Puzas, J.; Kyrkanides, S.

Arthritis & Rheumatism. 2008; .

Sequential down-regulation of E-cadherin with squamous cell carcinoma progression: loss of E-cadherin via a prostaglandin E2-EP2 dependent posttranslational mechanism.

Brouxhon S, Kyrkanides S, O'Banion MK, Johnson R, Pearce DA, Centola GM, Miller JN, McGrath KH, Erdle B, Scott G, Schneider S, VanBuskirk J, Pentland AP

Cancer research.. 2007 August 1567 (16):7654-64. Epub 1900 01 01.

Intraperitoneal inoculation of Sandhoff mouse neonates with an HIV-1 based lentiviral vector exacerbates the attendant neuroinflammation and disease phenotype.

Kyrkanides, S.; Miller, JH.; Tallents, R.; Brouxhon, S.; Centola, G.; Olschowka, J.

Neuroimmunol. 2007; 188(1-2): 39-47.

Deletion of prostaglandin E2 EP2 receptor protects against Ultraviolet (UV) induced carcinogenesis, but increases tumor aggressiveness.

Brouxhon, S.; Konger, R.; Vanbuskirk, J.; McGrath, K.H.; Tanck, C.; Sheu, T.; Almudevar, A.; Breyer, R.; Scott, G.; Pentland, A.P.

JID. 2006; .

b-hexosaminidase lentiviral vectors: Transfer into the CNS via systemic administration.

Kyrkanides, S.; Miller, JH.; Brouxhon, S.; Olshowka, J.; Federoff, H.

Molecular Brain Research. 2005; 113: 286-298.

The growth inhibitory prostaglandin E2 EP3 receptor stimulates release of ceramide, sn-1,2-diacylglycerol and exhibits both positive and negative effects on keratinocyte differentiation.

Konger, R.L.; Brouxhon, S.; Partillo, S.; Thompson, A.; VanBuskirk, J.; Pentland, A.P.

Exp Dermatol. 2005; 12: 914-922.

Abnormal PGE(2) regulation of monocyte TNF-alpha levels in trauma patients parallels development of a more macrophage-like phenotype.

Laudanski K, De A, Brouxhon S, Kyrkanides S, Miller-Graziano C

Shock.. 2004 September 22 (3):204-12. Epub 1900 01 01.

Cyclooxygenase-1 deletion enhances apoptosis but does not protect against ultraviolet light-induced tumors.

Pentland AP, Scott G, VanBuskirk J, Tanck C, LaRossa G, Brouxhon S

Cancer research.. 2004 August 1564 (16):5587-91. Epub 1900 01 01.

Effects of interleukin-2 on the expression of corticotropin-releasing hormone in nerves and lymphoid cells in secondary lymphoid organs from the Fischer 344 rat.

Bellinger DL, Felten DL, Lorton D, Brouxhon S

Journal of neuroimmunology.. 2001 September 3119 (1):37-50. Epub 1900 01 01.

Strain differences in the expression of corticotropin-releasing hormone immunoreactivity in nerves that supply the spleen and thymus.

Bellinger DL, Brouxhon SM, Lubahn C, Tran L, Kang JI, Felten DL, Lorton D

Neuroimmunomodulation.. 2001 9 (2):78-87. Epub 1900 01 01.

Localization of corticotropin-releasing factor in primary and secondary lymphoid organs of the rat.

Brouxhon, SM.; Prasad, AV.; Joseph, SA.; Felten, DL.; Bellinger, DL.

Brain, Behavior, & Immunity. 1998; 12(2): 107-122.

Vasoactive intestinal polypeptide (VIP) innervation of rat spleen, thymus, and lymph nodes.

Bellinger DL, Lorton D, Horn L, Brouxhon S, Felten SY, Felten DL

Peptides.. 1997 18 (8):1139-49. Epub 1900 01 01.

The significance of vasoactive intestinal polypeptide (VIP) in immunomodulation.

Bellinger DL, Lorton D, Brouxhon S, Felten S, Felten DL

Advances in neuroimmunology. 1996 6 (1):5-27. Epub 1900 01 01.