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Mark B. Taubman, M.D.

Mark B. Taubman, M.D.

Cardiology

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About Me

Dr. Taubman is certified by the American Board of Internal Medicine in both Internal Medicine and Cardiovascular Disease.

Dr. Taubman received his medical degree at the New York University School of Medicine. He completed his residency in Internal Medicine at Brigham & Women's Hospital in Bo...
Dr. Taubman is certified by the American Board of Internal Medicine in both Internal Medicine and Cardiovascular Disease.

Dr. Taubman received his medical degree at the New York University School of Medicine. He completed his residency in Internal Medicine at Brigham & Women's Hospital in Boston, Massachusetts, and completed fellowships in Cardiology at Brigham & Women's Hospital and Boston Children's Hospital. Prior to coming to the University of Rochester, Dr. Taubman served as Professor of Medicine at the Mount Sinai School of Medicine in New York City.

Professional Background

Dr. Taubman is CEO of the Medical Center, Dean of the School of Medicine and Dentistry, and Senior Vice President for Health Sciences at the University of Rochester. He received his M.D. degree from New York University and completed his training in medicine and cardiology at the Brigham and Women's...
Dr. Taubman is CEO of the Medical Center, Dean of the School of Medicine and Dentistry, and Senior Vice President for Health Sciences at the University of Rochester. He received his M.D. degree from New York University and completed his training in medicine and cardiology at the Brigham and Women's Hospital and Harvard Medical School. He has served on the faculties of Mt. Sinai School of Medicine in New York, Children's Hospital Medical Center and Harvard Medical School in Boston, Massachusetts. Dr. Taubman was previously the Charles E. Dewey Professor and Chairman of Medicine (2007-2010) and Chief of the Cardiology Division (2003-2009) at the University of Rochester. In addition he was Director of the Aab Cardiovascular Research Institute (2005-2007) and Director of the Center for Cellular and Molecular Cardiology (2003-2005). Dr. Taubman is a member of the American Heart Association, the American Society of Hypertension, the Association of University Cardiologists, and the Association of American Medical Colleges. He is a Fellow, American College of Cardiology and Fellow, American College of Physicians. He is the former Editor-in-Chief, Arteriosclerosis, Thrombosis, and Vascular Biology.

Dr. Taubman is an international authority in vascular biology with research interests in tissue factor biology and chemokines. He has published widely – more than 120 articles, chapters, and books.

Certified Specialties

Cardiovascular Disease - American Board of Internal Medicine

Internal Medicine - American Board of Internal Medicine

Faculty Appointments

Professor - Department of Medicine, Cardiology (SMD)

Dean, School of Medicine & Dentistry - Dean's Office, SMD (SMD)

CEO, University of Rochester Medical Center - Office of VP for Health Sciences (URMC)

Credentials

Residency & Fellowship

Fellowship, Research, Children's Hospital of Boston. 1984 - 1989

Fellowship, Cardiovascular Disease, Brigham & Womens Hospital. 1981 - 1983

Residency, Internal Medicine, Brigham & Womens Hospital. 1979 - 1981

Internship, Internal Medicine, Brigham & Womens Hospital. 1978 - 1979

Education

MD | New York University School of Medicine. 1978

Awards

Alpha Omega Alpha 2004

Special Recognition Award, Council on Arteriosclerosis,
Thrombosis, and Vascular Biology
2002

Distinguished Research Award, Department of Medicine,
Mount Sinai School Of Medicine
1996

Irma T. Hirschl Award
"Isolation and characterization of genes regulating blood vessel growth
1991 - 1995

NIH Clinical Investigator Award
"Vascular smooth muscle cDNA contractile protein clones"
Boston Children's Hospital, Boston, MA
1984 - 1989

NIH Institutional Training Grant for Cardiovascular Research
Brigham & Women's Hospital, Boston, MA
1983 - 1984

NIH Training Grant
Medical Scientist Training Program,
New York University School of Medicine, New York, NY
1972 - 1978

Research

Dr. Mark B. Taubman received his BA in Biochemistry from Columbia University and his M.D. from New York University School of Medicine. He subsequently completed a Residency in Internal Medicine and a Fellowship in Cardiovascular Diseases at the Brigham and Women's Hospital of Harvard Medical School...
Dr. Mark B. Taubman received his BA in Biochemistry from Columbia University and his M.D. from New York University School of Medicine. He subsequently completed a Residency in Internal Medicine and a Fellowship in Cardiovascular Diseases at the Brigham and Women's Hospital of Harvard Medical School. After 5 years on the faculty of the Brigham and Women's Hospital, he joined the Mount Sinai School of Medicine in New York, where he developed a well-funded research program in vascular biology, focusing on the regulation of pro-inflammatory and pro-thrombotic molecules in smooth muscle cells and in the arterial wall. In addition to his research program, Dr. Taubman was the Director of the Cardiology Fellowship, the Principal Investigator of an NIH training grant in Molecular Cardiology, and the Director of the Medical Scientist Training Program (MD-PhD). In 2003, Dr. Taubman moved to the University of Rochester as Chief of the Cardiology Division, and the Director of the Cardiovascular Research Institute. In 2007, Dr. Taubman was appointed Chairman of the Department of Medicine. Dr. Taubman has served as a charter member of the AICS study section of the NHLBI and the Chairman of the Research Committee of the National American Heart Association (AHA). In 2006, in recognition of his contributions to vascular biology, he received the Russell Ross Memorial Award of the Arteriosclerosis, Thrombosis, and Vascular Biology Council of the AHA. In 2007, Dr. Taubman was named Editor-in-Chief of the AHA journal, Arteriosclerosis, Thrombosis, and Vascular Biology.

Patents

Treatment of Pulmonary Hypertension Using An Agent that Inhibits a Tissue Factor Pathway

Issue date: October 22, 2013

Patent #: 8,563,511

Country: United States

Inventors: Mark B Taubman, R. James White

Treatment of Pulmonary Hypertension Using an Agent that Inhibits a Tissue Factor Pathway

Issue date: July 15, 2015

Patent #: 1799243

Country: Europe

Inventors: Mark B Taubman, R. James White

Treatment of Pulmonary Hypertension Using An Agent that Inhibits a Tissue Factor Pathway

Issue date: July 15, 2015

Patent #: FR1799243

Country: France

Inventors: Mark B Taubman, R. James White

Treatment of Pulmonary Hypertension Using An Agent that Inhibits a Tissue Factor Pathway

Issue date: July 15, 2015

Patent #: DE1799243

Country: Germany

Inventors: Mark B Taubman, R. James White

Treatment of Pulmonary Hypertension Using An Agent that Inhibits a Tissue Factor Pathway

Issue date: July 15, 2015

Patent #: GB1799243

Country: United Kingdom

Inventors: Mark B Taubman, R. James White

Publications

Journal Articles

Platelets and megakaryocytes contain functional nuclear factor-kappaB.

Spinelli SL, Casey AE, Pollock SJ, Gertz JM, McMillan DH, Narasipura SD, Mody NA, King MR, Maggirwar SB, Francis CW, Taubman MB, Blumberg N, Phipps RP

Arteriosclerosis, thrombosis, and vascular biology.. 2010 March 30 (3):591-8. Epub 12/30/2009.

The platelet as an immune cell-CD40 ligand and transfusion immunomodulation.

Blumberg N, Spinelli SL, Francis CW, Taubman MB, Phipps RP

Immunologic research.. 2009 December 45 (2-3):251-60. Epub 01/29/2009.

Foxp3 regulates megakaryopoiesis and platelet function.

Bernard JJ, Seweryniak KE, Koniski AD, Spinelli SL, Blumberg N, Francis CW, Taubman MB, Palis J, Phipps RP

Arteriosclerosis, thrombosis, and vascular biology.. 2009 November 29 (11):1874-82. Epub 08/06/2009.

Tissue factor and VEGF expression in prostate carcinoma: a tissue microarray study.

Yao JL, Ryan CK, Francis CW, Kohli M, Taubman MB, Khorana AA

Cancer investigation.. 2009 May 27 (4):430-4. Epub 1900 01 01.

Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury.

Wang L, Miller C, Swarthout RF, Rao M, Mackman N, Taubman MB

Blood.. 2009 January 15113 (3):705-13. Epub 10/17/2008.

15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes.

O'Brien JJ, Spinelli SL, Tober J, Blumberg N, Francis CW, Taubman MB, Palis J, Seweryniak KE, Gertz JM, Phipps RP

Blood.. 2008 November 15112 (10):4051-60. Epub 08/28/2008.

Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.

Ray DM, Spinelli SL, Pollock SJ, Murant TI, O'Brien JJ, Blumberg N, Francis CW, Taubman MB, Phipps RP

Thrombosis and haemostasis.. 2008 January 99 (1):86-95. Epub 1900 01 01.

The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects.

Spinelli SL, O'Brien JJ, Bancos S, Lehmann GM, Springer DL, Blumberg N, Francis CW, Taubman MB, Phipps RP

PPAR research. 2008 2008 :328172. Epub 1900 01 01.

Inhibition of MCP-1/CCR2 signaling does not inhibit intimal proliferation in a mouse aortic transplant model.

Alexis JD, Pyo RT, Chereshnev I, Katz J, Rollins BJ, Charo IF, Taubman MB

Journal of vascular research.. 2008 45 (6):538-46. Epub 05/07/2008.

The role of smooth muscle derived tissue factor in mediating thrombosis and arterial injury.

Taubman MB, Wang L, Miller C

Thrombosis research.. 2008 122 Suppl 1 :S78-81. Epub 1900 01 01.

Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension.

White RJ, Meoli DF, Swarthout RF, Kallop DY, Galaria II, Harvey JL, Miller CM, Blaxall BC, Hall CM, Pierce RA, Cool CD, Taubman MB

American journal of physiology. Lung cellular and molecular physiology.. 2007 September 293 (3):L583-90. Epub 06/22/2007.

Tissue factor expression, angiogenesis, and thrombosis in pancreatic cancer.

Khorana AA, Ahrendt SA, Ryan CK, Francis CW, Hruban RH, Hu YC, Hostetter G, Harvey J, Taubman MB

Clinical cancer research : an official journal of the American Association for Cancer Research.. 2007 May 1513 (10):2870-5. Epub 1900 01 01.

Effects of pioglitazone on fasting and postprandial levels of lipid and hemostatic variables in overweight non-diabetic patients with coronary artery disease.

Mieszczanska H, Kaba NK, Francis CW, Gerich JE, Dodis R, Schwarz KQ, Phipps RP, Smith BH, Lee M, Messing S, Taubman MB

Journal of thrombosis and haemostasis : JTH.. 2007 May 5 (5):942-9. Epub 1900 01 01.

EGLN3 prolyl hydroxylase regulates skeletal muscle differentiation and myogenin protein stability.

Fu J, Menzies K, Freeman RS, Taubman MB

The Journal of biological chemistry.. 2007 April 27282 (17):12410-8. Epub 03/06/2007.

A novel role for the glucocorticoid receptor in the regulation of monocyte chemoattractant protein-1 mRNA stability.

Dhawan L, Liu B, Blaxall BC, Taubman MB

The Journal of biological chemistry.. 2007 April 6282 (14):10146-52. Epub 02/02/2007.

The platelet as a therapeutic target for treating vascular diseases and the role of eicosanoid and synthetic PPARgamma ligands.

O'Brien JJ, Ray DM, Spinelli SL, Blumberg N, Taubman MB, Francis CW, Wittlin SD, Phipps RP

Prostaglandins & other lipid mediators.. 2007 January 82 (1-4):68-76. Epub 07/10/2006.

PDGF-BB enhances monocyte chemoattractant protein-1 mRNA stability in smooth muscle cells by downregulating ribonuclease activity.

Liu B, Poon M, Taubman MB

Journal of molecular and cellular cardiology.. 2006 July 41 (1):160-9. Epub 05/23/2006.

Tissue factor is induced in a rodent model of severe pulmonary hypertension characterized by neointimal lesions typical of human disease.

White RJ, Galaria II, Harvey J, Blaxall BC, Cool CD, Taubman MB

Chest.. 2005 December 128 (6 Suppl):612S-613S. Epub 1900 01 01.

EGFL7 is a chemoattractant for endothelial cells and is up-regulated in angiogenesis and arterial injury.

Campagnolo L, Leahy A, Chitnis S, Koschnick S, Fitch MJ, Fallon JT, Loskutoff D, Taubman MB, Stuhlmann H

The American journal of pathology.. 2005 July 167 (1):275-84. Epub 1900 01 01.

Chemokines in the pathogenesis of vascular disease.

Charo IF, Taubman MB

Circulation research.. 2004 October 2995 (9):858-66. Epub 1900 01 01.

Mice deficient in tissue factor demonstrate attenuated intimal hyperplasia in response to vascular injury and decreased smooth muscle cell migration.

Pyo RT, Sato Y, Mackman N, Taubman MB

Thrombosis and haemostasis.. 2004 September 92 (3):451-8. Epub 1900 01 01.

CCL11 (Eotaxin) induces CCR3-dependent smooth muscle cell migration.

Kodali RB, Kim WJ, Galaria II, Miller C, Schecter AD, Lira SA, Taubman MB

Arteriosclerosis, thrombosis, and vascular biology.. 2004 July 24 (7):1211-6. Epub 05/06/2004.

MCP-1-dependent signaling in CCR2(-/-) aortic smooth muscle cells.

Schecter AD, Berman AB, Yi L, Ma H, Daly CM, Soejima K, Rollins BJ, Charo IF, Taubman MB

Journal of leukocyte biology.. 2004 June 75 (6):1079-85. Epub 03/12/2004.

Inhibition of intimal hyperplasia in transgenic mice conditionally expressing the chemokine-binding protein M3.

Pyo R, Jensen KK, Wiekowski MT, Manfra D, Alcami A, Taubman MB, Lira SA

The American journal of pathology.. 2004 June 164 (6):2289-97. Epub 1900 01 01.

Regulation of the SM-20 prolyl hydroxylase gene in smooth muscle cells.

Menzies K, Liu B, Kim WJ, Moschella MC, Taubman MB

Biochemical and biophysical research communications.. 2004 May 7317 (3):801-10. Epub 1900 01 01.

Chemokine receptor-8 (CCR8) mediates human vascular smooth muscle cell chemotaxis and metalloproteinase-2 secretion.

Haque NS, Fallon JT, Pan JJ, Taubman MB, Harpel PC

Blood.. 2004 February 15103 (4):1296-304. Epub 10/23/2003.

MCP-1 deficiency is associated with reduced intimal hyperplasia after arterial injury.

Kim WJ, Chereshnev I, Gazdoiu M, Fallon JT, Rollins BJ, Taubman MB

Biochemical and biophysical research communications.. 2003 October 24310 (3):936-42. Epub 1900 01 01.

Chemokine receptors in vascular smooth muscle.

Schecter AD, Berman AB, Taubman MB

Microcirculation : the official journal of the Microcirculatory Society, Inc.. 2003 June 10 (3-4):265-72. Epub 1900 01 01.

Angiotensin II: a vasoactive hormone with ever-increasing biological roles.

Taubman MB

Circulation research.. 2003 January 1092 (1):9-11. Epub 1900 01 01.

Lysophosphatidylcholine stimulates monocyte chemoattractant protein-1 gene expression in rat aortic smooth muscle cells.

Rong JX, Berman JW, Taubman MB, Fisher EA

Arteriosclerosis, thrombosis, and vascular biology.. 2002 October 122 (10):1617-23. Epub 1900 01 01.

CCR2 deficiency decreases intimal hyperplasia after arterial injury.

Roque M, Kim WJ, Gazdoin M, Malik A, Reis ED, Fallon JT, Badimon JJ, Charo IF, Taubman MB

Arteriosclerosis, thrombosis, and vascular biology.. 2002 April 122 (4):554-9. Epub 1900 01 01.

Mammalian EGLN genes have distinct patterns of mRNA expression and regulation.

Lieb ME, Menzies K, Moschella MC, Ni R, Taubman MB

Biochemistry and cell biology = Biochimie et biologie cellulaire.. 2002 80 (4):421-6. Epub 1900 01 01.

HIV envelope gp120 activates human arterial smooth muscle cells.

Schecter AD, Berman AB, Yi L, Mosoian A, McManus CM, Berman JW, Klotman ME, Taubman MB

Proceedings of the National Academy of Sciences of the United States of America.. 2001 August 2898 (18):10142-7. Epub 08/14/2001.

Effect of p27 deficiency and rapamycin on intimal hyperplasia: in vivo and in vitro studies using a p27 knockout mouse model.

Roqué M, Reis ED, Cordon-Cardo C, Taubman MB, Fallon JT, Fuster V, Badimon JJ

Laboratory investigation; a journal of technical methods and pathology.. 2001 June 81 (6):895-903. Epub 1900 01 01.

Dexamethasone inhibits macrophage accumulation after balloon arterial injury in cholesterol fed rabbits.

Poon M, Gertz SD, Fallon JT, Wiegman P, Berman JW, Sarembock IJ, Taubman MB

Atherosclerosis.. 2001 April 155 (2):371-80. Epub 1900 01 01.

Expression of Q227L-Galpha(s) inhibits intimal vessel wall hyperplasia after balloon injury.

Holness W, Santore TA, Brown GP, Fallon JT, Taubman MB, Iyengar R

Proceedings of the National Academy of Sciences of the United States of America.. 2001 January 3098 (3):1288-93. Epub 1900 01 01.

Inhibition of tissue factor reduces thrombus formation and intimal hyperplasia after porcine coronary angioplasty.

Roqué M, Reis ED, Fuster V, Padurean A, Fallon JT, Taubman MB, Chesebro JH, Badimon JJ

Journal of the American College of Cardiology.. 2000 December 36 (7):2303-10. Epub 1900 01 01.

Osteopontin deficiency in rat vascular smooth muscle cells is associated with an inability to adhere to collagen and increased apoptosis.

Weintraub AS, Schnapp LM, Lin X, Taubman MB

Laboratory investigation; a journal of technical methods and pathology.. 2000 November 80 (11):1603-15. Epub 1900 01 01.

CC chemokine I-309 is the principal monocyte chemoattractant induced by apolipoprotein(a) in human vascular endothelial cells.

Haque NS, Zhang X, French DL, Li J, Poon M, Fallon JT, Gabel BR, Taubman MB, Koschinsky M, Harpel PC

Circulation.. 2000 August 15102 (7):786-92. Epub 1900 01 01.

Release of active tissue factor by human arterial smooth muscle cells.

Schecter AD, Spirn B, Rossikhina M, Giesen PL, Bogdanov V, Fallon JT, Fisher EA, Schnapp LM, Nemerson Y, Taubman MB

Circulation research.. 2000 July 2187 (2):126-32. Epub 1900 01 01.

Induction of IG9 monocyte adhesion molecule expression in smooth muscle and endothelial cells after balloon arterial injury in cholesterol-fed rabbits.

Calderon TM, Gertz SD, Sarembock IJ, Berliner JA, Fallon JT, Taubman MB, Berman JW

Arteriosclerosis, thrombosis, and vascular biology.. 2000 May 20 (5):1293-300. Epub 1900 01 01.

Intimal tissue factor activity is released from the arterial wall after injury.

Giesen PL, Fyfe BS, Fallon JT, Roque M, Mendlowitz M, Rossikhina M, Guha A, Badimon JJ, Nemerson Y, Taubman MB

Thrombosis and haemostasis.. 2000 April 83 (4):622-8. Epub 1900 01 01.

Human vascular smooth muscle cells possess functional CCR5.

Schecter AD, Calderon TM, Berman AB, McManus CM, Fallon JT, Rossikhina M, Zhao W, Christ G, Berman JW, Taubman MB

The Journal of biological chemistry.. 2000 February 25275 (8):5466-71. Epub 1900 01 01.

Mouse model of femoral artery denudation injury associated with the rapid accumulation of adhesion molecules on the luminal surface and recruitment of neutrophils.

Roque M, Fallon JT, Badimon JJ, Zhang WX, Taubman MB, Reis ED

Arteriosclerosis, thrombosis, and vascular biology.. 2000 February 20 (2):335-42. Epub 1900 01 01.

Trapidil inhibits monocyte chemoattractant protein-1 and macrophage accumulation after balloon arterial injury in rabbits.

Poon M, Cohen J, Siddiqui Z, Fallon JT, Taubman MB

Laboratory investigation; a journal of technical methods and pathology.. 1999 November 79 (11):1369-75. Epub 1900 01 01.

Identification of a novel dexamethasone-sensitive RNA-destabilizing region on rat monocyte chemoattractant protein 1 mRNA.

Poon M, Liu B, Taubman MB

Molecular and cellular biology.. 1999 October 19 (10):6471-8. Epub 1900 01 01.

Dietary lipid lowering reduces tissue factor expression in rabbit atheroma.

Aikawa M, Voglic SJ, Sugiyama S, Rabkin E, Taubman MB, Fallon JT, Libby P

Circulation.. 1999 September 14100 (11):1215-22. Epub 1900 01 01.

Regulation of the procoagulant response to arterial injury.

Taubman MB, Giesen PL, Schecter AD, Nemerson Y

Thrombosis and haemostasis.. 1999 August 82 (2):801-5. Epub 1900 01 01.

SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation.

Moschella MC, Menzies K, Tsao L, Lieb MA, Kohtz JD, Kohtz DS, Taubman MB

Gene expression.. 1999 8 (1):59-66. Epub 1900 01 01.

Platelet-derived growth factor-specific regulation of the JE promoter in rat aortic smooth muscle cells.

Bogdanov VY, Poon M, Taubman MB

The Journal of biological chemistry.. 1998 September 18273 (38):24932-8. Epub 1900 01 01.

Hirudin reduces tissue factor expression in neointima after balloon injury in rabbit femoral and porcine coronary arteries.

Gertz SD, Fallon JT, Gallo R, Taubman MB, Banai S, Barry WL, Gimple LW, Nemerson Y, Thiruvikraman S, Naidu SS, Chesebro JH, Fuster V, Sarembock IJ, Badimon JJ

Circulation.. 1998 August 1198 (6):580-7. Epub 1900 01 01.

Factor Xa generation at the surface of cultured rat vascular smooth muscle cells in an in vitro flow system.

Hall CL, Taubman MB, Nemerson Y, Turitto VT

Journal of biomechanical engineering.. 1998 August 120 (4):484-90. Epub 1900 01 01.

The Pharmacologic Approach to Restenosis: Recent Experiences and Trends.

Taubman MB

The Journal of invasive cardiology.. 1997 December 9 Suppl D :20D-23D. Epub 1900 01 01.

Tissue factor is induced by monocyte chemoattractant protein-1 in human aortic smooth muscle and THP-1 cells.

Schecter AD, Rollins BJ, Zhang YJ, Charo IF, Fallon JT, Rossikhina M, Giesen PL, Nemerson Y, Taubman MB

The Journal of biological chemistry.. 1997 November 7272 (45):28568-73. Epub 1900 01 01.

Tissue factor expression in human arterial smooth muscle cells. TF is present in three cellular pools after growth factor stimulation.

Schecter AD, Giesen PL, Taby O, Rosenfield CL, Rossikhina M, Fyfe BS, Kohtz DS, Fallon JT, Nemerson Y, Taubman MB

The Journal of clinical investigation.. 1997 November 1100 (9):2276-85. Epub 1900 01 01.

Apolipoprotein(a) is a human vascular endothelial cell agonist: studies on the induction in endothelial cells of monocyte chemotactic factor activity.

Poon M, Zhang X, Dunsky K, Taubman MB, Harpel PC

Clinical genetics.. 1997 November 52 (5):308-13. Epub 1900 01 01.

Apolipoprotein(a) induces monocyte chemotactic activity in human vascular endothelial cells.

Poon M, Zhang X, Dunsky KG, Taubman MB, Harpel PC

Circulation.. 1997 October 2196 (8):2514-9. Epub 1900 01 01.

Tissue factor in the pathogenesis of atherosclerosis.

Taubman MB, Fallon JT, Schecter AD, Giesen P, Mendlowitz M, Fyfe BS, Marmur JD, Nemerson Y

Thrombosis and haemostasis.. 1997 July 78 (1):200-4. Epub 1900 01 01.

Rapamycin inhibits vascular smooth muscle cell migration.

Poon M, Marx SO, Gallo R, Badimon JJ, Taubman MB, Marks AR

The Journal of clinical investigation.. 1996 November 1598 (10):2277-83. Epub 1900 01 01.

Cloning of the rat tissue factor cDNA and promoter: identification of a serum-response region.

Taby O, Rosenfield CL, Bogdanov V, Nemerson Y, Taubman MB

Thrombosis and haemostasis.. 1996 November 76 (5):697-702. Epub 1900 01 01.

In situ localization of tissue factor in human atherosclerotic plaques by binding of digoxigenin-labeled factors VIIa and X.

Thiruvikraman SV, Guha A, Roboz J, Taubman MB, Nemerson Y, Fallon JT

Laboratory investigation; a journal of technical methods and pathology.. 1996 October 75 (4):451-61. Epub 1900 01 01.

Identification of active tissue factor in human coronary atheroma.

Marmur JD, Thiruvikraman SV, Fyfe BS, Guha A, Sharma SK, Ambrose JA, Fallon JT, Nemerson Y, Taubman MB

Circulation.. 1996 September 1594 (6):1226-32. Epub 1900 01 01.

Autocrine secretion of osteopontin by vascular smooth muscle cells regulates their adhesion to collagen gels.

Weintraub AS, Giachelli CM, Krauss RS, Almeida M, Taubman MB

The American journal of pathology.. 1996 July 149 (1):259-72. Epub 1900 01 01.

Secretion of monocyte chemotactic activity by cultured rat aortic smooth muscle cells in response to PDGF is due predominantly to the induction of JE/MCP-1.

Poon M, Hsu WC, Bogdanov VY, Taubman MB

The American journal of pathology.. 1996 July 149 (1):307-17. Epub 1900 01 01.

SM-20 is a novel 40-kd protein whose expression in the arterial wall is restricted to smooth muscle.

Wax SD, Tsao L, Lieb ME, Fallon JT, Taubman MB

Laboratory investigation; a journal of technical methods and pathology.. 1996 April 74 (4):797-808. Epub 1900 01 01.

Identification of lysyl oxidase and other platelet-derived growth factor-inducible genes in vascular smooth muscle cells by differential screening.

Green RS, Lieb ME, Weintraub AS, Gacheru SN, Rosenfield CL, Shah S, Kagan HM, Taubman MB

Laboratory investigation; a journal of technical methods and pathology.. 1995 October 73 (4):476-82. Epub 1900 01 01.

Components of the protein synthesis and folding machinery are induced in vascular smooth muscle cells by hypertrophic and hyperplastic agents. Identification by comparative protein phenotyping and microsequencing.

Patton WF, Erdjument-Bromage H, Marks AR, Tempst P, Taubman MB

The Journal of biological chemistry.. 1995 September 8270 (36):21404-10. Epub 1900 01 01.

Lipoprotein(a): searching for a function

Harpel,P. C.; Poon,M.; Zhang,X.; Taubman,M. B.;.

Transactions of the American Clinical and Climatological Association. 1995; 107: 125-133.

Identification of a novel growth factor-responsive gene in vascular smooth muscle cells.

Wax SD, Rosenfield CL, Taubman MB

The Journal of biological chemistry.. 1994 April 29269 (17):13041-7. Epub 1900 01 01.

Cloning and expression of a novel acidic calponin isoform from rat aortic vascular smooth muscle.

Applegate D, Feng W, Green RS, Taubman MB

The Journal of biological chemistry.. 1994 April 8269 (14):10683-90. Epub 1900 01 01.

Tissue factor regulation in vascular smooth muscle: a summary of studies performed using in vivo and in vitro models.

Taubman MB

The American journal of cardiology.. 1993 September 972 (8):55C-60C. Epub 1900 01 01.

Gene induction in vessel wall injury.

Taubman MB

Thrombosis and haemostasis.. 1993 July 170 (1):180-3. Epub 1900 01 01.

Tissue factor is rapidly induced in arterial smooth muscle after balloon injury.

Marmur JD, Rossikhina M, Guha A, Fyfe B, Friedrich V, Mendlowitz M, Nemerson Y, Taubman MB

The Journal of clinical investigation.. 1993 May 91 (5):2253-9. Epub 1900 01 01.

Agonist-mediated tissue factor expression in cultured vascular smooth muscle cells. Role of Ca2+ mobilization and protein kinase C activation.

Taubman MB, Marmur JD, Rosenfield CL, Guha A, Nichtberger S, Nemerson Y

The Journal of clinical investigation.. 1993 February 91 (2):547-52. Epub 1900 01 01.

Development and characterization of a cloned rat pulmonary arterial smooth muscle cell line that maintains differentiated properties through multiple subcultures.

Rothman A, Kulik TJ, Taubman MB, Berk BC, Smith CW, Nadal-Ginard B

Circulation.. 1992 December 86 (6):1977-86. Epub 1900 01 01.

Induction of PDGF-responsive genes in vascular smooth muscle. Implications for the early response to vessel injury.

Marmur JD, Poon M, Rossikhina M, Taubman MB

Circulation.. 1992 December 86 (6 Suppl):III53-60. Epub 1900 01 01.

JE mRNA accumulates rapidly in aortic injury and in platelet-derived growth factor-stimulated vascular smooth muscle cells.

Taubman MB, Rollins BJ, Poon M, Marmur J, Green RS, Berk BC, Nadal-Ginard B

Circulation research.. 1992 February 70 (2):314-25. Epub 1900 01 01.

Expression of cytokine-like genes JE and KC is increased during renal ischemia.

Safirstein R, Megyesi J, Saggi SJ, Price PM, Poon M, Rollins BJ, Taubman MB

The American journal of physiology.. 1991 December 261 (6 Pt 2):F1095-101. Epub 1900 01 01.

In vivo and in vitro inhibition of JE gene expression by glucocorticoids.

Poon M, Megyesi J, Green RS, Zhang H, Rollins BJ, Safirstein R, Taubman MB

The Journal of biological chemistry.. 1991 November 25266 (33):22375-9. Epub 1900 01 01.

Characterization of phosphatidylinositol-specific phospholipase C from cultured vascular smooth muscle cells.

Griendling KK, Taubman MB, Akers M, Mendlowitz M, Alexander RW

The Journal of biological chemistry.. 1991 August 15266 (23):15498-504. Epub 1900 01 01.

The ryanodine receptor/junctional channel complex is regulated by growth factors in a myogenic cell line.

Marks AR, Taubman MB, Saito A, Dai Y, Fleischer S

The Journal of cell biology.. 1991 July 114 (2):303-12. Epub 1900 01 01.

Thrombin-stimulated events in cultured vascular smooth-muscle cells.

Berk BC, Taubman MB, Griendling KK, Cragoe EJ, Fenton JW, Brock TA

The Biochemical journal.. 1991 March 15274 ( Pt 3) :799-805. Epub 1900 01 01.

Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways.

Berk BC, Taubman MB, Cragoe EJ, Fenton JW, Griendling KK

The Journal of biological chemistry.. 1990 October 5265 (28):17334-40. Epub 1900 01 01.

Mammalian nonsarcomeric myosin regulatory light chains are encoded by two differentially regulated and linked genes.

Grant JW, Taubman MB, Church SL, Johnson RL, Nadal-Ginard B

The Journal of cell biology.. 1990 September 111 (3):1127-35. Epub 1900 01 01.

Syndromes of accelerated atherosclerosis: role of vascular injury and smooth muscle cell proliferation.

Ip JH, Fuster V, Badimon L, Badimon J, Taubman MB, Chesebro JH

Journal of the American College of Cardiology.. 1990 June 15 (7):1667-87. Epub 1900 01 01.

Molecular cloning and characterization of the ryanodine receptor/junctional channel complex cDNA from skeletal muscle sarcoplasmic reticulum.

Marks AR, Tempst P, Hwang KS, Taubman MB, Inui M, Chadwick C, Fleischer S, Nadal-Ginard B

Proceedings of the National Academy of Sciences of the United States of America.. 1989 November 86 (22):8683-7. Epub 1900 01 01.

The expression of sarcomeric muscle-specific contractile protein genes in BC3H1 cells: BC3H1 cells resemble skeletal myoblasts that are defective for commitment to terminal differentiation.

Taubman MB, Smith CW, Izumo S, Grant JW, Endo T, Andreadis A, Nadal-Ginard B

The Journal of cell biology.. 1989 May 108 (5):1799-806. Epub 1900 01 01.

Angiotensin II induces c-fos mRNA in aortic smooth muscle. Role of Ca2+ mobilization and protein kinase C activation.

Taubman MB, Berk BC, Izumo S, Tsuda T, Alexander RW, Nadal-Ginard B

The Journal of biological chemistry.. 1989 January 5264 (1):526-30. Epub 1900 01 01.

Cloning and characterization of mammalian myosin regulatory light chain (RLC) cDNA: the RLC gene is expressed in smooth, sarcomeric, and nonmuscle tissues.

Taubman MB, Grant JW, Nadal-Ginard B

The Journal of cell biology.. 1987 June 104 (6):1505-13. Epub 1900 01 01.

The carboxyl fragment released by bacterial collagenase from human type I procollagen: antibodies to the propeptide determinants.

Goldberg BD, Phelps RG, Kessler E, Klein MJ, Taubman MB

Collagen and related research. 1985 November 5 (5):393-404. Epub 1900 01 01.

Epidermal growth factor, a vascular smooth muscle mitogen, induces rat aortic contraction.

Berk BC, Brock TA, Webb RC, Taubman MB, Atkinson WJ, Gimbrone MA, Alexander RW

The Journal of clinical investigation.. 1985 March 75 (3):1083-6. Epub 1900 01 01.

Antigenic relatedness of primate procollagens as determined by a competitive radioimmunoassay

Taubman,M. B.; Goldberg,B.;.

Comparative biochemistry and physiology. B: Comparative biochemistry. 1978; 59(1): 47-49.

Radioimmunoassay of procollagen in serum of patients with Paget's disease of bone.

Taubman MB, Kammerman S, Goldberg B

Proceedings of the Society for Experimental Biology and Medicine.. 1976 June 152 (2):284-7. Epub 1900 01 01.

The processing of procollagen in cultures of human and mouse fibroblasts.

Taubman MB, Goldberg B

Archives of biochemistry and biophysics.. 1976 April 173 (2):490-4. Epub 1900 01 01.

Procollagen peptidase: its mode of action on the native substrate.

Goldberg B, Taubman MB, Radin A

Cell.. 1975 January 4 (1):45-50. Epub 1900 01 01.

Radioimmunoassay for human procollagen.

Taubman MB, Goldberg B, Sherr C

Science.. 1974 December 20186 (4169):1115-7. Epub 1900 01 01.

Isolation of a disulfide-stabilized, three-chain polypeptide fragment unique to the precursor of human collagen.

Sherr CJ, Taubman MB, Goldberg B

The Journal of biological chemistry.. 1973 October 25248 (20):7033-8. Epub 1900 01 01.

Books

Thrombosis and Hemorrhage (2003)

Chapter: Interactions of Coagulation and Fibrinolytic Proteins with the Vessel wall

Authors: Taubman, M.B

Publisher: Lippincott Williams and Wilkins, Philadelphia, PA 2003

Textbook of Cardiovascular Medicine, 2nd Edition (2002)

Chapter: General Techniques in Molecular Cardiology

Authors: Lieb, M.E., and Taubman, M.B

Publisher: Lippincott-Raven Publishers, Philadelphia, PA 2002

Williams Hematology (2001)

Chapter: Thrombosis, Arteriosclerosis, and Coronary Artery Disease

Authors: Taubman, M.B

Publisher: McGraw Hill, NY 2001

Essential Cardiology: Principles and Practice (2000)

Chapter: Thrombosis

Authors: Nemerson, Y., and Taubman, M.B

Publisher: Rosendorff, C. W. B. Saunders, Essential Cardiology: Principles and Practice 2000

Vascular Disease: Molecular Biology and Gene Therapy Protocols (1999)

Chapter: Preparation of cDNA libraries from vascular cells

Authors: Lieb, M.E., and Taubman, M.B

Publisher: Humana Press, Totowa, NJ 1999

Multiple Risk Factors in Cardiovascular Disease, Eds. (1998)

Chapter: Tissue factor and the regulation of arterial thrombosis

Authors: Taubman, M.B.

Publisher: Kluwer Academic Publishers, Dordrecht, The Netherlands 1998

Textbook of Cardiovascular Medicine, Ed (1998)

Chapter: General Techniques in Molecular Cardiology

Authors: Lieb, M.E., and Taubman, M.B.

Publisher: Lippincott-Raven Publishers, Philadelphia, PA 1998

Molecular Biology of Cardiovascular Disease (1997)

Chapter: The extracellular matrix and smooth muscle cell migration

Authors: Weintraub, A.S. and Taubman, M.B.

Publisher: Marcel Dekker, Inc., New York, NY 1997

Molecular Biology of Cardiovascular Disease (1997)

Chapter: The role of tissue factor in arterial thrombosis and atherosclerosis

Authors: 88. Taubman, M.B.

Publisher: Marcel Dekker, Inc., New York, NY 1997

Atherosclerosis X, Eds. (1997)

Chapter: Gene induction in vessel wall injury: implication for restenosis after angioplasty.

Authors: Taubman, M.B., Poon, M., Marmur, J.D., and Wax, S.D.

Publisher: Elsevier Science, B.V., The Netherlands 1997

Coronary balloon angioplasty (1993)

Chapter: Local delivery to the arterial wall: pharmacologic and molecular approaches

Authors: Wolinsky, H., and Taubman, M.B

Publisher: Blackwell Scientific Publications, Inc., Cambridge, MA 1993

Molecular biology of the cardiovascular system (1990)

Chapter: Molecular biology of the vascular smooth muscle contractile apparatus.

Authors: Taubman, M.B

Publisher: Ed. Chien, S., Lea and Febiger, Malvern, PA 1990

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