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Jeanne Holden-Wiltse, M.P.H., M.B.A.

Jeanne Holden-Wiltse, M.P.H., M.B.A.

she/her/hers

Contact

Office (585) 275-0386

About Me

Faculty Appointments

Senior Associate - Department of Clinical and Translational Research (SMD)

Senior Associate - Department of Biostatistics and Computational Biology (SMD) - Joint

Credentials

Education

MBA | Simon School of Business University of Rochester. Executive Leadership. 2017

MPH | University of Michigan. Epidemiology. 1991

BA | Vassar College. Biology. 1985

Publications

Journal Articles

Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial.

Fong Y, Dang L, Zhang B, Fintzi J, Chen S, Wang J, Rouphael NG, Branche AR, Diemert DJ, Falsey AR, Losada C, Baden LR, Frey SE, Whitaker JA, Little SJ, Kamidani S, Walter EB, Novak RM, Rupp R, Jackson LA, Yu C, Magaret CA, Molitor C, Borate B, Babu TM, Kottkamp AC, Luetkemeyer AF, Immergluck LC, Presti RM, Bäcker M, Winokur PL, Mahgoub SM, Goepfert PA, Fusco DN, Atmar RL, Posavad CM, Mu J, Makowski M, Makhene MK, Nayak SU, Roberts PC, Follmann D, Gilbert PB,

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.. 2024 September 26 Epub 09/26/2024.

Investigating Ethical Tradeoffs in Crisis Standards of Care through Simulation of Ventilator Allocation Protocols.

Herington J, Shand J, Holden-Wiltse J, Corbett A, Dees R, Ching CL, Shaw M, Cai X, Zand M

medRxiv : the preprint server for health sciences.. 2024 March 13 Epub 03/13/2024.

Single-Cell Transcriptomic Profiling Identifies Molecular Phenotypes of Newborn Human Lung Cells.

Bhattacharya S, Myers JA, Baker C, Guo M, Danopoulos S, Myers JR, Bandyopadhyay G, Romas ST, Huyck HL, Misra RS, Dutra J, Holden-Wiltse J, McDavid AN, Ashton JM, Al Alam D, Potter SS, Whitsett JA, Xu Y, Pryhuber GS, Mariani TJ

Genes.. 2024 February 2615 (3)Epub 02/26/2024.

RocHealthData.org: Development and usage of a publicly available, geographic source of social determinants of health data.

Holt KD, Roman G, McIntosh L, Kleinsorge J, Holden-Wiltse J, Bennett NM

Journal of clinical and translational science.. 2024 8 (1):e41. Epub 02/15/2024.

Ventilation during COVID-19 in a school for students with intellectual and developmental disabilities (IDD).

Zand MS, Spallina S, Ross A, Zandi K, Pawlowski A, Seplaki CL, Herington J, Corbett AM, Kaukeinen K, Holden-Wiltse J, Freedman EG, Alcantara L, Li D, Cameron A, Beaumont N, Dozier A, Dewhurst S, Foxe JJ

PloS one.. 2024 19 (4):e0291840. Epub 04/03/2024.

Investigating ethical tradeoffs in crisis standards of care through simulation of ventilator allocation protocols.

Herington J, Shand J, Holden-Wiltse J, Corbett A, Dees R, Ching CL, Shaw M, Cai X, Zand M

PloS one.. 2024 19 (9):e0300951. Epub 09/12/2024.

Correction: Investigating ethical tradeoffs in crisis standards of care through simulation of ventilator allocation protocols.

Herington J, Shand J, Holden-Wiltse J, Corbett A, Dees R, Ching CL, Shaw M, Cai X, Zand M

PloS one.. 2024 19 (12):e0315138. Epub 12/03/2024.

Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP).

Jain S, Pei L, Spraggins JM, Angelo M, Carson JP, Gehlenborg N, Ginty F, Gonçalves JP, Hagood JS, Hickey JW, Kelleher NL, Laurent LC, Lin S, Lin Y, Liu H, Naba A, Nakayasu ES, Qian WJ, Radtke A, Robson P, Stockwell BR, Van de Plas R, Vlachos IS, Zhou M, , Börner K, Snyder MP

Nature cell biology.. 2023 August 25 (8):1089-1100. Epub 07/19/2023.

Common Data Element Collection in Underserved School Communities: Challenges and Recommendations.

Uthappa DM, Mann TK, Goldman JL, Schuster JE, Newland JG, Anderson WB, Dozier A, Inkelas M, Foxe JJ, Gwynn L, Gurnett CA, McDaniels-Davidson C, Walsh T, Watterson T, Holden-Wiltse J, Potts JM, D'Agostino EM, Zandi K, Corbett A, Spallina S, DeMuri GP, Wu YP, Pulgaron ER, Kiene SM, Oren E, Allison-Burbank JD, Okihiro M, Lee RE, Johnson SB, Stump TK, Coller RJ, Mast DK, Haroz EE, Kemp S, Benjamin DK, Zimmerman KO

Pediatrics.. 2023 July 1152 (Suppl 1)Epub 1900 01 01.

Aberrant newborn T cell and microbiota developmental trajectories predict respiratory compromise during infancy.

McDavid A, Laniewski N, Grier A, Gill AL, Kessler HA, Huyck H, Carbonell E, Holden-Wiltse J, Bandyopadhyay S, Carnahan J, Dylag AM, Topham DJ, Falsey AR, Caserta MT, Pryhuber GS, Gill SR, Scheible KM

iScience.. 2022 April 1525 (4):104007. Epub 03/01/2022.

Homologous and Heterologous Covid-19 Booster Vaccinations.

Atmar RL, Lyke KE, Deming ME, Jackson LA, Branche AR, El Sahly HM, Rostad CA, Martin JM, Johnston C, Rupp RE, Mulligan MJ, Brady RC, Frenck RW, Bäcker M, Kottkamp AC, Babu TM, Rajakumar K, Edupuganti S, Dobrzynski D, Coler RN, Posavad CM, Archer JI, Crandon S, Nayak SU, Szydlo D, Zemanek JA, Dominguez Islas CP, Brown ER, Suthar MS, McElrath MJ, McDermott AB, O'Connell SE, Montefiori DC, Eaton A, Neuzil KM, Stephens DS, Roberts PC, Beigel JH,

The New England journal of medicine.. 2022 March 17386 (11):1046-1057. Epub 01/26/2022.

A systems genomics approach uncovers molecular associates of RSV severity.

McCall MN, Chu CY, Wang L, Benoodt L, Thakar J, Corbett A, Holden-Wiltse J, Slaunwhite C, Grier A, Gill SR, Falsey AR, Topham DJ, Caserta MT, Walsh EE, Qiu X, Mariani TJ

PLoS computational biology.. 2021 December 17 (12):e1009617. Epub 12/28/2021.

Clinical Characterization and Prediction of Clinical Severity of SARS-CoV-2 Infection Among US Adults Using Data From the US National COVID Cohort Collaborative.

Bennett TD, Moffitt RA, Hajagos JG, Amor B, Anand A, Bissell MM, Bradwell KR, Bremer C, Byrd JB, Denham A, DeWitt PE, Gabriel D, Garibaldi BT, Girvin AT, Guinney J, Hill EL, Hong SS, Jimenez H, Kavuluru R, Kostka K, Lehmann HP, Levitt E, Mallipattu SK, Manna A, McMurry JA, Morris M, Muschelli J, Neumann AJ, Palchuk MB, Pfaff ER, Qian Z, Qureshi N, Russell S, Spratt H, Walden A, Williams AE, Wooldridge JT, Yoo YJ, Zhang XT, Zhu RL, Austin CP, Saltz JH, Gersing KR, Haendel MA, Chute CG,

JAMA network open.. 2021 July 14 (7):e2116901. Epub 07/01/2021.

Temporal Dysbiosis of Infant Nasal Microbiota Relative to Respiratory Syncytial Virus Infection.

Grier A, Gill AL, Kessler HA, Corbett A, Bandyopadhyay S, Java J, Holden-Wiltse J, Falsey AR, Topham DJ, Mariani TJ, Caserta MT, Walsh EE, Gill SR

The Journal of infectious diseases.. 2021 May 20223 (9):1650-1658. Epub 1900 01 01.

Airway Gene Expression Correlates of Respiratory Syncytial Virus Disease Severity and Microbiome Composition in Infants.

Chu CY, Qiu X, McCall MN, Wang L, Corbett A, Holden-Wiltse J, Slaunwhite C, Grier A, Gill SR, Pryhuber GS, Falsey AR, Topham DJ, Caserta MT, Walsh EE, Mariani TJ

The Journal of infectious diseases.. 2021 May 20223 (9):1639-1649. Epub 1900 01 01.

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.

Muus C, Luecken MD, Eraslan G, Sikkema L, Waghray A, Heimberg G, Kobayashi Y, Vaishnav ED, Subramanian A, Smillie C, Jagadeesh KA, Duong ET, Fiskin E, Triglia ET, Ansari M, Cai P, Lin B, Buchanan J, Chen S, Shu J, Haber AL, Chung H, Montoro DT, Adams T, Aliee H, Allon SJ, Andrusivova Z, Angelidis I, Ashenberg O, Bassler K, Bécavin C, Benhar I, Bergenstråhle J, Bergenstråhle L, Bolt L, Braun E, Bui LT, Callori S, Chaffin M, Chichelnitskiy E, Chiou J, Conlon TM, Cuoco MS, Cuomo ASE, Deprez M, Duclos G, Fine D, Fischer DS, Ghazanfar S, Gillich A, Giotti B, Gould J, Guo M, Gutierrez AJ, Habermann AC, Harvey T, He P, Hou X, Hu L, Hu Y, Jaiswal A, Ji L, Jiang P, Kapellos TS, Kuo CS, Larsson L, Leney-Greene MA, Lim K, Litvi?uková M, Ludwig LS, Lukassen S, Luo W, Maatz H, Madissoon E, Mamanova L, Manakongtreecheep K, Leroy S, Mayr CH, Mbano IM, McAdams AM, Nabhan AN, Nyquist SK, Penland L, Poirion OB, Poli S, Qi C, Queen R, Reichart D, Rosas I, Schupp JC, Shea CV, Shi X, Sinha R, Sit RV, Slowikowski K, Slyper M, Smith NP, Sountoulidis A, Strunz M, Sullivan TB, Sun D, Talavera-López C, Tan P, Tantivit J, Travaglini KJ, Tucker NR, Vernon KA, Wadsworth MH, Waldman J, Wang X, Xu K, Yan W, Zhao W, Ziegler CGK, ,

Nature medicine.. 2021 March 27 (3):546-559. Epub 03/02/2021.

Airway gene-expression classifiers for respiratory syncytial virus (RSV) disease severity in infants.

Wang L, Chu CY, McCall MN, Slaunwhite C, Holden-Wiltse J, Corbett A, Falsey AR, Topham DJ, Caserta MT, Mariani TJ, Walsh EE, Qiu X

BMC medical genomics.. 2021 February 2514 (1):57. Epub 02/25/2021.

Eight practices for data management to enable team data science.

McDavid A, Corbett AM, Dutra JL, Straw AG, Topham DJ, Pryhuber GS, Caserta MT, Gill SR, Scheible KM, Holden-Wiltse J

Journal of clinical and translational science.. 2020 June 235 (1):e14. Epub 06/23/2020.

Characterizing Emerging Canine H3 Influenza Viruses.

Martinez-Sobrido L, Blanco-Lobo P, Rodriguez L, Fitzgerald T, Zhang H, Nguyen P, Anderson CS, Holden-Wiltse J, Bandyopadhyay S, Nogales A, DeDiego ML, Wasik BR, Miller BL, Henry C, Wilson PC, Sangster MY, Treanor JJ, Topham DJ, Byrd-Leotis L, Steinhauer DA, Cummings RD, Luczo JM, Tompkins SM, Sakamoto K, Jones CA, Steel J, Lowen AC, Danzy S, Tao H, Fink AL, Klein SL, Wohlgemuth N, Fenstermacher KJ, El Najjar F, Pekosz A, Sauer L, Lewis MK, Shaw-Saliba K, Rothman RE, Liu ZY, Chen KF, Parrish CR, Voorhees IEH, Kawaoka Y, Neumann G, Chiba S, Fan S, Hatta M, Kong H, Zhong G, Wang G, Uccellini MB, García-Sastre A, Perez DR, Ferreri LM, Herfst S, Richard M, Fouchier R, Burke D, Pattinson D, Smith DJ, Meliopoulos V, Freiden P, Livingston B, Sharp B, Cherry S, Dib JC, Yang G, Russell CJ, Barman S, Webby RJ, Krauss S, Danner A, Woodard K, Peiris M, Perera RAPM, Chan MCW, Govorkova EA, Marathe BM, Pascua PNQ, Smith G, Li YT, Thomas PG, Schultz-Cherry S

PLoS pathogens.. 2020 April 16 (4):e1008409. Epub 04/14/2020.

Measuring the Severity of Respiratory Illness in the First 2 Years of Life in Preterm and Term Infants.

Caserta MT, Yang H, Bandyopadhyay S, Qiu X, Gill SR, Java J, McDavid A, Falsey AR, Topham DJ, Holden-Wiltse J, Scheible K, Pryhuber G

The Journal of pediatrics.. 2019 November 214 :12-19.e3. Epub 07/31/2019.

Comprehensive anatomic ontologies for lung development: A comparison of alveolar formation and maturation within mouse and human lung.

Pan H, Deutsch GH, Wert SE, ,

Journal of biomedical semantics. 2019 October 2410 (1):18. Epub 10/24/2019.

Microbiome-Transcriptome Interactions Related to Severity of Respiratory Syncytial Virus Infection.

Sonawane AR, Tian L, Chu CY, Qiu X, Wang L, Holden-Wiltse J, Grier A, Gill SR, Caserta MT, Falsey AR, Topham DJ, Walsh EE, Mariani TJ, Weiss ST, Silverman EK, Glass K, Liu YY

Scientific reports.. 2019 September 259 (1):13824. Epub 09/25/2019.

Aims, Study Design, and Enrollment Results From the Assessing Predictors of Infant Respiratory Syncytial Virus Effects and Severity Study.

Walsh EE, Mariani TJ, Chu C, Grier A, Gill SR, Qiu X, Wang L, Holden-Wiltse J, Corbett A, Thakar J, Benoodt L, McCall MN, Topham DJ, Falsey AR, Caserta MT

JMIR research protocols.. 2019 June 68 (6):e12907. Epub 06/06/2019.

Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals.

Henry C, Zheng NY, Huang M, Cabanov A, Rojas KT, Kaur K, Andrews SF, Palm AE, Chen YQ, Li Y, Hoskova K, Utset HA, Vieira MC, Wrammert J, Ahmed R, Holden-Wiltse J, Topham DJ, Treanor JJ, Ertl HC, Schmader KE, Cobey S, Krammer F, Hensley SE, Greenberg H, He XS, Wilson PC

Cell host & microbe.. 2019 March 1325 (3):357-366.e6. Epub 02/19/2019.

Come from away: Best practices in mini-sabbaticals for the development of young investigators: a White Paper by the SEQUIN (mini-Sabbatical Evaluation and QUality ImprovemeNt) Group.

Pillinger MH, Lemon SC, Zand MS, Foster PJ, Merchant JS, Kimberly R, Allison J, Cronstein BN, Galeano C, Holden-Wiltse J, Trayhan M, White RJ, Davin A, Saag KG

Journal of clinical and translational science.. 2019 February 3 (1):37-44. Epub 1900 01 01.

Neonatal gut and respiratory microbiota: coordinated development through time and space.

Grier A, McDavid A, Wang B, Qiu X, Java J, Bandyopadhyay S, Yang H, Holden-Wiltse J, Kessler HA, Gill AL, Huyck H, Falsey AR, Topham DJ, Scheible KM, Caserta MT, Pryhuber GS, Gill SR

Microbiome.. 2018 October 266 (1):193. Epub 10/26/2018.

Dissociation, cellular isolation, and initial molecular characterization of neonatal and pediatric human lung tissues.

Bandyopadhyay G, Huyck HL, Misra RS, Bhattacharya S, Wang Q, Mereness J, Lillis JA, Myers JR, Ashton J, Bushnell T, Cochran M, Holden-Wiltse J, Katzman P, Deutsch GH, Whitsett JA, Xu Y, Mariani TJ, Pryhuber GS

American journal of physiology. Lung cellular and molecular physiology.. 2018 October 1315 (4):L576-L583. Epub 07/05/2018.

Effect of prior vaccination on carriage rates of Streptococcus pneumoniae in older adults: A longitudinal surveillance study.

Branche AR, Yang H, Java J, Wiltse-Holden J, Topham DJ, Peasley M, Frost MR, Nahm MH, Falsey AR

Vaccine.. 2018 July 536 (29):4304-4310. Epub 06/02/2018.

T-Cell Responses in Adults During Natural Respiratory Syncytial Virus Infection.

Roumanes D, Falsey AR, Quataert S, Secor-Socha S, Lee FE, Yang H, Bandyopadhyay S, Holden-Wiltse J, Topham DJ, Walsh EE

The Journal of infectious diseases.. 2018 July 2218 (3):418-428. Epub 1900 01 01.

Virus-Specific Antibody, Viral Load, and Disease Severity in Respiratory Syncytial Virus Infection.

Walsh EE, Wang L, Falsey AR, Qiu X, Corbett A, Holden-Wiltse J, Mariani TJ, Topham DJ, Caserta MT

The Journal of infectious diseases.. 2018 June 20218 (2):208-217. Epub 1900 01 01.

T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy.

Scheible KM, Emo J, Laniewski N, Baran AM, Peterson DR, Holden-Wiltse J, Bandyopadhyay S, Straw AG, Huyck H, Ashton JM, Tripi KS, Arul K, Werner E, Scalise T, Maffett D, Caserta M, Ryan RM, Reynolds AM, Ren CL, Topham DJ, Mariani TJ, Pryhuber GS

JCI insight.. 2018 February 223 (4)Epub 02/22/2018.

Maximum Likelihood Estimation of Titer via a Power Family of Four-Parameter Logistic Model.

Yang H, Holden-Wiltse J, Topham DJ, Treanor J

Journal of biopharmaceutical statistics.. 2018 28 (3):492-500. Epub 09/05/2017.

Impact of prematurity and nutrition on the developing gut microbiome and preterm infant growth.

Grier A, Qiu X, Bandyopadhyay S, Holden-Wiltse J, Kessler HA, Gill AL, Hamilton B, Huyck H, Misra S, Mariani TJ, Ryan RM, Scholer L, Scheible KM, Lee YH, Caserta MT, Pryhuber GS, Gill SR

Microbiome.. 2017 December 115 (1):158. Epub 12/11/2017.

Association of Dynamic Changes in the CD4 T-Cell Transcriptome With Disease Severity During Primary Respiratory Syncytial Virus Infection in Young Infants.

Mariani TJ, Qiu X, Chu CY, Wang L, Thakar J, Holden-Wiltse J, Corbett A, Topham DJ, Falsey AR, Caserta MT, Walsh EE

The Journal of infectious diseases.. 2017 November 15216 (8):1027-1037. Epub 1900 01 01.

Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness.

Bhattacharya S, Rosenberg AF, Peterson DR, Grzesik K, Baran AM, Ashton JM, Gill SR, Corbett AM, Holden-Wiltse J, Topham DJ, Walsh EE, Mariani TJ, Falsey AR

Scientific reports.. 2017 July 267 (1):6548. Epub 07/26/2017.

Development of a Global Respiratory Severity Score for Respiratory Syncytial Virus Infection in Infants.

Caserta MT, Qiu X, Tesini B, Wang L, Murphy A, Corbett A, Falsey AR, Holden-Wiltse J, Walsh EE

The Journal of infectious diseases.. 2017 March 1215 (5):750-756. Epub 1900 01 01.

Viral Respiratory Infections in Preterm Infants during and after Hospitalization.

Caserta MT, Yang H, Gill SR, Holden-Wiltse J, Pryhuber G

The Journal of pediatrics.. 2017 March 182 :53-58.e3. Epub 12/30/2016.

The Healthy Infant Nasal Transcriptome: A Benchmark Study.

Chu CY, Qiu X, Wang L, Bhattacharya S, Lofthus G, Corbett A, Holden-Wiltse J, Grier A, Tesini B, Gill SR, Falsey AR, Caserta MT, Walsh EE, Mariani TJ

Scientific reports.. 2016 September 236 :33994. Epub 09/23/2016.

Directed selection of influenza virus produces antigenic variants that match circulating human virus isolates and escape from vaccine-mediated immune protection.

DeDiego ML, Anderson CS, Yang H, Holden-Wiltse J, Fitzgerald T, Treanor JJ, Topham DJ

Immunology.. 2016 June 148 (2):160-73. Epub 03/30/2016.

An improved method for estimating antibody titers in microneutralization assay using green fluorescent protein.

Yang H, Baker SF, González ME, Topham DJ, Martínez-Sobrido L, Zand M, Holden-Wiltse J, Wu H

Journal of biopharmaceutical statistics.. 2016 26 (3):409-20. Epub 05/26/2015.

Developmentally determined reduction in CD31 during gestation is associated with CD8+ T cell effector differentiation in preterm infants.

Scheible KM, Emo J, Yang H, Holden-Wiltse J, Straw A, Huyck H, Misra S, Topham DJ, Ryan RM, Reynolds AM, Mariani TJ, Pryhuber GS

Clinical immunology : the official journal of the Clinical Immunology Society.. 2015 December 161 (2):65-74. Epub 07/29/2015.

Modeling the dynamics and migratory pathways of virus-specific antibody-secreting cell populations in primary influenza infection.

Miao H, Sangster MY, Livingstone AM, Hilchey SP, Zhang L, Topham DJ, Mosmann TR, Holden-Wiltse J, Perelson AS, Wu H, Zand MS

PloS one.. 2014 9 (8):e104781. Epub 08/29/2014.

Statistical estimation & inference of cell counts from ELISPOT limiting dilution assays.

Yang H, Topham DJ, Holden-Wiltse J, Wu H

Journal of biopharmaceutical statistics.. 2013 23 (4):921-36. Epub 1900 01 01.

High-resolution temporal response patterns to influenza vaccine reveal a distinct human plasma cell gene signature.

Henn AD, Wu S, Qiu X, Ruda M, Stover M, Yang H, Liu Z, Welle SL, Holden-Wiltse J, Wu H, Zand MS

Scientific reports.. 2013 3 :2327. Epub 1900 01 01.

A strategy to model nonmonotonic dose-response curve and estimate IC50.

Zhang H, Holden-Wiltse J, Wang J, Liang H

PloS one.. 2013 8 (8):e69301. Epub 08/01/2013.

Modeling of influenza-specific CD8+ T cells during the primary response indicates that the spleen is a major source of effectors.

Wu H, Kumar A, Miao H, Holden-Wiltse J, Mosmann TR, Livingstone AM, Belz GT, Perelson AS, Zand MS, Topham DJ

The Journal of immunology : official journal of the American Association of Immunologists.. 2011 November 1187 (9):4474-82. Epub 09/23/2011.

A DYNAMIC BAYESIAN NONLINEAR MIXED-EFFECTS MODEL OF HIV RESPONSE INCORPORATING MEDICATION ADHERENCE, DRUG RESISTANCE AND COVARIATES().

Huang Y, Wu H, Holden-Wiltse J, Acosta EP

The annals of applied statistics.. 2011 5 (1):551-577. Epub 1900 01 01.

Human immunodeficiency virus type 1 protease inhibitor drug-resistant mutants give discordant results when compared in single-cycle and multiple-cycle fitness assays.

Dykes C, Wu H, Sims M, Holden-Wiltse J, Demeter LM

Journal of clinical microbiology.. 2010 November 48 (11):4035-43. Epub 09/08/2010.

Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus.

Miao H, Hollenbaugh JA, Zand MS, Holden-Wiltse J, Mosmann TR, Perelson AS, Wu H, Topham DJ

Journal of virology.. 2010 July 84 (13):6687-98. Epub 04/21/2010.

B cell responses to H5 influenza HA in human subjects vaccinated with a drifted variant.

Baer J, Santiago F, Yang H, Wu H, Jeanne-Holden-Wiltse , Treanor J, Topham DJ

Vaccine.. 2010 January 2228 (4):907-15. Epub 11/21/2009.

Simulation and prediction of the adaptive immune response to influenza A virus infection.

Lee HY, Topham DJ, Park SY, Hollenbaugh J, Treanor J, Mosmann TR, Jin X, Ward B, Miao H, Holden-Wiltse J, Perelson AS, Zand M, Wu H

Journal of virology.. 2009 July 83 (14):7151-65. Epub 05/13/2009.

Safety and immunogenicity of a baculovirus-expressed hemagglutinin influenza vaccine: a randomized controlled trial.

Treanor JJ, Schiff GM, Hayden FG, Brady RC, Hay CM, Meyer AL, Holden-Wiltse J, Liang H, Gilbert A, Cox M

JAMA.. 2007 April 11297 (14):1577-82. Epub 1900 01 01.

Dose-escalation, phase I/II study of azithromycin and pyrimethamine for the treatment of toxoplasmic encephalitis in AIDS.

Jacobson JM, Hafner R, Remington J, Farthing C, Holden-Wiltse J, Bosler EM, Harris C, Jayaweera DT, Roque C, Luft BJ,

AIDS.. 2001 March 3015 (5):583-9. Epub 1900 01 01.

Delavirdine susceptibilities and associated reverse transcriptase mutations in human immunodeficiency virus type 1 isolates from patients in a phase I/II trial of delavirdine monotherapy (ACTG 260).

Demeter LM, Shafer RW, Meehan PM, Holden-Wiltse J, Fischl MA, Freimuth WW, Para MF, Reichman RC

Antimicrobial agents and chemotherapy.. 2000 March 44 (3):794-7. Epub 1900 01 01.

ACTG 260: a randomized, phase I-II, dose-ranging trial of the anti-human immunodeficiency virus activity of delavirdine monotherapy. The AIDS Clinical Trials Group Protocol 260 Team.

Para MF, Meehan P, Holden-Wiltse J, Fischl M, Morse G, Shafer R, Demeter LM, Wood K, Nevin T, Virani-Ketter N, Freimuth WW

Antimicrobial agents and chemotherapy.. 1999 June 43 (6):1373-8. Epub 1900 01 01.

Phase I studies of hypericin, the active compound in St. John's Wort, as an antiretroviral agent in HIV-infected adults. AIDS Clinical Trials Group Protocols 150 and 258.

Gulick RM, McAuliffe V, Holden-Wiltse J, Crumpacker C, Liebes L, Stein DS, Meehan P, Hussey S, Forcht J, Valentine FT

Annals of internal medicine.. 1999 March 16130 (6):510-4. Epub 1900 01 01.

Phase I study of atevirdine mesylate (U-87201E) monotherapy in HIV-1-infected patients.

Demeter LM, Meehan PM, Morse G, Fischl MA, Para M, Powderly W, Leedom J, Holden-Wiltse J, Greisberger C, Wood K, Timpone J, Wathen LK, Nevin T, Resnick L, Batts DH, Reichman RC

Journal of acquired immune deficiency syndromes and human

Fumagillin analog in the treatment of Kaposi's sarcoma: a phase I AIDS Clinical Trial Group study. AIDS Clinical Trial Group No. 215 Team.

Dezube BJ, Von Roenn JH, Holden-Wiltse J, Cheung TW, Remick SC, Cooley TP, Moore J, Sommadossi JP, Shriver SL, Suckow CW, Gill PS

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 1998 April 16 (4):1444-9. Epub 1900 01 01.

Safety and antiviral activity of combination therapy with zidovudine, zalcitabine, and two doses of interferon-alpha2a in patients with HIV. AIDS Clinical Trials Group Study 197.

Fischl MA, Richman DD, Saag M, Meng TC, Squires KE, Holden-Wiltse J, Meehan PM

Journal of acquired immune deficiency syndromes and human

Phase I/II study of the toxicity, pharmacokinetics, and activity of the HIV protease inhibitor SC-52151.

Fischl MA, Richman DD, Flexner C, Para MF, Haubrich R, Karim A, Yeramian P, Holden-Wiltse J, Meehan PM

Journal of acquired immune deficiency syndromes and human

A phase-I study of the safety, pharmacokinetics, and antiviral activity of combination didanosine and ribavirin in patients with HIV-1 disease. AIDS Clinical Trials Group 231 Protocol Team.

Japour AJ, Lertora JJ, Meehan PM, Erice A, Connor JD, Griffith BP, Clax PA, Holden-Wiltse J, Hussey S, Walesky M, Cooney E, Pollard R, Timpone J, McLaren C, Johanneson N, Wood K, Booth D, Bassiakos Y, Crumpacker CS

Journal of acquired immune deficiency syndromes and human

Taste responses and food preferences in obese women: effects of weight cycling.

Drewnowski A, Holden-Wiltse J

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.. 1992 September 16 (9):639-48. Epub 1900 01 01.

Food preferences in human obesity: carbohydrates versus fats.

Drewnowski A, Kurth C, Holden-Wiltse J, Saari J

Appetite.. 1992 June 18 (3):207-21. Epub 1900 01 01.